9,407 research outputs found
HR\u27s Role in Organizational Development
Presented at the Nonprofit Human Resources Symposium, San Diego, CA on June 3rd, 2011.https://digital.sandiego.edu/npi-bpl-humanresource/1002/thumbnail.jp
Kaplan: An Unhurried View of Copyright
A Review of An Unhurried View of Copyright by Benjamin Kapla
Identification of the growth arrest and DNA damage protein GADD34 in the normal human heart and demonstration of alterations in expression following myocardial ischaemia
Growth arrest and DNA damage protein 34 (GADD34) is a multifunctional protein upregulated in response to cellular stress and is believed to mediate DNA repair and restore protein synthesis. In the present study we have examined GADD34 immunoreactivity in human myocardial tissue at defined survival times following cardiac arrest and determined alterations in expression following ischaemia. In the normal human heart, GADD34 immunoreactivity was generally intense and present within most cells. GADD34 immunoreactivity was downregulated in tissue displaying ischaemic damage and remained intense in adjacent non-infarcted tissue. Unlike brain, GADD34 was not found to be upregulated in the peri-infarct zone. Cells displaying apoptotic changes were located in regions displaying reduced GADD34 immunoreactivity. In the brain, it is thought that GADD34 supports re-initiation of protein synthesis following ischaemia. Similarly, GADD34 may perform important functions in cardiac tissue in response to ischaemia
Arbitrary precision composite pulses for NMR quantum computing
We discuss the implementation of arbitrary precision composite pulses
developed using the methods of Brown et al. [Phys. Rev. A 70 (2004) 052318]. We
give explicit results for pulse sequences designed to tackle both the simple
case of pulse length errors and for the more complex case of off-resonance
errors. The results are developed in the context of NMR quantum computation,
but could be applied more widely.Comment: 16 pages elsart, no figures. In press at Journal of Magnetic
resonanc
Wright & Miller: Federal Practice and Procedure, Civil Procedure
A Review of Federal Practice and Procedure, Civil Procedure Vol. 4 & 5 by Charles Alan Wright and Arthur R. Mille
Whole family-based physical activity promotion intervention: the Families Reporting Every Step to Health pilot randomised controlled trial protocol
Introduction : Family-based physical activity (PA) interventions present a promising avenue to promote children’s activity, however, high-quality experimental research is lacking. This paper describes the protocol for the FRESH (Families Reporting Every Step to Health) pilot trial, a child-led family-based PA intervention delivered online. Methods and analysis : FRESH is a three-armed, parallel-group, randomised controlled pilot trial using a 1:1:1 allocation ratio with follow-up assessments at 8- and 52-weeks post-baseline. Families will be eligible if a minimum of one child in school Years 3-6 (aged 7-11 years) and at least one adult responsible for that child are willing to participate. Family members can take part in the intervention irrespective of their participation in the accompanying evaluation and vice versa. Following baseline assessment, families will be randomly allocated to one of three arms: (1) FRESH, (2) pedometer-only, or (3) no-intervention control. All family members in the pedometer-only and FRESH arms receive pedometers and generic PA promotion information. FRESH families additionally receive access to the intervention website; allowing participants to select step challenges to ‘travel’ to target cities around the world, log steps, and track progress as they virtually globetrot. Control families will receive no treatment. All family members will be eligible to participate in the evaluation with two follow-ups (8 and 52 weeks). Physical (e.g., fitness, blood pressure), psychosocial (e.g., social support), and behavioural (e.g., objectively-measured family PA) measures will be collected each time point. At 8-week follow-up, a mixed-methods process evaluation will be conducted (questionnaires and family focus groups) assessing acceptability of the intervention and evaluation. FRESH families’ website engagement will also be explored. Ethics and dissemination : This study received ethical approval from the Ethics Committee for the School of the Humanities and Social Sciences at the University of Cambridge. Findings will be disseminated via peer-reviewed publications, conferences, and to participating families
The Organizational Action Research Model
This chapter proposes a paradigm, which empowers practitioners to practice research to meet their needs and to advance the profession to which they belong. It proposes the integration of practitioner and researcher role as an alternative to the fragmented model that currently exists. In doing so, it draws much from the past tradition of the action researchers as well as the science approach espoused by others. In this way, the needs of individual managers to evaluate their espoused theories and their theories-in-use can be undertaken so that their organizations can function more realistically and can respond more effectively to the need for self-examination and change
Colorado Deer Hunting Experiences
Those responsible for managing environmental resources, like big game, have often posed questions regarding how best to manage and allocate the resource to “provide benefits to people.” One approach to obtaining information for answering these questions is based on consumer behavior concepts and research. Our consumer-oriented approach to deriving management information for environmental resources, particularly game and other recreational resources, rests on ideas conceptualized by Wagar (1966) and having their theoretical base in psychology’s expectancy-value theory (Lawler 1973). The general theoretical orientation we follow is described in Driver and Brown (1975). We also acknowledge a debt to the multiple satisfactions approach to game management articulated by Hendee (1974). The management orientation of this paper suggests that managers should produce opportunities for game-related recreation which recognize the multiple dimensions of the experience. It is the experience that is the important product of recreation, and quality experiences are a function of how well the consumer’s desired satisfactions are fulfilled. Within this orientation, this paper reports characteristics of the Colorado deer hunter population in terms of the kinds of satisfaction that make up deer hunting experiences. In doing so, the usefulness of cluster analytic techniques for social research in wildlife management is illustrated. The information and analytical techniques discussed in this paper have implications for resource valuation, resource allocation, user management, and related aspects of wildlife planning and management
The Occurrence Rate of Earth Analog Planets Orbiting Sunlike Stars
Kepler is a space telescope that searches Sun-like stars for planets. Its
major goal is to determine {\eta}_Earth, the fraction of Sunlike stars that
have planets like Earth. When a planet 'transits' or moves in front of a star,
Kepler can measure the concomitant dimming of the starlight. From analysis of
the first four months of those measurements for over 150,000 stars, Kepler's
science team has determined sizes, surface temperatures, orbit sizes and
periods for over a thousand new planet candidates. In this paper, we
characterize the period probability distribution function of the super-Earth
and Neptune planet candidates with periods up to 132 days, and find three
distinct period regimes. For candidates with periods below 3 days the density
increases sharply with increasing period; for periods between 3 and 30 days the
density rises more gradually with increasing period, and for periods longer
than 30 days, the density drops gradually with increasing period. We estimate
that 1% to 3% of stars like the Sun are expected to have Earth analog planets,
based on the Kepler data release of Feb 2011. This estimate of is based on
extrapolation from a fiducial subsample of the Kepler planet candidates that we
chose to be nominally 'complete' (i.e., no missed detections) to the realm of
the Earth-like planets, by means of simple power law models. The accuracy of
the extrapolation will improve as more data from the Kepler mission is folded
in. Accurate knowledge of {\eta}_Earth is essential for the planning of future
missions that will image and take spectra of Earthlike planets. Our result that
Earths are relatively scarce means that a substantial effort will be needed to
identify suitable target stars prior to these future missions.Comment: Accepted for publication in the Astrophysical Journal. 19 pages, 8
figures. Minor text revisions, as requested by the scientific editor.
Included an additional figure. No changes in the scientific result
An Efficient Automated Validation Procedure for Exoplanet Transit Candidates
Surveys searching for transiting exoplanets have found many more candidates
than they have been able to confirm as true planets. This situation is
especially acute with the Kepler survey, which has found over 2300 candidates
but has confirmed only 77 planets to date. I present here a general procedure
that can quickly be applied to any planet candidate to calculate its false
positive probability. This procedure takes into account the period, depth,
duration, and shape of the signal; the colors of the target star; arbitrary
spectroscopic or imaging follow-up observations; and informed assumptions about
the populations and distributions of field stars and multiple-star properties.
I also introduce the concept of the "specific occurrence rate," which allows
for the calculation of the FPP without relying on an assumed planet radius
function. Applying these methods to a sample of known Kepler planets, I
demonstrate that many signals can be validated with very limited follow-up
observations: in most cases with only a spectrum and an AO image. Additionally,
I demonstrate that this procedure can reliably identify false positive signals.
Because of the computational efficiency of this analysis, it is feasible to
apply it to all Kepler planet candidates in the near future, and it will
streamline the follow-up efforts for Kepler and other current and future
transit surveys.Comment: accepted to Ap
- …