Morphological patterns of lip prints in an Iranian population

Lip prints are verified to be unique to an individual and stable over time; hence they have potential for human identification purposes. The aim of this study was to assess the individuality and variability of lip prints in an Iranian population for the first time. We also sought to assess the possibility of sex determination via lip printing. Lip prints of 96 individuals including 22 males and 74 females were recorded on a plain white paper using a dark-colored lipstick and 50 mm of Scotch tape. Each lip print was divided into six sextants and studied independently by two observers using a magnifying lens to examine the lip grooves. The Suzuki and Tsuchihashi’s classification was used to define the lip patterns and the data were statistically analyzed. In the present study, no identically similar lip prints were observed. Type V was the most predominant pattern recorded in the study sample (33.16%), followed by type I (24.13%), type II (18.75%), type IV (11.63%), type I’ (9.72%) and type III (2.60%). In addition, no statistically significant difference was observed in the lip print patterns of males and females. It can be concluded that lip prints are unique and their analysis may enable human identification

Topographic Features of Five K-file Brands in Iranian Market: A Scanning Electron Microscopic Study

Introduction: Endodontic files which are used to clean and shape the root canal space differ from each other regarding technical specifications. Recently, K-type files are repeatedly studied on their cutting efficiency. This study aims to evaluate the tip design and cutting efficiency of 5 brands of K-files, available in Iran dental market (naming Dentsply, Thomas, Mani, Perfect and Larmrose). Methods and Materials: In this descriptive study, topographic features of file tips were investigated by the scanning electron microscope (SEM). Those features included tip symmetry, tip design, tip angle, and the distance from the tip to the lowest flute. SEM images (×250 magnification) of files were prepared. Statistical tests (Fisher's exact test, Chi-square, ANOVA, and t test) were used and P<0.05 was considered as significant. Results: Dentsply files had the most number of morphologically pyramidal sharp tips and the greatest tip angles. However, Larmrose files were the most frequent files having cutting sharp tips. Symmetrical tips existed among 100% of Dentsply and Mani brands. No significant differences were found with respect to distance from the file tip to the lowermost flute between different file brands of this study (P=0.2, One way ANOVA). Conclusion: Dentsply and Mani files possessed the most symmetrical tips and greatest tip angles. With respect to tip length, all 5 brands were satisfactory. However, neither of 5 brands evaluated topographically were outstanding in every aspect.Keywords: Endodontic K-files; Scanning Electron Microscopy; Topograph

Can the body slope of interference screw affect initial stability of reconstructed anterior cruciate ligament?: An in-vitro investigation

© The Author(s). 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License. https://creativecommons.org/licenses/by/4.0/Background: Superior biomechanical performance of tapered interference screws, compared with non-tapered screws, with reference to the anterior cruciate ligament (ACL) reconstruction process, has been reported in the literature. However, the effect of tapered interference screw’s body slope on the initial stability of ACL is poorly understood. Thus, the main goal of this study was to investigate the effect of the interference screw's body slope on the initial stability of the reconstructed ACL. Methods: Based on the best screw-bone tunnel diameter ratios in non-tapered screws, two different tapered interference screws were designed and fabricated. The diameters of both screws were equal to bone tunnel diameter in one-third of their length from screw tip, then they were gradually increased by 1mm, in the lower slope (LSTIS), and 2 mm, in the higher slope (HSTIS) screws. To simulate the ACL reconstruction, sixteen soft tissue grafts were fixed, using HSTIS and LSTIS, in synthetic bone blocks. Through applying sub-failure cyclic incremental tensile load, graft-bone-screw construct's stiffness and graft laxity in each cycle, also through applying subsequent step of loading graft to the failure, maximum load to failure, and graft’s mode of failure were determined. Accordingly, the performance of the fabricated interference screws was compared with each other. Results: HSTIS provides a greater graft-bone-screw construct stiffness, and a lower graft laxity, compared to LSTIS. Moreover, transverse rupture of graft fibers for LSTIS, and necking of graft in the HSTIS group were the major types of grafts' failure. Conclusion: HSTIS better replicates the intact ACL's behavior, compared to LSTIS, by causing less damage in graft's fibers; reducing graft laxity; and increasing fixation stability. Nonetheless, finding the optimal slope remains as an unknown and can be the subject of future studies.Peer reviewedFinal Published versio

Palisaded Encapsulated Neuroma of the Tongue Clinically Mimicking a Pyogenic Granuloma: A Case Report and Review of Literature

Palisaded encapsulated (solitary circumscribed) neuromas (PENs) are relatively common intraoral neurogenic tumors, which occur most frequently on the hard palate. Herein, we describe the clinicopathological characteristics of a palisaded encapsulated neuroma of the tongue. This tumor was an exophytic sessile mass measuring 0.3× 0.4 cm with rubbery consistency on the anterior one-third of the dorsum of the tongue. The tumor was excised under the impression of a pyogenic granuloma (PG). No recurrence was reported at 12 months postoperatively. Histopathological examination showed a well-circumscribed mass that composed of interlacing fascicles of spindle cells. The cells were S-100 positive. The nuclei, showing parallel orientation within the fascicles, were wavy and pointed and showed no sign of mitotic activity. Giemsa staining revealed no mast cells within the stroma

Early post-operative performance of an anatomically designed hybrid thread interference screw for ACL reconstruction: A comparative study

© 2022 Elsevier Ltd. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1016/j.jbiomech.2022.111031Although the anterior cruciate ligament (ACL) reconstruction using interference screw is a well-accepted surgical procedure, patients still suffer graft failure in the initial rehabilitation phase. Graft fixation stability of a newly designed anatomical hybrid thread tapered interference screw (AHTTIS) was compared with a conventional standard one (CSIS) by conducting in-vitro mechanical tests. According to the CSIS manufacturer’s instruction, eight tapered bone tunnels, matching AHTTIS geometry, and eight straight cylindrical tunnels were drilled in artificial bone blocks. Bovine tendon grafts were fixed using AHTTIS and CSIS in their corresponding bone tunnels. Each graft was subjected to a pre-load, a dynamic cyclic sinusoidal tensile load, and a tensile pullout load. Aggregate graft displacement relative to the bone tunnel under dynamic cyclic load, load corresponding to a 3 mm displacement; load and displacement at yield and ultimate failure of the graft; and graft-bone-screw stiffness resulted from pullout tests were recorded. There were no significant differences between recorded parameters of the two groups, except the graft displacements relative to the bone tunnel at ultimate failure load (8.35 ± 3.03 mm versus 5.28 ± 1.37 mm) and at the yield point (7.73 ± 3.02 mm versus 4.59 ± 1.25 mm) (P < 0.05), which were both significantly greater for the AHTTIS group. Considering all tests were made in the worst-case scenario of fixation of an interference screw, i.e., the employed synthetic bone just mimicked cancellous bone, graft fixation with the AHTTIS is practical. However, in the case of employing high strain rate loads on AHTTIS, further considerations are needed to reduce the side effect of slippage of the graft.Peer reviewe

Detection and identification of Prevotella Melaninogenica in saliva samples of patients with ulcerative colitis

Background: Ulcerative colitis (UC) is a long-term inflammatory bowel disease (IBD) caused by abnormal immune responses, leading to inflammation and scarring in the large intestine. The bacteria Prevotella melaninogenica, found in the intestine and mouth, may contribute to UC. This study focuses on the detection of P. melaninogenica in the saliva of UC patients and compares them with the healthy control (HC) group. Methods: The present study was a case-control study including 40 UC patients and 40 healthy controls (HCs) with an average age of 43.0 3± 10.3. This study used a real-time PCR test to investigate the frequency and average number of P. melaninogenica from the 16S rRNA gene sequence of P. melaninogenica in both groups. Results: P. melaninogenica was more frequent in UC patients (77.5%) than HCs (45%) (p = 0.003). The patient group had more bacteria (339.31 ± 1082.29) than HCs (61.29 ± 154.03) (p = 0.005). Women in the UC group had more P. melaninogenica (492.35 ± 1427.61) than the control group (56.98 ± 123.50) (p = 0.0342). Similarly, men in the UC group (262.85 ± 664.97) had more bacteria than the control group (72.62 ± 222.76) (p = 0.015). Conclusion: The current study showed that dysbiosis in P. melaninogenica, a bacterium in human saliva, could be important in the development of UC. Further investigation is needed to evaluate its use as a potential biomarker in the UC

The inhibitory effects of carvacrol, nystatin, and their combination on oral candidiasis isolates

Abstract Background Candida, a common oral microbiota, can cause opportunistic fungal infections. With rising Candida infections and limited effective antifungals, new treatments are needed. This study investigates carvacrol essential oil’s effect on oral candidiasis, alone and with nystatin, compared to nystatin alone. Materials and methods In this study, oral samples were collected from dental clinic patients, especially denture users. The presence of Candida was confirmed and cultured from these samples. Candidiasis was detected by observing Candida colonies. Drug sensitivity was tested on 100 positive samples. The minimum concentration of inhibition and lethality of each isolate was evaluated using nystatin and carvacrol. The results were compared using two-way analysis of variance. Finally, the minimum inhibitory concentration (MIC) of nystatin and carvacrol was calculated individually and in combination. Results The present study found that Candida albicans and non-albicans species were equally prevalent. Carvacrol showed significant biological activity against all Candida species, with an average MTT of 50.01%. The average MIC value of carvacrol was 24.96 µg/ml, indicating its potential to inhibit Candida growth. The mean Minimum Fungicidal Concentration (MFC) value of carvacrol was 23.48 µg/ml, suggesting its effectiveness in killing the fungi. Conclusion The study’s findings reveal that the MIC of carvacrol was significantly lower than that of nystatin and the combination of nystatin and carvacrol. This suggests that carvacrol holds potential as an effective herbal remedy for candidiasis

Assessment of a combined mouthwash on pain relief in pericoronitis: a randomized clinical study

Abstract Background Pericoronitis, an inflammation near wisdom teeth, often occurs when they are partially emerged, especially in the lower jaw. Commonly, the gingiva partially envelops the tooth. Treatments vary from gingival surgery to extraction. This study assessed the efficacy of a mouthwash with Chlorhexidine, Benzydamine, Nanosilver, Amoxicillin, and Metronidazole for pain reduction and enhancement of maximum mouth opening in acute pericoronitis cases. Materials and methods In this randomized controlled clinical trial conducted at the Gorgan Dental Faculty, 48 pericoronitis patients were randomized into two groups. The control group used a 0.12% chlorhexidine mouthwash, while the case group used a mouthwash containing Chlorhexidine, Benzydamine, Nanosilver, Amoxicillin, and Metronidazole. The study recorded Visual Analog Scale (VAS) scores for 7 days, and Maximum mouth opening (MMO) was measured at the start and after 7 days. The analysis was performed using SPSS v20. Results In this study, we compared the effects of a combined mouthwash with those of a chlorhexidine mouthwash on pericoronitis in 48 patients, with an average age of 21.56 years. No significant difference in pain reduction was observed between the groups; however, both groups exhibited decreased pain and improved MMO post-treatment. The gender distribution was balanced across both groups. Conclusion The results indicate that both chlorhexidine mouthwash and combined mouthwash significantly improved maximum mouth opening. Nonetheless, there were no notable differences in efficacy between the two groups. These findings suggest that these mouthwashes may be beneficial for oral hygiene, warranting further in-depth research. Trial registration Registered on 12/03/2023, registration number IRCT20230104057046N1

A review on the oxidative stress in recurrent aphtous stomatitis

Background and Aims: The purpose of the present study was to review the studies regarding serological and salivary oxidant / antioxidant status in patients with recurrent aphthous stomatitis (RAS).   Materials and Methods: The literature was searched using key words RAS, Antioxidants, Saliva, Hematinic (s) and Hematinic Acid in the last 10 years, particularly the recent 3 years (2010-2013). At total of 37 clinical trials, 18 case-control articles were selected and evaluated; fulfilling the requirements as the RAS patients having at least 3 oral aphthous attack per year. The exclusion criteria included systemic as well as periodontal diseases, iron deficiency associated anemia, medication usage and smoking.   Conclusion: Almost all lipid-peroxidation studies in serum and saliva were manifested by an increase of malondialdehyde (MDA) concentration in RAS patients compared with controls. This would indicate the role of reactive oxygen species (ROS) in the etiology of the disease. Serum trace elements (Zn, Se) were reduced and Cu was increased in RAS patients in comparison with control individuals. A decreased serum superoxide dismutase (SOD) and an increased salivary SOD were observed in all RAS patients. Catalase (CAT) and uric acid (UA) analyses were non-inclusive. Levels of paraoxonase and arylesterase as well as antioxidant vitamins (A, E, C) were lower in RAS patients than that of controls