2,498 research outputs found

    Rad62 protein functionally and physically associates with the Smc5/Smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast

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    Smc5 and Smc6 proteins form a heterodimeric SMC (structural maintenance of chromosome) protein complex like SMC1-SMC3 cohesin and SMC2-SMC4 condensin, and they associate with non-SMC proteins Nse1 and Nse2 stably and Rad60 transiently. This multiprotein complex plays an essential role in maintaining chromosome integrity and repairing DNA double strand breaks (DSBs). This study characterizes a Schizosaccharomyces pombe mutant rad62-1, which is hypersensitive to methyl methanesulfonate (MMS) and synthetically lethal with rad2 (a feature of recombination mutants). rad62-1 is hypersensitive to UV and gamma rays, epistatic with rhp51, and defective in repair of DSBs. rad62 is essential for viability and genetically interacts with rad60, smc6, and brc1. Rad62 protein physically associates with the Smc5-6 complex. rad62-1 is synthetically lethal with mutations in the genes promoting recovery from stalled replication, such as rqh1, srs2, and mus81, and those involved in nucleotide excision repair like rad13 and rad16. These results suggest that Rad62, like Rad60, in conjunction with the Smc5-6 complex, plays an essential role in maintaining chromosome integrity and recovery from stalled replication by recombination

    Chiral Symmetry and N*(1440) -> N pi pi Decay

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    The N*(1440) -> N pi pi decay is studied by making use of the chiral reduction formula. This formula suggests a scalar-isoscalar pion-baryon contact interaction which is absent in the recent study of Hern{\'a}ndez et al. The contact interaction is introduced into their model, and is found to be necessary for the simultaneous description of g_{RN pi pi} and the pi-pi and pi-N invariant mass distributions.Comment: 12 page

    Anomalous increase of solar anisotropy above 150GV in 1981-1983

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    An analysis was carried out of the observed data with Nagoya (surface). Misato (34mwe) and Sakashita (80mwe) multidirectional muon telescope, for the solar activity maximum period of 1978-1983. These data respond to primaries extending over the median rigidity range 60GV to 600GV. The observed amplitude at Sakashita station in 1981-1983 increased, especially in 1982; the amplitude is twice as large as that in 1978-1980, when those at Nagoya and Misato stations are nearly the same as those in 1978-1980. Uni-directional anisotropy is derived by the best fit method by assuming the flat rigidity spectrum with the upper cutoff rigidity Pu. The value of Pu obtained is 270GV in 1981-1983 and 150GV in 1978-1980

    Solar tri-diurnal variation of cosmic rays in a wide range of rigidity

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    Solar tri-diurnal variations of cosmic rays have been analyzed in a wide range of rigidity, using data from neutron monitors, and the surface and underground muon telescopes for the period 1978-1983. The rigidity spectrum of the anisotropy in space is assumed to be of power-exponential type as (P/gamma P sub o) to the gamma exp (gamma-P/P sub o). By means of the best-fit method between the observed and the expected variations, it is obtained that the spectrum has a peak at P (=gamma P sub o) approx = 90 GV, where gamma=approx 3.0 and P sub o approx. 30 GV. The phase in space of the tri-diurnal variation is also obtained as 7.0 hr (15 hr and 23 hr LT), which is quite different from that of approx. 1 hr. arising from the axisymmetric distribution of cosmic rays with respect to the IMF

    Mechanisms of spin-dependent dark conductivity in films of a soluble fullerene derivative under bipolar injection

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    pre-printWe report room-temperature pulsed electrically detected magnetic resonance measurements of the dark conductivity of films of the fullerene derivative [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) under bipolar (electron-hole) and unipolar (electron-rich) injection conditions. Directly after material deposition, no detectable spin-dependent processes are observed, yet after storage under ambient conditions for more than a day, two distinct spin-dependent mechanisms are found under bipolar injection, suggesting the involvement of degradation-induced electronic states. Spin-Rabi beat oscillation measurements show that at least one of these processes is due to weakly spin-coupled pairs with s = 1/2. The absence of these signals when hole injection is impeded by a barrier suggests that they are due to spin-dependent recombination. The presence of recombination confirms that fullerenes are both electron and hole acceptors, with important consequences for the design, operation, and understanding of plastic solar cells. Electron-hole recombination can occur within homogeneous domains of either the donor or the acceptor of the bulk heterojunction structure, constituting an important dissipative channel in addition to the established interfacial bimolecular recombination loss

    Observation of Root Rot and Internal Breakdown of Redclover (\u3ci\u3eTrifolium pratense\u3c/i\u3e L.) in the 3rd Year

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    Two red clover (Trifolium pratense L.) cultivars; Hokuseki and Merviot were surveyed growth habits and deterioration at the crown and taproot in the 3rd year. Each cutting plants were marked and measured the plant height and dry matter weight. After 3rd cutting of the 3rd year, plants were digged out and scored the degree of root rot and internal break down (no symptom: 0-severe damaged: 5). The severe damaged plants at the 3rd cutting tend to have larger plant size at the 1st cutting. And other root development traits during growth were observed

    Critical evaluation of attosecond time delays retrieved from photoelectron streaking measurements

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    Citation: Wei, H., Morishita, T., & Lin, C. D. (2016). Critical evaluation of attosecond time delays retrieved from photoelectron streaking measurements. Physical Review A - Atomic, Molecular, and Optical Physics, 93(5). doi:10.1103/PhysRevA.93.053412A photoelectron streaking experiment which was conceived as a means to extract the electron wave packet of single-photon ionization has also been employed to retrieve time delays in the fundamental photoemission processes. The discrepancies between the time delays thus measured and those from many sophisticated theoretical calculations have generated a great deal of controversy in recent years. Here we present a careful examination of the methods that were used to retrieve the time delays and demonstrate the difficulty of achieving an accuracy of the retrieved time delays of a few to tens of attoseconds in typical streaking measurements. The difficulty owes more to the lower sensitivity of the streaking spectra to the phase of the photoionization transition dipole than to the spectral phase of the attosecond light pulse in the experiment. The retrieved time delay contains extra errors when the attochirp of the attosecond pulse is large so that the dipole phase becomes negligible compared to it. © 2016 American Physical Society

    Capacity building in Ocean Bathymetry: The Nippon Foundation GEBCO Training Programme at the University of New Hampshire

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    A successful Capacity Building project in hydrography is underway at the University of New Hampshire. Organised by the General Bathymetric Chart of the Oceans and sponsored by the Nippon Foundation, the programme trains hydrographers and other marine scientists in bathymetric mapping. Participants are formally prepared to produce bathymetric maps when they return to their home countries through a combination of graduate level courses and workshops, practical field training, participation in deep ocean research cruises, working visits to other laboratories and institutions, focused lectures from visiting experts, and the preparation of a bathymetry map of their area from public domain data. Intangible but necessary preparation includes the networking with professionals in bathymetry and related fields within Ocean Mapping, and the building of a cadre of graduates who will form the basis of international bathymetric mapping in the future
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