La síndrome del Burnout en el professional d'infermeria

Màster en Administració i Gestió en Cures d'Infermeria de l'E.U. Santa Madrona, 2005, Director: José Tejad

Guía para madres y padres de bebés prematuros durante la hospitalización

YesEsta guía complementa el seguimiento y apoyo profesional durante la hospitalización inicial, facilitando el refuerzo de las indicaciones profesionales y la autonomía y confianza de padres y madres para el afrontamiento saludable y satisfactorio del nacimiento y la crianza de su hijo o hija

Sesiones grupales dirigidas a madres y padres de bebés prematuros: Guía para profesionales

YesPrograma grupal para padres y madres de bebés ingresados donde se aborden sus inquietudes y necesidades en un espacio común

Programa andaluz para la promoción de la parentalidad positiva en nacimientos prematuros

En el marco del proyecto para la promoción de la parentalidad positiva en el sistema sanitario andaluz conocido como el Proyecto Apego, desarrollado anteriormente en este monográfico, surge una estrategia específica para promover el ejercicio positivo de la parentalidad en padres y madres de bebés prematuros. Una propuesta dirigida a cubrir las necesidades de estos bebés y sus familias tanto durante su estancia en las Unidades Neonatales como tras el alta, en el hogar familiar. Con este objetivo, se elabora una serie de materiales que intentan promover la autonomía y la confianza de padres y madres en el afrontamiento y cuidado saludable de su bebé prematuro, así como apoyar y complementar el trabajo de seguimiento que los profesionales de Neonatología realizan con estos bebés y sus familias. Los materiales se concretan en dos guías para padres y madres de bebés prematuros (una centrada en el tiempo de hospitalización y la otra en lo que acontece o puede acontecer tras el alta hospitalaria), una guía para el trabajo de los profesionales en las sesiones grupales con las familias y un vídeo dirigido a las familias. Los materiales persiguen promover la parentalidad positiva y un desarrollo más óptimo y saludable tanto de los bebés prematuros como de sus familias.In the framework of the project for the promotion of the positive parenting in the Andalusian health system known as The Programme Attachment, developed earlier in this monographic, arises a specific strategy to promote the positive exercise of parenthood in premature children. This is a proposal to meet the needs of these babies and their families during their stay in neonatal units and after discharge, in the family home. In order to meet this objective, a series of materials that aim to promote the autonomy and the confidence of parents in healthy premature baby care is elaborated. In addition, the program aims to complement the work of monitoring made by professionals in the field of Neonatology with premature babies and their families. Materials developed are realized in two guides for parents of premature babies (during hospitalisation and following discharge from hospital), a guide for professionals for work in group sessions with families and a video aimed at families. Those materials pursue promote the parenting positive and a development more optimal and healthy both of them babies premature as of their families.Consejería de Salud de la Junta de Andalucía 68/83 1255/0075Consejería de Salud de la Junta de Andalucía 68/83 2387/029

Distribution of the volatiles fraction in different tissues of Capsicum fruits

This work has been partially financed by INIA through Project RTA2010-00038-C03-03Moreno Peris, E.; Gonzalez Más, MC.; Fita, A.; Prohens Tomás, J.; Rodríguez Burruezo, A. (2011). Distribution of the volatiles fraction in different tissues of Capsicum fruits. Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca : Horticulture. 68(1):532-533. http://hdl.handle.net/10251/62874S53253368

Cardiovascular-related proteomic changes in ECFCs exposed to the serum of COVID-19 patients

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection significantly affects the cardiovascular system, causing vascular damage and thromboembolic events in critical patients. Endothelial dysfunction represents one of the first steps in response to COVID-19 that might lead to cardiovascular complications and long-term sequelae. However, despite the enormous efforts in the last two years, the molecular mechanisms involved in such processes remain poorly understood. Herein, we analyzed the protein changes taking place in endothelial colony forming cells (ECFCs) after the incubation with the serum from individuals infected with COVID-19, whether asymptomatic or critical patients, by application of a label free-quantitative proteomics approach. Specifically, ECFCs from healthy individuals were incubated ex-vivo with the serum of either COVID-19 negative donors (PCR-/IgG-, n:8), COVID-19 asymptomatic donors at different infective stages (PCR+/ IgG-, n:8and PCR-/IgG+, n:8), or hospitalized critical COVID-19 patients (n:8), followed by proteomics analysis. In total, 590 proteins were differentially expressed in ECFCs in response to all infected serums. Predictive analysis highlighted several proteins like CAPN5, SURF4, LAMP2 or MT-ND1, as highly discriminating features between the groups compared. Protein changes correlated with viral infection, RNA metabolism or autophagy, among others. Remarkably, the angiogenic potential of ECFCs in response to the infected serums was impaired, and many of the protein alterations in response to the serum of critical patients were associated with cardiovascular-related pathologies.This study was supported by GLOBALCAJA-Ayuda COVID-19; and Fondo Supera COVID-19, funded by Banco Santander and CRUE universidades, Ref. IPSA-COVID-19, and the Institute of Health Carlos III, ISCIII (PI18-00427, PI20-00716), co-funded by European Regional Development “A way to make Europe”

Endocannabinoid regulation of amyloid-induced neuroinflammation

The modulation of endocannabinoid (EC) levels and the activation of cannabinoid receptors are seen as promising therapeutic strategies in a variety of diseases, including Alzheimer’s disease (AD). We aimed to evaluate the effect of the pharmacological and genetic inhibiton of anandamide (AEA)-degrading enzyme in a mouse model of AD (5xFAD). Pharmacological inhibition of the fatty acid amide hydrolase (FAAH) had little impact on the expression of key enzymes and cytokines as well as on the cognitive impairment and plaque deposition and gliosis in 5xFAD mice. CB1 blockade exacerbated inflammation in this transgenic mouse model of AD. The genetic inactivation of FAAH led to increases in the expression of inflammatory cytokines. At the same time, FAAH-null 5xFAD mice exhibited a behavioral improvement in spatial memory that was independent of the level of anxiety and was not CB1-mediated. Finally, mice lacking FAAH showed diminished soluble amyloid levels, neuritic plaques and gliosis. These data reinforce the notion of a role for the endocannabinoid system in neuroinflammation and open new perspectives on the relevance of modulating endocannabinoid levels in the inflammed brain.pre-print687 K