Post-sternotomy pain syndrome following cardiac surgery. case report

Over 2 million people undergo sternotomy worldwide for heart surgery each year, and many develop post-sternotomy pain syndrome (PSPS) which persists in the anterior thorax. In some patients, PSPS lasts for many years or suddenly reappears a long time after the sternotomy. The exact etiology of PSPS is unknown. This article presents a case report of a patient with a diagnosis of PSPS (after cardiac surgery 4 years prior) for whom an osteopathic approach was used, which successfully eliminated the pain. In a previous study, we demonstrated that this osteopathic procedure could reduce sternal pain associated with a recent surgical wound. Further efforts are needed to understand the reasons for PSPS. In light of new scientific data, these osteopathic techniques could contribute to a multidisciplinary approach to solve the proble

Social-Aware Stateless Forwarding in Pocket Switched Networks

Several social-aware routing protocols for pocket switched networks have been recently introduced in the literature. The main idea underlying these protocols is to exploit state information (e.g., history of past encounters) to deduce information on the social structure of the network, and to optimize routing based on this information. While social-aware routing protocols have been shown to have superior performance to social-oblivious, stateless routing protocols such as, e.g., BinarySW, the improvement comes at the cost of considerable storage overhead required on the nodes, which is instead not required for stateless approaches. So, whether the benefits of social-aware routing protocols would still be present when storage capacity at the nodes is constrained is not clear. In this paper we present SANE, the first forwarding mechanism that combines the advantages of both social-aware and stateless approaches. SANE is based on the observation-that we validate on real-world traces-that individuals with similar interests tend to meet more often. In our approach, individuals (network members) are characterized by their interest profile, a compact representation of their interests. By implementing a simple interest profile similarity based forwarding rule, SANE is free of network state information, thus overcoming the storage capacity problem with existing social-aware approaches. Through extensive experiments, we show the superiority of social-aware, stateless forwarding over existing stateful, social-aware and stateless, social-oblivious routing approaches. An important byproduct of our interest-based approach is that it easily enables innovative routing primitives, such as interest-casting. An interest-casting protocol is also introduced in this paper, and extensively evaluated through experiments based on both real-world and synthetic mobility traces

Italian codified hashtags for weather warning on Twitter – who is really using them?

Abstract. During emergencies, an increasing number of messages are shared through social media platforms, becoming a primary source of information for lay people and emergency managers. Weather services and institutions have started to employ social media to deliver weather warnings even if sometimes this communication lacks in strategy. In Twitter, for example, hashtagging is very important to associate messages with certain topics; in recent years, codified hashtagging is emerging as a practical way to coordinate Twitter conversations during emergencies and quickly retrieve relevant information. In 2014, a syntax for codified hashtags for weather warning was proposed in Italy: a list of 20 hashtags, realized by combining #allertameteo (weather warning) + XXX, where final letters code the regional identification. This contribution presents a monitoring of Twitter usage of weather warning codified hashtags in Italy (since July 2015) and an analysis of different contexts. Twitter messages were retrieved using TwitterVigilance, a multi-users platform to crawl Twitter data, collect and store messages and perform quantitative analytics, about users, hashtags, tweets/retweets volumes. The Codified Hashtags data set is presented and discussed with main analytics and evaluation of regional contexts where it was successfully employed

Willage: A Two-Tiered Peer-to-Peer Resource Sharing Platform for Wireless Mesh Community Networks

The success of experiences such as Seattle and Houston Wireless has attracted the attention on the so called wireless mesh community networks. These are wireless multihop networks spontaneously deployed by users willing to share communication resources. Due to the community spirit characterizing such networks, it is likely that users will be willing to share other resources besides communication resources, such as data, images, music, movies, disk quotas for distributed backup, and so on. In other words, it is expected that peer-to-peer applications will be deployed in such type of networks. In this paper we propose Willage, a platform for resource localization in wireless mesh community networks with mobile users. The platform is based on a two-tiered architecture: resources are made available at the lower tier, which is composed of mobile terminals, whereas information on their localization is managed at the upper layer, which is composed of wireless mesh routers. We also introduce Georoy, an algorithm for the efficient retrieval of the information on resource localization based on the Viceroy algorithm. Simulation results show that Willage achieves its goal of enabling efficient and scalable peer-to-peer resource sharing in wireless mesh community networks

First-Line Chemotherapy for HER-2–Negative Metastatic Breast Cancer Patients Who Received Anthracyclines as Adjuvant Treatment

Learning Objectives After completing this course, the reader will be able to: Discuss the value of retreatment with anthracyclines for HER-2–negative metastatic breast cancer patients who received anthracyclines as adjuvant treatment.Discuss the role of liposomal anthracyclines, taxanes, and combinations without anthracyclines and taxanes, or innovative treatments, including target-based agents.Comment on the weakness and quality of available evidence. Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.co

Joint use of eddy current imaging and fuzzy similarities to assess the integrity of steel plates

AbstractSteel plates bi-axially loaded are characterized by mechanical deformations whose 2D image representations are very difficult to achieve. In this work, the authors propose an innovative approach based on eddy current techniques for obtaining 2D electrical maps to assess the mechanical integrity of a steel plate. The procedure, also exploiting fuzzy similarity computations, translates the problem of the assessment of the mechanical integrity of a steel plate into a suitable classification problem. The results obtained by this proposed procedure show performances comparable to those provided by well-established soft computing approaches with a higher computational complexity

Air temperature-related human health outcomes: Current impact and estimations of future risks in Central Italy

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Quantitative evaluation of RASSF1A methylation in the non-lesional, regenerative and neoplastic liver

BACKGROUND: Epigenetic changes during ageing and their relationship with cancer are under the focus of intense research. RASSF1A and NORE1A are novel genes acting in concert in the proapoptotic pathway of the RAS signalling. While NORE1A has not been previously investigated in the human liver, recent reports have suggested that RASSF1A is frequently epigenetically methylated not only in HCC but also in the cirrhotic liver. METHODS: To address whether epigenetic changes take place in connection to age and/or to the underlying disease, we investigated RASSF1A and NORE1A gene promoter methylation by conventional methylation specific PCR and Real-Time MSP in a series of hepatitic and non-hepatitic livers harboring regenerative/hyperplastic (cirrhosis/focal nodular hyperplasia), dysplastic (large regenerative, low and high grade dysplastic nodules) and neoplastic (hepatocellular adenoma and carcinoma) growths. RESULTS: In the hepatitic liver (chronic hepatitic/cirrhosis, hepatocellular nodules and HCC) we found widespread RASSF1A gene promoter methylation with a methylation index that increased from regenerative conditions (cirrhosis) to hepatocellular nodules (p < 0.01) to HCC (p < 0.001). In the non-hepatitic liver a consistent pattern of gene methylation was also found in both lesional (focal nodular hyperplasia and hepatocellular adenoma) and non-lesional tissue. Specifically, hepatocellular adenomas (HA) showed a methylation index significantly higher than that detected in focal nodular hyperplasia (FNH) (p < 0.01) and in non-lesional tissue (p < 0.001). In non-lesional liver also the methylation index gradually increased by ageing (p = 0.002), suggesting a progressive spreading of methylated cells over time. As opposed to RASSF1A gene promoter methylation, NORE1A gene was never found epigenetically alterated in both hepatitic and non-hepatitic liver. CONCLUSION: We have shown that in non-lesional, regenerative and neoplastic liver the RASSF1A gene is increasingly methylated, that this condition takes place as an age-related phenomenon and that the early setting and spreading over time of an epigenetically methylated hepatocyte subpopulation, might be related to liver tumorigenesis

Studi limnologici sul bacino del Lago di Candia. Attivit? 2009

No abstract availabl