6,040 research outputs found

    More a marathon than a hurdle: towards children’s informed consent in a study on safety

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    Informed consent is critical in research with children. Although much has been written about the need to see consent as an ongoing process, less has considered how to do it in practice. This article reflects on the authors’ experiences of conducting a piece of research focusing on children’s experiences of safety from abuse within institutional contexts. It draws on feedback provided by participants and the guidance of three Children’s Reference Groups. The importance of presenting information in accessible and appropriate ways, of providing opportunities for participants to negotiate their participation and for in-the-moment challenges be dealt with collaboratively and reflexively are stressed. To illustrate our approach, we provide a number of consent tools and describe how they were utilised

    Ireland – 2018

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    Reappraising Threat: How to Optimize Performance Under Pressure

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    Competitive situations often hinge on one pressurized moment. In these situations, individuals' psychophysiological states determine performance, with a challenge state associated with better performance than a threat state. But what can be done if an individual experiences a threat state? This study examined one potential solution: arousal reappraisal. Fifty participants received either arousal reappraisal or control instructions before performing a pressurized, single-trial, motor task. Although both groups initially displayed cardiovascular responses consistent with a threat state, the reappraisal group displayed a cardiovascular response more reflective of a challenge state (relatively higher cardiac output and/or lower total peripheral resistance) after the reappraisal manipulation. Furthermore, despite performing similarly at baseline, the reappraisal group outperformed the control group during the pressurized task. The results demonstrate that encouraging individuals to interpret heightened physiological arousal as a tool that can help maximize performance can result in more adaptive cardiovascular responses and motor performance under pressure

    Mosaic agriculture: a guide to irrigated crop and forage production in northern WA

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    The Bulletin is a comprehensive guide for pastoralists, agronomists, agribusiness and the broader community on the growing of irrigated crops and pastures within a rangeland pastoral setting. Dispersed irrigation developments on stations throughout the northern rangelands (sometimes referred to as mosaic agriculture) has created opportunities for the introduction of more productive forage species and pastoralists can now grow high quality forage for 12 months of the year. This can help to overcome the key constraint of traditional pastoral systems, the low quality of the feed over the dry season that typically results in stock losing condition.https://researchlibrary.agric.wa.gov.au/bulletins/1271/thumbnail.jp

    Planar Embeddings with Small and Uniform Faces

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    Motivated by finding planar embeddings that lead to drawings with favorable aesthetics, we study the problems MINMAXFACE and UNIFORMFACES of embedding a given biconnected multi-graph such that the largest face is as small as possible and such that all faces have the same size, respectively. We prove a complexity dichotomy for MINMAXFACE and show that deciding whether the maximum is at most kk is polynomial-time solvable for k≤4k \leq 4 and NP-complete for k≥5k \geq 5. Further, we give a 6-approximation for minimizing the maximum face in a planar embedding. For UNIFORMFACES, we show that the problem is NP-complete for odd k≥7k \geq 7 and even k≥10k \geq 10. Moreover, we characterize the biconnected planar multi-graphs admitting 3- and 4-uniform embeddings (in a kk-uniform embedding all faces have size kk) and give an efficient algorithm for testing the existence of a 6-uniform embedding.Comment: 23 pages, 5 figures, extended version of 'Planar Embeddings with Small and Uniform Faces' (The 25th International Symposium on Algorithms and Computation, 2014

    The absolute position of a resonance peak

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    It is common practice in scattering theory to correlate between the position of a resonance peak in the cross section and the real part of a complex energy of a pole of the scattering amplitude. In this work we show that the resonance peak position appears at the absolute value of the pole's complex energy rather than its real part. We further demonstrate that a local theory of resonances can still be used even in cases previously thought impossible

    Expandable and Rapidly Differentiating Human Induced Neural Stem Cell Lines for Multiple Tissue Engineering Applications

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    Limited availability of human neurons poses a significant barrier to progress in biological and preclinical studies of the human nervous system. Current stem cell-based approaches of neuron generation are still hindered by prolonged culture requirements, protocol complexity, and variability in neuronal differentiation. Here we establish stable human induced neural stem cell (hiNSC) lines through the direct reprogramming of neonatal fibroblasts and adult adipose-derived stem cells. These hiNSCs can be passaged indefinitely and cryopreserved as colonies. Independently of media composition, hiNSCs robustly differentiate into TUJ1-positive neurons within 4 days, making them ideal for innervated co-cultures. In vivo, hiNSCs migrate, engraft, and contribute to both central and peripheral nervous systems. Lastly, we demonstrate utility of hiNSCs in a 3D human brain model. This method provides a valuable interdisciplinary tool that could be used to develop drug screening applications as well as patient-specific disease models related to disorders of innervation and the brain

    Modular differential equations for characters of RCFT

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    We discuss methods, based on the theory of vector-valued modular forms, to determine all modular differential equations satisfied by the conformal characters of RCFT; these modular equations are related to the null vector relations of the operator algebra. Besides describing effective algorithmic procedures, we illustrate our methods on an explicit example.Comment: 13 page

    Cavity formation on the surface of a body entering water with deceleration

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    The two-dimensional water entry of a rigid symmetric body with account for cavity formation on the body surface is studied. Initially the liquid is at rest and occupies the lower half plane. The rigid symmetric body touches the liquid free surface at a single point and then starts suddenly to penetrate the liquid vertically with a time-varying speed. We study the effect of the body deceleration on the pressure distribution in the flow region. It is shown that, in addition to the high pressures expected from the theory of impact, the pressure on the body surface can later decrease to sub-atmospheric levels. The creation of a cavity due to such low pressures is considered. The cavity starts at the lowest point of the body and spreads along the body surface forming a thin space between a new free surface and the body. Within the linearised hydrodynamic problem, the positions of the two turnover points at the periphery of the wetted area are determined by Wagner’s condition. The ends of the cavity’s free surface are modelled by the Brillouin–Villat condition. The pressure in the cavity is assumed to be a prescribed constant, which is a parameter of the model. The hydrodynamic problem is reduced to a system of integral and differential equations with respect to several functions of time. Results are presented for constant deceleration of two body shapes: a parabola and a wedge. The general formulation made also embraces conditions where the body is free to decelerate under the total fluid force. Contrasts are drawn between results from the present model and a simpler model in which the cavity formation is suppressed. It is shown that the expansion of the cavity can be significantly slower than the expansion of the corresponding zone of sub-atmospheric pressure in the simpler model. For forced motion and cavity pressure close to atmospheric, the cavity grows until almost complete detachment of the fluid from the body. In the problem of free motion of the body, cavitation with vapour pressure in the cavity is achievable only for extremely large impact velocities
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