E_11 and M Theory

We argue that eleven dimensional supergravity can be described by a non-linear realisation based on the group E_{11}. This requires a formulation of eleven dimensional supergravity in which the gravitational degrees of freedom are described by two fields which are related by duality. We show the existence of such a description of gravity.Comment: 21 pages, some typos corrected and two references adde

Cooperation across Organizational Boundaries: Experimental Evidence from a Major Sustainability Science Project

Engaged research emphasizes researcher–stakeholder collaborations as means of improving the relevance of research outcomes and the chances for science-based decision-making. Sustainability science, as a form of engaged research, depends on the collaborative abilities and cooperative tendencies of researchers. We use an economic experiment to measure cooperation between university faculty, local citizens, and faculty engaged in a large sustainability science project to test a set of hypotheses: (1) faculty on the sustainability project will cooperate more with local residents than non-affiliated faculty, (2) sustainability faculty will have the highest level of internal cooperation of any group, and (3) that cooperation may vary due to academic training and culture in different departments amongst sustainability faculty. Our results demonstrate that affiliation with the sustainability project is not associated with differences in cooperation with local citizens or with in-group peers, but that disciplinary differences amongst sustainability faculty do correlate with cooperative tendencies within our sample. We also find that non-affiliated faculty cooperated less with each other than with faculty affiliated with the sustainability project. We conclude that economic experiments can be useful in discovering patterns of prosociality within institutional settings, and list challenges for further applications

A modified version of the BSID-II scales for cognitive matching of infants with and without Down syndrome

Background Many measures of infants’ early cognitive development, including the BSID-II, mix together test items that assess a number of different developmental domains including language, attention, motor functioning and social abilities, and some items contribute to the assessment of more than one domain. Consequently, the scales may lead to under- or over-estimates of cognitive abilities in some clinical samples and may not be the best measure to use for matching purposes. Method To address this issue we created a modified form of the BSID-II (the BSI-M) to provide a ‘purer’ assessment of the general cognitive capacities in infants with DS from 6 through to 18 months of age. We excluded a number of items that implicated language, motor, attentional and social functioning from the original measure. This modified form was administered to 17 infants with Down's syndrome when 6-, 12- and 18-months-old and to 41 typically developing infants at 4-, 7- and 10-months. Results The results suggested that the modified form continued to provide a meaningful and stable measure of cognitive functioning and revealed that DS infants may score marginally higher in terms of general cognitive abilities when using this modified form than they might when using the standard BSID-II scales. Conclusions This modified form may be useful for researchers who need a ‘purer’ measure with which to match infants with Down syndrome and other infants with IDs on cognitive functioning

Building resilience of coastal fishing communities to harmful algal blooms

Starting in May 2015 a massive harmful algal bloom (HAB) of the toxigenic diatom Pseudo-nitzschia occurred along the North American west coast resulting in unsafe levels of domoic acid in seafood. Subsequent fisheries harvest closures were both the longest and the most geographically widespread on record. Fishery-dependent coastal communities were severely impacted, with a fisheries resource disaster declaration occurring for the 2015-16 season of the California Dungeness crab fishery. This research aims to assess the social, cultural and economic impacts of the 2015 HAB event across 17 fishing communities on the US west coast using primary survey data. The survey instrument collected sociodemographic and economic factors hypothesized to confer resilience to HAB events as well as data that quantifies individual impacts. Community responses to the massive 2015 US west coast HAB event will be examined within a community disaster resilience framework. The impacts may be influenced by the community’s social vulnerability, dependence on commercial and recreational fisheries, as well as any immediate adaptive responses. The survey data will be used to empirically test existing indices of community social vulnerability and commercial fishing dependence that have been developed by NOAA using secondary data. The results from this analysis will identify protective factors that contribute to a community’s ability to cope with HABs, and promote cost-effective and practical means of building resilience to future HAB events in at-risk communities

Cognitive and social factors in the development of infants with Down syndrome

Infants and young children with Down syndrome can be engaging and affectionate. It seems that in the early months of life their personal relations may be relatively 'spared' the effects of limitations in their capacities for information-processing. Yet how far is this the case as development proceeds? In this paper we discuss some ways in which social and cognitive development interact and mutually influence one another over the first year or so of life, and present preliminary findings from a longitudinal study of infants with and without Down syndrome. The evidence suggests that the development of 'triadic'(person-person-world) social interactions may be affected by limited information-processing capacities in infants with Down syndrome, through a complex socially-mediated developmental trajectory

Electrically Charged Sphalerons

We investigate the possibility that the Higgs sector of the Weinberg-Salam model admits the existence of electrically charged, sphaleron states. Evidence is provided through an asymptotic and numerical perturbative analysis about the uncharged sphaleron. By introducing a toy model in two dimensions we demonstrate that such electrically charged, unstable states can exist. Crucially, they can have a comparable mass to their uncharged counterparts and so may also play a role in electroweak baryogenesis, by opening up new channels for baryon number violating processes.Comment: 12 pages, 4 Postscript figure

HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia.

IntroductionPneumonia is an important cause of morbidity and mortality in persons living with human immunodeficiency virus (HIV) infection. How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.MethodsThe Inflammation, Aging, Microbes, and Obstructive Lung Disease (I AM OLD) Cohort is a prospective cohort of adults with pneumonia in Uganda. In this cross-sectional analysis, plasma was collected at pneumonia presentation to measure the following 12 biomarkers: interleukin 6 (IL-6), soluble tumor necrosis factor receptors 1 and 2 (sTNFR-1 and sTNFR-2), high sensitivity C-reactive protein (hsCRP), fibrinogen, D-dimer, soluble CD27 (sCD27), interferon gamma-inducible protein 10 (IP-10), soluble CD14 (sCD14), soluble CD163 (sCD163), hyaluronan, and intestinal fatty acid binding protein. We asked whether biomarker levels differed between HIV-infected and HIV-uninfected participants, and whether higher levels of these biomarkers were associated with mortality.ResultsOne hundred seventy-three participants were enrolled. Fifty-three percent were HIV-infected. Eight plasma biomarkers-sTNFR-1, sTNFR-2, hsCRP, D-dimer, sCD27, IP-10, sCD14, and hyaluronan-were higher among participants with HIV infection, after adjustment for pneumonia severity. Higher levels of 8 biomarkers-IL-6, sTNFR-1, sTNFR-2, hsCRP, IP-10, sCD14, sCD163, and hyaluronan-were associated with increased 2-month mortality.ConclusionsAs in other clinical contexts, HIV infection is associated with a greater degree of immune activation among Ugandan adults with pneumonia. Some of these are also associated with short-term mortality. Further study is needed to explore whether these biomarkers might predict poor long-term outcomes-such as the development of obstructive lung disease-in patients with HIV who have recovered from pneumonia

Behaviour of infants with Down syndrome and their mothers in the still-face procedure

There has been limited study of how the constitutional characteristics of infants with Down syndrome (DS) influence the patterning of their relations with caregivers. To assess natural and perturbed interactions between infants with DS and their mothers, we tested ten 6-month-old infants with DS and 20 typically developing (TD) 4-month-old of similar mental age. Participants were videotaped with their mothers in a natural face-to-face interaction, a brief period when the mothers adopted a still-face, and a subsequent reengagement phase. There was little to distinguish the infants in the initial phase of natural interaction, but the mothers of infants with DS were more likely to show assertive warmth, and unlike in the case of mothers of TD infants, high maternal directiveness tended to be associated with lower levels of infant looking and lack of fussing. During the still-face episode, infants of both groups showed reduced looking and smiling, although infants with DS tended to show lower levels of fussing and fewer in this group showed fussing in the reengagement phase. Therefore DS infants were somewhat similar to TD infants of comparable mental age in being responsive to the still-face procedure, but showed indications of group differences in intense emotional reactivity

Pathogens, disease, and the social-ecological resilience of protected areas

It is extremely important for biodiversity conservation that protected areas are resilient to a range of potential future perturbations. One of the least studied influences on protected area resilience is that of disease. We argue that wildlife disease (1) is a social-ecological problem that must be approached from an interdisciplinary perspective; (2) has the potential to lead to changes in the identity of protected areas, possibly transforming them; and (3) interacts with conservation both directly (via impacts on wild animals, livestock, and people) and indirectly (via the public, conservation management, and veterinary responses). We use southern African protected areas as a case study to test a framework for exploring the connections between conservation, endemic disease, and social-ecological resilience. We first define a set of criteria for the social-ecological identity of protected areas. We then use these criteria to explore the potential impacts of selected diseases (foot-and-mouth disease, anthrax, malaria, rabies, rift valley fever, trypanosomiasis, and canine distemper) on protected area resilience. Although endemic diseases may have a number of direct impacts on both wild animals and domestic animals and people, the indirect pathways by which diseases influence social-ecological resilience also emerge as potentially important. The majority of endemic pathogens found in protected areas do not kill large numbers of wild animals or infect many people, and may even play valuable ecological roles; but occasional disease outbreaks and mortalities can have a large impact on public perceptions and disease management, potentially making protected areas unviable in one or more of their stated aims. Neighboring landowners also have a significant impact on park management decisions. The indirect effects triggered by disease in the human social and economic components of protected areas and surrounding landscapes may ultimately have a greater influence on protected area resilience than the direct ecological perturbations caused by disease