The use of pure carbon for permanent percutaneous electrical connector systems

Pure carbon was used as an electrode in the clinical application of long-term neuromuscular stimulation, as well as a connector for permanent neuroelectrodes. The history of this material and some examples of the material in use are presented

Photoluminescence rings in Corbino disk at quantizing magnetic fields

Spatially resolved photoluminescence of modulation doped AlGaAs/GaAs heterojunction was investigated in a sample of Corbino disk geometry subject to strong perpendicular magnetic fields. Significant spatial modulation of the photoluminescence was observed in form of one or more concentric rings which travelled across the sample when the magnetic field strength was varied. A topology of the observed structure excludes the possibility of being a trace of an external current. The effect is attributed to formation of compressible and incompressible stripes in a 2DEG density gradient across the sample.Comment: 5 two-column pages, 4 figures (one of them in color

Interferometric Mapping of Magnetic fields: NGC2071IR

We present polarization maps of NGC2071IR from thermal dust emission at 1.3 mm and from CO J=$2 \to 1$ line emission. The observations were obtained using the Berkeley-Illinois-Maryland Association array in the period 2002-2004. We detected dust and line polarized emission from NGC2071IR that we used to constrain the morphology of the magnetic field. From CO J=$2 \to 1$ polarized emission we found evidence for a magnetic field in the powerful bipolar outflow present in this region. We calculated a visual extinction $A_{\rm{v}} \approx 26$ mag from our dust observations. This result, when compared with early single dish work, seems to show that dust grains emit polarized radiation efficiently at higher densities than previously thought. Mechanical alignment by the outflow is proposed to explain the polarization pattern observed in NGC2071IR, which is consistent with the observed flattening in this source.Comment: 17 pages, 4 Figures, Accepted for publication in Ap

Has the experience of Hepatitis C diagnosis improved over the last decade? An analysis of Canadian women's experiences of diagnosis

Background In Canada, incidents of new hepatitis C virus infections are rising among women aged 15–29 years and now comprise 60% of new infections among this age group. A negative diagnosis experience continues to be a problem affecting women living with hepatitis C virus. With new effective treatments, nurses will have more involvement in hepatitis C virus care and diagnosis, which is a critical time to facilitate appropriate education and management. Purpose This study explored Canadian women’s experience of hepatitis C virus diagnosis in order to develop recommendations to improve care at the point of diagnosis. Methods Purposive sampling was used to recruit and interview 25 women. Using narrative inquiry, we examined Canadian women’s experience of hepatitis C virus diagnosis. Results Women’s diagnosis experiences were shaped by the context of diagnosis, factors prompting the testing, the testing provider, and information/education received. The context of diagnosis foreshadowed how prepared women were for their results, and the absence of accurate information magnified the psychological distress that can follow an hepatitis C virus diagnosis. Conclusion Our findings provide a compelling case for a proactive nursing response, which will improve women’s experiences of hepatitis C virus diagnosis and, in turn, enhance women’s access to hepatitis C virus care and other healthcare services

Functional specialization of transcription elongation factors

Elongation factors NusG and RfaH evolved from a common ancestor and utilize the same binding site on RNA polymerase (RNAP) to modulate transcription. However, although NusG associates with RNAP transcribing most Escherichia coli genes, RfaH regulates just a few operons containing ops, a DNA sequence that mediates RfaH recruitment. Here, we describe the mechanism by which this specificity is maintained. We observe that RfaH action is indeed restricted to those several operons that are devoid of NusG in vivo. We also show that RfaH and NusG compete for their effects on transcript elongation and termination in vitro. Our data argue that RfaH recognizes its DNA target even in the presence of NusG. Once recruited, RfaH remains stably associated with RNAP, thereby precluding NusG binding. We envision a pathway by which a specialized regulator has evolved in the background of its ubiquitous paralogue. We propose that RfaH and NusG may have opposite regulatory functions: although NusG appears to function in concert with Rho, RfaH inhibits Rho action and activates the expression of poorly translated, frequently foreign genes

Identifying success factors in crowdsourced geographic information use in government

Crowdsourcing geographic information in government is focusing on projects that are engaging people who are not government officials and employees in collecting, editing and sharing information with governmental bodies. This type of projects emerged in the past decade, due to technological and societal changes - such as the increased use of smartphones, combined with growing levels of education and technical abilities to use them by citizens. They also flourished due to the need for updated data in relatively quick time when financial resources are low. They range from recording the experience of feeling an earthquake to recording the location of businesses during the summer time. 50 cases of projects in which crowdsourced geographic information was used by governmental bodies across the world are analysed. About 60% of the cases were examined in 2014 and in 2017, to allow for comparison and identification of success and failure. The analysis looked at different aspects and their relationship to success: the drivers to start a project; scope and aims; stakeholders and relationships; inputs into the project; technical and organisational aspect; and problems encountered. The main key factors of the case studies were analysed with the use of Qualitative Comparative Analysis (QCA) which is an analytical method that combines quantitative and qualitative tools in sociological research. From the analysis, we can conclude that there is no “magic bullet” or a perfect methodology for a successful crowdsourcing in government project. Unless the organisation has reached maturity in the area of crowdsourcing, identifying a champion and starting a project that will not address authoritative datasets directly is a good way to ensure early success and start the process of organisational learning on how to run such projects. Governmental support and trust is undisputed. If the choice is to use new technologies, this should be accompanied by an investment of appropriate resources within the organisation to ensure that the investment bear fruits. Alternatively, using an existing technology that was successful elsewhere and investing in training and capacity building is another path for success. We also identified the importance of intermediary Non-Governmental Organizations (NGOs) with the experience and knowledge in working with crowdsourcing within a partnership. These organizations have the knowledge and skills to implement projects at the boundary between government and the crowd, and therefore can offer the experience to ensure better implementation. Changes and improvement of public services, or a focus on environmental monitoring can be a good basis for a project. Capturing base mapping is a good point to start, too. The recommendation of the report address organisational issues, resources, and legal aspects