Improvement of marketing communications methods and strategy of the building decoration industry enterprises in China

This work takes China Construction Oriental Decoration Co., Ltd. as an example to conduct targeted research, provides rationalized suggestions for the company's development, formulates marketing strategies, and helps company to achieve long-term healthy development goals. With the changes in the market situation, problems such as outdated business model, low resource concentration and imperfect pricing mechanism of the company began to appear, which seriously hindered the future development of the company. Through the analysis of the current situation and internal and external environment of China Construction Oriental Decoration Co., Ltd., this paper summarizes the company's existing problems in marketing, formulates a marketing strategy that meets its future development needs, and implements safeguards such as strengthening corporate culture construction

The impact of controlled ovarian stimulation hormones on the metabolic state and endocannabinoid system of human cumulus cells

Different Follicle Stimulating Hormone (FSH) formulation and Luteinizing Hormone (LH) are used in Assisted Reproductive Technology (ART) to induce follicles development and oocytes maturation, but it is still under debate which protocol is to be preferred. In the present study, the different effects on cumulus cells (CCs) of three controlled ovarian stimulation (COS) protocols, based on urinary FSH, recombinant FSH, or human Menopausal Gonadotropin (hMG) administration, were assessed. CCs were obtained from 42 normal-responders women undergoing COS, randomly divided into three groups according to the used gonadotropin formulation. Differences were found in the expression of genes belonging to the endocannabinoid system (the receptors CNR1, CNR2 and TRPV1, and the enzymes involved in the metabolisms of anandamide, NAPE-PLD and FAAH, and 2-acylglycerol, DAGL and MAGL); consistently, changes in lipid (PPARα, and FASN) and carbohydrate (GLUT1 and GLUT9) metabolisms, in CCs’ macromolecules composition (highlighted by Fourier Transform Infrared Microspectroscopy, FTIRM), and in the number of retrieved oocytes were found. For the first time, statistically significant evidence on the differences related to each COS protocol on the endocannabinoid system, metabolism and macromolecular composition of CCs was found, representing a proof of concept to be further confirmed in a larger cohort of patients

Does previous surgery influence the asymmetric distribution of endometriotic lesions?

Our objective was to investigate the role of previous abdominal-pelvic surgery in the asymmetric distribution of pelvic endometriosic lesions. This was a retrospective study carried out at the Clinic of Obstetrics and Gynecology, University of Ancona, Italy, and included 238 patients with histological confirmation of endometriosis. The interventions were surgical treatment, at laparoscopy or laparotomy, for pelvic pain and endometriosis. The main outcome measure(s) were endometriotic lesions and adhesions in the pelvis found during surgery and the dinical records of the patients. We found unilateral lesions in 149 patients (62.6%): the right side of the pelvis affected in 55 patients (36.9%) and the left side in 94 patients (63.1%) (p < 0.01). In the group of patients who had undergone previous abdominal surgery, we found lesions on the right side in 26 cases (32.5%), and on the left in 54 cases (67.5%) (p < 0.01). We found that the patients who had undergone previous abdominal surgery had significantly more adhesions than those with no previous surgery (80/116 vs. 73/122, p = 0. 002). As a new finding, we have demonstrated that the left side of asymmetric distribution of intrapelvic macroscopic lesions is preserved and more evident in patients with previous abdominal surgery, including previous appendectomy. These data seem to be in agreement with our previous supposition of a possible interaction between previous abdominal surgery and the mechanisms of endometriosis development

MODERNIZATION OF LUENBERGER OBSERVER FOR CONTROL SYSTEM OF HERMETIC COMPRESSOR ELECTRIC DRIVE

Context. The analysis of existing systems of sensorless control of hermetic compressor electric drives is carried out. The main requirements for control systems of automated electric drives of small refrigerating units’ hermetic compressorsare determined. The topology of the adaptive Luenberger observer, which allows real-time estimation of the current value of the rotational speed and load torque on the shaft of the hermetic compressor electric motor, is proposed.Objective. The object of the study is the coordinates observer as a part of control system of the hermetic compressor electric drive. The purpose of the work is to develop a mathematical model of the coordinates observer as a part of controlsystem of the hermetic compressor electric drive.Method. Based on the linearized model of a three-phase induction motor, the Luenberger observer is synthesized by the modal method with the distribution of the roots of the characteristic polynomial according to the standard linearBessel form.Results. The characteristic polynomial of the observer is obtained and the coefficients of the Luenberger matrix and the mean geometric root of the characteristic polynomial are calculated. To ensure the necessary accuracy the structure of the observer on the basis of the complete mathematical model of a three-phase induction motor executed in the fixed coordinate system is proposed. In the Matlab/Simulink simulation environment an imitation model of the Luenberger observer, which includes a complete mathematical model of the hermetic compressor electric motor in the fixed coordinate system, is constructed. By means of simulation modeling the work of the projected Luenberger observer is studied using the example of the modernized three-phase induction motor of the domestic refrigerator’s hermetic compressor.                                      Conclusions. The efficiency of the proposed method for identifying the rotational speed and the load torque of the compressor motor by the adaptive observer based on the calculation of the motor’s electromagnetic moment from themeasured data of the phase voltage and current sensors is confirmed. The error of the researching observer does not exceed 0.5% at the rotation speed and 10% at the load torque. The obtained structure of the adaptive Luenberger observermakes it possible to build closed control systems for the electric drive of a small refrigerating unit’s hermetic compressor

Uterine Fibroids: Pathogenesis and Interactions with Endometrium and Endomyometrial Junction.

Uterine leiomyomas (fibroids or myomas) are benign tumors of uterus and clinically apparent in a large part of reproductive aged women. Clinically, they present with a variety of symptoms: excessive menstrual bleeding, dysmenorrhoea and intermenstrual bleeding, chronic pelvic pain, and pressure symptoms such as a sensation of bloatedness, increased urinary frequency, and bowel disturbance. In addition, they may compromise reproductive functions, possibly contributing to subfertility, early pregnancy loss, and later pregnancy complications. Despite the prevalence of this condition, myoma research is underfunded compared to other nonmalignant diseases. To date, several pathogenetic factors such as genetics, microRNA, steroids, growth factors, cytokines, chemokines, and extracellular matrix components have been implicated in the development and growth of leiomyoma. This paper summarizes the available literature regarding the ultimate relative knowledge on pathogenesis of uterine fibroids and their interactions with endometrium and subendometrial myometrium

Uterine Fibroids: Pathogenesis and Interactions with Endometrium and Endomyometrial Junction.

Uterine leiomyomas (fibroids or myomas) are benign tumors of uterus and clinically apparent in a large part of reproductive aged women. Clinically, they present with a variety of symptoms: excessive menstrual bleeding, dysmenorrhoea and intermenstrual bleeding, chronic pelvic pain, and pressure symptoms such as a sensation of bloatedness, increased urinary frequency, and bowel disturbance. In addition, they may compromise reproductive functions, possibly contributing to subfertility, early pregnancy loss, and later pregnancy complications. Despite the prevalence of this condition, myoma research is underfunded compared to other nonmalignant diseases. To date, several pathogenetic factors such as genetics, microRNA, steroids, growth factors, cytokines, chemokines, and extracellular matrix components have been implicated in the development and growth of leiomyoma. This paper summarizes the available literature regarding the ultimate relative knowledge on pathogenesis of uterine fibroids and their interactions with endometrium and subendometrial myometrium

Transvaginal ultrasound assessment of urinary tract in gynecological oncology patients: A multicenter prospective study

Introduction: The aim of this study was to assess the prevalence of urinary tract involvement diagnosed on transvaginal ultrasound examination in women gynecological cancers. The diagnostic performance of transvaginal ultrasound in detecting ureteral and bladder involvement was also evaluated. Methods: This is a multicenter prospective study. Women with gynecological cancers or recurrence undergoing ultrasound examination were included. Transvaginal ultrasound is simple and non-invasive method. Ureters, vesico-uterine septum, bladder involvement were evaluated. Sensitivity, specificity, positive predictive values (PPV), negative predictive value (NPV) of ultrasound were calculated. Surgery or imaging methods (MRI or CT scan) were considered as reference standard. Results: A total of 569 patients were enrolled and 547 of them had diagnosis of malignancy. 56/547 (10.2%) had a diagnosis of urinary tract infiltration at ultrasound examination. On ultrasound examination, both ureters were clearly visualized in the vast majority of cases (507/547, 92.7%), whereas only one ureter was identified in 21/547 (3.8%) patients and both ureters were not visualized in 19/547 (3.5%). Ultrasound examination demonstrated high specificity (>99.0%) and high NPV (>97.0%) for all ultrasound parameters; sensitivity was good for bladder wall infiltration (83.3%) and for vesico-uterine septum infiltration (80.8%), and low for right (69.23%) and left (65.4%) ureter infiltration. Conclusions: The prevalence of pelvic urinary tract infiltration on transvaginal ultrasound examination in women with gynecologic malignancy was 10%. We believe that pelvic urinary tract assessment plays a key role during transvaginal ultrasound examination, in order to plan the management of patients with gynecologic cancers