Effects of Liposomes Contained in Thermosensitive Hydrogels as Biomaterials Useful in Neural Tissue Engineering

Indexación: Scopus.Advances in the generation of suitable thermosensitive hydrogels for the delivery of cells in neural tissue engineering demonstrate a delicate relationship between physical properties and capabilities to promote cell proliferation and differentiation. To improve the properties of these materials, it is possible to add liposomes for the controlled release of bioactive elements, which in turn can affect the physical and biological properties of the hydrogels. In the present investigation, different hydrogels based on Pluronic F127 have been formulated with the incorporation of chitosan and two types of liposomes of two different sizes. The rheological and thermal properties and their relation with the neurite proliferation and growth of the PC12 cell line were evaluated. Our results show that the incorporation of liposomes modifies the properties of the hydrogels dependent on the concentration of chitosan and the lipid type in the liposomes, which directly affect the capabilities of the hydrogels to promote the viability and differentiation of PC12 cells. © 2017 by the authors.http://www.mdpi.com/1996-1944/10/10/112

Chemistry in isolation: High CCH/HCO+ line ratio in the AMIGA galaxy CIG 638

Multi-molecule observations towards an increasing variety of galaxies have been showing that the relative molecular abundances are affected by the type of activity. However, these studies are biased towards bright active galaxies, which are typically in interaction. We study the molecular composition of one of the most isolated galaxies in the local Universe where the physical and chemical properties of their molecular clouds have been determined by intrinsic mechanisms. We present 3 mm broad band observations of the galaxy CIG 638, extracted from the AMIGA sample of isolated galaxies. The emission of the J=1-0 transitions of CCH, HCN, HCO+, and HNC are detected. Integrated intensity ratios between these line are compared with similar observations from the literature towards active galaxies including starburst galaxies (SB), active galactic nuclei (AGN), luminous infrared galaxies (LIRG), and GMCs in M33. A significantly high ratio of CCH with respect to HCN, HCO+, and HNC is found towards CIG 638 when compared with all other galaxies where these species have been detected. This points to either an overabundance of CCH or to a relative lack of dense molecular gas as supported by the low HCN/CO ratio, or both. The data suggest that the CIG 638 is naturally a less perturbed galaxy where a lower fraction of dense molecular gas, as well as a more even distribution could explain the measured ratios. In this scenario the dense gas tracers would be naturally dimmer, while the UV enhanced CCH, would be overproduced in a less shielded medium.Comment: Letter accepted for publication in A&

Curvature and Acoustic Instabilities in Rotating Fluid Disks

The stability of a rotating fluid disk to the formation of spiral arms is studied in the tightwinding approximation in the linear regime. The dispersion relation for spirals that was derived by Bertin et al. is shown to contain a new, acoustic instability beyond the Lindblad resonances that depends only on pressure and rotation. In this regime, pressure and gravity exchange roles as drivers and inhibitors of spiral wave structures. Other instabilities that are enhanced by pressure are also found in the general dispersion relation by including higher order terms in the small parameter 1/kr for wavenumber k and radius r. These instabilities are present even for large values of Toomre's parameter Q. Unstable growth rates are determined in four cases: a self-gravitating disk with a flat rotation curve, a self-gravitating disk with solid body rotation, a non-self-gravitating disk with solid body rotation, and a non-self-gravitating disk with Keplerian rotation. The most important application appears to be as a source of spiral structure, possibly leading to accretion in non-self-gravitating disks, such as some galactic nuclear disks, disks around black holes, and proto-planetary disks. All of these examples have short orbital times so the unstable growth time can be small.Comment: 30 pages, 5 figures, scheduled for ApJ 520, August 1, 199

A ~ 12 kpc HI extension and other HI asymmetries in the isolated galaxy CIG 340 (IC 2487)

HI kinematic asymmetries are common in late-type galaxies irrespective of environment, although the amplitudes are strikingly low in isolated galaxies. As part of our studies of the HI morphology and kinematics in isolated late-type galaxies we have chosen several very isolated galaxies from the AMIGA sample for HI mapping. Here we present GMRT 21-cm HI line mapping of CIG 340 which was selected because its integrated HI spectrum has a very symmetric profile, Aflux = 1.03. Optical images of the galaxy hinted at a warped disk in contrast to the symmetric integrated HI spectrum profile. Our aim is to determine the extent to which the optical asymmetry is reflected in the resolved HI morphology and kinematics. GMRT observations reveal significant HI morphological asymmetries in CIG 340 despite it's overall symmetric optical form and highly symmetric HI spectrum. The most notable HI features are: 1) a warp in the HI disk (with an optical counterpart), 2) the HI north/south flux ratio = 1.32 is much larger than expected from the integrated HI spectrum profile and 3) a ~ 45" (12 kpc) HI extension, containing ~ 6% of the detected HI mass on the northern side of the disk. We conclude that in isolated galaxies a highly symmetric HI spectrum can mask significant HI morphological asymmetries. The northern HI extension appears to be the result of a recent perturbation (10^8 yr), possibly by a satellite which is now disrupted or projected within the disk. This study provides an important step in our ongoing program to determine the predominant source of HI asymmetries in isolated galaxies. For CIG 340 the isolation from major companions, symmetric HI spectrum, optical morphology and interaction timescales have allowed us to narrow the possible causes the HI asymmetries and identify tests to further constrain the source of the asymmetries.Comment: 10 page

Fingerprinting the magnetic behavior of antiferromagnetic nanostructures using remanent magnetization curves

Antiferromagnetic (AF) nanostructures from Co3O4, CoO and Cr2O3 were prepared by the nanocasting method and were characterized magnetometrically. The field and temperature dependent magnetization data suggests that the nanostructures consist of a core-shell structure. The core behaves as a regular antiferromagnet and the shell as a two-dimensional diluted antiferromagnet in a field (2d DAFF) as previously shown on Co3O4 nanowires [Benitez et al., Phys. Rev. Lett. 101, 097206 (2008)]. Here we present a more general picture on three different material systems, i.e. Co3O4, CoO and Cr2O3. In particular we consider the thermoremanent (TRM) and the isothermoremanent (IRM) magnetization curves as "fingerprints" in order to identify the irreversible magnetization contribution originating from the shells. The TRM/IRM fingerprints are compared to those of superparamagnetic systems, superspin glasses and 3d DAFFs. We demonstrate that TRM/IRM vs. H plots are generally useful fingerprints to identify irreversible magnetization contributions encountered in particular in nanomagnets.Comment: submitted to PR

Galaxy Interactions in Compact Groups II: abundance and kinematic anomalies in HCG 91c

Galaxies in Hickson Compact Group 91 (HCG 91) were observed with the WiFeS integral field spectrograph as part of our ongoing campaign targeting the ionized gas physics and kinematics inside star forming members of compact groups. Here, we report the discovery of HII regions with abundance and kinematic offsets in the otherwise unremarkable star forming spiral HCG 91c. The optical emission line analysis of this galaxy reveals that at least three HII regions harbor an oxygen abundance ~0.15 dex lower than expected from their immediate surroundings and from the abundance gradient present in the inner regions of HCG 91c. The same star forming regions are also associated with a small kinematic offset in the form of a lag of 5-10 km/s with respect to the local circular rotation of the gas. HI observations of HCG 91 from the Very Large Array and broadband optical images from Pan-STARRS suggest that HCG 91c is caught early in its interaction with the other members of HCG 91. We discuss different scenarios to explain the origin of the peculiar star forming regions detected with WiFeS, and show that evidence point towards infalling and collapsing extra-planar gas clouds at the disk-halo interface, possibly as a consequence of long-range gravitational perturbations of HCG 91c from the other group members. As such, HCG 91c provides evidence that some of the perturbations possibly associated with the early phase of galaxy evolution in compact groups impact the star forming disk locally, and on sub-kpc scales.Comment: 25 pages, 21 figures, MNRAS accepted. Until publication of the article, the interactive component of Figure 4 is available at this URL: http://www.mso.anu.edu.au/~fvogt/website/misc.htm

Sensitive VLBI Continuum and H I Absorption Observations of NGC 7674: First Scientific Observations with the Combined Array VLBA, VLA & Arecibo

We present phase-referenced VLBI observations of the radio continuum emission from, and the H I 21 cm absorption toward, the Luminous Infrared Galaxy NGC 7674. The observations were carried out at 1380 MHz using the VLBA, the phased VLA, and theArecibo radio telescope. These observations constitute the first scientific use of the Arecibo telescope in a VLBI observation with the VLBA. The high- and low-resolution radio continuum images reveal several new continuum structures in the nuclear region of this galaxy. At ~100 mas resolution, we distinguish six continuum structures extending over 1.4 arcsec, with a total flux density of 138 mJy. Only three of these structures were known previously. All these structures seem to be related to AGN activity. At the full resolution of the array, we only detect two of the six continuum structures. Both are composed of several compact components with brightness temperatures on the order of $10^{7}$ K. While it is possible that one of these compact structures could host an AGN, they could also be shock-like features formed by the interaction of the jet with compact interstellar clouds in the nuclear region of this galaxy. Complex H I absorption is detected with our VLBI array at both high and low angular resolution. Assuming that the widest H I feature is associated with a rotating H I disk or torus feeding a central AGN, we estimate an enclosed dynamical mass of ~7 x 10^7 M_sun, comparable to the value derived from the hidden broad H$\beta$ emission in this galaxy. The narrower H I lines could represent clumpy neutral hydrogen structures in the H I torus. The detection of H I absorption toward some of the continuum components, and its absence toward others, suggest an inclined H I disk or torus in the central region of NGC 7674.Comment: 37 pages, 11 figures. ApJ accepted. To appear in the Nov. 10, 2003 issue of ApJ. Please use the PDF version if the postscript doesn't show the figure

Dynamical effects of interactions and the Tully-Fisher relation for Hickson compact groups

We investigate the properties of the B-band Tully-Fisher (T-F) relation for 25 compact group galaxies, using Vmax derived from 2-D velocity maps. Our main result is that the majority of the Hickson Compact Group galaxies lie on the T-F relation. However, about 20% of the galaxies, including the lowest-mass systems, have higher B luminosities for a given mass, or alternatively, a mass which is too low for their luminosities. We favour a scenario in which outliers have been brightened due to either enhanced star formation or merging. Alternatively, the T-F outliers may have undergone truncation of their dark halo due to interactions. It is possible that in some cases, both effects contribute. The fact that the B-band T-F relation is similar for compact group and field galaxies tells us that these galaxies show common mass-to-size relations and that the halos of compact group galaxies have not been significantly stripped inside R25. We find that 75% of the compact group galaxies studied (22 out of 29) have highly peculiar velocity fields. Nevertheless, a careful choice of inclination, position angle and center, obtained from the velocity field, and an average of the velocities over a large sector of the galaxy enabled the determination of fairly well-behaved rotation curves for the galaxies. However, two of the compact group galaxies which are the most massive members in M51--like pairs, HCG 91a and HCG 96a, have very asymmetric rotation curves, with one arm rising and the other one falling, indicating, most probably, a recent perturbation by the small close companions.Comment: 15 pages, 4 figures, accepted for publication in the Astronomical Journa