J.-P. Boutinet, N. Denoyel, G. Pineau, & J.-Y. Robin. (dir.). Penser l’accompagnement adulte

Publié sous la direction de J-P Boutinet, N. Denoyel, G. Pineau et J.-Y. Robin, Penser l’accompagnement adulte correspond à la suite (et non aux actes) du colloque international qui s’est tenu en mai 2003 sur le thème de « l’accompagnement et ses paradoxes ». Depuis, l’actualité autour de ce sujet n’a pas faibli et les auteurs ont souhaité faire le point sur les pratiques d'accompagnement et les façons dont elles sont théorisées dans le but de fournir des éléments de réponse destinés à mieux ..

J.-P. Boutinet, N. Denoyel, G. Pineau, & J.-Y. Robin. (dir.). Penser l’accompagnement adulte

Publié sous la direction de J-P Boutinet, N. Denoyel, G. Pineau et J.-Y. Robin, Penser l’accompagnement adulte correspond à la suite (et non aux actes) du colloque international qui s’est tenu en mai 2003 sur le thème de « l’accompagnement et ses paradoxes ». Depuis, l’actualité autour de ce sujet n’a pas faibli et les auteurs ont souhaité faire le point sur les pratiques d'accompagnement et les façons dont elles sont théorisées dans le but de fournir des éléments de réponse destinés à mieux ..

Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences.

Abstract: A novel property of DNA is described: the capacity of some bacterial DNA sequences to induce electromagnetic waves at high aqueous dilutions. It appears to be a resonance phenomenon triggered by the ambient electromagnetic background of very low frequency waves. The genomic DNA of most pathogenic bacteria contains sequences which are able to generate such signals. This opens the way to the development of highly sensitive detection system for chronic bacterial infections in human and animal diseases

Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences.

Abstract: A novel property of DNA is described: the capacity of some bacterial DNA sequences to induce electromagnetic waves at high aqueous dilutions. It appears to be a resonance phenomenon triggered by the ambient electromagnetic background of very low frequency waves. The genomic DNA of most pathogenic bacteria contains sequences which are able to generate such signals. This opens the way to the development of highly sensitive detection system for chronic bacterial infections in human and animal diseases

0107: Strategy of early detection and active management of supraventricular arrhythmia with remote monitoring: the randomized, multicenter SETAM trial

ObjectiveAtrial fibrillation (AF) is a common arrhythmia associated with increased risk of thromboembolic events or other complications. The French randomized, multicenter, SETAM trial assessed the impact of the home monitoring (HM) technology on detection and treatment of supra-ventricular arrhythmia (SVA).MethodsPatients (pts) implanted with a dual chamber pacemaker were enrolled in the study at hospital discharge if they had a sinusal rhythm at enrollment, no antiarrhythmic, anticoagulant or dual-antiplatelet therapy, and if they had a CHA2DS2-VASc score of 2 or more. The pts were randomly assigned to an active group (Act Gp), followed by Biotronik HM, or a control group (Cont Gp) without HM surveillance. The time from implantation to the first SVA-related intervention was compared between the 2 groups (primary endpoint).ResultsA total of 595 pts (mean age = 79±8 y.o, 63% male, mean CHA2DS2-VASc score = 3.7±1.2) were followed during 12.8±3.3Mo. The most prevalent co-morbidities were hypertension (82% pts), diabetes (29%) and vascular disease (24%). Implantation indications were atrio-ventricular blocks in 77% of pts, sinus node disease in 20% and others in 3%.The global SVA incidence was 25% (29% in the Act Gp vs 22% in the Cont Gp, p=ns).A therapy (drugs or ablation) was instituted for 49/291 pts (17%) in the Act Gp vs 43/304 pts (14%) in the Cont Gp (p=ns). The median time from implantation to the first therapy for SVA was 114 [44; 241] days in the Act Gp vs 224 [67; 366] days in the Cont Gp, representing a median gain of 110-days in SVA management (50% reduction, p=0.01). Over these 92 pts, 54 had AF (59%) and 38 had atrial flutter or tachyarrhythmia (41%). Anticoagulation was initiated in 80% of pts and antiarrhythmic drugs in 55%.ConclusionThe SETAM study demonstrated that HM allows earlier detection and treatment of SVA in pacemaker pts. The next step is to report how early detection of SVA with HM can possibly improve the patients clinical outcome

Detection and characterisation of 54 massive companions with the SOPHIE spectrograph Seven new brown dwarfs and constraints on the brown dwarf desert

Context. Brown dwarfs (BD) are substellar objects intermediate between planets and stars with masses of ~13–80 MJ. While isolated BDs are most likely produced by gravitational collapse in molecular clouds down to masses of a few MJ, a non-negligible fraction of low-mass companions might be formed through the planet-formation channel in protoplanetary discs. The upper mass limit of objects formed within discs is still observationally unknown, the main reason being the strong dearth of BD companions at orbital periods shorter than 10 yr, also known as the BD desert. Aims. To address this question, we aim at determining the best statistics of companions within the 10–100 MJ mass regime and located closer than ~10 au to the primary star, while minimising observation and selection bias. Methods. We made extensive use of the radial velocity (RV) surveys of northern hemisphere FGK stars within 60 pc of the Sun, performed with the SOPHIE spectrograph at the Observatoire de Haute-Provence. We derived the Keplerian solutions of the RV variations of 54 sources. Public astrometric data of the HIPPARCOS and Gaia missions allowed us to constrain the masses of the companions for most sources. We introduce GASTON, a new method to derive inclination combining RVs and Keplerian and astrometric excess noise from Gaia DR1. Results. We report the discovery of 12 new BD candidates. For five of them, additional astrometric data led to a revision of their mass in the M-dwarf regime. Among the seven remaining objects, four are confirmed BD companions, and three others are likely also in this mass regime. Moreover, we report the detection of 42 M-dwarfs within the range of 90 MJ–0.52 M⊙. The resulting M sin i-P distribution of BD candidates shows a clear drop in the detection rate below 80-day orbital period. Above that limit, the BD desert appears rather wet, with a uniform distribution of the M sin i. We derive a minimum BD-detection frequency around Solar-like stars of 2.0 ± 0.5%.ISSN:0004-6361ISSN:1432-074