3 research outputs found

    Modelación del riesgo de crédito para una caja de compensación familiar

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    En este trabajo se caracteriza el endeudamiento del sector de las familias con el sistema de crĂ©dito de las cajas de compensaciĂłn familiar durante el periodo de agosto de 2007, y se hallan los determinantes de la probabilidad de que una persona natural incumpla con el pago las obligaciones que ha contraĂ­do con esta. A travĂ©s de un modelo logit multinomial se encontrĂł que la probabilidad de incumplimiento estĂĄ asociada a caracterĂ­sticas tales como el plazo del crĂ©dito, la tasa de interĂ©s, el sexo, la antigĂŒedad laboral y la garantĂ­a que los individuos puedan aportar como respaldo de los crĂ©ditos. Las predicciones muestran que la probabilidad de incumplimiento se incrementa a medida que se presentan estas caracterĂ­sticas en los prĂ©stamos personales.72 p.Contenido parcial: Basilea II -- El riesgo de crĂ©dito segĂșn Basilea II -- Superintendencia financiera -- Marco teĂłrico y estado del arte -- EspecificaciĂłn del modelo de respuesta mĂșltiple ordenado -- Probabilidad de incumplimiento a partir de un modelo logit ordenado

    The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

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    International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population

    The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

    No full text
    International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population
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