Sustainable Retrofitting Solutions: Evaluating the Performance of Jute Fiber Nets and Composite Mortar in Natural Fiber Textile Reinforced Mortars

Sustainable building materials for integrated (structural and thermal) retrofitting are the need of the hour to retrofit/upgrade the seismic vulnerable and ill-insulated existing building stocks. At the same time, the use of natural fibers and their recyclability could help construct safer and more sustainable buildings. This paper presents three aspects of jute fiber products: (1) the evaluation of the mechanical performance of the jute nets (2.5 cm × 2.5 cm and 2.5 cm and 1.25 cm mesh configurations) through tensile strength tests (with the aim for these to be used in upgrading masonry wall with natural fiber textile reinforced mortars (NFTRM) systems); (2) the hundred percentage recyclability of left-over jute fibers (collected during the net fabrication and failed nets post-tensile strength tests) for the composite mortar preparation; (3) and the evaluation of insulation capacity of the recycled jute net fiber composite mortar (RJNFCM) through thermal conductivity (TC) measurements, when a maximum amount of 12.5% of recycled jute fiber could be added in the mortar mixture at laboratory conditions and with available instruments Notably, when more than the said amount was used, the fiber–mortar bonding was found to be not optimal for the composite mortar preparation. These studies have been carried out considering these products’ applicability for integrated retrofitting purposes. It has been found that the denser mesh configuration (2.5 cm × 1.25 cm) is 35.80% stiffer than the other net configurations (2.5 cm × 2.5 cm). Also, the mesh configuration (2.5 cm × 1.25 cm) shows about 60% more capability to absorb strain energy. TC tests have demonstrated the moderate insulation capacity of these composite mortar samples, and the TC values obtained from the tests range from 0.110 (W/mK) to 0.121 (W/mK)

Prediction of Building Limestone Physical and Mechanical Properties by Means of Ultrasonic P-Wave Velocity

The aim of this study was to evaluate ultrasonic P-wave velocity as a feature for predicting some physical and mechanical properties that describe the behavior of local building limestone. To this end, both ultrasonic testing and compressive tests were carried out on several limestone specimens and statistical correlation between ultrasonic velocity and density, compressive strength, and modulus of elasticity was studied. The effectiveness of ultrasonic velocity was evaluated by regression, with the aim of observing the coefficient of determination r2 between ultrasonic velocity and the aforementioned parameters, and the mathematical expressions of the correlations were found and discussed. The strong relations that were established between ultrasonic velocity and limestone properties indicate that these parameters can be reasonably estimated by means of this nondestructive parameter. This may be of great value in a preliminary phase of the diagnosis and inspection of stone masonry conditions, especially when the possibility of sampling material cores is reduced

A Prospective Evaluation of Point of Care Ultrasound Teaching in Switzerland.

ContextAs the utility of point-of-care ultrasound (POCUS) continues to expand in the medical field, there is a need for effective educational methods. In Switzerland, medical education follows the European model and lasts 6 years, focusing on preclinical training during the first 2 years. No previous studies have evaluated the optimal time for teaching ultrasound in European medical education.AimsThe aim of this study is to provide ultrasound training to medical students in Switzerland at varying times during their clinical training to determine if the level of training plays a role in their ability to comprehend and to apply basic POCUS skills.MethodsWe performed an observational study utilizing a convenience sample of Swiss medical students between July 11, 2016 and August 6, 2016. They were taught a 2-day POCUS course by five American-trained 1st-year medical students. Following this course, students were evaluated with written and clinical examination.Results100 Swiss medical students were enrolled in the study. A total of 59 of these students were early clinical students, and 41 students were late clinical students. A two-tailed t-test was performed and demonstrated that the late clinical students performed better than the early clinical students on the written assessment; however, no difference was found in clinical skill.ConclusionOur data suggest that Swiss medical students can learn and perform POCUS after a 2-day instructional taught by trained 1st-year American medical students. No difference was found between students in early clinical training and late clinical training for the ability to perform POCUS

AKT/mTOR Signaling Modulates Resistance to Endocrine Therapy and CDK4/6 Inhibition in Metastatic Breast Cancers

Endocrine therapy (ET) in combination with CDK4/6 inhibition is routinely used as first-line treatment for HR+/HER2− metastatic breast cancer (MBC) patients. However, 30–40% of patients quickly develop disease progression. In this open-label multicenter clinical trial, we utilized a hypothesis-driven protein/phosphoprotein-based approach to identify predictive markers of response to ET plus CDK4/6 inhibition in pre-treatment tissue biopsies. Pathway-centered signaling profiles were generated from microdissected tumor epithelia and surrounding stroma/immune cells using the reverse phase protein microarray. Phosphorylation levels of the CDK4/6 downstream substrates Rb (S780) and FoxM1 (T600) were higher in patients with progressive disease (PD) compared to responders (p = 0.02). Systemic PI3K/AKT/mTOR activation in tumor epithelia and stroma/immune cells was detected in patients with PD. This activation was not explained by underpinning genomic alterations alone. As the number of FDA-approved targeted compounds increases, functional protein-based signaling analyses may become a critical component of response prediction and treatment selection for MBC patients

Repensando el turismo sustentable

El libro aborda la problemática del turismo sustentable que, por un lado, al compartir contornos nebulosos con la sustentabilidad, funciona como un nuevo circuito de acumulación fundamentado en un discurso retórico de desarrollo local; por el otro, se nos presenta como una alternativa potencial para la formulación de vías comunitarias de desarrollo local, que permitirían la prosperidad o al menos la sobrevivencia de culturas y territorios partucularizados.Universidad Autónoma del Estado de Méxic

Gobiernos municipales y partidos políticos en el Estado de México

Se analiza el desempeño de los partidos Revolucionario Institucional, Acción Nacional, de la Revolución Democrática y del Trabajo al frente de doce municipios del Estado de México: Amecameca, Atlautla de Victoria, Chalco, Chimalhuacán, Huixquilucan, Ixtapan de la Sal, Naucalpan, Nezahualcóyotl, Ozumba, Tejupilco, Tepotzotlán y Tlalnepantla. El objetivo fue analizar tanto la gestión de gobierno como la influencia del partido en el municipio.Instituto Electoral del Estado de México Universidad Autónoma del Estado de Méxic