1,413 research outputs found

    Transformational government and assistive web base technologies

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    Transformational government has been on the European agenda for several years. However, progress towards realising the full potential of ICT to transform public services for older adults with age related cognitive impairments has been very limited. Highlighting such limitations this paper demonstrates how assistive web base technologies can be developed to improve the public services for older adults with age related cognitive impairments. However the paper argues that these transformations can be obstructed if there is no strong leadership and political commitment from people at many levels in public sectors and governments

    Thou Shalt Lie: Anticipatory Deflection Management

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    As people visualize ongoing or future interactions, do they lie to maintain situational congruency? While visualizing various behavioral options, or the outcomes of such behaviors, people have a unique opportunity to preemptively alter the definition of the situation based on anticipated sentiments. Affect Control Theory emphasizes the salience of deflection management in everyday life. This is otherwise known as an attempted realignment of experiences and expectations in the face of situational incongruency such as the bizarre. Using a vignette experiment, I extend Affect Control Theory by illuminating deflection not yet experienced but instead anticipated. I do so by estimating the odds of lying in an ongoing interaction where an honest retelling would incur high deflection. To further inform this cognitive process, I provide qualitative explanations from participants on why they chose their responses and how the dynamics of their relationship mattered, highlighting the underlying social and cognitive processes behind active decision making in ongoing interactions

    Black and Minority Ethnic Trainees' Experiences of Physical Education Initial Teacher Training: Report to the Training and Development Agency

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    The iconography of Asphyxiophilia: From fantasmatic fetish to forensic fact

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    This is a post print version of the article. The official published version can be accessed from the link below

    Affinity-based proteomics reveals novel binding partners for Rab46 in endothelial cells

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    Rab46 is a novel Ca2+-sensing Rab GTPase shown to have important functions in endothelial and immune cells. The presence of functional Ca2+-binding, coiled-coil and Rab domains suggest that Rab46 will be important for coupling rapid responses to signalling in many cell types. The molecular mechanisms underlying Rab46 function are currently unknown. Here we provide the first resource for studying Rab46 interacting proteins. Using liquid chromatography tandem mass spectrometry (LC–MS/MS) to identify affinity purified proteins that bind to constitutively active GFP-Rab46 or inactive GFP-Rab46 expressed in endothelial cells, we have revealed 922 peptides that interact with either the GTP-bound Rab46 or GDP-bound Rab46. To identify proteins that could be potential Rab46 effectors we performed further comparative analyses between nucleotide-locked Rab46 proteins and identified 29 candidate effector proteins. Importantly, through biochemical and imaging approaches we have validated two potential effector proteins; dynein and the Na2+/ K+ ATPase subunit alpha 1 (ATP1α1). Hence, our use of affinity purification and LC–MS/MS to identify Rab46 neighbouring proteins provides a valuable resource for detecting Rab46 effector proteins and analysing Rab46 functions

    Do educational experiences in school prepare students for university? A teachers’ perspective

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    Entering higher education is a critical moment for many students and one where their educational experiences may change dramatically, but are students academically prepared? From a structured and supported environment, they enter a more autonomous and independent setting and little is known about their preparedness for this transition. This paper explores, through the voices of teachers in schools and colleges, two aspects of preparedness for higher education, independent learning and academic confidence, in order to more closely examine the challenges faced by thousands of new students each year. The findings highlighted differences in both terminology and approach between the two educational layers and contributes new insights to support universities in enhancing practice through a deeper understanding of the prior experiences of their new students through the lens of their teachers. Overall the paper highlights some significant messages about the gap between these two levels of education which cannot simply be left to the student to navigate

    Small loans: credit unions' best-kept secret? An analysis of the economics and opportunity for credit unions serving the small loans market in Ireland

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    This report examine the small loans market (loans of less than €2,000) in the Republic of Ireland and the role of credit unions in serving this market. The report offers international comparisons, evaluates commercial viability, assesses the views of credit unions and stakeholders and offers recommendations. The research comprised interviews with credit unions and stakeholders in the Republic of Ireland, USA, Canada and Great Britain, a review of market data and literature, and economic analysis using CUFA Ltd dat
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