TRITEX : chromosome-scale sequence assembly of Triticeae genomes with open-source tools

Chromosome-scale genome sequence assemblies underpin pan-genomic studies. Recent genome assembly efforts in the large-genome Triticeae crops wheat and barley have relied on the commercial closed-source assembly algorithm DeNovoMagic. We present TRITEX, an open-source computational workflow that combines paired-end, mate-pair, 10X Genomics linked-read with chromosome conformation capture sequencing data to construct sequence scaffolds with megabase-scale contiguity ordered into chromosomal pseudomolecules. We evaluate the performance of TRITEX on publicly available sequence data of tetraploid wild emmer and hexaploid bread wheat, and construct an improved annotated reference genome sequence assembly of the barley cultivar Morex as a community resource.Peer reviewe

The Praeger Handbook on Stress and Coping

Edited by Alan Monat, Richard S. Lazarus, and Gretchen Reevy. Includes a chapter by former college at Brockport faculty member, David F. Duncan: Growing up under the gun : children and adolescents coping with violent neighborhoods. One of the most famed figures in the psychology field worldwide, the late Richard Lazarus worked with coeditors Alan Monat and Gretchen Reevy to fashion this anthology focused on one area of psychology nearly every person can relate to—stress. A team of researchers presents current and classic findings on the mental and physical effects of stress, as well as the means to manage and cope with everyday stress as well as extreme stress. Included are chapters by Lance Armstrong on coping with cancer and a chapter by Dean Ornish explaining how stress—self-imposed or not—affects the heart. Today factors ranging from war, terrorism, and disaster to discrimination, divorce, and daily job struggles make all of us painfully aware of stress. This set gives readers across backgrounds a solid introduction to classic and contemporary thought in a field so relevant to successful living. These volumes will also be of interest to researchers, students, and scholars in psychology, health science, psychiatry, nursing, and physical education.https://digitalcommons.brockport.edu/bookshelf/1258/thumbnail.jp

Solutions for construction of a lunar base: A proposal to use the spacex starship as a permanent habitat

International audienceReturning to the Moon and establishing a permanent human presence is the next step in human space exploration. This necessitates the development of lunar infrastructure up to this task. This contribution presents a framework for rapid, cost-efficient, and supporting construction of a permanent and modular lunar base within the scope of what will be technically and legally feasible today. The proposed concept uses the SpaceX Starship Human Landing System as the foundation for a lunar base. The Starship will be placed horizontally on the lunar surface and transformed into a habitable volume. A workforce of modular rovers will aid astronauts in the construction process, and an array of countermeasures are presented to protect the astronauts from the effects of exposure to radiation, lunar dust, and extended hypogravity. Psychological and psychosocial factors are included to enhance individual well-being and crew dynamics. Physical and cognitive workloads are defined and evaluated to identify effective countermeasures, including specific spacesuit requirements. The proposed construction activities are to be organized as a multi-national public-private partnership to establish an international authority, a concept that has been successful on Earth but has yet to be applied to space activities on a multi-national level. A roadmap incorporating each part of the construction from human and technical perspectives is outlined. Other aspects that are critical to mission success include the cultural significance of the project, legal aspects, budget, financing, and potential future uses of the base. These solutions rely mainly on existing technologies and limited modifications to the lunar lander vehicle, making it a viable solution for the construction of a lunar base in the near future