Alternative Extraction Systems for Precious Metals Recovery: Aqueous Biphasic Systems, Ionic Liquids, Deep Eutectic Solvents

The current trend in the development of separation methodologies implies their evolution in an environmentally friendly perspective, more precisely, the transition to techniques, materials, and solvents that could be qualified as greener alternatives to conventional ones. The green extraction systems can be attributed to aqueous biphasic systems, ionic liquids, and deep eutectic solvents, which have been widely used recently for various analytical, synthetic, and industrial tasks. In this chapter, the features of the listed systems are discussed in relation to the extraction of precious metals, mainly platinum, palladium, and gold; the examples of the alternative extraction systems for separation and preconcentration of precious metals are reviewed

Progress in Targeted Alpha-Particle Therapy. What We Learned about Recoils Release from In Vivo Generators

This review summarizes recent progress and developments as well as the most important pitfalls in targeted alpha-particle therapy, covering single alpha-particle emitters as well as in vivo alpha-particle generators. It discusses the production of radionuclides like 211At, 223Ra, 225Ac/213Bi, labelling and delivery employing various targeting vectors (small molecules, chelators for alpha-emitting nuclides and their biomolecular targets as well as nanocarriers), general radiopharmaceutical issues, preclinical studies, and clinical trials including the possibilities of therapy prognosis and follow-up imaging. Special attention is given to the nuclear recoil effect and its impacts on the possible use of alpha emitters for cancer treatment, proper dose estimation, and labelling chemistry. The most recent and important achievements in the development of alpha emitters carrying vectors for preclinical and clinical use are highlighted along with an outlook for future developments

Nanosized magnetite modified with poly(ethylene glycol) for efficient sorption of L-lysine-α-oxidase from the culture fluid

Fe3O4@PEG have been proposed for sorption of L-lysine-α-oxidase (LO) from the culture fluid of Trichoderma harzianum Rifai F-180 for the first time. To synthesize the Fe3O4@PEG nanoparticles, an original method based on aqueous biphasic systems has been developed. The PEG-modified magnetite provide a high sorption ability towards LO in contrast to the non-modified Fe3O4 synthesized by the traditional precipitation method. The morphology and structure of the prepared nanoparticles were characterized by TEM, FTIR and XRD. The data on magnetic properties and stability in physiological media are presented. The synthesized nanoparticles ensure quantitative sorption and desorption of LO during at least 3 cycles. © 2022 Elsevier B.V