From environmental protection to sustainable development and «green economy»: national project of education greening in Kazakhstan

The aim of the investigation is to show an education system role during transition to "green economy" – to a new stage of development of world economy.Methods. The methods involve the analysis and generalization of contents of the international and interstate documents of the Republic of Kazakhstan urged to provide sustainable social and economic development. Retrospective and project analysis of course processes features of social and economic system greening of Kazakhstan is also applied.Results and scientific novelty. The essence of the concepts «green economy», "ecological enlightenment", "ecological education" and "greening of society" are disclosed. The Kazakh national specifics of implementation of the international documents on implementation of model of a sustainable development are shown. The Concept of ecological formation of the Republic of Kazakhstan according to which the education system of the country is urged to create, develop and fix effectively, along with a necessary complex of knowledge, stereotypes of behavior of the people capable to make reasonable decisions is provided and to work according to legislatively consolidated nature protection regulations and standards. It is stated that greening of content of education in the republic has the developed regulatory framework, however additional measures for upgrade of an education system are necessary: its theoretical and methodological reasons, preparation and advanced training of pedagogical personnel, development of the new methodical means bring into focus an ecological orientation of training and education, etc.Practical significance. Measures for further improvement of ecological education and ecological education at all steps of education are listed. Цель статьи – продемонстрировать роль системы образования в период перехода к «зеленой экономике» – новому этапу развития мировых экономик. Методы. В процессе работы использовались анализ и обобщение содержания международных и внутригосударственных документов Республики Казахстан, призванных обеспечить устойчивое социальное и экономическое развитие. Применялись также ретроспективный и проектный анализ особенностей протекания процессов экологизации социально-экономической системы Казахстана. Результаты и научная новизна. Раскрыта сущность понятий «зеленая экономика», «экологическое просвещение», «экологическое образование» и «экологизация общества». Показана казахская национальная специфика реализации международных документов по имплементации модели устойчивого развития. Представлена Концепция экологического образования Республики Казахстан, согласно которой система образования страны призвана эффективно формировать, развивать и закреплять, наряду с необходимым комплексом знаний, стереотипы поведения людей, способных принимать целесообразные решения и действовать в соответствии с законодательно закрепленными природоохранными нормами и стандартами. Констатируется, что экологизация содержания образования в республике имеет развитую нормативно-правовую базу, однако необходимы дополнительные меры по модернизации системы образования: ее теоретико-методологическое обоснование, подготовка и повышение квалификации педагогических кадров, разработка новых методических средств, актуализирующих экологическую направленность обучения и воспитания, и т. д. Практическая значимость. Перечислены меры по дальнейшему совершенствованию экологического образования и экологического просвещения на всех ступенях образования.

Economic concept of food development of Russian market

At present, the Russian economy is developing in the conditions of imposed sanctions on high-tech means of production by foreign countries. In this situation, the development vector is the formation of import substitution policies and the solution of food safety issues for various types of food products that are strategically important for human life. Meeting the needs of the country's population with its own production is a priority for the development of the agrarian market, which makes it possible to develop the production agrarian sector, the processing and trade sphere, to create additional jobs, thereby improving the quality and standard of living of people.peer-reviewe

PEDAGOGICAL FRAMEWORKS OF EDUCATION POLICY FOR SUSTAINABLE DEVELOPMENT OF THE EURASIAN SPACE

Introduction. In the context of the widespread environmental degradation as recorded in UN documents, the issues of environmental protection are under active consideration at the international level; the measures for ensuring ecological safety are taken both within the countries and in the global space. It is possible to resolve these issues vital for further human existence only by forming ecological culture and conscientious careful attitude to the nature and environmental conditions among the population; in turn, the questions listed above could not be undertaken without fundamental re-examination of the content of education. The aims of the research presented in the publication are the following: to highlight the main directions of education policy in the Euroasian space; to define key problems of education in behalf of sustainable development of society.Methodology and research methods. Methodological framework of the research is based on the concepts of humanistic pedagogy; holistic and activity approaches to education; principles of nature conformity and co-evolution. The methods of theoretical analysis, synthesis, generalization and modeling were applied in the course of the research.Results and scientific novelty. The authors define the concept of “sustainable development of society”. The main problems that disrupt such development are identified; the main problem is that the declared statements, scientific-theoretical and scientific-practical results in the sphere of sustainable development and noospherism are in contradiction with the existing system of the industrial civilization. The philosophical and pedagogical foundations for formation of noospheric ideology among new generations as alternatives to destructive consumer anthropocentrism are briefly stated. Against this background, the common objectives of “sustainable” education development for the states of Eurasia are outlined; the conditions with an influence on its qualitative characteristics are singled out. These conditions are related to the basic principles proposed by the International Commission on Education that reflect target educational tendencies of the 21st century: “learning to know, learning to do, learning to live together, and learning to be”. It is emphasized that only the constant methodological line of development of social and economic consciousness is adherence to the principle of co-evolution – optimum ratio and coherence between co-development of elements within the triad “person-society-nature”. The institute of education is ascribed the primary role in joint creative evolutionary-gradual process as it is intended to bring up and form the identity of the responsible citizen of the Earth. The possibilities for creation of the educational ecosystem environment functioning are shown by the experience of the Republic of Kazakhstan where the Green Economy Transition (GET) is actively implemented.Practical significance. The authors’ version of an educational ecosystem structure, its way of construction and regulation are demonstrated. It is offered to use anthropo-ecocultural practices-events as educational tools.Введение. В связи с повсеместным, фиксирующимся в документах ООН, ухудшением экологии на международном уровне активно обсуждаются вопросы охраны окружающей среды и принимаются меры по обеспечению экологической безопасности как внутри стран, так и на общем мировом пространстве. Решить эти жизненно важные для дальнейшего существования всего человечества вопросы можно только формируя у населения экологическую культуру и сознательное бережное отношение к природе и среде обитания, что невозможно сделать без кардинального пересмотра содержания образования. Цели представленного в публикации исследования – обозначить магистральные направления образовательной политики в евразийском пространстве и сформулировать ключевые задачи образования в интересах устойчивого развития общества. Методология и методы. Методологической базой исследования являются концептуальные положения гуманистической педагогики, холистический и деятельностный подходы к обучению и воспитанию, принципы природосообразности и коэволюции. В ходе работы применялись методы теоретического анализа, синтеза, обобщения и моделирования. Результаты и научная новизна. Сформулировано авторское определение устойчивого развития общества. Обозначены основные проблемы, мешающие такому развитию, главная из которых заключается в том, что декларируемые заявления, научно-теоретические и научно-практические разработки в сфере устойчивого развития и ноосферизма входят в противоречие со сложившимся устройством техногенной цивилизации. Кратко изложены философско-педагогические основания для становления у новых поколений ноосферного мировоззрения как альтернативы разрушительному потребительскому антропоцентризму. На этом фоне намечены единые для государств Евразии задачи «устойчивого» образования и выделены условия, способные влиять на его качественные характеристики. Данные условия соотнесены с предписанными Международной комиссией по образованию базовыми принципами, отражающими целевые образовательные тенденции XXI века: «учиться жить, учиться познавать, учиться делать и учиться сосуществовать». Подчеркивается, что единственно верной методологической линией развития социально-экономического сознания является следование принципу коэволюции – соблюдению оптимального соотношения и согласованности в соразвитии элементов триады «человек – общество – природа». В совместном созидательном эволюционно-поступательном процессе институту образования отводится первоочередная роль, так как именно оно призвано воспитывать и формировать личность гражданина Земли.На примере опыта Республики Казахстан, где активно осуществляется переход к «зеленой» экономике, показаны возможности создания среды функционирования образовательной экосистемы. Практическая значимость. Продемонстрирован вариант структуры образовательной экосистемы, способ ее построения и регулирования. В качестве средств воспитания и обучения предлагается использовать антропоэкокультурные практики-события

Late Paleocene Flora of the Northern Alaska Peninsula: The Role of Transberingian Plant Migrations and Climatic Change

For the first time, the Late Sagwon Flora is described from the upper beds of the Prince Creek Formation (Upper Paleocene) at the Sagavanirktok River (northern Alaska Peninsula). The flora is dominated by the angiosperm Tiliaephyllum brooksense Moiseeva et Herman sp. nov. and conifer Metasequoia occidentalis (Newb.) Chaney. The Late Sagwon Flora is most similar to the Danian or Danian-Selandian flora from the middle part of the Upper Tsagayan Subformation (Amur Region) and lower part of the Wuyun Formation (Heilongjiang Province, China). This similarity allows us to hypothesize that the genus Tiliaephyllum, which dominated in the Late Tsagayan Flora, migrated via the Bering Land Bridge from southern paleolatitudes of the Far East to high latitudes of the Arctic Pacific, due to the progressively warming climate of the Paleocene. Additional new angiosperm species are described from the Late Sagwon Flora: Archeampelos mullii Moiseeva et Herman sp. nov., Tiliaephyllum brooksense Moiseeva et Herman sp. nov., and Dicotylophyllum sagwonicum Moiseeva et Herman sp. nov

Effectiveness of immunosuppressive therapy for lymphocytic myocarditis according: data from actual clinical practice

Aim. To compare the effectiveness of standard heart failure therapy with and without combined immunosuppressive therapy in patients with documented lymphocytic myocarditis (LM) based on data from actual clinical practice.Material and methods. This observational study included 70 patients with documented LM, 40% (n=28) of whom received immunosuppressive therapy. All patients underwent standard echocardiographic and laboratory investigations, endomyocardial biopsy with histological, immunohistochemical and molecular genetic analysis. Contrast-enhanced cardiac magnetic resonance imaging was performed in 74% of patients. All patients received standard therapy for heart failure at baseline.Results. The groups did not differ in demographic and echocardiographic characteristics. The appointment of immunosuppressive therapy was accompanied by an increase in ejection fraction by 12,2% compared to 6,4% (p=0,02). There were no significant differences in combined endpoints (survival and the need for heart transplantation) depending on therapy regimen (log-rank p=0,97).Conclusion. The prognosis of patients with chronic LM depends on the process activity, the severity of impaired hemodynamics and ventricular arrhythmias, as well as on the presence of persistent viral infection. Compliance with patient selection algorithm before prescribing immunosuppressive therapy is associated with the improvement in myocardial global contractility

Clinical and diagnostic value of including PCR blood test in the traditional algorithm for identifying causative agents of infective endocarditis: a cohort study of 124 patients

Background. If infective endocarditis (IE) is suspected, the determination of the etiology is of fundamental importance for the verification of the disease and the appointment of effective therapy. Microbiological diagnostic features are important, but they often need to be supplemented by culture-independent studies of pathological agents. Aim. To investigate of the diagnostic advantage and value of quantitative analysis of molecular biological methods (polymerase chain reaction PCR, sequencing) in addition to microbiological examination of whole venous blood in IE. Materials and methods. We examined 124 patients with suspected or significant IE (DUKE 2015) hospitalized in the Vinogradov City Clinical Hospital (20152021). All patients underwent parallel microbiological (cultural) and molecular biological (PCR or PCR followed by sequencing) examination of venous whole blood samples. Results. The introduction of an early parallel PCR study into the algorithm for the etiological diagnosis of IE made it possible to obtain an additional advantage in 43/124 (34.7%) patients, which made it possible to exclude unreliable results in the determination of CoNS skin commensals and pathogens atypical for IE or contamination and identify the true pathogens, and also for the first time to isolate the etiopathogenetic pathogen with a negative microbiological study. It was shown that in IE associated with CoNS, the association with the disease was confirmed by PCR in 21.4% (3/14) and refuted in 71.4% (10/14). The coincidence of the results of microbiological and PCR studies of blood samples was obtained only in 35/95 (36.8%). Positive results of PCR analysis of blood of biological material with negative results of culture were obtained in 22/51 (43.1%), of which 2/22 (9.0%) were able to confirm the presence of Bartonella spp DNA. The presented complex algorithm made it possible to significantly increase the possibility of intravital identification of the pathogen in the blood from 58.9 to 76.6%. IE with unknown etiology was present in 29/124 (23.4%) patients. A parallel PCR study allowed timely correction of antibiotic therapy in 43/124 (34.7%) patients. Conclusion. Expansion of indications for the use of PCR studies, primarily whole venous blood samples, is justified, not only in IE with negative results of microbiological examination, but also as a control method for the reliability of the results of traditional (cultural) diagnostic methods

СЛУЧАЙ МЕНИНГОЭНЦЕФАЛИТА У РЕБЕНКА ИЗ ОЧАГА ТУБЕРКУЛЕЗНОЙ ИНФЕКЦИИ

In sectional clause the clinical case of a tubercular meningocephalitis at the child 6 years from the center drug resistant bacterial excretion is described. The analysis of the parents and risk factors of occurrence sectional astroprocessor of the shape of tuberculosis is given.Описан клинический случай туберкулезного менингоэнцефалита у ребенка 6 лет из очага лекарственно-устойчивого бактериовыделения туберкулеза. Приведен анализ причин и факторов риска возникновения данной остро прогрессирующей формы туберкулеза.

State of health of the children's population and prospects of development paediatrics service of the Udmurt republic

By the purpose of sectional examination was to reveal a modern state of health of the children's population, to spot prospects of development pediatric of a service of the Udmurt Republic. For reception of the information the traditional receptions and methods of study of a state of health of children regulated by effective legal basis were utilized. Fixed, that the state of health of the children's population of Udmurtiya is worsened, in connection with, than the introduction sparing health of technologies is necessary. By the reasons of progressive deterioration of health of children were an acceleration of stressful situations in daily life of children, intensification of educational process, deterioration of power supply of children, both in educational establishment, and in family, rising of a load on an organism of the child of the factors of ecological hazard, considerable propagation of abundance among children asocial and deviation of the shapes of behavior. The organizational and practical operation of an operating controls of public health services in the field of protection of a maternity and childhood is guided on maintenance of availability and rising of quality of a medical care to the women and children, down stroke of a maternal, children's and infantile case rate and mortalities, decrease of children’s physical inability.Целью данного исследования была оценка современного состояния здоровья детского населения, определение перспективы развития педиатрической службы Удмуртской Республики. Материалы и методы. Для получения информации использовались традиционные приемы и методы изучения состояния здоровья детей, регламентированные действующей нормативно-правовой базой. Результаты и обсуждение. Установлено, что состояние здоровья детского населения Удмуртии ухудшается, в связи с чем, необходимо внедрение здоровьесберегающих технологий. Причинами прогрессивного ухудшения здоровья детей явились учащение стрессовых ситуаций в повседневной жизни детей, интенсификация учебного процесса, ухудшение качества питания детей, как в образовательном учреждении, так и в семье, повышение нагрузки на организм ребенка факторов экологического риска, значительный рост распространенности среди детей асоциальных и девиантных форм поведения. Организационная и практическая работа органов управления здравоохранения в области охраны материнства и детства должна быть направлена на обеспечение доступности и повышение качества медицинской помощи женщинам и детям, снижение материнской, детской и младенческой заболеваемости и смертности, уменьшение дет-ской инвалидности

Galectin-1 Is Part of Human Trophoblast Invasion Machinery - A Functional Study In Vitro

Interactions of glycoconjugates with endogenous galectins, have been long proposed to participate in several reproductive processes including implantation. In human placenta gal-1, gal-3, gal-8, and gal-13 proteins are known to be present. Each of them has been proposed to play multiple functions, but so far no clear picture has emerged. We hypothesized that gal-1 participates in trophoblast invasion, and conducted Matrigel invasion assay using isolated cytotrophoblast from first trimester placenta and HTR-8/SVneo cell line to test it.<0.001) by Ox-gal-1 at 1 µg/ml. Both sets of results confirmed involvement of gal-1 in trophoblast invasion. Galectin profile of isolated cytotrophoblast and HTR-8/SVneo cells was established using RT-PCR and real-time PCR and found to consist of gal-1, gal-3 and gal-8 for both cell types. Only gal-1 was located at the trophoblast cell membrane, as determined by FACS analysis, which is consistent with the results of the functional tests.These findings qualify gal-1 as a member of human trophoblast cell invasion machinery