434 research outputs found
Investigating the relationship between actual smartphone use and delay discounting
The omnipresence of smartphones among adolescents and adults gives rise to the questions about excessive use and personality factors which are associated with heavier engagement with these devices. Previous studies have found behavioral similarities between smartphone use and maladaptive behaviors (e.g. drinking, gambling, drug abuse) in the context of intertemporal choice but mostly relied on participantsâ self-reports regarding engagement with their phone. In this study, we collected actual usage data by smartphone application from 101 participants and assessed their tendency to discount future rewards, their reward responsiveness, self-control and consideration of future consequences. We found that smartphone screen time was correlated with choosing smaller immediate over larger delayed rewards and that usage of social media and gaming apps predicted delay discounting. Additionally, smartphone use was negatively correlated with self-control but not correlated with consideration of future consequences. Neither psychological variable could mediate the relationship between smartphone usage and delay discounting. Our findings provide further evidence that smartphone use and impulsive decision-making go hand in hand and that engagement with these devices needs to be critically examined by researchers to guide prudent behavior
Delay Discounting of Monetary and Social Media Rewards: Magnitude and Trait Effects
Humans discount rewards as a function of the delay to their receipt. This tendency is referred to as delay discounting and has been extensively researched in the last decades. The magnitude effect (i.e., smaller rewards are discounted more steeply than larger rewards) and the trait effect (i.e., delay discounting of one reward type is predictive of delay discounting of other reward types) are two phenomena which have been consistently observed for a variety of reward types. Here, we wanted to investigate if these effects also occur in the context of the novel but widespread reward types of Instagram followers and likes and if delay discounting of these outcomes is related to self-control and Instagram screen time. In a within-subject online experiment, 214 Instagram users chose between smaller, immediate and larger, delayed amounts of hypothetical money, Instagram followers and likes. First, we found that the magnitude effect also applies to Instagram followers and likes. Second, delay discounting of all three reward types was correlated, providing further evidence for a trait influence of delay discounting. Third, no relationships were found between delay discounting and self-control as well as Instagram screen time, respectively. However, a userâs average like count was related to delay discounting of Instagram likes
Attraction effect in risky choice can be explained by subjective distance between choice alternatives
Individuals make decisions under risk throughout daily life. Standard models of economic decision making typically assume that people evaluate choice options independently. There is, however, substantial evidence showing that this independence assumption is frequently violated in decision making without risk. The present study extends these findings to the domain of decision making under risk. To explain the independence violations, we adapted a sequential sampling model, namely Multialternative Decision Field Theory (MDFT), to decision making under risk and showed how this model can account for the observed preference shifts. MDFT not only better predicts choices compared with the standard Expected Utility Theory, but it also explains individual differences in the size of the observed context effect. Evidence in favor of the chosen option, as predicted by MDFT, was positively correlated with brain activity in the medial orbitofrontal cortex (mOFC) and negatively correlated with brain activity in the anterior insula (aINS). From a neuroscience perspective, the results of the present study show that specific brain regions, such as the mOFC and aINS, not only code the value or risk of a single choice option but also code the evidence in favor of the best option compared with other available choice options
Music-evoked incidental happiness modulates probability weighting during risky lottery choices
We often make decisions with uncertain consequences. The outcomes of the choices we make are usually not perfectly predictable but probabilistic, and the probabilities can be known or unknown. Probability judgments, i.e., the assessment of unknown probabilities, can be influenced by evoked emotional states. This suggests that also the weighting of known probabilities in decision making under risk might be influenced by incidental emotions, i.e., emotions unrelated to the judgments and decisions at issue. Probability weighting describes the transformation of probabilities into subjective decision weights for outcomes and is one of the central components of cumulative prospect theory (CPT) that determine risk attitudes. We hypothesized that music-evoked emotions would modulate risk attitudes in the gain domain and in particular probability weighting. Our experiment featured a within-subject design consisting of four conditions in separate sessions. In each condition, the 41 participants listened to a different kind of music-happy, sad, or no music, or sequences of random tones-and performed a repeated pairwise lottery choice task. We found that participants chose the riskier lotteries significantly more often in the "happy" than in the "sad" and "random tones" conditions. Via structural regressions based on CPT, we found that the observed changes in participants' choices can be attributed to changes in the elevation parameter of the probability weighting function: in the "happy" condition, participants showed significantly higher decision weights associated with the larger payoffs than in the "sad" and "random tones" conditions. Moreover, elevation correlated positively with self-reported music-evoked happiness. Thus, our experimental results provide evidence in favor of a causal effect of incidental happiness on risk attitudes that can be explained by changes in probability weighting
Electron Self Energy for the K and L Shell at Low Nuclear Charge
A nonperturbative numerical evaluation of the one-photon electron self energy
for the K- and L-shell states of hydrogenlike ions with nuclear charge numbers
Z=1 to 5 is described. Our calculation for the 1S state has a numerical
uncertainty of 0.8 Hz in atomic hydrogen, and for the L-shell states (2S and
2P) the numerical uncertainty is 1.0 Hz. The method of evaluation for the
ground state and for the excited states is described in detail. The numerical
results are compared to results based on known terms in the expansion of the
self energy in powers of (Z alpha).Comment: 21 pages, RevTeX, 5 Tables, 6 figure
Calculation of the Electron Self Energy for Low Nuclear Charge
We present a nonperturbative numerical evaluation of the one-photon electron
self energy for hydrogenlike ions with low nuclear charge numbers Z=1 to 5. Our
calculation for the 1S state has a numerical uncertainty of 0.8 Hz for hydrogen
and 13 Hz for singly-ionized helium. Resummation and convergence acceleration
techniques that reduce the computer time by about three orders of magnitude
were employed in the calculation. The numerical results are compared to results
based on known terms in the expansion of the self energy in powers of (Z
alpha).Comment: 10 pages, RevTeX, 2 figure
Correspondence: Are Cognitive Functions Localizable? Colin Camerer et al. versus Marieke van Rooij and John G. Holden
The Fall 2011 issue of this journal published a
two-paper section on âNeuroeconomics.â One
paper, by Ernst Fehr and Antonio Rangel, clearly
and concisely summarized a small part of the fast-growing
literature. The second paper, âItâs about
Space, Itâs about Time, Neuroeconomics, and the
Brain Sublime,â by Marieke van Rooij and Guy Van
Orden, is beautifully written and enjoyable to read,
but misleading in many critical ways. A number
of economists and neuroscientists working at the
intersection of the two fields shared our reaction
and have signed this letter, as shown below. Some of
the paperâs descriptions of empirical findings and
methods in neuroeconomics are incomplete, badly
out of date, or flatly wrong. In studies the authors
describe in detail, their skeptical interpretations
have often been refuted by published data, old and
new, that they overlook
A transcriptomic snapshot of early molecular communication between Pasteuria penetrans and Meloidogyne incognita
© The Author(s). 2018Background: Southern root-knot nematode Meloidogyne incognita (Kofoid and White, 1919), Chitwood, 1949 is a key pest of agricultural crops. Pasteuria penetrans is a hyperparasitic bacterium capable of suppressing the nematode reproduction, and represents a typical coevolved pathogen-hyperparasite system. Attachment of Pasteuria endospores to the cuticle of second-stage nematode juveniles is the first and pivotal step in the bacterial infection. RNA-Seq was used to understand the early transcriptional response of the root-knot nematode at 8 h post Pasteuria endospore attachment. Results: A total of 52,485 transcripts were assembled from the high quality (HQ) reads, out of which 582 transcripts were found differentially expressed in the Pasteuria endospore encumbered J2 s, of which 229 were up-regulated and 353 were down-regulated. Pasteuria infection caused a suppression of the protein synthesis machinery of the nematode. Several of the differentially expressed transcripts were putatively involved in nematode innate immunity, signaling, stress responses, endospore attachment process and post-attachment behavioral modification of the juveniles. The expression profiles of fifteen selected transcripts were validated to be true by the qRT PCR. RNAi based silencing of transcripts coding for fructose bisphosphate aldolase and glucosyl transferase caused a reduction in endospore attachment as compared to the controls, whereas, silencing of aspartic protease and ubiquitin coding transcripts resulted in higher incidence of endospore attachment on the nematode cuticle. Conclusions: Here we provide evidence of an early transcriptional response by the nematode upon infection by Pasteuria prior to root invasion. We found that adhesion of Pasteuria endospores to the cuticle induced a down-regulated protein response in the nematode. In addition, we show that fructose bisphosphate aldolase, glucosyl transferase, aspartic protease and ubiquitin coding transcripts are involved in modulating the endospore attachment on the nematode cuticle. Our results add new and significant information to the existing knowledge on early molecular interaction between M. incognita and P. penetrans.Peer reviewedFinal Published versio
Efficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis
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