399 research outputs found
Understanding Generation Z Students to Promote a Contemporary Learning Environment
University faculty predominantly represent the Baby Boomer and Baby Buster (Gen X) Generations, but, university students are largely iYs Millenials and Generation Z Digital Natives. These groups have been characterized both positively and negatively in the popular press. A fresh understanding of the newer generations can help instructors better meet current students’ educational needs. This article shares brief generational profiles based on recent research and then presents questions and recommendations for improving course assignments and their effectiveness. Ways of communicating about assignments and their benefits are also shared. The goal is to equip college-level instructors with ways to relate to and support the newest generation of learners
Precise calculation of transition frequencies of hydrogen and deuterium based on a least-squares analysis
We combine a limited number of accurately measured transition frequencies in
hydrogen and deuterium, recent quantum electrodynamics (QED) calculations, and,
as an essential additional ingredient, a generalized least-squares analysis, to
obtain precise and optimal predictions for hydrogen and deuterium transition
frequencies. Some of the predicted transition frequencies have relative
uncertainties more than an order of magnitude smaller than that of the g-factor
of the electron, which was previously the most accurate prediction of QED.Comment: 4 pages, RevTe
Relativistic and Radiative Energy Shifts for Rydberg States
We investigate relativistic and quantum electrodynamic effects for
highly-excited bound states in hydrogenlike systems (Rydberg states). In
particular, hydrogenic one-loop Bethe logarithms are calculated for all
circular states (l = n-1) in the range 20 <= n <= 60 and successfully compared
to an existing asymptotic expansion for large principal quantum number n. We
provide accurate expansions of the Bethe logarithm for large values of n, for
S, P and circular Rydberg states. These three expansions are expected to give
any Bethe logarithms for principal quantum number n > 20 to an accuracy of five
to seven decimal digits, within the specified manifolds of atomic states.
Within the numerical accuracy, the results constitute unified, general formulas
for quantum electrodynamic corrections whose validity is not restricted to a
single atomic state. The results are relevant for accurate predictions of
radiative shifts of Rydberg states and for the description of the recently
investigated laser-dressed Lamb shift, which is observable in a strong
coherent-wave light field.Comment: 8 pages; RevTeX
The Grizzly, April 17, 2003
Silence Broken: Filmmaker Tells Story of Korean Comfort Women • Is Registration a Class Act or a Big Headache? • Ursinus Students Making a Mark • No Place Like Home • Opinion: If Environmentalists Succeed, They Will Make Human Life Impossible • Senior Class Gift Drive • Meeting Wynton • Airband Review • Easter History • Women\u27s LAX Can\u27t Stop the Rain • UC Softball Beats F&Mhttps://digitalcommons.ursinus.edu/grizzlynews/1535/thumbnail.jp
Use of Genetic Stock Identification Data for Comparison of the Ocean Spatial Distribution, Size at Age, and Fishery Exposure of an Untagged Stock and Its Indicator: California Coastal versus Klamath River Chinook Salmon
Managing weak stocks in mixed-stock fisheries often relies on proxies derived from data-rich indicator stocks. For example, full cohort reconstruction of tagged Klamath River fall run Chinook salmon (Oncorhynchus tshawytscha) of northern California, USA, enables the use of detailed models to inform management. Information gained from this stock is also used in the management of the untagged, threatened California Coastal Chinook (CCC) salmon stock, by capping Klamath harvest rates. To evaluate use of this proxy, we used genetic stock identification (GSI) data to compare the two stocks\u27 size-at-age and ocean distribution, two key factors influencing fishery exposure. We developed methods to account for both sampling and genetic assignment uncertainty in catch estimates. We found that, in 2010, the stocks were similar in size-at-age early in the year (age-3 and age-4), but CCC fish were larger later in the year. The stocks appeared similarly distributed early in the year (2010), but more concentrated near their respective source rivers later in the year (2010 and 2011). If these results are representative, relative fishery impacts on the two stocks might scale similarly early in the year but management changes later in the year might have differing impacts on the two stocks
Modelling Costs of Interventional Pulmonary Embolism Treatment: Implications of US Trends for a European Healthcare System
BACKGROUND
Catheter-directed treatment (CDT) of acute pulmonary embolism (PE) is entering a growth phase in Europe following a steady increase in the United States (US) in the past decade, but the potential economic impact on European healthcare systems remains unknown.
METHODS AND RESULTS
We built two statistical models for the monthly trend of proportion of CDT among patients with severe (intermediate- or high-risk) PE in the US. The conservative model was based on admission data from the National Inpatient Sample (NIS) 2016-2020, and the model reflecting increasing access to advanced treatment from the PERTTM national quality assurance database registry 2018-2021. By applying these models to the forecast of annual PE-related hospitalizations in Germany, we calculated the annual number of severe PE cases and the expected increase in CDT use for the period 2025-2030. The NIS-based model yielded a slow increase, reaching 3.1% (95% CI 3.0-3.2%) among all hospitalizations with PE in 2030; in the PERT-based model, increase would be steeper, reaching 8.7% (8.3-9.2%). Based on current reimbursement rates, we estimated an increase of annual costs for PE-related hospitalizations in Germany ranging from 15.3 to 49.8 million euros by 2030. This calculation does not account for potential cost savings, including those from reduced length of hospital stay.
CONCLUSION
Our approach and results, which may be adapted to other European healthcare systems, provide a benchmark for healthcare costs expected to result from CDT. Data from ongoing trials on clinical benefits and cost savings are needed to determine cost-effectiveness and inform reimbursement decisions
Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission
iGluSnFR variants with improved signal-to-noise ratios and targeting to postsynaptic sites have been developed, enabling the analysis of glutamatergic neurotransmission in vivo as illustrated in the mouse visual and somatosensory cortex. The fluorescent glutamate indicator iGluSnFR enables imaging of neurotransmission with genetic and molecular specificity. However, existing iGluSnFR variants exhibit low in vivo signal-to-noise ratios, saturating activation kinetics and exclusion from postsynaptic densities. Using a multiassay screen in bacteria, soluble protein and cultured neurons, we generated variants with improved signal-to-noise ratios and kinetics. We developed surface display constructs that improve iGluSnFR's nanoscopic localization to postsynapses. The resulting indicator iGluSnFR3 exhibits rapid nonsaturating activation kinetics and reports synaptic glutamate release with decreased saturation and increased specificity versus extrasynaptic signals in cultured neurons. Simultaneous imaging and electrophysiology at individual boutons in mouse visual cortex showed that iGluSnFR3 transients report single action potentials with high specificity. In vibrissal sensory cortex layer 4, we used iGluSnFR3 to characterize distinct patterns of touch-evoked feedforward input from thalamocortical boutons and both feedforward and recurrent input onto L4 cortical neuron dendritic spines
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Use of Genetic Stock Identification Data for Comparison of the Ocean Spatial Distribution, Size at Age, and Fishery Exposure of an Untagged Stock and Its Indicator: California Coastal versus Klamath River Chinook Salmon
Managing weak stocks in mixed-stock fisheries often relies on proxies derived from data-rich indicator stocks, although there have been limited tests of the appropriateness of such proxies. For example, full cohort reconstruction of tagged Klamath River fall-run Chinook Salmon Oncorhynchus tshawytscha of northern California enables the use of detailed models to inform management. Information gained from this stock is also used in the management of the untagged, threatened California Coastal Chinook Salmon (CCC) stock, where it is assumed that a cap on Klamath harvest rates effectively constrains impacts on CCC to acceptable levels. To evaluate use of this proxy, we used a novel approach based on genetic stock identification (GSI) data to compare the two stocks’ size at age and ocean distribution (as inferred from spatial variation in CPUE), two key factors influencing fishery exposure. We developed broadly applicable methods to account for both sampling and genetic assignment uncertainty in estimating total stock-specific catch from GSI data, and propagated this uncertainty into models quantifying variation in CPUE across space and time. We found that, in 2010, the stocks were similar in size at age early in the year (age 3 and age 4), but CCC fish were larger later in the year. The stocks appeared similarly distributed early in the year (2010) but more concentrated near their respective source rivers later in the year (2010 and 2011). If these results are representative, relative fishery impacts on the two stocks might scale similarly early in the year, but management changes later in the year could have differing impacts on the two stocks. This novel modeling approach is suited to evaluating the concordance between other data-limited stocks and their proxies, and can be broadly applied to estimate stock-specific harvest, and the uncertainty therein, using GSI in other systems
Highly functionalized organic nitrates in the southeast United States : Contribution to secondary organic aerosol and reactive nitrogen budgets
Speciated particle-phase organic nitrates (pONs) were quantified using online chemical ionization MS during June and July of 2013 in rural Alabama as part of the Southern Oxidant and Aerosol Study. A large fraction of pONs is highly functionalized, possessing between six and eight oxygen atoms within each carbon number group, and is not the common first generation alkyl nitrates previously reported. Using calibrations for isoprene hydroxynitrates and the measured molecular compositions, we estimate that pONs account for 3% and 8% of total submicrometer organic aerosol mass, on average, during the day and night, respectively. Each of the isoprene-and monoterpenes-derived groups exhibited a strong diel trend consistent with the emission patterns of likely biogenic hydrocarbon precursors. An observationally constrained diel box model can replicate the observed pON assuming that pONs (i) are produced in the gas phase and rapidly establish gas-particle equilibrium and (ii) have a short particle-phase lifetime (similar to 2-4 h). Such dynamic behavior has significant implications for the production and phase partitioning of pONs, organic aerosol mass, and reactive nitrogen speciation in a forested environment.Peer reviewe
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