Optimal PV Allocation & Minimal tap-Changing Transformers Achieving Best Distribution Voltage Profile & Minimum Losses in Active Distribution Networks

In distribution systems, voltage levels of the various buses should be maintained within the permissible limits for satisfactory operation of all electrical installations and equipment.  The task of voltage control is closely associated with fluctuating load conditions and corresponding requirements of reactive power compensation. The problem of load bus voltage optimization in distribution systems that have distributed generation (DG) has recently become an issue. In Oman, the distribution code limits the load bus voltage variations within ±6% of the nominal value. Several voltage control methods are employed in active distribution systems with a high share of photovoltaic systems (PV) to keep the voltage levels within the desirable limits. In addition to the constraint of targeting the best voltage profile, another constraint has to be achieved which is the minimum loss in the distribution network. An optimised solution for voltage of load busses with on-load tap-changing (OLTC) tarnsformers and PV sources is presesnted in this paper. This study addresses the problem of optimizing the injected power from PV systems associated with the facilities of tap-changing transformers, as it is an important means of controlling voltage throughout the system.  To avoid violating tap-changing constraints, a method is depicted for determining the minimal changes in transformer taps to control voltage levels with distributed PV sources.  The taps of a range + 5 to -15 %, can be achieved by tap-changing transformers. The OLTC operation was designed to keep the secondary bus within the voltage standard for MV networks

Design of Robust Digital Pole Placer for Car Active Suspension with Input Constraint

This chapter deals with the problem of state feedback control for an active quarter-car suspension system with control input constraint. The dynamics of the suspension system is first formed in terms of the control objectives: ride comfort, suspension deflection, and maximum actuator control force. The control task is formulated as robustly placing the closed poles in a desired region against different passenger load. Since digital computers are widely used in the vehicle industry, a new saturated controller design method is presented for regional pole-placement of uncertain discrete time systems. The constraint of control input saturation is considered in the design phase. The desired dynamic performance for uncertain discrete-time systems is represented by the settling time and damping ratio. A sufficient condition is derived to place the poles in a desired region. The design is formulated in terms of linear matrix inequality optimization. The effectiveness of the proposed design is illustrated by applying it to a quarter?car active suspension system. Different road tests for the proposed controller are carried out: step and bump disturbances. The proposed design achieves the desired oscillation damping due to road disturbances in addition to passenger comfort. The results are compared with the passive suspension system

Protective effect of camel milk as anti-diabetic supplement: biochemical, molecular and immunohistochemical study

Background: Diabetes is a serious disease affects human health. Diabetes in advanced stages is accompanied by general weakness and alteration in fats and carbohydrates metabolism. Recently there are some scientific trends about the usage of camel milk (CM) in the treatment of diabetes and its associated alterations. CM contains vital active particles with insulin like action that cure diabetes and its complications but how these effects occur, still unclear.Materials and Methods: Seventy-five adult male rats of the albino type divided into five equal groups. Group 1 served as a negative control (C). Group 2 was supplemented with camel milk (CM). Diabetes was induced in the remaining groups (3, 4 and 5). Group 3 served as positive diabetic control (D). Group 4 served as diabetic and administered metformin (D+MET). Group 5 served as diabetes and supplemented with camel milk (D+CM). Camel milk was supplemented for two consecutive months. Serum glucose, leptin, insulin, liver, kidney, antioxidants, MDA and lipid profiles were assayed. Tissues from liver and adipose tissues were examined using RT-PCR analysis for the changes in mRNA expression of genes of carbohydrates and lipid metabolism. Pancreas and liver were used for immunohistochemical examination using specific antibodies.Results: Camel milk supplementation ameliorated serum biochemical measurements that altered after diabetes induction. CM supplementation up-regulated mRNA expression of IRS-2, PK, and FASN genes, while down-regulated the expression of CPT-1 to control mRNA expression level. CM did not affect the expression of PEPCK gene. On the other hand, metformin failed to reduce the expression of CPT-1 compared to camel milk administered rats. Immunohistochemical findings revealed that CM administration restored the immunostaining reactivity of insulin and GLUT-4 in the pancreas of diabetic rats.Conclusion: CM administration is of medical importance and helps physicians in the treatment of diabetes mellitus.Keywords: Camel milk, Diabetes, Gene expression, Immunohistochemistr

Analysis of Wind Turbine Driven Permanent Magnet Synchronous Generator under Different Loading Conditions

This paper proposes the configuration of a Wind Turbine generating system equipped with Permanent Magnet Synchronous Generator (PMSG). There are different types of synchronous generators, but the PMSG is chosen which has better performance due to higher efficiency and less maintenance. Since it can be used without a gearbox also implies a reduction of the weight of the nacelle and a reduction of costs. The model includes a wind turbine model, drive train model and PMSG model. The equations that explain their behavior have been introduced. The generator model is established in the d-q synchronous rotating reference frame. The proposed Wind Turbine Generator System (WTGS) has been implemented in MATLAB/SIMULINK software. The PMSG is operating in stand-alone which is loaded with different types of loads. The simulation results indicate the ability of wind driven PMSG to operate over wide range of operating conditions at different loading conditions and show effect of different load types in operation. Keywords: Permanent Magnet Synchronous Generator (PMSG), Wind Turbine, Wind Energy and WTGS MATLAB/SIMULINK

Embedded two level direct adaptive fuzzy controller for DC motor speed control

AbstractThis paper presents a proposed approach based on an adaptive fuzzy logic controller for precise control of the DC motor speed. In this concern, the proposed Direct Adaptive Fuzzy Logic Controller (DAFLC) is estimated from two levels, where the lower level uses a Mamdani fuzzy controller and the upper level is an inverse model based on a Takagi–Sugeno (T–S) method in which its output is used to adapt the parameters of the fuzzy controller in the lower level. The proposed controller is implemented using an Arduino DUE kit. From the practical results, it is proved that the proposed adaptive controller improves, successfully both the performance response and the disturbance due to the load in the speed control of the DC motor

Adenosine A2A Receptor Blockade Prevents Rotenone-Induced Motor Impairment in a Rat Model of Parkinsonism

Pharmacological studies implicate the blockade of adenosine receptorsas an effective strategy for reducing Parkinson’s disease (PD) symptoms. The objective of this study is to elucidate the possible protective effects of ZM241385 and 8-cyclopentyl-1, 3-dipropylxanthine, two selective A2A and A1 receptor antagonists, on a rotenone rat model of PD. Rats were split into four groups: vehicle control (1 ml/kg/48 h), rotenone (1.5 mg/kg/48 h, s.c.), ZM241385 (3.3 mg/kg/day, i.p) and 8-cyclopentyl-1, 3-dipropylxanthine (5 mg/kg/day, i.p). After that, animals were subjected to behavioral (stride length and grid walking) and biochemical (measuring concentration of dopamine levels using high performance liquid chromatography, HPLC). In the rotenone group, rats displayed a reduced motor activity and disturbed movement coordination in the behavioral tests and a decreased dopamine concentration as foundby HPLC. The effect of rotenone was partially prevented in the ZM241385 group, but not with 8-cyclopentyl-1,3-dipropylxanthine administration. The administration of ZM241385 improved motor function and movement coordination (partial increase of stride length and partial decrease in the number of foot slips) and an increase in dopamine concentration in the rotenone-injected rats. However, the 8-cyclopentyl-1,3-dipropylxanthine and rotenone groups were not significantly different. These results indicate that selective A2A receptor blockade by ZM241385, but not A1 receptor blockadeby 8-cyclopentyl-1,3-dipropylxanthine, may treat PD motor symptoms. This reinforces the potential use of A2A receptor antagonists as a treatment strategy for PD patients

PROTECTIVE EFFECT OF CAMEL MILK AS ANTI-DIABETIC SUPPLEMENT: BIOCHEMICAL, MOLECULAR AND IMMUNOHISTOCHEMICAL STUDY

Background: Diabetes is a serious disease affects human health. Diabetes in advanced stages is accompanied by general weakness and alteration in fats and carbohydrates metabolism. Recently there are some scientific trends about the usage of camel milk (CM) in the treatment of diabetes and its associated alterations. CM contains vital active particles with insulin like action that cure diabetes and its complications but how these effects occur, still unclear. Materials and Methods: Seventy-five adult male rats of the albino type divided into five equal groups. Group 1 served as a negative control (C). Group 2 was supplemented with camel milk (CM). Diabetes was induced in the remaining groups (3, 4 and 5). Group 3 served as positive diabetic control (D). Group 4 served as diabetic and administered metformin (D+MET). Group 5 served as diabetes and supplemented with camel milk (D+CM). Camel milk was supplemented for two consecutive months. Serum glucose, leptin, insulin, liver, kidney, antioxidants, MDA and lipid profiles were assayed. Tissues from liver and adipose tissues were examined using RT-PCR analysis for the changes in mRNA expression of genes of carbohydrates and lipid metabolism. Pancreas and liver were used for immunohistochemical examination using specific antibodies. Results: Camel milk supplementation ameliorated serum biochemical measurements that altered after diabetes induction. CM supplementation up-regulated mRNA expression of IRS-2, PK, and FASN genes, while down-regulated the expression of CPT-1 to control mRNA expression level. CM did not affect the expression of PEPCK gene. On the other hand, metformin failed to reduce the expression of CPT-1 compared to camel milk administered rats. Immunohistochemical findings revealed that CM administration restored the immunostaining reactivity of insulin and GLUT-4 in the pancreas of diabetic rats. Conclusion: CM administration is of medical importance and helps physicians in the treatment of diabetes mellitus

Case report: Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus

BackgroundAutoimmune lymphoproliferative syndrome (ALPS) is a rare disease characterized by defective FAS signaling, which results in chronic, nonmalignant lymphoproliferation and autoimmunity accompanied by increased numbers of “double-negative” T-cells (DNTs) (T-cell receptor αβ+ CD4−CD8−) and an increased risk of developing malignancies later in life.Case presentationWe herein report a case of a newborn boy with a novel germline homozygous variant identified in the FAS gene, exon 9, c.775del, which was considered pathogenic. The consequence of this sequence change was the creation of a premature translational stop signal p.(lle259*), associated with a severe clinical phenotype of ALPS-FAS. The elder brother of the proband was also affected by ALPS and has been found to have the same FAS homozygous variant associated with a severe clinical phenotype of ALPS-FAS, whereas the unaffected parents are heterozygous carriers of this variant. This new variant has not previously been described in population databases (gnomAD and ExAC) or in patients with FAS-related conditions. Treatment with sirolimus effectively improved the patient clinical manifestations with obvious reduction in the percentage of DNTs.ConclusionWe described a new ALPS-FAS clinical phenotype-associated germline FAS homozygous pathogenic variant, exon 9, c.775del, that produces a premature translational stop signal p.(lle259*). Sirolimus significantly reduced DNTs and substantially relieved the patient's clinical symptoms

The Role of Technology in Preventive Measures to Combat Money Laundering Crime: Case study Sudan

This study aimed to highlight the role that technology can play in the preventive measures to combat money laundering, especially since money laundering crimes have become dependent on advanced technical techniques in addition to many electronic means that are currently available. This necessitated the development of advanced technical means and tools to combat money laundering. The researchers used the case study methodology, which is characterized by many advantages that make it suitable for this study, including that it allows the collection of data from multiple sources. The study reached many results, the most prominent of which is that the phenomenon of money laundering passes in most of the stage of transfers through bank accounts, which must provide a degree of banking secrecy for customer accounts, which makes the matter of balancing between combating money laundering and maintaining the secrecy of customer accounts difficult and not Palliser. The most prominent of the recommendations of this study is that the legislation and laws of money laundering crimes must be revised and followed up with the necessary decisive, strict and rapid amendments, at least annually