Introduction of Purple and Deep Purple F1 Carrot Hybrids to Egypt Showed High Antioxidant Activity and High Content of Total Flavonoids and Phenols

For the improvement of carrot cultivation in Egypt and because of the deterioration of the local Egyptian purple carrots, two novel colored (Purple and Deep Purple) F1 carrot hybrids were introduced for the first time from Netherland to be evaluated and compared to the broadly cultivated yellow Japanese F1 hybrid (Kuruda) under the Middle Egypt sandy soil growing conditions. The horticultural evaluation showed that the two purple hybrids have elongated thick roots and good vegetative growth and gave a very high yield of roots in two successive winter seasons of 2013/2014 and 2014/2015. The Deep Purple hybrid exceeded the other two hybrids in almost all studied chemical and horticultural characteristics. It showed about three folds of leaves fresh weight/plant, two folds of both root fresh weight/plant and yield/m2 when compared with Purple and Kuruda hybrids. The chemical analyses declared that the Purple and Deep Purple hybrids have higher contents of all estimated components and the Deep Purple hybrid had the highest values of total flavonoids (about two folds), total phenols (about 5-6 folds), antioxidant activity percentage (7-8 times), and total soluble solids percentage (1.5-2 times) than that of the yellow F1 hybrid “Kuruda”. These newly introduced two Purple and Deep Purple F1 hybrids may be very promising in production and processing purposes of purple carrots and good materials in carrot breeding programs in Egypt

Evaluation of pediatric bradycardia: A single center experience

Background: Heart rate is an integral part of the clinical assessment of the children with acute illness and is commonly used in pediatric early warning scores. Objective: The aim of this study was to assess our current practice for evaluation and management of bradycardia in children. Patients and methods: The study was conducted in Pediatric Arrhythmia Clinic, Neonatal Intensive Care Unit and Pediatric Intensive Care Unit from March 2020 to August 2021. 61 Neonates and children aged from 1 day to 18 years presenting with bradycardia were included in this study. Predeath bradycardia was excluded. Full medical history, physical examination, basic investigations, 12 leads ECG and echocardiography were performed to all patients. Thyroid function tests, 24 hours Holter monitoring, and stress ECG were done if indicated. Results: 61 patients were included in the study. Heart rate ranged from 44 to 94 beat/minute with mean 69.44 beat/minute, the most common form of presentation was abnormal echocardiography. Hypocalcemia was present in 85.2% of patients. 70.5% of patients had sinus bradycardia, 13% had complete heart block (CHB),10% of patients had long QTc Syndrome with sinus bradycardia, 3.3% had 1st and 2nd degree heart block, 1.6% had ECG changes of ALCAPA with sinus bradycardia and 1.6% had ventricular ectopic. Conclusion: It could be concluded that bradycardia in children needs accurate assessment to rule out the need of acute intervention and to decrease the risk of life-threatening conditions

The Role of Acid Sites in the Catalytic Performance of Tungsten Oxide during the Dehydration of Isopropyl and Methyl Alcohols

Abstract WO 3 catalyst was prepared by thermal decomposition of ammonium metatungstate (AMT) in a static air atmosphere for 3h at 450, 550, 650 and 750 o C. The techniques employed for characterization of the catalyst were TG, DTA, XRD, FTIR, N 2 -sorption measurements. The surface acidity of the catalyst was investigated by adsorption of pyridine and 2, 6-dimethyl pyridine. The catalytic properties of the catalyst were carried out for the dehydration of isopropyl and methyl alcohols. The results revealed that WO 3 is more active toward isopropanol dehydration than methanol dehydration. Also reflect that the reaction mechanism and the yield of propene and dimethyl ether produced from dehydration of isopropyl and methyl alcohols are controlled by the strength of acid sites

Oxide Film Destruction on Al-Mg Alloys in HCl Solutions

Open circuit potential technique is used to follow the oxide film destruction of three of Al-Mg alloys in HCl solutions of varying concentrations.  Dissolution of the passive film on pare metal surface takes place in two distinct steps indicating that the film is composed mainly of a barrier layer of Al2O3 adjacent to the metal surface and an outer porous modification on the top of the first one. The rates of oxide film destruction and/or dissolution (δ1¯ and δ2¯) follow a direct logarithmic law. The extent of oxide film destruction and metal dissolution were found to increase with increasing the acid concentration and the percent of Mg content in the alloy sample

Bio- and Sequence Stratigraphy of Upper Cretaceous – Palaeogene rocks, East Bahariya Concession, Western Desert, Egypt

This work deals with the plankton stratigraphy of the subsurface Upper Cretaceous-Palaeogene succession of theEast Bahariya Concession based on planktonic foraminifera and calcareous nannofossils. The examination of the cuttings from five wells: AQSA-1X, KARMA-E-1X, KARMA-3X, KARMA-NW-1X and KARMA-NW-5X is biostratigraphically evaluated. It is possible to identify the planktonic foraminifera as well as the calcareous nannofossil biozones. The analyses of calcareous nannofossils revealed the presence of several hiatuses. Information obtained from well data such as seismic facies analysis for the studied area has enabled classification of the Upper Cretaceous Palaeogene succession into five major 2nd order depositional sequences, separated by four major depositional sequence boundaries (SB1, SB2, SB3 and SB4). The Upper Cretaceous-Palaeogene succession in the East Bahariya is dividedinto 17 systems tracts. These systems tracts are: 7 System tracts of probable Cenomanian age, (the sequence stratigraphic framework as well as the cycles and system tracts of the Cenomanian Bahariya Formation match well with thoseof CATUNEANUet al., 2006); 4 System tracts of Turonianage, 2 System tracts of Campanian-Maastrichtian ageand 4 System tracts of Eocene age.</p

Effects of major and trace elements from the El Kahfa ring complex on fish: Geological, physicochemical, and biological approaches

The alkaline rocks are known for enriching rare lithophilic elements, including lithium, uranium, and tin, which negatively impact aquatic life. This study offers an intensive investigation of the influence of alkaline rocks on Nile Tilapia (Oreochromis niloticus). The variation in blood profile, the induction of antioxidant enzymes, morphological erythrocyte, and histological structure have been conducted for the fish after 15 days of exposure to alkaline rocks powder with a dose of 100 μg/L. As a result, there was a pronounced decrease in blood profiles, such as platelets and white blood cell counts. There was a failure in the liver and kidney functions. Moreover, it shows an increase in superoxide dismutase (SOD) and catalase (CAT) activities as antioxidant biomarkers. Also, exposure to alkaline rocks induced DNA mutation and erythrocyte distortion. We concluded that the bulk alkaline rocks induced changes in the hemato-biochemical and antioxidant parameters of Nile tilapia. Additionally, exposure to bulk alkaline rock compounds also caused poikilocytosis and nuclear abnormalities of RBCs. This draws our attention to the seriousness of climatic changes, the erosion of rocks, and their access to water

Synthesis of quinone-based heterocycles of broad-spectrum anticancer activity

A synthesis of benzo[e][1,2,4]triazines and 1,2,4-triazolospiro[4,5]deca-2,6,9-trien-8-ones has been developed from reactions of amidrazones with 2-chloro-1,4-benzoquinone in EtOAc containing 0.5 mL of piperidine. This highly regioselective and one-pot process provided rapid access to 1,2,4-triazolospiro[4,5]deca-2,6,9-trien-8-ones (60%-70%) and benzo[e][1,2,4]triazines (11%-18%). On reacting amidrazones with 5-hydroxy-1,4-naphthoquinone in an EtOAc/piperidine mixture, the reaction proceeded to give 5-hydroxy-2-(piperidin-1-yl)naphthalene-1,4-dione. The structures of the isolated products were proved by infrared, NMR (2D-NMR), mass spectra, and elemental analyses in addition to X-ray structure analysis. The reaction mechanisms are discussed. The anticancer screening of selected compounds showed broad-spectrum anticancer activity against most melanoma cancer cell lines, ovarian cancer OVCAR-3, central nervous system cancer SF-295 and U251, non-small cell lung cancer NCI-H23, renal cancer SN12C, and colon cancer HCT-15 and HCT-116. The selected compounds exhibited moderate to weak anticancer activity to other cell lines.Peer reviewe

Regioselective formation of 1,2,4-triazoles by the reaction of amidrazones in the presence of diethyl azodicarboxylate and catalyzed by triethylamine

A general method for the synthesis of 1,3,5-trisubstituted 1,2,4-triazoles has been developed from reaction of amidrazones with ethyl azodicarboxylate and triethylamine (Mitsunobu reagent) in EtOH. This highly regioselective one-pot process provides rapid access to highly diverse triazoles. The reaction was explained, based on Mitsunobu reagent oxidizing ethanol to acetaldehyde, which would then react with amidrazones to give the substituted 3-methyltriazoles. A [2 + 3] cycloaddition reaction between two oxidized forms of amidrazones produced the second type of triazoles. X-ray structure analyses proved the structure of each type of product. [GRAPHICS] .Peer reviewe

A recent look for the implication and attitude of practicing female genital mutilation in upper Egypt: a cross sectional study

Background: Female genital mutilation (FGM) was defined as the partial or total removal of the female external genitalia for non-medical reasons The Demographic and Health Survey in Egypt in 2000 showed that 97% of married women included in the survey had experienced female genital mutilation.Methods: This is a cross sectional study to evaluate the current prevalence of FGM, current attitude of our society towards it after illegalization of it as a cross sectional survey of Upper Egypt. The most important point in this study is our evaluation of intention of these women whom exposed to FGM toward mutilation of their daughters or not and reasons for that. Statistical analysis was done using SPSS software version 21.Results: The study included 1175 women, from whom 89.1% were circumcised. Type 1 FGM was the most prevalent type practiced in about 58% of participants. Immediate complications occurred in 42.5% of women. Primary hemorrhage during circumcision was the most commonly reported immediate complication among 38.5% of them. Sexual problems were found in 40.5% of participants. Sixty-four women reported occurrence of hepatitis virus infection after the procedure. Moreover, 44 women were suffered from infertility and 72 women had an episode or chronic PID. Women who intend to circumcise their daughters are mostly those coming from rural areas (p=0.000) and housewives (p=0.000). Most of women (45.8%) who have the intent to circumcise their daughters claiming that it is religious based.Conclusions: The prevalence of FGM did not differ between urban and rural or between house wives and employee, lastly did not differ between different educational levels as most of them were encourage it thinking that it is of traditional, religious base and protect the girl from any abnormal sexual excitation. The women who intent not circumcise their daughters were from low educational level in its highest percentage and this was explained by occurrence of higher percentage of complications in spite of the highest percentage of operator was physician

Synthesis of quinone-based heterocycles of broad-spectrum anticancer activity

A synthesis of benzo[e][1,2,4]triazines and 1,2,4-triazolospiro[4,5]deca-2,6,9-trien-8-ones has been developed from reactions of amidrazones with 2-chloro-1,4-benzoquinone in EtOAc containing 0.5 mL of piperidine. This highly regioselective and one-pot process provided rapid access to 1,2,4-triazolospiro[4,5]deca-2,6,9-trien-8-ones (60%–70%) and benzo[e][1,2,4]triazines (11%–18%). On reacting amidrazones with 5-hydroxy-1,4-naphthoquinone in an EtOAc/piperidine mixture, the reaction proceeded to give 5-hydroxy-2-(piperidin-1-yl)naphthalene-1,4-dione. The structures of the isolated products were proved by infrared, NMR (2D-NMR), mass spectra, and elemental analyses in addition to X-ray structure analysis. The reaction mechanisms are discussed. The anticancer screening of selected compounds showed broad-spectrum anticancer activity against most melanoma cancer cell lines, ovarian cancer OVCAR-3, central nervous system cancer SF-295 and U251, non-small cell lung cancer NCI-H23, renal cancer SN12C, and colon cancer HCT-15 and HCT-116. The selected compounds exhibited moderate to weak anticancer activity to other cell lines