484 research outputs found
Recycling of mill scale in sintering process
This investigation deals with the effect of replacing some amount of Baharia high barite iron ore concentrate by mill scale waste which was characterized by high iron oxide content on the parameters of the sintering process., and investigation the effect of different amount of coke breeze added on sintering process parameters when using 5% mill scale waste with 95% iron ore concentrate. The results of this work show that, replacement of iron ore concentrate with mill scale increases the amount of ready made sinter, sinter strength and productivity of the sinter machine and productivity at blast furnace yard. Also, the increase of coke breeze leads to an increase the ready made sinter and productivity of the sintering machine at blast furnace yard. The productivity of the sintering machine after 5% decreased slightly due to the decrease of vertical velocity
Outlier detection in 2 × 2 crossover design using Bayesian framework
We consider the problem of outlier detection method in 2×2 crossover design via Bayesian framework. We study the problem of outlier detection in bivariate data fitted using generalized linear model in Bayesian framework used by Nawama. We adapt their work into a 2×2 crossover design. In Bayesian framework, we assume that the random subject effect and the errors to be generated from normal distributions. However, the outlying subjects come from normal distribution with different variance. Due to the complexity of the resulting joint posterior distribution, we obtain the information on the posterior distribution from samples by using Markov Chain Monte Carlo sampling. We use two real data sets to illustrate the implementation of the method
Green Technology Policy as a Driver for Change Sustainability Practices among the Community in Melaka
The suggestion for people to change their minds towards a developed society in line with the idea of implementing green technology urban development is a necessity to achieve sustainable development. Therefore, this study attempts to analyze the issues related to the need to change society’s practices so that society is able to face the cultural environment of society based on green technology towards sustainability. This study uses a quantitative method that is using by a questionnaire instrument involving a total of 308 respondents. The results of the analysis found that those living in areas involved with green technology were higher their awareness towards green lifestyle compared to communities outside the green technology declaration area. In general, there are various challenges in the implementation of green technology urban development in Melaka, especially in changing the lifestyle of the community towards the ideology of sustainable development based on green technology
Crude date syrup as fermentation medium for biosurfactant production by Natrialba sp. Strain E21
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Pharmaceutical analysis and in-vitro aerodynamic characterisation of inhaled theophylline formulations containing drug particles prepared by supercritical fluid processing. Chromatographic, spectroscopic, and thermal analysis of micron-sized theophylline particles prepared by supercritical fluid technology and in-vitro evaluation of their performance as inhaled dry powder formulations.
The aim of this work is to study the in-vitro aerodynamic performance of a new inhaled theophylline formulation prepared by supercritical fluids technique.
For the analysis of the output from the in-vitro tests (and further in-vivo tests) a new, fast, sensitive high performance liquid chromatographic (HPLC) method was developed and validated for the determination of theophylline and other related derivatives in aqueous and urine samples using new packing materials (monolithic columns). These columns achieve efficient separation under lower backpressure and shorter time comparing to other traditionally or newly introduced C18 columns.
Solution enhanced dispersion by supercritical fluid (SEDS) process has been applied for the production of anhydrous theophylline as pure crystals in the range 2-5 ¿m to be used as new inhaled dry powder formulation for asthma. Fifteen theophylline samples have been prepared under different experimental conditions.
The drug produced by this method has been subject to a number of solid-phase analytical procedures designed to establish the crystal structure [X-ray powder diffraction (XRPD)], the structure and conformation [(FTIR), Fourier-transform Raman spectroscopy (FT-Raman)], and the morphology and particle size [scanning electron microscope (SEM)]. While, thermal gravimetric analysis (TGA), and differential scanning calorimetry (DSC) have been used to monitor any phase transition or polymorphic changes after processing. All these analytical techniques gave a satisfactory indication of the solid-state chemistry of the processed particles and assess the development of new inhalation product.
The performance of inhaled SEDS theophylline with or without a carrier was evaluated using the developed HPLC method. Three samples having different particle sizes were selected out of the prepared powders by SEDS technique to be tested. The dose sampling unit and the Anderson Cascade Impactor were used to determine the in-vitro emitted dose and the deposition profiles of SEDS samples, respectively. The effect of different inhalation flows was studied using two different flows 28.3, and 60 L min-1 with 4 L inhalation volume. Different DPI devices were investigated in this study; Easyhaler® and Spinhaler®. The particle size has an important effect on the aerodynamic behaviour and deposition profile of inhaled drug, the smaller the particles the greater the total lung deposition. The presence of a carrier improves the respirable fraction for all the tested formulations.Egyptian Ministry of Higher Educatio
Production of single cell protein from organic whey using kluyveromyces fragilis and candida kefyr strains
Development and evaluation of polyherbal formulation for memory enhancement: study on its antioxidant properties and synergistic effects
Centella asiatica, Piper sarmentosum and Morinda citrifolia is well-known for their memory enhancement contribution from traditional practices as well as recent researches. However, all three herbs are utilized individually and never mixed together. The nutrient data on the synergistic effect on all three herbs remain scarce. The aims of this research project were to apply Simplex-centroid mixture design in describing the study for the effect of polyherbal formulation on antioxidants properties and its synergistic effects. Based on results obtained, there was a significant difference in antioxidant properties of the polyherbal formulation. The results show the polyherbal formulation 3 and 13 (M. citrifolia only) has the highest antioxidant capacity when being tested with total phenolic content (TPC) (210.10 and 209.12 μg GAE/mL respectively) and 2,2-diphenyl-1- picrylhydrazyl (DPPH) (42.94 and 37.77%) assays. Contradict to this result, the highest in total flavonoid content (TFC) and 2,2-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) for describing antioxidant properties are formulations 1 and 11 (C. asiatica only). The TPC for formulation 1 and 11 are 479.8 μg RE/mL and 470 μg RE/mL respectively while ABTS radical inhibition for formulation 1 and 11 are 64.53% and 60% respectively. For ferric reducing ability of plasma (FRAP) assay, formulation 7 (2.11 μg FSE/mL) is the highest which have 1:1:1 ratio of each herb. In addition, TPC, TFC, and DPPH assays showed high antioxidant activities when only single herbs were added into the formulation. Meanwhile, ABTS and FRAP are prone to binary polyherbal formulation. Hence, this study showed an antagonism effect instead of synergistic effect since single formulation exhibited the highest for TPC, TFC and DPPH. All tests gave the lowest antioxidant properties when the mix was ternary polyherbal formulation
A novel suture button construct for acute ankle syndesmotic injuries; A prospective clinical and radiological analysis
Background: The importance of the syndesmosis in ankle stability is well recognized. Numerous means of fixation have been described for syndesmotic injuries including the suture button technique. Significant cost limits the use the commercially available options. We, therefore, designed a cheap and readily available alternative construct. We aim to assess the results of using a novel suture-button construct in treatment of syndesmotic ankle injuries. Methods: Fifty-two patients (34 males and 18 females) fulfilled our inclusion/exclusion criteria. Five patients were lost to follow-up. The remaining 47 patients were successfully followed up for a minimum of 24 months. The pre and post-surgery American Orthopedic Foot and Ankle Society scores (AOFAS) together with reported complications and post-operative radiological analysis were assessed. In this innovative construct, we utilized polyester braided surgical sutures jointly with double mini two- holed plates, a No.2 polygalactin 910 suture, a 4 mm drill bit, together with a 15 cm long suture needle with slotted end. This technique was supported with the use of the image intensifier. Results: The AOFAS score improved significantly from a mean of 32.4 to 94.2 (P < 0.004). Radiologically, the medial clear space (MCS), tibio-fibular clear space (TFCS) (P=0.05) and tibio-fibular overlap (TFO) measurements showed a significant improvement postoperatively (P=0.02). Patients reported good satisfaction rates with a 96% success rate (95% CI: 94.0% to 99.3%). Conclusion: We have observed that this low cost suture button construct is a simple, safe and cost effective treatment option for acute syndesmotic injuries
Assessment of Influential Causes of Construction Project Delay in Malaysian Private Housing from Developer’s Viewpoint
Project delay in the construction industry is a universal or large-scale
observable fact affecting not only the construction industry but the overall economy of
countries too. The objective of this study is to evaluate and identify the causes and
consequences of project delays in the private housing development projects in Malaysia
and the remedies that can minimize these delays. An online questionnaire survey has
been carried out to collect the data and this included 76 respondents from multiple
developers’ companies around Malaysia. From the survey, a total of 28 causes and 6
consequences of project delays had been identified from four different factors of delays;
such as client factors, consultant factors, contractor factors and external factors, by which
the contractor factor being the major contributor to this problem.The top ten causes of the
delays are due to weather conditions, poor site conditions, poor site management,
incomplete documents, lack of experience, financial problems, contract modifications,
delay in approving of major variations, contractor coordination problem with other parties
and construction mistakes and defective works. The consequences of the delays would
contribute to time overrun, cost overrun, different in opinions, negotiations, legal actions
and total abandonment
Sensitivity Analysis of Cryogenic Cooling on Machining of Magnesium Alloy AZ31B-O
Improving the corrosion resistance of magnesium alloys has gained special focus in recent years, and cryogenic machining has been one of the successfully used techniques. The current study presents a sensitivity analysis of cryogenic cooling effects on process mechanics, when cutting AZ31B-O magnesium alloy. Finite element modelling was used to simulate orthogonal cutting of AZ31B-O under dry and cryogenic conditions, where different parameters (cutting forces, temperatures, shear angle, chip compression ratio and plastic deformation) were investigated. Also, orthogonal cutting tests were performed on a CNC lathe, under dry and cryogenic conditions, where cryogenic cooling was applied to the clearance side using an LN2 jet
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