123 research outputs found
Fault tree analysis for system modeling in case of intentional EMI
The complexity of modern systems on the one hand and the rising threat of intentional electromagnetic interference (IEMI) on the other hand increase the necessity for systematical risk analysis. Most of the problems can not be treated deterministically since slight changes in the configuration (source, position, polarization, ...) can dramatically change the outcome of an event. For that purpose, methods known from probabilistic risk analysis can be applied. One of the most common approaches is the fault tree analysis (FTA). The FTA is used to determine the system failure probability and also the main contributors to its failure. In this paper the fault tree analysis is introduced and a possible application of that method is shown using a small computer network as an example. The constraints of this methods are explained and conclusions for further research are drawn
Magnetospectroscopy of symmetric and anti-symmetric states in double quantum wells
The experimental results obtained for the magneto-transport in the
InGaAs/InAlAs double quantum wells (DQW) structures of two different shapes of
wells are reported. The beating-effect occurred in the Shubnikov-de Haas (SdH)
oscillations was observed for both types of the structures at low temperatures
in the parallel transport when magnetic field was perpendicular to the layers.
An approach to the calculation of the Landau levels energies for DQW structures
was developed and then applied to the analysis and interpretation of the
experimental data related to the beating-effect. We also argue that in order to
account for the observed magneto-transport phenomena (SdH and Integer Quantum
Hall effect), one should introduce two different quasi-Fermi levels
characterizing two electron sub-systems regarding symmetry properties of their
states, symmetric and anti-symmetric ones which are not mixed by
electron-electron interaction.Comment: 20 pages, 20 figure
Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB
OBJECTIVE:
Hypoxia affects body iron homeostasis; however, the underlying mechanisms are incompletely understood.
DESIGN:
Using a standardised hypoxia chamber, 23 healthy volunteers were subjected to hypoxic conditions, equivalent to an altitude of 5600 m, for 6 h. Subsequent experiments were performed in C57BL/6 mice, CREB-H knockout mice, primary hepatocytes and HepG2 cells.
RESULTS:
Exposure of subjects to hypoxia resulted in a significant decrease of serum levels of the master regulator of iron homeostasis hepcidin and elevated concentrations of platelet derived growth factor (PDGF)-BB. Using correlation analysis, we identified PDGF-BB to be associated with hypoxia mediated hepcidin repression in humans. We then exposed mice to hypoxia using a standardised chamber and observed downregulation of hepatic hepcidin mRNA expression that was paralleled by elevated serum PDGF-BB protein concentrations and higher serum iron levels as compared with mice housed under normoxic conditions. PDGF-BB treatment in vitro and in vivo resulted in suppression of both steady state and BMP6 inducible hepcidin expression. Mechanistically, PDGF-BB inhibits hepcidin transcription by downregulating the protein expression of the transcription factors CREB and CREB-H, and pharmacological blockade or genetic ablation of these pathways abrogated the effects of PDGF-BB toward hepcidin expression.
CONCLUSIONS:
Hypoxia decreases hepatic hepcidin expression by a novel regulatory pathway exerted via PDGF-BB, leading to increased availability of circulating iron that can be used for erythropoiesis
The genus Gautieria (Gomphales) in Europe and the Mediterranean Basin : a morphological and phylogenetic taxonomic revision
Type material and additional collections of 11 taxa of Gautieria described in Europe and North Africa have been studied, namely G. dubia , G. graveolens , G. morchelliformis var. globispora , G. morchelliformis var. magnicellaris , G. morchelliformis var. morchelliformis , G. morchelliformis var. stenospora , G. otthii , G. pseudovestita , G. retirugosa , G. trabutii and G. villosa . At the same time, morphological and genetic studies on recent and herbarium collections from several European countries have been carried out. This enabled clarification of sections within Gautieria and differentiation of 28 taxa, of which 21 are new to science. However, the deeper relationships and nomenclature changes related to the phylogenetic position of the genus Gautieria within Gomphaceae will not be addressed in this study because they would require a more complete molecular analysis together with that of related genera, e. g., Gomphus , Turbinellus , and the four subgenera of Ramaria . In addition, a lectotype for G. villosa var. villosa and reference specimens for G. graveolens and G. morchelliformis var. morchelliformis are selected, and the new combination G. morchelliformis var. dubia is proposed. Detailed descriptions, macro- and microphotographs and distribution maps of all taxa are provided, as well as extensive information on their ecology, chorology and phylogeny. A key is included to facilitate identification of taxa
Parallel magnetotransport in multiple quantum well structures
The results of investigations of parallel magnetotransport in AlGaAs/GaAs and
InGaAs/InAlAs/InP multiple quantum wells structures (MQW’s) are presented in this paper.
The MQW’s were obtained by metalorganic vapour phase epitaxy with different shapes of QW,
numbers of QW and levels of doping. The magnetotransport measurements were performed in wide
region of temperatures (0.5–300 K) and at high magnetic fields up to 30 T (B is perpendicular and
current is parallel to the plane of the QW). Three types of observed effects are analyzed: quantum
Hall effect and Shubnikov—de Haas oscillations at low temperatures (0.5–6 K) as well as
magnetophonon resonance at higher temperatures (77–300 K)
Fungal root endophyte associations of plants endemic to the Pamir Alay Mountains of Central Asia
The fungal root endophyte associations of 16 species from 12 families of plants endemic to the Pamir Alay Mountains of Central Asia are presented. The plants and soil samples were collected in Zeravshan and Hissar ranges within the central Pamir Alay mountain system. Colonization by arbuscular mycorrhizal fungi (AMF) was found in 15 plant species; in 8 species it was of the Arum type and in 4 of the Paris type, while 3 taxa revealed intermediate arbuscular mycorrhiza (AM) morphology. AMF colonization was found to be absent only in Matthiola integrifolia, the representative of the Brassicaceae family. The AM status and morphology are reported for the first time for all the species analyzed and for the genera Asyneuma, Clementsia, and Eremostachys. Mycelia of dark septate endophytes (DSE) accompanied the AMF colonization in ten plant species. The frequency of DSE occurrence in the roots was low in all the plants, with the exception of Spiraea baldschuanica. However, in the case of both low and higher occurrence, the percentage of DSE root colonization was low. Moreover, the sporangia of Olpidium spp. were sporadically found inside the root epidermal cells of three plant species. Seven AMF species (Glomeromycota) found in the trap cultures established with soils surrounding roots of the plants being studied were reported for the first time from this region of Asia. Our results provide information that might well be of use to the conservation and restoration programmes of these valuable plant species. The potential application of beneficial root-inhabiting fungi in active plant protection projects of rare, endemic and endangered plants is discussed
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