226 research outputs found
Managing technological uncertainty in science incubation:A prospective sensemaking perspective
This paper focuses on the adaption challenge that confronts the top management team (TMT) of science incubators in situations of substantial technological uncertainty. To do that, we draw on the three-year longitudinal analysis of a major bioscience catalyst in the UK. Through the lens of âprospective sensemakingâ, we follow the TMT as they work with stakeholders in their ecosystem to make sense of a significant technological shift: the convergence of life sciences, IT and other sciences in the health care environment. Our analysis reveals how prospective sensemaking resulted in the launch of a new strategy to exploit these emerging opportunities. However, stakeholdersâ increasingly fragmented interpretation of the term convergence and the anticipation of legitimacy challenges in the wider ecosystem resulted in the repositioning of the incubator. Our findings contribute to extant research on science incubation. In particular, the paper sheds light on the complex interactions of incubator TMTâs with stakeholders in situations of technological change and uncertainty. Moreover, responding to technological change does not only affect the structural conditions of an incubator. Rather, it may also require changes to the positioning of the incubator in order to maintain legitimacy in the wider ecosystem. The paper also suggests managerial as well as policy level implications
Multiple Interactions and the Structure of Beam Remnants
Recent experimental data have established some of the basic features of
multiple interactions in hadron-hadron collisions. The emphasis is therefore
now shifting, to one of exploring more detailed aspects. Starting from a brief
review of the current situation, a next-generation model is developed, wherein
a detailed account is given of correlated flavour, colour, longitudinal and
transverse momentum distributions, encompassing both the partons initiating
perturbative interactions and the partons left in the beam remnants. Some of
the main features are illustrated for the Tevatron and the LHC.Comment: 69pp, 33 figure
Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk
Beta cell glucose sensitivity is decreased by 39% in non-diabetic individuals carrying multiple diabetes-risk alleles compared with those with no risk alleles
Gender gap in parental leave intentions: Evidence from 37 countries
This is the final version. Available from Wiley via the DOI in this record.âŻDespite global commitments and efforts, a gender-based division of paid and unpaid work persists. To
identify how psychological factors, national policies, and the broader sociocultural context contribute
to this inequality, we assessed parental-leave intentions in young adults (18â30years old) planning to
have children (N = 13,942; 8,880 identified as women; 5,062 identified as men) across 37 countries that
varied in parental-leave policies and societal gender equality. In all countries, women intended to take
longer leave than men. National parental-leave policies and womenâs political representation partially
explained cross-national variations in the gender gap. Gender gaps in leave intentions were paradoxically
larger in countries with more gender-egalitarian parental-leave policies (i.e., longer leave available to
both fathers and mothers). Interestingly, this cross-national variation in the gender gap was driven by
cross-national variations in womenâs (rather than menâs) leave intentions. Financially generous leave
and gender-egalitarian policies (linked to menâs higher uptake in prior research) were not associated with
leave intentions in men. Rather, menâs leave intentions were related to their individual gender attitudes.
Leave intentions were inversely related to career ambitions. The potential for existing policies to foster
gender equality in paid and unpaid work is discussed.SSHRC Insight Development GrantSSHRC Insight GrantEconomic and Social Research CouncilState Research AgencyGuangdong 13th-five Philosophy and Social Science Planning ProjectNational Natural Science Foundation of ChinaSwiss National Science FoundationSwiss National Science FoundationCenter for Social Conflict and Cohesion StudiesCenter for Intercultural and Indigenous ResearchSSHRC Postdoctoral FellowshipSlovak Research and Development AgencySwiss National Science FoundationCanada Research ChairsSocial Sciences and Humanities Research Council of CanadaOntario Ministry of Research and InnovationHSE University, RFFaculty of Arts, Masaryk Universit
An Isolated Stellar-Mass Black Hole Detected Through Astrometric Microlensing
We report the first unambiguous detection and mass measurement of an isolated stellar-mass black hole (BH). We used the Hubble Space Telescope (HST) to carry out precise astrometry of the source star of the long-duration (t_E ~ 270 days), high-magnification microlensing event MOA-2011-BLG-191/OGLE-2011-BLG-0462, in the direction of the Galactic bulge. HST imaging, conducted at eight epochs over an interval of six years, reveals a clear relativistic astrometric deflection of the background star's apparent position. Ground-based photometry shows a parallactic signature of the effect of the Earth's motion on the microlensing light curve. Combining the HST astrometry with the ground-based light curve and the derived parallax, we obtain a lens mass of 7.1 +/- 1.3 M_Sun and a distance of 1.58 +/- 0.18 kpc. We show that the lens emits no detectable light, which, along with having a mass higher than is possible for a white dwarf or neutron star, confirms its BH nature. Our analysis also provides an absolute proper motion for the BH. The proper motion is offset from the mean motion of Galactic-disk stars at similar distances by an amount corresponding to a transverse space velocity of ~45 km/s, suggesting that the BH received a modest natal 'kick' from its supernova explosion. Previous mass determinations for stellar-mass BHs have come from radial-velocity measurements of Galactic X-ray binaries, and from gravitational radiation emitted by merging BHs in binary systems in external galaxies. Our mass measurement is the first ever for an isolated stellar-mass BH using any technique
Managing technological uncertainty in science incubation: a prospective sensemaking perspective
Biogenic Amine-Sensitive Membrane Electrodes Using the Hydrogen Bond-Forming Ability of Solvent Mediators.
New Convenient Dissolution of Iron-Rhodium Alloys Using Hydrochloric Acid Containing a Small Amount of Nitric Acid without Heating for an ICP-AES Analysis.
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