Identifying major traits of personality towards life satisfaction among married students

This study intends to identify major traits of personality that affect life satisfaction among married participants in Universiti Teknologi Malaysia. Random sampling was used to select the participants of this study. The sample consists of 158 married students. In order to find this relation, Satisfaction with Life Scale questionnaire, and Tajma Personality Profile questionnaire (TPP2) were used. The results show that major traits such as self-confidence, extrovert, and resiliency have strong effect on life satisfaction

The Effect of Group Counseling on the Quality of Life in Patients with Major Thalassemia Referred to the Thalassemia Treatment Center in Bushehr

Background and Objective: Major Thalassemia is the most common hereditary disease in the world and in Iran. The chronic nature of the disease and complications associated with clinical signs and protests of the disease and its treatment make multiple physical, psychological and social problems and effects on the quality of life in these patients. The aim of this study was to determine the effect of group counseling on quality of life in patients with thalassemia major. Materials and Methods: This study was a randomized controlled clinical trial. The total number of subjects included 62 patients with thalassemia major from thalassemia treatment center in the Bushehr in 2016, were randomly divided into two groups of 31 people of intervention and control. For intervention group, four sessions of group counseling in behavioral cognitive approach held in two weeks. The quality of life in patients in both groups evaluated before the intervention and one month after the intervention, using the SF-36 questionnaire. The results were analyzed by SPSS software version 23 at a significant level of 0.05. Results: The results of analytical tests showed that there was no statistically significant difference between the two groups in demographic variables (P > 0.05). However, the intervention group gained a significant increase in total score of quality of life and its sub-domains after counseling. (P < 0/001). Also, the difference between the mean total scores of quality of life and its sub-domains in the intervention and control groups was statistically significant (P < 0.001). Conclusion: This study showed that the treatment group counseling with cognitive behavioral approach significantly improves the quality of life in patients with Thalassemia major. Therefore it is recommended that this treatment helped to improve the quality of life in these patients. m

ارزیابی ریسک نسبی اثرات تحریکی در تراشکاران مواجهه یافته با میست مایعات فلزکاری منتخب از شهر تهران

Background and Objectives: Occupational exposure to metalworking fluid mist causes respiratory irritation. This study aimed to assess the relative risk of irritating effects in occupational exposure to metalworking fluids of lathe process. Materials and Methods: Sixty-five subjects exposed to oil mist as exposed group and 65 administrative staff of the same industry as control group were selected. Health and Safety Executive/Health and Safety Laboratory (HSE/HSL) questionnaire was used for irritating effects. The US National Institutes of Health and Safety (NIOSH) method 5026 was used to monitoring respiratory exposure to oil mist. We also calculated the relative risk of irritating symptoms using MedCalc software. The study was approved by the ethics committee and conducted with the consent of participants. Results: The mean time-weighted exposure to mineral oil mist in lathe workers was 7.10±3.49 mg/m3. The amount of throat irritation in machinists was significantly higher than the control group (p-value = 0.044).The relative risk of irritating effects in the eyes, nose, mouth and throat in machinists is slightly higher than control subjects (p-value = 0.05). Conclusion: In this study, the occupational exposure in 67% of lathe workers is higher than recommended exposure limit in Iran. Subjects by oil mists exposure represented a risk of irritating effects in the respiratory tract, especially the throat. For this reason, continuous assessment and control of exposure is are needed to reduce the risk of chronic diseases.زمینه و اهداف: مواجهه شغلی با میست مایعات فلزکاری باعث بروز اثرات تحریکی در مجاری تنفسی می‌گردد. هدف مطالعه حاضر ارزیابی ریسک نسبی اثرات تحریکی در مواجهه شغلی با میست مایعات فلزکاری در تراشکاری است. مواد و روش­ها: در این مطالعه 65 نفر از تراشکاران مواجهه یافته با میست روغن به‌عنوان گروه مواجهه و 65 نفر از کادر اداری همان صنعت به‌عنوان گروه کنترل انتخاب گردیدند. جهت بررسی اثرات تحریکی میست روغن از پرسشنامه آژانس ایمني، بهداشت و محیط‌زیست/آزمایشگاه ایمني و بهداشت HSE/HSL و جهت پایش میزان مواجهه تنفسی با میست روغن از روش 5026 انستیتو ملی ایمنی و بهداشت آمریکا (NIOSH) استفاده شد. میزان ریسک نسبی علائم تحریکی نیز با استفاده از نرم­افزار MedCalc محاسبه شد. مطالعه حاضر دارای تاییدیه کمیته اخلاق بوده و با کسب رضایت از شرکت­کنندگان انجام‌شده است. یافته­ ها: میانگین مواجهه وزنی-زمانی با میست روغن معدنی در کارگران تراشکاری 49/3 ± 10/7 میلی‌گرم در مترمکعب ارزیابی شد. تحریک حلق در ماشینکاران به‌طور معناداری بالاتر از گروه شاهد است (044/0 p-value=). ریسک نسبی عوارض تحریک در چشم، بینی، دهان و حلق در ماشینکاران اندکی بالاتر از افراد گروه شاهد محاسبه شد (05/0 p-value=). نتیجه‌گیری: در این مطالعه مواجهه شغلی در 67٪ از کارگران تراشکاری بالاتر از حد توصیه‌شده در ایران است. ریسک اثرات تحریکی در مجاری تنفسی به‌ویژه حلق در ماشینکاران دارای مواجهه با میست مایعات فلزکاری نسبت به گروه کنترل بالاتر است. به همین دلیل ضرورت ارزیابی و کنترل مداوم مواجهه در جهت کاهش ریسک و پیشگیری از بروز بیماری‌های مزمن مدنظر قرار دارد

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly

Sulfate Adsorption on Iron Nanocomposites on Graphene Oxide and Activated Carbon Beds

This study is an experimental investigation of sulfate removal efficiency using iron nanocomposites on graphene oxide and activated carbon beds. The graphene oxide used was synthesized according to the Hummer method during which process graphene oxide and activated carbon were added. The effects of various parameters including adsorbent content, pH, and contact time on adsorption were investigated. Furthermore, the data were subjected to kinetic studies. Results revealed that the highest absorption rates of 84% and 62% were achieved for iron on the graphene oxide and activated carbon beds, respectively, when 0.06 g of the adsorbent was used at pH =11 over a contact time of 9 hours. It was also found that the kinetic pseudo-second-order model best fit the data. Finally, the results indicated that the two environmentally-friendly adsorbents have a good potential for removing sulfate from aqueous solutions

Successful management of multiple small bowel perforations due to polyarteritis nodosa

Classic Polyarteritis nodosa (PAN)) is a medium-sized vessel vasculitis that usually occurs in middle-aged men. One of the dramatic manifestations of PAN that requires surgical intervention is multiple small bowel perforations. Many studies have reported a high rate of mortality in PAN due to acute abdominal complications. We report here the case of multiple small bowel perforations in a 22-year-old man, who presented with an acute abdomen, and eventually, PAN was diagnosed. In our case, PAN led to multiple small bowel perforations and diffuse patchy necrosis. All perforations were primarily repaired and corticosteroids were prescribed. Using corticosteroid in patients with abdominal sepsis is injurious; however, laparostomy is the method we suggest, to achieve the purpose, including prevention of a short bowel and infection control. Our patient was discharged, well, after 48 days of hospitalization and referred to a rheumatologist

Prevalence of Fecal Outlet Obstruction and Its Predisposing Factors in Women Aged 40 years and Older: An Epidemiological Study

Objectives: The aim of this study is to determine the prevalent of Fecal Outlet Abstract&nbsp; Obstruction (FOO) and associated risk factors in women aged 40 and older. Methods & Materials: In this cross sectional study, a total of 800 women were&nbsp; randomly selected via cluster sampling among residents of area zone 17 of Tehran Health Management and were interviewed at home. Data was analyzed using Chi-square and Fisher exact Economics tests. Results: Prevalence for FOO cases was mild 36.5% (95% CI, 33&ndash;39%), medium 8%(95% CI, 6&ndash;10%) and acute 0.5% (95% CI, 0.01&ndash;0.9%) which was only associated with age increase (P=0.006). There is a significant relationship between Physical activity and morbidity of FOO (P=0.004). FOO was associated with depressive and anxiety disorders, osteoarthritis, osteoporosis, diabetes, chronic, cough, and chronic inflammatory bowel disease (P<0.005). Conclusion: This study underscores the prevalence rate of FOO symptoms and its underlying factors. It also considers lack of knowledge about this hidden&nbsp; problem and its protective factors among women in&nbsp; recommends further research to determine effective strategies for prevention education, screening and early treatment to promote women's health and quality of life

Successful Surgical Treatment of Intractable Post-Radiation Rectal Bleeding

Patients will typically present symptoms of chronic post-radiation colitis and proctitis 8–12 months after finishing their treatment. Endoscopic methods play the main role the treatment of bleeding caused by post-radiation colitis and proctitis. Surgical treatment is required for remained approximately 10% of patients. Here we present a 64 year old female with metastatic breast cancer, who was referred to us for intractable rectal bleeding. Total colonoscopy and rigid rectosigmoidoscopy revealed proctitis, rectal and sigmoidal telangiectasis, multiple necrotic ulcers between 15 to 30 cm from the anal verge, and also huge ishemic ulcer with patchy necrotic areas about 10 cm from the anal verge. This abnormal irradiated part was resected and then mucosectomy of the remnant rectum, both transabdominally and transanally was done. We performed pull-through technique of normal proximal colon to anal region through the remnant rectal wall and finally did coloanal anastomosis. Diverting stoma was not made because of anastomosis in anal region. With this technique we can achieve benefits such as avoidance of harsh dissection in a frozen pelvis and its consequences, we can avoid intra-abdominal anastomosis, there is no need to a diverting stoma and, most important of all, definite bleeding control

A cross-sectional survey of quality of life in colostomates: a report from Iran

<p>Abstract</p> <p>Background</p> <p>Considering the complications that colostomies may cause, patient self-assessments of their social, emotional, physical, sexual and functional conditions may help their surgeons to evaluate the impact of their interventions or use supplementary methods to maintain patient functional status or decrease its loss to the minimum level. The aim of this study was to evaluate the Quality of Life in Iranian patients with colostomies and to compare the age and gender differences among them.</p> <p>Method</p> <p>This cross-sectional study was conducted from 2009 to 2010 to evaluate the quality of life of 96 patients who had undergone surgery for rectal cancer and had permanent colostomies. The European Organization for Research and Treatment of Cancers Quality of Life Questionnaire (EORTC QLQ)-C30 and the EORTC QLQ-CR38 were used to assess patient Quality of Life.</p> <p>Results</p> <p>The mean scores for the functional subscales were as follows: Physical Function, 70.9 (±2.2); Role Function, 68.4 (±2.6); Emotional Function, 56.9 (±2.7); Cognitive Function, 68.7 (± 2.6); and Social Function, 64.2 (±3.3). The EORTC questionnaires showed significant differences between males and females. Males had better body image scores. Sexual Function and Sexual Enjoyment were impaired in both males and females, but males had significantly higher scores and better roles in Physical and Sexual Functions. More sexual enjoyment problems in older ages were observed in both males and females.</p> <p>Conclusion</p> <p>Having a colostomy was associated with a high level of emotional and sexual function impairment. The differing challenges between males and females should encourage us to design sex-specific interventions that improve the quality of life in this group of patients.</p