Institutional reforms in irrigation sector of Punjab, Pakistan: Proceedings of Workshop held at Faisalabad Serena on 10-11 February 2000

Institution building / Irrigated farming / Irrigation management / Participatory management / Farmer participation / Farmers' associations / Pakistan / Punjab / Hakra

Institutional reforms in irrigation sector of Punjab, Pakistan: Proceedings of Workshop held at Faisalabad Serena on 10-11 February 2000

Institution building / Irrigated farming / Irrigation management / Participatory management / Farmer participation / Farmers' associations / Pakistan / Punjab / Hakra

Lorentzian Wormholes in the Friedman-Robertson-Walker Universe

The metric of some Lorentzian wormholes in the background of the FRW universe is obtained. It is shown that for a de Sitter space-time the new solution is supported by Phantom Energy. The wave equation for a scalar field in such backgrounds is separable. The form of the potential for the Schr\"{o}dinger type one dimensional wave equation is found.Comment: 7 page

Charged Particle Dynamics in the Field of a Slowly Rotating Compact Star

We study the dynamics of a charged particle in the field of a slowly rotating compact star in the gravitoelectromagnetic approximation to the geodesic equation . The star is assumed to be surrounded by an ideal, highly conducting plasma (taken as a magnetohydrodynamic fluid) with a stationary, axially symmetric electromagnetic field. The general relativistic Maxwell equations are solved to obtain the effects of the background spacetime on the electromagnetic field in the linearized Kerr spacetime. The equations of motion are then set up and solved numerically to incorporate the gravitational as well as the electromagnetic effects. The analysis shows that in the slow rotation approximation the frame dragging effects on the electromagnetic field are absent. However the particle is directly effected by the rotating gravitational source such that close to the star the gravitational and electromagnetic field produce contrary effects on the particle's trajectory.Comment: 10 pages, 6 figures in B & W PostScript Forma

Glycyrrhetinic acid and E.resveratroloside act as potential plant derived compounds against dopamine receptor D3 for Parkinson's disease: a pharmacoinformatics study

Parkinson’s disease (PD) is caused by loss in nigrostriatal dopaminergic neurons and is ranked as the second most common neurodegenerative disorder. Dopamine receptor D3 is considered as a potential target in drug development against PD because of its lesser side effects and higher degree of neuro-protection. One of the prominent therapies currently available for PD is the use of dopamine agonists which mimic the natural action of dopamine in the brain and stimulate dopamine receptors directly. Unfortunately, use of these pharmacological therapies such as bromocriptine, apomorphine, and ropinirole provides only temporary relief of the disease symptoms and is frequently linked with insomnia, anxiety, depression, and agitation. Thus, there is a need for an alternative treatment that not only hinders neurodegeneration, but also has few or no side effects. Since the past decade, much attention has been given to exploitation of phytochemicals and their use in alternative medicine research. This is because plants are a cheap, indispensable, and never ending resource of active compounds that are beneficial against various diseases. In the current study, 40 active phytochemicals against PD were selected through literature survey. These ligands were docked with dopamine receptor D3 using AutoDock and AutoDockVina. Binding energies were compared to docking results of drugs approved by the US Food and Drug Administration against PD. The compounds were further analyzed for their absorption, distribution, metabolism, and excretion-toxicity profile. From the study it is concluded that glycyrrhetinic acid and E.resveratroloside are potent compounds having high binding energies which should be considered as potential lead compounds for drug development against PD

Glycyrrhetinic acid and E.resveratroloside act as potential plant derived compounds against dopamine receptor D3 for Parkinson's disease: a pharmacoinformatics study

Parkinson’s disease (PD) is caused by loss in nigrostriatal dopaminergic neurons and is ranked as the second most common neurodegenerative disorder. Dopamine receptor D3 is considered as a potential target in drug development against PD because of its lesser side effects and higher degree of neuro-protection. One of the prominent therapies currently available for PD is the use of dopamine agonists which mimic the natural action of dopamine in the brain and stimulate dopamine receptors directly. Unfortunately, use of these pharmacological therapies such as bromocriptine, apomorphine, and ropinirole provides only temporary relief of the disease symptoms and is frequently linked with insomnia, anxiety, depression, and agitation. Thus, there is a need for an alternative treatment that not only hinders neurodegeneration, but also has few or no side effects. Since the past decade, much attention has been given to exploitation of phytochemicals and their use in alternative medicine research. This is because plants are a cheap, indispensable, and never ending resource of active compounds that are beneficial against various diseases. In the current study, 40 active phytochemicals against PD were selected through literature survey. These ligands were docked with dopamine receptor D3 using AutoDock and AutoDockVina. Binding energies were compared to docking results of drugs approved by the US Food and Drug Administration against PD. The compounds were further analyzed for their absorption, distribution, metabolism, and excretion-toxicity profile. From the study it is concluded that glycyrrhetinic acid and E.resveratroloside are potent compounds having high binding energies which should be considered as potential lead compounds for drug development against PD

Tingkat Kedinamisan Kelompok Wanita Tani dalam Mendukung Keberlanjutan Usaha Tanaman Obat Keluarga di Kabupaten Bogor, Jawa Barat

Penelitian ini bertujuan menganalisis tingkat dinamika kelompok mendukung keberlanjutan USAha tanaman obat keluarga dan menganalisis faktor-faktor kedinamisan kelompok yang berhubungan nyata dengan keberlanjutan USAha tanaman obat keluarga. Penelitian lapang dilakukan di Kelompok wanita tani Benteng Sejahtera dan Puring Desa Benteng Kecamatan Ciampea dan Kelompok wanita tani Anggrek Desa Babakan Kecamatan Dramaga Kabupaten Bogor mulai Agustus sampai dengan Oktober 2016. Populasi penelitian yaitu 62 orang yang mengembangkan USAha tanaman obat keluarga. Hasil penelitian ini yaitu 1) kelompok dalam mendukung keberlanjutan USAha tanaman obat keluarga secara keseluruhan cukup dinamis. 2) faktor-faktor yang berhubungan dengan keberlanjutan USAha tanaman obat keluarga diantaranya tingkat pendapatan keluarga berhubungan nyata negatif dengan aspek sosial, intensitas penyuluhan berhubungan nyata negatif dengan aspek sosial, keefektifan berhubungan nyata negatif dengan aspek sosial, maksud terselubung berhubungan nyata dengan aspek ekonomi