Remote monitoring of natural slopes. Insights from the first Terrestrial INSAR campaign In Vietnam

Il presente lavoro, realizzato nell'ambito di un progetto di ricerca finanziato dal Vietnamese Space Science & Technology Program, mostra i primi risultati di una campagna di monitoraggio da remoto della frana di Nam Dan (Vietnam settentrionale) dove, per la prima volta nel Paese, è stata utilizzata la tecnica dell'Interferometria SAR Terrestre (TInSAR). Tale tecnica si basa sull’utilizzo di un sensore radar installato su una piattaforma terrestre che trasmette il segnale nel campo delle microonde (banda Ku) e ne riceve gli echi di ritorno dai target riflettenti. Il sensore utilizzato è costituito da due antenne (una trasmittente e una ricevente) e si muove seguendo una traiettoria lineare lungo un binario. Grazie a questa tecnica è possibile effettuare da remoto il monitoraggio delle deformazioni del terreno, raggiungendo una precisione sub-millimetrica in condizioni ideali (ad es. breve distanza, alta riflettività, etc.). Le attività di monitoraggio sono state condotte nel villaggio di Nam Dan, dove una frana attiva con diverse evidenze geomorfologiche quali scarpate, crepe, contropendenze con ristagni d’acqua, abitazioni e beni pubblici gravemente danneggiati, costituisce una seria minaccia per la popolazione locale. L’area di Nam Dan (22°36'N; 104°29'E) si trova nella parte meridionale del distretto di Xin Man, in prossimità del confine tra Vietnam e Cina. Tale distretto, caratterizzato da un clima monsonico umido subtropicale, si estende su un'area di circa 582 km2ed è caratterizzato da una topografia complessa con catene montuose, pendii terrazzati e valli molto profonde con processi erosivi avanzati. Gli archivi locali riportano che in tale area, dal 2012 al 2016, si sono verificate 967 frane, principalmente durante l'estate in corrispondenza delle piogge monsoniche del sud-ovest. Secondo recenti indagini e osservazioni sul campo, la frana oggetto di studio, verificatasi nel luglio del 2012 in seguito a forti precipitazioni, può classificarsi come uno scivolamento traslativo di detrito e si estende su un'area di circa 12.000 m2 con una profondità media di circa 22,5 metri. Nell'agosto del 2013 la frana ha causato nuovi gravi danni a 5 abitazioni, al mercato comunale e alla strada provinciale n. 178 e rappresenta tutt’oggi un grave pericolo per la popolazione residente. Le attività di monitoraggio sono state effettuate tra agosto e dicembre 2019 attraverso un nuovo interferometro radar denominato Phoenix, che è stato utilizzato in una delle sue prime applicazioni sul campo. Il monitoraggio tramite Interferometria SAR Terrestre ha avuto l’obiettivo di controllare l’evoluzione del versante instabile ed ha portato alla realizzazione di mappe di spostamento e delle relative serie temporali, fornendo informazioni dettagliate sulla localizzazione e sui tassi di deformazione dei processi gravitativi di versante presenti. Sebbene nel periodo monitorato non siano state registrate deformazioni significative, l'utilizzo di questa tecnica di telerilevamento, insieme alla strumentazione a contatto precedentemente installata (inclinometri, piezometri, pluviometri) ed alle indagini sul campo, hanno contribuito a migliorare la conoscenza della frana di Nam Dan e la comprensione del suo cinematismo, con particolare riguardo all'evoluzione temporale delle deformazioni superficiali, anche tenendo conto delle condizioni meteorologiche locali. I risultati ottenuti durante la campagna di monitoraggio, in combinazione con i dati precedentemente acquisiti ed elaborati, confermano che il versante oggetto di studio è caratterizzato da fenomeni di instabilità gravitativa, che possono essere innescati da precipitazioni intense che solitamente avvengono nell’area durante la stagione estiva. In considerazione dei contesti ambientali dell'area, quali le severe condizioni climatiche e le aree impervie da percorrere in assenza di infrastrutture viarie adeguate, è stato posto l'accento sulle attività operative sul campo e sull'individuazione di soluzioni tecnologiche appropriate, che hanno rappresentato aspetti particolarmente sfidanti per il monitoraggio di fenomeni franosi tramite tecniche di telerilevamento.The present work, realized in the framework of a research project funded by the Vietnamese Space Science & Technology Program, shows the first insights of remote monitoring at the Nam Dan landslide (Northern Vietnam). The Terrestrial SAR Interferometry (TInSAR) technique was used for the first time in the Country.The activities were performed in Nam Dan village, where an active landslide with several geomorphological evidences as open cracks and scarps, severely damaged dwellings and public assets, constituting a serious hazard to the local inhabitants. The monitoring activities were carried out between August and December 2019 through a new TInSAR device called Phoenix which it was used for one of its first on-field applications. The Terrestrial SAR was aimed at creating displacement maps and related time series, providing detailed information on the location and deformation rate of the processes under investigation. The use of such a remote sensing technique, coupled with contact instrumentation (inclinometers, piezometers, rain gauge) and field surveys have contributed to improving the knowledge about the Nam Dan landslide and the understanding of its behaviour, with particular regard to the time evolution of deformations

Regularity of Edge Ideals and Their Powers

We survey recent studies on the Castelnuovo-Mumford regularity of edge ideals of graphs and their powers. Our focus is on bounds and exact values of $\text{ reg } I(G)$ and the asymptotic linear function $\text{ reg } I(G)^q$, for $q \geq 1,$ in terms of combinatorial data of the given graph $G.$Comment: 31 pages, 15 figure

Reproductive performance in sows in relation to Japanese Encephalitis Virus seropositivity in an endemic area

Japanese Encephalitis Virus (JEV) is considered an important reproductive pathogen in pigs. Most studies of the reproductive impact of JEV have been conducted in areas where the disease occurs in seasonal epidemics. In this study, the associations between seropositivity for JEV, measured with an IgG ELISA, and the number of piglets born alive and stillborn were investigated in a tropical area endemic for JEV in Vietnam. Sixty percent of sows from four farms in the Mekong delta of Vietnam were seropositive to JEV and the Odds Ratio for a sow being infected was highest (6.4) in sows above 3.5 years (95% confidence interval 2.2–18.3). There was an association between increasing Optical Density (OD) values from the ELISA and the number of stillborn piglets in sows less than 1.5 years, but no effect of seropositivity could be shown when all sows were studied. OD values had an effect (p = 0.04) on the number of piglets born alive in the statistical analysis only when interacting with the effect of the breeds. An increase in mean OD value of the herd was correlated (p < 0.0001) with an increase in the number of piglets born alive. In this study, there was evidence of a negative association between seropositivity for JEV and the reproductive performance only in sows less than 1.5 years in endemic areas. This could be explained by a year-round infection with the virus, which would lead to immunity in many gilts before their first pregnancy. This, in turn, may imply that JEV infection in pigs is of minor importance for the reproductive performance in endemic areas

Vaccine Effectiveness against Medically Attended Laboratory-Confirmed Influenza in Japan, 2011?2012 Season

The objective of this study was to estimate influenza vaccine effectiveness (VE) against medically attended, laboratoryconfirmed influenza during the 2011-2012 season in Japan using a test-negative case-control study design. The effect of cocirculating non-influenza respiratory viruses (NIRVs) on VE estimates was also explored. Nasopharyngeal swab samples were collected from outpatients with influenza-like illnesses (ILIs) in a community hospital in Nagasaki, Japan. Thirteen respiratory viruses (RVs), including influenza A and B, were identified from the samples using a multiplex polymerase chain reaction. The difference in VE point estimates was assessed using three different controls: ILI patients that tested negative for influenza, those that tested negative for all RVs, and those that tested positive for NIRVs. The adjusted VE against medically attended, laboratory-confirmed influenza using all influenza-negative controls was 5.3% (95% confidence interval [CI], -60.5 to 44.1). The adjusted VEs using RV-negative and NIRV-positive controls were -1.5% (95% CI, -74.7 to 41) and 50% (95% CI, -43.2 to 82.5), respectively. Influenza VE was limited in Japan during the 2011-2012 season. Although the evidence is not conclusive, co-circulating NIRVs may affect influenza VE estimates in test-negative case-control studies

Mechanisms Underlying Stage-1 TRPL Channel Translocation in Drosophila Photoreceptors

Background: TRP channels function as key mediators of sensory transduction and other cellular signaling pathways. In Drosophila, TRP and TRPL are the light-activated channels in photoreceptors. While TRP is statically localized in the signaling compartment of the cell (the rhabdomere), TRPL localization is regulated by light. TRPL channels translocate out of the rhabdomere in two distinct stages, returning to the rhabdomere with dark-incubation. Translocation of TRPL channels regulates their availability, and thereby the gain of the signal. Little, however, is known about the mechanisms underlying this trafficking of TRPL channels. Methodology/Principal Findings: We first examine the involvement of de novo protein synthesis in TRPL translocation. We feed flies cycloheximide, verify inhibition of protein synthesis, and test for TRPL translocation in photoreceptors. We find that protein synthesis is not involved in either stage of TRPL translocation out of the rhabdomere, but that re-localization to the rhabdomere from stage-1, but not stage-2, depends on protein synthesis. We also characterize an ex vivo eye preparation that is amenable to biochemical and genetic manipulation. We use this preparation to examine mechanisms of stage-1 TRPL translocation. We find that stage-1 translocation is: induced with ATP depletion, unaltered with perturbation of the actin cytoskeleton or inhibition of endocytosis, and slowed with increased membrane sterol content. Conclusions/Significance: Our results indicate that translocation of TRPL out of the rhabdomere is likely due to protei

Risk Factors of Streptococcus suis Infection in Vietnam. A Case-Control Study

Background: Streptococcus suis infection, an emerging zoonosis, is an increasing public health problem across South East Asia and the most common cause of acute bacterial meningitis in adults in Vietnam. Little is known of the risk factors underlying the disease. Methods and Findings: A case-control study with appropriate hospital and matched community controls for each patient was conducted between May 2006 and June 2009. Potential risk factors were assessed using a standardized questionnaire and investigation of throat and rectal S. suis carriage in cases, controls and their pigs, using real-time PCR and culture of swab samples. We recruited 101 cases of S. suis meningitis, 303 hospital controls and 300 community controls. By multivariate analysis, risk factors identified for S. suis infection as compared to either control group included eating "high risk" dishes, including such dishes as undercooked pig blood and pig intestine (OR1 = 2.22; 95% CI = [1.15-4.28] and OR2 = 4.44; 95% CI = [2.15-9.15]), occupations related to pigs (OR1 = 3.84; 95% CI = [1.32-11.11] and OR2 = 5.52; 95% CI = [1.49-20.39]), and exposures to pigs or pork in the presence of skin injuries (OR1 = 7.48; 95% CI = [1.97-28.44] and OR2 = 15.96; 95% CI = [2.97-85.72]). S. suis specific DNA was detected in rectal and throat swabs of 6 patients and was cultured from 2 rectal samples, but was not detected in such samples of 1522 healthy individuals or patients without S. suis infection. Conclusions: This case control study, the largest prospective epidemiological assessment of this disease, has identified the most important risk factors associated with S. suis bacterial meningitis to be eating 'high risk' dishes popular in parts of Asia, occupational exposure to pigs and pig products, and preparation of pork in the presence of skin lesions. These risk factors can be addressed in public health campaigns aimed at preventing S. suis infectio

Early Pandemic Influenza (2009 H1N1) in Ho Chi Minh City, Vietnam: A Clinical Virological and Epidemiological Analysis

Rogier van Doorn and colleagues analyze the initial outbreak, attempts at containment, and establishment of community transmission of pandemic H1N1 influenza in Ho Chi Minh City, Vietnam

A hidden HIV epidemic among women in Vietnam

<p>Abstract</p> <p>Background</p> <p>The HIV epidemic in Vietnam is still concentrated among high risk populations, including IDU and FSW. The response of the government has focused on the recognized high risk populations, mainly young male drug users. This concentration on one high risk population may leave other populations under-protected or unprepared for the risk and the consequences of HIV infection. In particular, attention to women's risks of exposure and needs for care may not receive sufficient attention as long as the perception persists that the epidemic is predominantly among young males. Without more knowledge of the epidemic among women, policy makers and planners cannot ensure that programs will also serve women's needs.</p> <p>Methods</p> <p>More than 300 documents appearing in the period 1990 to 2005 were gathered and reviewed to build an understanding of HIV infection and related risk behaviors among women and of the changes over time that may suggest needed policy changes.</p> <p>Results</p> <p>It appears that the risk of HIV transmission among women in Vietnam has been underestimated; the reported data may represent as little as 16% of the real number. Although modeling predicted that there would be 98,500 cases of HIV-infected women in 2005, only 15,633 were accounted for in reports from the health system. That could mean that in 2005, up to 83,000 women infected with HIV have not been detected by the health care system, for a number of possible reasons. For both detection and prevention, these women can be divided into sub-groups with different risk characteristics. They can be infected by sharing needles and syringes with IDU partners, or by having unsafe sex with clients, husbands or lovers. However, most new infections among women can be traced to sexual relations with young male injecting drug users engaged in extramarital sex. Each of these groups may need different interventions to increase the detection rate and thus ensure that the women receive the care they need.</p> <p>Conclusion</p> <p>Women in Vietnam are increasingly at risk of HIV transmission but that risk is under-reported and under-recognized. The reasons are that women are not getting tested, are not aware of risks, do not protect themselves and are not being protected by men. Based on this information, policy-makers and planners can develop better prevention and care programs that not only address women's needs but also reduce further spread of the infection among the general population.</p

Science journalism for development in the Global South: A systematic literature review of issues and challenges

Based primarily on a systematic review of the relevant literature between 2000 and 2017, this paper reflects on the state of journalism about science in developing countries, with a focus on its issues, challenges and implications for their developmental processes and causes. Five major themes emerge from our analysis: (a) heavy dependence on foreign sources, especially the media of the Global North; (b) the low status of domestic science news in newsrooms; (c) uncritical science reporting that lends itself to easy influences of non-science vested interests; (d) tight grips of politics on science journalism; and (e) ineffective relationships between science and journalism. We will demonstrate that, while some of these problems exist in the North, they can have far more severe consequences on the progress of the South, where news plays an almost exclusive role in informing and engaging laypeople with science and its socio-cultural, economic and political implications

Regional research priorities in brain and nervous system disorders

The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities.Fil: Ravindranath, Vijayalakshmi. Indian Institute of Science; IndiaFil: Dang, Hoang Minh. Vietnam National University; VietnamFil: Goya, Rodolfo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata ; ArgentinaFil: Mansour, Hader. University of Pittsburgh; Estados Unidos. Mansoura University; EgiptoFil: Nimgaonkar, Vishwajit L.. University of Pittsburgh; Estados UnidosFil: Russell, Vivienne Ann. University of Cape Town; SudáfricaFil: Xin, Yu. Peking University; Chin