Giant magnetic field from moir\'e induced Berry phase in homobilayer semiconductors

When quasiparticles move in condensed matters, the texture of their internal quantum structure as a function of position and momentum can give rise to Berry phases that have profound effects on materials properties. Seminal examples include the anomalous Hall and spin Hall effects from the momentum-space Berry phases in homogeneous crystals. Here we explore a conjugate form of electron Berry phase arising from the moir\'e pattern, the texture of atomic configurations in real space. In homobilayer transition metal dichalcogenides, we show the real-space Berry phase from moir\'e manifests as a periodic magnetic field up to hundreds of Tesla. This quantity tells apart moir\'e patterns from different origins, which can have identical potential landscape but opposite quantized magnetic flux per supercell. For low energy carriers, the homobilayer moir\'es realize topological flux lattices for the quantum spin Hall effect. An interlayer bias can continuously tune the spatial profile of moir\'e magnetic field, whereas the flux per supercell is a topological quantity that can only have a quantized jump observable at moderate bias. We also reveal the important role of the non-Abelian Berry phase in shaping the energy landscape in small moir\'e. Our work points to new possibilities to access ultra-high magnetic field that can be tailored in the nanoscale by electrical and mechanical controls

Some Phenomenologies of Unparticle Physics

Fermionic unparticles are introduced and their basic properties are discussed. Some phenomenologies related are exploited, such as their effects on charged Higgs boson decays and anomalous magnetic moments of leptons. Also, it has been found that measurements of $B^0-\bar B^0$ mixing could yield interesting constraints on couplings between unparticle operators and standard model fields.Comment: Version to appear in Phys. Letts. B. 9 pages, 3 figure

A novel circularly polarized filtering antenna with high out‐of‐band radiation rejection level

In this paper, a circularly polarized filtering antenna with high out‐of‐band radiation rejection level is proposed. The entire design consists of a patch and a filtering feeding network, which are connected by metallic pins. First, a high‐selectivity filtering power divider is constructed utilizing two shunted bandpass filter. Next, a 90° phase difference could be realized by adjusting the length of the two outputs of the power divider. The measured transmission coefficient of the feeding network is 6.3 dB at 2 GHz. The measured axial ratio is below 3 dB within the operating band of the proposed antenna, which represents the effectiveness of the proposed feeding network. In addition, the obvious radiation nulls can be found from the antenna measurement because of the transmission zeros introducing by the filtering power divider. The measured gain is 5.73 dB at 2 GHz and decreases dramatically in stopband. Specially, the measured gain is −30 and −41 dB at 1.95 and 2.06 GHz. The proposed antenna has an excellent filtering characteristic compared with those without the filtering feeding network. To sum up, the proposed antenna and filtering power divider are promising in the modern wireless communication systems.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140028/1/mop30929.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/140028/2/mop30929_am.pd

Assessment of the spatial and temporal variations of water quality for agricultural lands with crop rotation in China by using a HYPE model

Many water quality models have been successfully used worldwide to predict nutrient losses from anthropogenically impacted catchments, but hydrological and nutrient simulations with little data are difficult considering the transfer of model parameters and complication of model calibration and validation. This study aims (i) to assess the performance capabilities of a new and relatively more advantageous model-hydrological predictions for the environment (HYPE) to simulate stream flow and nutrient load in ungauged agricultural areas by using a multi-site and multi-objective parameter calibration method and (ii) to investigate the temporal and spatial variations of total nitrogen (TN) and total phosphorous (TP) concentrations and loads with crop rotation using the model for the first time. A parameter estimation tool (PEST) was used to calibrate parameters, which shows that the parameters related to the effective soil porosity were most sensitive to hydrological modeling. N balance was largely controlled by soil denitrification processes, whereas P balance was influenced by the sedimentation rate and production/decay of P in rivers and lakes. The model reproduced the temporal and spatial variations of discharge and TN/TP relatively well in both calibration (2006–2008) and validation (2009–2010) periods. The lowest NSEs (Nash-Suttclife Efficiency) of discharge, daily TN load, and daily TP load were 0.74, 0.51, and 0.54, respectively. The seasonal variations of daily TN concentrations in the entire simulation period were insufficient, indicated that crop rotation changed the timing and amount of N output. Monthly TN and TP simulation yields revealed that nutrient outputs were abundant in summer in terms of the corresponding discharge. The area-weighted TN and TP load annual yields in five years showed that nutrient loads were extremely high along Hong and Ru rivers, especially in agricultural lands

OR-027 Research about Training Monitoring during Different training periods in Chinese Elite Swimmers

Objective Training monitoring has become an integral component of total athlete training. Systematically monitoring the physiological and biochemical variables related to performance helps coaches and athletes to measure the effectiveness of their training programs and decide how to revise or update those programs, especially in swimming training. The key purpose of this study is to evaluate the physical function characteristics during preparation season and stress response during competition training sessions in 2017, and provides the helpful data for scientific training for the implementation of the preparation process. Methods During the preparation period, the National Swimming Team athletes were planed to screen and test the physical function characteristics. There are 39 male athletes and 37 female athletes to participate in the study. Body composition was assessed with dual energy X-ray (DXA). Anthropometric characteristics were assessed using Anthroscan 3D VITUS body scanner, and pulmonary function test using CHEST portable lung function meter(HI-101). During the competition period, the training load monitoring targets were 2 elite players who participated in XVII World Aquatics Championship in Budapest-2017 and the National Games 2017. The monitoring methods mainly included: blood tests (including Hb, CK, BU, testosterone, cortisol and ferritin etc.) were used to monitor the athlete's fitness functional status, and the Z-score method was used to express the index changes of two athletes; blood lactate was used to monitor the training load of athletes, and urine indexes were used to monitor body fluid balance and fatigue. Results 1. During the preparation period, the weight of male athletes is 78.4±8.2kg, the percentage of body fat is 15.9±2.8%, the weight of female athletes is 64.8±6.6kg, and the percentage of body fat is 24.2±3.5%. The vital capacity(VC) was 6.65±0.87 L for males and 4.86±0.69 L for females, the value of forced vital capacity(FVC) was 4.29±1.33 L for males and 3.43±0.96 L for females, and the mean value of ventilation per minute was 148.1±23.12 L for males and 110.4 ± 19.67 L for females. 2. During the competition preparation period, Z score was used to express the blood indicators of two athletes, before the XVII World Aquatics Championship in Budapest-2017, the Z score of Hb, T, T/C ratio and ferritin were (-0.5, 0, -0.4, 1.1) and (-0.8, -0.1, -1.0, 0), respectively. Before the competition of the National Games, the Z scores were (1.0, 0.3, 0.7, 0.6) and (1.4, 1.0, 0.1, -0.6) respectively. 3. Training load monitoring was carried out using the blood lactate control test, as the training load increased, the athletes' performance improved and the lactate level increased slightly. 4. The urine indicator test is used to observe the athlete's dehydration and recovery. On the second morning after the intensive training day, both athletes were negative for urine protein and with normal urine specific gravity. Conclusions 1. The screen and tests about the physical function characteristics of swimming athletes during preparation period is useful to develop a personalized training plan; 2. Z-score is easy and feasible for the elite swimmers to monitoring physical fitness capabilities, and higher Z-score is related with better athletic performance; 3. Blood lactate control test can be used for the training intensity monitoring of swimmers, athletes show higher levels of lactic acid metabolism and higher athletic performance before the competition

Co-infusion of haplo-identical CD19-chimeric antigen receptor T cells and stem cells achieved full donor engraftment in refractory acute lymphoblastic leukemia

Abstract Background Elderly patients with relapsed and refractory acute lymphoblastic leukemia (ALL) have poor prognosis. Autologous CD19 chimeric antigen receptor-modified T (CAR-T) cells have potentials to cure patients with B cell ALL; however, safety and efficacy of allogeneic CD19 CAR-T cells are still undetermined. Case presentation We treated a 71-year-old female with relapsed and refractory ALL who received co-infusion of haplo-identical donor-derived CD19-directed CAR-T cells and mobilized peripheral blood stem cells (PBSC) following induction chemotherapy. Undetectable minimal residual disease by flow cytometry was achieved, and full donor cell engraftment was established. The transient release of cytokines and mild fever were detected. Significantly elevated serum lactate dehydrogenase, alanine transaminase, bilirubin and glutamic-oxalacetic transaminase were observed from days 14 to 18, all of which were reversible after immunosuppressive therapy. Conclusions Our preliminary results suggest that co-infusion of haplo-identical donor-derived CAR-T cells and mobilized PBSCs may induce full donor engraftment in relapsed and refractory ALL including elderly patients, but complications related to donor cell infusions should still be cautioned. Trial registration Allogeneic CART-19 for Elderly Relapsed/Refractory CD19+ ALL. NCT0279955

A lytic phage to control multidrug-resistant avian pathogenic Escherichia coli (APEC) infection

The inappropriate use of antibiotics has led to the emergence of multidrug-resistant strains. Bacteriophages (phages) have gained renewed attention as promising alternatives or supplements to antibiotics. In this study, a lytic avian pathogenic Escherichia coli (APEC) phage designated as PEC9 was isolated and purified from chicken farm feces samples. The morphology, genomic information, optimal multiplicity of infection (MOI), one-step growth curve, thermal stability, pH stability, in vitro antibacterial ability and biofilm formation inhibition ability of the phage were determined. Subsequently, the therapeutic effects of the phages were investigated in the mice model. The results showed that PEC9 was a member of the siphovirus-like by electron microscopy observation. Biological characterization revealed that it could lyse two serotypes of E. coli, including O1 (9/20) and O2 (6/20). The optimal multiplicity of infection (MOI) of phage PEC9 was 0.1. Phage PEC9 had a latent period of 20 min and a burst period of 40 min, with an average burst size of 68 plaque-forming units (PFUs)/cell. It maintained good lytic activity at pH 3-11 and 4-50°C and could efficiently inhibit the bacterial planktonic cell growth and biofilm formation, and reduce bacterial counts within the biofilm, when the MOI was 0.01, 0.1, and 1, respectively. Whole-genome sequencing showed that PEC9 was a dsDNA virus with a genome of 44379 bp and GC content of 54.39%. The genome contains 56 putative ORFs and no toxin, virulence, or resistance-related genes were detected. Phylogenetic tree analysis showed that PEC9 is closely related to E. coli phages vB_EcoS_Zar3M, vB_EcoS_PTXU06, SECphi18, ZCEC10, and ZCEC11, but most of these phages exhibit different gene arrangement. The phage PEC9 could successfully protect mice against APEC infection, including improved survival rate, reduced bacterial loads, and organ lesions. To conclude, our results suggest that phage PEC9 may be a promising candidate that can be used as an alternative to antibiotics in the control of APEC infection