2 research outputs found
Fluctuations in Serum magnesium and Systemic Arterial Blood Pressures during the Menstrual Cycle in young reproductive women
Introduction: The menstrual cycle involves a sequence of structural, functional, and hormonal changes in the
reproductive system. This is linked and controlled by cyclical fluctuations in the levels of FSH, LH, estrogen,
and progesterone. Because of these cyclical fluctuations, there might also be associated cyclical changes of
magnesium and systemic arterial blood pressures during the menstrual cycle. Purpose: To assess the changes in
serum magnesium level and systemic arterial blood pressures during the menstrual cycle in young reproductive
women. Methodology: the sample population is 40 apparently healthy young reproductive-aged 18- 25years
female students from the University of Medicine, Magway participated in this study. Systemic arterial blood
pressures were measured by indirect method. The serum magnesium level was measured by spectrophotometry.
These measurements were done in the early follicular phase (EF), the peri-ovulatory phase (PO), and the midluteal phase (ML) of the menstrual cycle. The serum magnesium levels were significantly (p <0.001) lower, and
the systolic blood pressures were significantly higher (p <0.05) in the PO than the EF and the ML. In the EF,
there was a significant negative correlation between serum magnesium level and diastolic blood pressure (r= -
0.374, p <0.05) and mean arterial pressure (r = -0.354, p < 0.05) but no significant correlation with systolic blood
pressure. In the PO, there was no significant correlation between serum magnesium level and systemic arterial
blood pressures. In the ML, there was significant negative correlation between serum magnesium level and
systolic blood pressure (r = -0.651, p <0.001), diastolic blood pressure (r = -0.607, p <0.001), and mean arterial
pressure (r = -0.661, p <0.001). Conclusion: The study concludes that serum magnesium level has a negative
effect on blood pressure changes and the blood pressure-lowering effect of magnesium. These changes are
related to the fluctuation of estrogen levels during the menstrual cycle.
KEYWORDS: Serum magnesium, systemic arterial blood pressures, menstrual cycle reproductive syste