55 research outputs found

    Closed embeddings into Lipscomb\u27s universal space

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    Let J(τ) be Lipscomb\u27s one-dimensional space and Ln(τ) = {x J(τ)n+1 | at least one coordinate of x is irrational} J(τ)n+1 Lipscomb\u27s n-dimensional universal space of weight τ ≥ אo. In this paper we prove that if X is a complete metrizable space and dim X ≤ n, w X ≤ τ, then there is a closed embedding of X into Ln(τ). Furthermore, any map f : X → J(τ)n+1 can be approximated arbitrarily close by a closed embedding ψ : X → Ln(τ). Also, relative and pointed versions are obtained. In the separable case an analogous result is obtained, in which the classic triangular Sierpinski curve (homeomorphic to J(3)) is used instead of J(אo)

    Chapter One – An Overview of Architecture-Level Power- and Energy-Efficient Design Techniques

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    Power dissipation and energy consumption became the primary design constraint for almost all computer systems in the last 15 years. Both computer architects and circuit designers intent to reduce power and energy (without a performance degradation) at all design levels, as it is currently the main obstacle to continue with further scaling according to Moore's law. The aim of this survey is to provide a comprehensive overview of power- and energy-efficient “state-of-the-art” techniques. We classify techniques by component where they apply to, which is the most natural way from a designer point of view. We further divide the techniques by the component of power/energy they optimize (static or dynamic), covering in that way complete low-power design flow at the architectural level. At the end, we conclude that only a holistic approach that assumes optimizations at all design levels can lead to significant savings.Peer ReviewedPostprint (published version

    Promene intenziteta erozije na teritoriji opštine Zaječar

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    Apart from other geomorphologic processes (glacial erosion, nivation, abrasion) which are predominantly determined by the intensity of natural factors, soil erosion is significantly determined by anthropogenic influences. Despite the fact that the physical-geographic factors are important determinants of the erosion intensity this geomorphologic process has also demographic, socio-economic, environmental, and multidisciplinary aspects as well. Control works, some demographic characteristics of the territory and the type of land use are the direct and indirect anthropogenic influences and modifiers of the intensity of this process. The basic idea of this paper is to assess the basic socio-geographic change over certain area and to determine its effects on the erosion intensity.Za razliku od drugih geomorfoloških procesa (glacijalne erozije, nivacije, abrazije) čiji je intenzitet dominantno determinisan prirodnim faktorima, erozija zemljišta je značajno određena i antropogenim uticajima. I pored činjenice da su fizičko-geografske karakteristike prostora važne determinante intenziteta erozije zemljišta, ovaj geomorfološki proces ima demografski, socio-ekonomski, ekološki, ali i multidisciplinarni aspekt. Antierozivni radovi, demografske karakteristike neke teritorije i namena korišćenja zemljišta predstavljaju direktne i indirektne antropogene uticaje, odnosno modifikatore intenziteta ovog procesa. Osnovna ideja ovog rada je sagledavanje osnovnih društveno-geografskih promena na nekoj teritoriji i utvrđivanje njihovog uticaja na promenu intenziteta erozije zemljišta

    Adsorption of nicotine from aqueous solutions on montmorillonite and acid – modified montmorillonite

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    Montmorillonite (Mt) and acid modified montmorillonite (MtA) were tested as nicotine adsorbents. The samples were characterized using FT-IR spectroscopy and low temperature nitrogen physisorption. Nicotine adsorption was performed with respect to contact time, pH and initial nicotine concentration. The kinetics of adsorption obeyed the pseudo-second-order kinetics. The optimal pH values for nicotine adsorption were 6 and 9 for Mt and MtA, respectively. The isotherms related to adsorption on Mt at pH = 6 and 9 as well as for MtA at pH=6 were best fitted with Sips isotherm model, while adsorption onto MtA at pH=9 obeyed Langmuir isotherm model.Монморијонит (Mt) и кисело модификован монморијонит (MtA) су испитани као адсорбенси никотина. Узорци су окарактерисани FT-IR спектроскопијом и нискотемпературном физисорпцијом азота. Адсорпција никотина испитивана је у зависности од времена контакта, pH и почетне концентрације никотина. Псеудодруги ред добро описује кинетику адсорпције. Оптимална pH вредност за адсорпцију никотина на Mt је 6 док је за MtA 9. Сипсов модел најбоље описује адсорпцију никотина на Mt на pH = 6 и 9 као и на MtA на pH = 6, док се aдсорпција на MtA на pH = 9 одвија по Лангмировом моделу

    Impact of bee venom and melittin on apoptosis and biotransformation in colorectal carcinoma cell lines

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    © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. This study provides data about anticancer properties of bee venom and its dominant compound, melittin on colorectal carcinoma cells (HCT-116 and SW-480) in regard to their proapoptotic activity and expression of genes involved in biotransformation process. Based on results, they are strong cytotoxins, where the melittin showed also selectivity against cancer cells compared to normal, HaCat. They induce proapoptotic activity by affecting apoptosis signaling molecules (Fas receptors, caspase 9, and members of Bcl-2 family of proteins) and mainly suppress expression of genes involved in their biotransformation, suggesting their ability to develop the resistance of colorectal cancer cells

    Integrated luminosity measurement at CEPC

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    The very forward region is one of the most challenging regions to instrument at a future e+ee^+e^- collider. At CEPC, machine-detector interface includes, among others, a calorimeter dedicated for precision measurement of the integrated luminosity at a permille level or better. Here we review a feasibility of such precision, from the point of view of luminometer mechanical precision and positioning, beam-related requirements and physics background.A method of the effective center-of-mass determination from e+eμ+μe^+e^- \to \mu^+\mu^-, initially proposed for FCC, is also discussed for the CEPC beams.Comment: Talk presented at the International Workshop on Future Linear Colliders (LCWS2021), 15-18 March 2021. C21-03-15.1. arXiv admin note: text overlap with arXiv:2010.15061, arXiv:2002.0366

    Measurement of the Higgs Branching Ration BR(HγγH\rightarrow\gamma\gamma) at 3 TeV CLIC

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    In this paper we address the potential of a 3 TeV center-of-mass energy Compact Linear Collider (CLIC) to measure the Standard Model (SM) Higgs boson decay to two photons. Since photons are massless, they are not coupled to the Higgs boson at the tree level, but they are created in a loop exchange of heavy particles either from the Standard Model or beyond. Any deviation of the effective HγγH\rightarrow\gamma\gamma branching ratio and consequently of the Higgs to photon coupling may indicate New Physics. The Higgs decay to two photons is thus an interesting probe of the Higgs sector, both at the running and future experiments. A similar study has been performed by C. Grefe at 1.4 TeV CLIC, where the statistical uncertainty is determined to be 15\% for an integrated luminosity of 1.5 ab1ab^{-1} with unpolarized beams. \noindent This study is performed using a full simulation of the detector for CLIC and by considering all relevant physics and beam-induced processes in a full reconstruction chain. The measurement is simulated on 5000 samples of pseudo-experiments and the relative statistical uncertainty is extracted from the pull distribution. It is shown that the Higgs production cross-section in W+WW^+W^- fusion times the branching ratio BR(HγγH\rightarrow\gamma\gamma) can be measured with a relative statistical accuracy of 8.2\%, assuming an integrated luminosity of 5 ab1ab^{-1} with unpolarized beams

    CP violation in the Higgs sector at ILC

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    CP violation is one of Sakharov's condition for the matter-antimatter asymmetry of the Universe. The experimentally observed size of CP violation is insufficient to account for this. Is CP violated in the Higgs sector? Could the SM-like Higgs boson be a mixture of CP even and CP odd states of an extended Higgs sector? With what precision could such effects be measured at future electron-positron colliders? These questions will be discussed in the light of the latest studies at ILC

    Povezanost tipa preloma kosti i stepena formiranja kalusa sa koncentracijom leptina kod dece sa prelomima dugih kostiju

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    Background/Aim. Recent studies indicate that adipokines have an important role in bone physiology and pathology. Recent data indicate that adipokine leptin functions as a regulator of bone growth at multiple levels, systemically and locally. So far, it has been shown that leptin influences bone volume and bone mineral density in a population with metabolic and/or hormonal abnormality. Data concerning leptin values in non-obese children with fractures are scarce. Methods. This study included 93 non-obese children with long bone fractures (LBF), 14 children with short bone fractures (SBF), and 19 healthy children. Leptin concentration was determined in two blood samples (day 0 and day 21) and analyzed according to gender, fracture type, anatomical localization of the fracture, fracture topography, callus formation, and the healing outcome. Results. Children with LBF demonstrated significantly increased leptin levels compared to the control group (both day 0/day 21). In the control group, girls had significantly more leptin than boys. Leptin value was significantly influenced by anatomical localization since boys and girls with humerus fracture and girls with femur fracture had the highest average leptin concentration in the initial sample. Boys with incomplete callus formation had the highest leptin concentration (both day 0/day 21), significantly elevated compared to boys' samples in the control group, boys' samples with an intermediary and well-formed callus, and also increased compared to the initial samples of girls with incomplete callus. Better callus formation in girls was associated with an increment of leptin concentrations in the second over the initial sample. Girls with partially and satisfactorily formed callus had significantly increased leptin concentration in the second sample (day 21) compared to the boys' group. Conclusion. Leptin concentration was significantly increased (both samples) in children with LBF compared to children with SBF and corresponding controls. Leptin concentration was highly influenced by gender. High blood leptin concentrations in boys or low leptin concentrations in girls immediately upon fracture could be used to identify groups of children with incomplete callus formation.Uvod/Cilj.Novijestudije pokazuju da adipokini imaju važnu ulogu u fiziologiji i patologiji kostiju. Takođe, najnoviji podaci pokazuju da adipokin leptin funkcioniše kao regulator rasta kostiju sistemski i lokalno. Pokazano je da leptin utiče na volumen kostiju i mineralnu gustinu kostiju u populaciji sa metaboličkom i/ili hormonskom abnormalnošću. Podaci o vrednostima leptina kod negojazne dece sa frakturama su oskudni. Metode. U ovu studijubil a su uključena93 negojazna deteta sa prelomima dugih kostiju (LBF), 14 dece sa prelomima malih kostiju (SBF) i 19 zdrave dece. Koncentracija leptina određena je u 2 uzorka krvi (0. danai 21 . dana) i analizirana prema polu, tipu frakture, lokalizaciji anatomske frakture, topografiji frakture, formiranju kalusa i ishodu zarastanja.Rezultati.Deca sa LBF imala su značajnopovećane nivoeleptina u poređenju sa kontrolnom grupom u oba uzorka krvi ( 0. dana/21 . dana). U kontrolnoj grupi devojčice su imale značajno više nivoe leptina od dečaka. Na vrednost leptina značajno je uticala anatomska lokalizacija, jer su dečaci i devojčice sa prelomom humerusa i devojčice sa prelomom femura imali najveću prosečnu koncentraciju leptina u početnom uzorku. Dečaci sa nepotpuno for miranim kalusom imali su najveću koncentraciju leptina (u oba uzorka, 0. dana/21. dana),značajno višuu odnosu na kontrolne uzorke dečaka, uzorke dečaka s intermedijarnim i dobro formiranim kalusom, a takođe višu u odnosu na koncentracije leptina u početnim uzorcima djevojčica s nepotpunim kalusom. Bolje formiranje kalusa kod devojčica je bilo povezano sa poveć anjem koncentracije leptina u drugom (21. dan) u odnosu na početni uzorak(0. dan). Devojčice sa delimično i zadovoljavajuće formiranim kalusom imale su značajno višu koncentraciju leptina u drugom uzorku (21. dan ) u odnosu na grupu dečaka. Zaključak. Koncentracija leptina je značajno povećana (u oba uzorkakrvi ) kod dece sa LBF u poređenju sa decom sa SBF i odgovarajućim kontrolama. Koncentracija leptina je zavisna od pola. Visok nivo leptina u krvi kod dečaka ili niska koncentracija leptina kod devojčica odmah nakon preloma može se koristiti za identifikaciju grupa dece sa nepotpunim formiranjem kalusa
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