2,978 research outputs found
Activating Library Classrooms: Evaluating Formal Learning Spaces for Active Learning and Student Engagement
Funded by the Association of College & Research Libraries through a 2018 Academic Library Impact Research Grant, the Activating Library Classrooms: Evaluating Formal Learning Spaces for Active Learning and Student Engagement project endeavored to evaluate the design and use of formal learning spaces situated within X X University Libraries. Researchers evaluated seven library classrooms and interviewed seven faculty collaborators at six X X University campuses in order to identify areas of strength and growth for formal learning spaces. The results affirm the significance of formal learning spaces in libraries and how they can demonstrate academic libraries’ ability to partner in university curricula and student success
Classifications of Computable Structures
Let K be a family of structures, closed under isomorphism, in a fixed computable language. We consider effective lists of structures from K such that every structure in K is isomorphic to exactly one structure on the list. Such a list is called a computable classification of K, up to isomorphism. Using the technique of Friedberg enumeration, we show that there is a computable classification of the family of computable algebraic fields, and that with a 0\u27-oracle, we can obtain similar classifications of the families of computable equivalence structures and of computable finite-branching trees. However, there is no computable classification of the latter, nor of the family of computable torsion-free abelian groups of rank 1, even though these families are both closely allied with computable algebraic fields
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Comparison of family centered care with family integrated care and mobile technology (mFICare) on preterm infant and family outcomes: a multi-site quasi-experimental clinical trial protocol.
BackgroundFamily Centered Care (FCC) has been widely adopted as the framework for caring for infants in the Neonatal Intensive Care Unit (NICU) but it is not uniformly defined or practiced, making it difficult to determine impact. Previous studies have shown that implementing the Family Integrated Care (FICare) intervention program for preterm infants in the NICU setting leads to significant improvements in infant and family outcomes. Further research is warranted to determine feasibility, acceptability and differential impact of FICare in the US context. The addition of a mobile application (app) may be effective in providing supplemental support for parent participation in the FICare program and provide detailed data on program component uptake and outcomes.MethodsThis exploratory multi-site quasi-experimental study will compare usual FCC with mobile enhanced FICare (mFICare) on growth and clinical outcomes of preterm infants born at or before 33 weeks gestational age, as well as the stress, competence and self-efficacy of their parents. The feasibility and acceptability of using mobile technology to gather data about parent involvement in the care of preterm infants receiving FCC or mFICare as well as of the mFICare intervention will be evaluated (Aim 1). The effect sizes for infant growth (primary outcome) and for secondary infant and parent outcomes at NICU discharge and three months after discharge will be estimated (Aim 2).DiscussionThis study will provide new data about the implementation of FICare in the US context within various hospital settings and identify important barriers, facilitators and key processes that may contribute to the effectiveness of FICare. It will also offer insights to clinicians on the feasibility of a new mobile application to support parent-focused research and promote integration of parents into the NICU care team in US hospital settings.Trial registrationClinicalTrials.gov, ID NCT03418870. Retrospectively registered on December 18, 2017
Lived Experiences of Human Subjects Researchers and Vicarious Trauma
The purpose of this consensual qualitative research (CQR) study was to describe the essence of the experiences of 10 human subject researchers who have been impacted by research-related trauma. After the data was collected, transcribed, and coded, five main themes emerged from this study: (1) data engagement; (2) symptoms and impacts; (3) coping; (4) weight of representation; and (5) support. Findings of this study may help research supervisors and higher education leaders have greater awareness of how vicarious trauma may impact students and professionals who engage in research regarding traumatic content. The findings in this article can be used to recognize trauma in researchers, as well as springboard further discussions of vicarious trauma. Researcher supervisors and higher education leaders can reflect on their role in recognizing and mitigating vicarious trauma. Recommendations for future research include expanding identities for researchers using the CQR method and participants recruited, finding effective strategies and policies, exploring the incidental theme of dehumanization, and conducting quantitative studies
The psychology of AMBER Alert: Unresolved issues and implications
The AMBER alert system is likely affected by a number of psychological processes, yet remains understudied. The system assumes people will remember Alert information accurately and notify police, but psychological research on related phenomena (e.g., memory, willingness to help) indicates that people may not be able or willing to act in ways the promote the success of the system. In addition, the system is intended to deter child abductions, however, the system could prompt copycat crimes from perpetrators seeking publicity. The system could also cause a precipitation effect in which a perpetrator who sees the Alert could decide to murder the child immediately to avoid capture. Policy recommendations are made based on psychological research and theory, although more research is needed to develop the most effective system possible
Neural Correlates of Suspiciousness and Interactions with Anxiety During Emotional and Neutral Word Processing
Suspiciousness is usually classified as a symptom of psychosis, but it also occurs in depression and anxiety disorders. Though how suspiciousness overlaps with depression is not obvious, suspiciousness does seem to overlap with anxious apprehension and anxious arousal (e.g., verbal iterative processes and vigilance about environmental threat). However, suspiciousness also has unique characteristics (e.g., concern about harm from others and vigilance about social threat). Given that both anxiety and suspiciousness have been associated with abnormalities in emotion processing, it is unclear whether it is the unique characteristics of suspiciousness or the overlap with anxiety that drive abnormalities in emotion processing. Event-related brain potentials were obtained during an emotion-word Stroop task. Results indicated that suspiciousness interacts with anxious apprehension to modulate initial stimulus perception processes. Suspiciousness is associated with attention to all stimuli regardless of emotion content. In contrast, anxious arousal is associated with a later response to emotion stimuli only. These results suggest that suspiciousness and anxious apprehension share overlapping processes, but suspiciousness alone is associated with a hyperactive early vigilance response. Depression did not interact with suspiciousness to predict response to emotion stimuli. These findings suggest that it may be informative to assess suspiciousness in conjunction with anxiety in order to better understand how these symptoms interact and contribute to dysfunctional emotion processing
Chronic Disease Self-Management: A Hybrid Concept Analysis
BACKGROUND:
Chronic diseases require chronic disease self-management (CDSM). Existing CDSM interventions, while improving outcomes, often do not lead to long-lasting effects. To render existing and new CDSM interventions more effective, an exploration of the concept of CDSM from both the literature and patient perspectives is needed. The purpose of this study was to describe the current conceptualization of CDSM in the literature, identify potential inadequacies in this conceptualization based on a comparison of literature- and patient-based CDSM descriptions, and to offer a more comprehensive definition of CDSM.
METHODS:
A hybrid concept analysis was completed.
DISCUSSION:
In the literature, CDSM is defined as behaviors influenced by individual characteristics. Patients in the fieldwork phase discussed aspects of CDSM not well represented in the literature.
CONCLUSIONS:
CDSM is a complex process involving behaviors at multiple levels of a person's environment. Pilot work to develop and test CDSM interventions based on both individual and external characteristics is needed
An Sp185/333 gene cluster from the purple sea urchin and putative microsatellite-mediated gene diversification
Abstract
Background
The immune system of the purple sea urchin, Strongylocentrotus purpuratus, is complex and sophisticated. An important component of sea urchin immunity is the Sp185/333 gene family, which is significantly upregulated in immunologically challenged animals. The Sp185/333 genes are less than 2 kb with two exons and are members of a large diverse family composed of greater than 40 genes. The S. purpuratus genome assembly, however, contains only six Sp185/333 genes. This underrepresentation could be due to the difficulties that large gene families present in shotgun assembly, where multiple similar genes can be collapsed into a single consensus gene.
Results
To understand the genomic organization of the Sp185/333 gene family, a BAC insert containing Sp185/333 genes was assembled, with careful attention to avoiding artifacts resulting from collapse or artificial duplication/expansion of very similar genes. Twelve candidate BAC assemblies were generated with varying parameters and the optimal assembly was identified by PCR, restriction digests, and subclone sequencing. The validated assembly contained six Sp185/333 genes that were clustered in a 34 kb region at one end of the BAC with five of the six genes tightly clustered within 20 kb. The Sp185/333 genes in this cluster were no more similar to each other than to previously sequenced Sp185/333 genes isolated from three different animals. This was unexpected given their proximity and putative effects of gene homogenization in closely linked, similar genes. All six genes displayed significant similarity including both 5' and 3' flanking regions, which were bounded by microsatellites. Three of the Sp185/333 genes and their flanking regions were tandemly duplicated such that each repeated segment consisted of a gene plus 0.7 kb 5' and 2.4 kb 3' of the gene (4.5 kb total). Both edges of the segmental duplications were bounded by different microsatellites.
Conclusions
The high sequence similarity of the Sp185/333 genes and flanking regions, suggests that the microsatellites may promote genomic instability and are involved with gene duplication and/or gene conversion and the extraordinary sequence diversity of this family
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