7,011 research outputs found
A Mandated Minimum Competency Testing Program and Its Impact on Learning Disabled Students: Curricular Validity and Comparative Performances
This research was published by the KU Center for Research on Learning, formerly known as the University of Kansas Institute for Research in Learning Disabilities.In this study, LD specialists, regular class teachers, and parents of LD students judged that the objectives of the Kansas Minimum Competency Specifications prescribed for nonhandicapped students were applicable to LD students. In addition, the Kansas Minimal Competency Test was administered to LD students under standard and oral conditions. Results showed that they did not perform as well as their nonhandicapped peers at any of the five grade levels. The test was then administered under two modified conditions. Learning disabled students' performance on some objectives at every grade level was not improved by either administering items orally or administering the test one grade level above that designated for nonhandicapped students
Flight controller alertness and performance during MOD shiftwork operations
Decreased alertness and performance associated with fatigue, sleep loss, and circadian disruption are issues faced by a diverse range of shiftwork operations. During STS operations, MOD personnel provide 24 hr. coverage of critical tasks. A joint JSC and ARC project was undertaken to examine these issues in flight controllers during MOD shiftwork operations. An initial operational test of procedures and measures was conducted during STS-53 in Dec. 1992. The study measures included a background questionnaire, a subjective daily logbook completed on a 24 hr. basis (to report sleep patterns, work periods, etc.), and an 8 minute performance and mood test battery administered at the beginning, middle, and end of each shift period. Seventeen Flight controllers representing the 3 Orbit shifts participated. The initial results clearly support further data collection during other STS missions to document baseline levels of alertness and performance during MOD shiftwork operations. These issues are especially pertinent for the night shift operations and the acute phase advance required for the transition of day shift personnel into the night for shuttle launch. Implementation and evaluation of the countermeasure strategies to maximize alertness and performance is planned. As STS missions extend to further extended duration orbiters, timelines and planning for 24 circadian disruption will remain highly relevant in the MOD environment
A rare presentation of atypical demyelination: tumefactive multiple sclerosis causing Gerstmann's syndrome
r. KS has been supported by a Higher Education Funding Council for
England (HEFCE) Clinical Senior Lectureshi
A modular synthetic device to calibrate promoters
In this contribution, a design of a synthetic calibration genetic circuit to
characterize the relative strength of different sensing promoters is proposed
and its specifications and performance are analyzed via an effective
mathematical model. Our calibrator device possesses certain novel and useful
features like modularity (and thus the possibility of being used in many
different biological contexts), simplicity, being based on a single cell, high
sensitivity and fast response. To uncover the critical model parameters and the
corresponding parameter domain at which the calibrator performance will be
optimal, a sensitivity analysis of the model parameters was carried out over a
given range of sensing protein concentrations (acting as input). Our analysis
suggests that the half saturation constants for repression, sensing and
difference in binding cooperativity (Hill coefficients) for repression are the
key to the performance of the proposed device. They furthermore are determinant
for the sensing speed of the device, showing that it is possible to produce
detectable differences in the repression protein concentrations and in turn in
the corresponding fluorescence in less than two hours. This analysis paves the
way for the design, experimental construction and validation of a new family of
functional genetic circuits for the purpose of calibrating promoters.Comment: 24 pages, 11 figure
Amuse-field. II. Nucleation of early-type galaxies in the field versus cluster environment
The optical light profiles of nearby early-type galaxies are known to exhibit a smooth transition from nuclear light deficits to nuclear light excesses with decreasing galaxy mass, with as much as 80% of the galaxies with stellar masses below 1010 M ? hosting a massive nuclear star cluster (NSC). At the same time, while all massive galaxies are thought to harbor nuclear supermassive black holes (SMBHs), observational evidence for SMBHs is slim at the low end of the mass function. Here, we explore the environmental dependence of the nucleation fraction by comparing two homogeneous samples of nearby field versus cluster early-type galaxies with uniform Hubble Space Telescope (HST) coverage. Existing Chandra X-ray Telescope data for both samples yield complementary information on low-level accretion onto nuclear SMBHs. Specifically, we report on dual-band (F475W and F850LP) Advanced Camera for Surveys (ACS) imaging data for 28 out of the 103 field early-type galaxies that compose the AMUSE-Field Chandra survey, and compare our results against the companion HST and Chandra surveys for a sample of 100 Virgo Cluster early-types (ACS Virgo Cluster and AMUSE-Virgo surveys, respectively). We model the two-dimensional light profiles of the field targets to identify and characterize NSCs, and find a field nucleation fraction of 26% +17%-11% (at the 1s level), consistent with the measured Virgo nucleation fraction across a comparable mass distribution (30%+17%-12%). Coupled with the Chandra result that SMBH activity is higher for the field, our findings indicate that, since the last epoch of star formation, the funneling of gas to the nuclear regions has been inhibited more effectively for Virgo galaxies, arguably via ram pressure stripping
The celebrity entrepreneur on television: profile, politics and power
This article examines the rise of the âcelebrity entrepreneurâ on television through the emergence of the âbusiness entertainment formatâ and considers the ways in which regular television exposure can be converted into political influence. Within television studies there has been a preoccupation in recent years with how lifestyle and reality formats work to transform âordinaryâ people into celebrities. As a result, the contribution of vocationally skilled business professionals to factual entertainment programming has gone almost unnoticed. This article draws on interviews with key media industry professionals and begins by looking at the construction of entrepreneurs as different types of television personalities and how discourses of work, skill and knowledge function in business shows. It then outlines how entrepreneurs can utilize their newly acquired televisual skills to cultivate a wider media profile and secure various forms of political access and influence. Integral to this is the centrality of public relations and media management agencies in shaping media discourses and developing the individual as a âbrand identityâ that can be used to endorse a range of products or ideas. This has led to policy makers and politicians attempting to mobilize the media profile of celebrity entrepreneurs to reach out and connect with the public on business and enterprise-related issues
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