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Right Temporoparietal Junction Involvement in Autonomic Responses to the Suffering of Others: A Preliminary Transcranial Magnetic Stimulation Study.
Functional neuroimaging studies have emphasized distinct networks for social cognition and affective aspects of empathy. However, studies have not considered whether substrates of social cognition, such as the right temporoparietal junction (TPJ), play a role in affective responses to complex empathy-related stimuli. Here, we used repetitive transcranial magnetic stimulation (TMS) to test whether the right TPJ contributes to psychophysiological responses to another person's emotional suffering. We used a theory of mind functional localizer and image-guided TMS to target the sub-region of the right TPJ implicated in social cognition, and measured autonomic and subjective responses to an empathy induction video. We found evidence that TMS applied at 1 Hz over the right TPJ increased withdrawal of parasympathetic nervous system activity during the empathy induction (n = 32), but did not affect sympathetic nervous system activity (n = 27). Participants who received TMS over the right TPJ also reported feeling more irritation and annoyance, and were less likely to report feeling compassion over and above empathic sadness, than participants who received TMS over the vertex (N = 34). This study provides preliminary evidence for the role of right TPJ functioning in empathy-related psychophysiological and affective responding, potentially blurring the distinction between neural regions specific to social cognition vs. affective aspects of empathy
A dual-polarized quasi-optical SIS mixer at 550 GHz
In this paper, we describe the design, fabrication, and the performance of a low-noise dual-polarized quasi-optical superconductor-insulator-superconductor (SIS) mixer at 550 GHz. The mixer utilizes a novel cross-slot antenna on a hyperhemispherical substrate lens, two junction tuning circuits, niobium trilayer junctions, and an IF circuit containing a lumped element 180° hybrid. The antenna consists of an orthogonal pair of twin-slot antennas, and has four feed points, two for each polarization. Each feed point is coupled to a two-junction SIS mixer. The 180° IF hybrid is implemented using a lumped element/microstrip circuit located inside the mixer block. Fourier transform spectrometer measurements of the mixer frequency response show good agreement with computer simulations. The measured co-polarized and cross-polarized patterns for both polarizations also agree with the theoretical predictions. The noise performance of the dual-polarized mixer is excellent giving uncorrected receiver noise temperature of better than 115 K (double sideband) at 528 GHz for both the polarizations
A 530-GHz balanced mixer
We report on the design and performance of a 530-GHz balanced SIS mixer, the first balanced mixer in this frequency range. This quasi-optical balanced mixer utilizes a cross-slot antenna on a hyperhemispherical substrate lens with eight superconductor-insulator-superconductor (SIS) junctions and a 180° lumped element IF hybrid circuit. The local oscillator (LO) and the radio frequency (RF) signal, orthogonal in polarization to each other, are coupled to the mixer using a wire-grid polarizer. The noise performance of the mixer is excellent, giving an uncorrected receiver noise temperature of 105 K (DSB) at 528 GHz
Characterization of low-noise quasi-optical SIS mixers for the submillimeter band
We report on the development of low-noise quasi-optical SIS mixers for the frequency range 400-850 GHz. The mixers utilize twin-slot antennas, two-junction tuning circuits, and Nb-trilayer junctions. Fourier-transform spectrometry has been used to verify that the frequency response of the devices is well predicted by computer simulations. The 400-850 GHz frequency band can be covered with four separate fixed-tuned mixers. We measure uncorrected double-sideband receiver noise temperatures around 5hΜ/kB to 700 GHz, and better than 540 K at 808 GHz. These results are among the best reported to date for broadband heterodyne receivers
Very high-current-density Nb/AlN/Nb tunnel junctions for low-noise submillimeter mixers
We have fabricated and tested submillimeter-wave superconductorâinsulatorâsuperconductor (SIS) mixers using very high-current-density Nb/AlN/Nb tunnel junctions (Jc[approximate]30 kA cmâ2). The junctions have low-resistance-area products (RNA[approximate]5.6 Omega ”m2), good subgap-to-normal resistance ratios Rsg/RN[approximate]10, and good run-to-run reproducibility. From Fourier transform spectrometer measurements, we infer that omegaRNC = 1 at 270 GHz. This is a factor of 2.5 improvement over what is generally available with Nb/AlOx/Nb junctions suitable for low-noise mixers. The AlN-barrier junctions are indeed capable of low-noise operation: we measure an uncorrected double-sideband receiver noise temperature of TRX = 110 K at 533 GHz for an unoptimized device. In addition to providing wider bandwidth operation at lower frequencies, the AlN-barrier junctions will considerably improve the performance of THz SIS mixers by reducing rf loss in the tuning circuits
Measurement of loss in superconducting microstrip at millimeter-wave frequencies
We have developed a new technique for accurate measurement of the loss of superconducting microstrips at mm-wave frequencies. In this technique, we optically couple power to slot antenna, which is connected to one port of a hybrid coupler. One of the output ports of the hybrid delivers power to a series of mm-wave microstrip resonators which are capacitively coupled to a feedline followed by an MKID (microwave kinetic inductance detector) that measures the transmitted power. Two other MKIDs are connected to the remaining ports of the hybrid to measure the total incident optical power and the power reflected from the mm-wave resonators, allowing |S_(21)|^2 and |S_(11)|^2 to be accurately determined and resonance frequency fr and quality factor Q to be retrieved. We have fabricated such a Nb/SiO_2/Nb microstrip loss test device which contains several mm- wave resonators with f_r~100 GHz and measured it at 30 mK. All the resonators have shown internal quality factor Qi~500â2000, suggesting a loss tangent of ~5Ă10^(â4)â2Ă10^(â3) for the SiO_2 in use. For comparison, we have also fabricated a 5 GHz microstrip resonator on the same chip and measured it with a network analyzer. The loss tangent at 5 GHz derived from fitting the f_0 and Q data to the two-level system (TLS) model is 6Ă10^(â4), about the same as from the mm-wave measurement. This suggests that the loss at both microwave and mm-wave frequencies is probably dominated by the TLS in SiO_2. Our results are of direct interest to mm/submm direct detection applications which use microstrip transmission lines (such as antenna-coupled MKIDs and transition-edge sensors), and other applications (such as on-chip filters). Our measurement technique is applicable up to approximately 1 THz and can be used to investigate a range of dielectrics
On the Developer Adoption of Scrum: A New Acceptance Model for Agile Methodologies
In recent years, the agile Scrum methodology has become a popular software development approach. It significantly differs from traditional approaches as it promotes communication, self-organization, flexibility, and innovation instead of extensive planning and codified processes. While such a paradigm shift promises to better support the timely delivery of high-quality software in turbulent business environments, its success considerably depends on the willingness of developers to adopt the agile methodology. In this paper, we present a framework with drivers and inhibitors to the developer acceptance of Scrum. It combines analytical with empirical findings and can be used as a theoretical basis to empirically evaluate the actual support of Scrum in concrete scenarios. The introduced framework is based on the extended Technology Acceptance Model (TAM), which has been proven to be also applicable to describe the intention of developers to use a methodology. Building upon results from qualitative in-depth interviews with six experienced Scrum experts of a German DAX-30 company, we refine the general determinants of adoption contained in the TAM with several observed factors that influence the willingness of developers to use Scrum in practice
Neural bases of social feedback processing and selfâother distinction in late childhood: The role of attachment and age
Attachment plays a key role in how children process information about the self and others. Here, we examined the neural bases of interindividual differences in attachment in late childhood and tested whether social cognition-related neural activity varies as function of age. In a small sample of 8-year-old to 12-year-old children (n = 21/19), we used functional magnetic resonance imaging to measure neural responses during social feedback processing and selfâother distinction. Attachment was assessed using child self-report. The social feedback processing task presented smiling and angry faces either confirming or disconfirming written information about participant performance on a perceptual game. In addition to observing main effects of facial emotion and performance, an increase in age was related to a shift from negative (i.e., angry faces/bad performance) to positive (i.e., smiling faces/good performance) information processing in the left amygdala/hippocampus, bilateral fusiform face area, bilateral anterior temporal pole (ATP), and left anterior insula. There were no effects of attachment on social feedback processing. The selfâother distinction task presented digital morphs between childrenâs own faces and faces of their mother or stranger females. We observed differential activation in face processing and mentalizing regions in response to self and mother faces versus morphed faces. Furthermore, left ATP activity was associated with attachment anxiety such that greater attachment anxiety was related to a shift from heightened processing of self and mother faces to morphed faces. There were no effects of age on selfâother distinction. We discuss our preliminary findings in the context of attachment theory and previous work on social evaluation and selfâother processing
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