543 research outputs found

    Returning to Learning: Adults' Success in College Is Key to America's Future

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    Provides an overview of research on adult learners' characteristics, risk factors, and needs at four-year institutions and in for-credit and non-credit courses, and what changes institutions and governments can implement to help adult students succeed

    Receding horizon control of vectored thrust flight experiment

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    Abstract: The application of a constrained receding horizon control technique to stabilise an indoor vectored-thrust flight experiment, known as the Caltech ducted fan, is given. The receding horizon control problem is formulated as a constrained optimal control problem and solved in real time with an efficient, computational method that combines nonlinear control theory, B-spline basis functions, and nonlinear programming. Characteristic issues, including non-zero computational times, convergence properties, choice of horizon length and terminal cost are discussed. The study validates the applicability of real-time receding horizon control for constrained systems with fast dynamics

    Results of investigations on a 0.015-scale model 2A configuration of the Rockwell International space shuttle orbiter in the NASA/Ames Research Center 3.5 foot hypersonic wind tunnel

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    Experimental aerodynamic investigations were conducted in the NASA/Ames 3.5-Foot Hypersonic wind Tunnel during the interim April 9-18, 1973 on a 0.015-scale model of the Rockwell International Space Shuttle Orbiter, configuration 2A. Six component aerodynamic force and moment data were recorded over an angle of attack range from -3 deg to 42 deg at 0 deg angle of sideslip and from -10 deg to 10 deg sideslip at 0 deg and 45 deg constant angle of attack. Test Mach numbers were 5.27 and 7.32 at unit Reynolds number of 2.5 million per foot. Various elevon, rudder, speedbrake, and body flap deflections were tested to determine longitudinal and lateral-directional stability characteristics and to establish trim capability

    Formation of Nucleobases from the UV Photo-Irradiation of Pyrimidine in Astrophysical Ice Analogs

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    Astrochemistry laboratory simulations have shown that complex organic molecules including compounds of astrobiological interest can be formed under interstellarl/circumstellar conditions from the vacuum UV irradiation of astrophysical ice analogs containing H2O, CO, CO2, CH3OH, NH13, etc. Of all prebiotic compounds, the formation of amino acids under such experimental conditions has been the most extensively studied. Although the presence of amino acids in the interstellar medium (ISM) has yet to be confirmed, they have been detected in meteorites, indicating that biomolecules and/or their precursors can be formed under extraterrestrial, abiotic conditions. Nucleobases, the building blocks of DNA and RNA, as well as other 1V-heterocycles, have also been detected in meteorites, but like amino acids, they have yet to be observed in the ISM. In this work, we present an experimental study of the formation of pyrimidine-based compounds from the UV photo-irradiation of pyrimidine in ice mixtures containing H2O, NH3, and/or CH3OH at low temperature and pressure

    Resident Corneal Cells Communicate with Neutrophils Leading to the Production of IP-10 during the Primary Inflammatory Response to HSV-1 Infection

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    In this study we show that murine and human neutrophils are capable of secreting IP-10 in response to communication from the HSV-1 infected cornea and that they do so in a time frame associated with the recruitment of CD8+ T cells and CXCR3-expressing cells. Cellular markers were used to establish that neutrophil influx corresponded in time to peak IP-10 production, and cellular depletion confirmed neutrophils to be a significant source of IP-10 during HSV-1 corneal infection in mice. A novel ex vivo model for human corneal tissue infection with HSV-1 was used to confirm that cells resident in the cornea are also capable of stimulating neutrophils to secrete IP-10. Our results support the hypothesis that neutrophils play a key role in T-cell recruitment and control of viral replication during HSV-1 corneal infection through the production of the T-cell recruiting chemokine IP-10

    On the nature of the enigmatic object IRAS 19312+1950: A rare phase of massive star formation?

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    IRAS 19312+1950 is a peculiar object that has eluded firm characterization since its discovery, with combined maser properties similar to an evolved star and a young stellar object (YSO). To help determine its true nature, we obtained infrared spectra of IRAS 19312+1950 in the range 5-550 μ\mum using the Herschel and Spitzer space observatories. The Herschel PACS maps exhibit a compact, slightly asymmetric continuum source at 170 μ\mum, indicative of a large, dusty circumstellar envelope. The far-IR CO emission line spectrum reveals two gas temperature components: 0.22M\approx0.22M_{\odot} of material at 280±18280\pm18 K, and 1.6M\approx1.6M_{\odot} of material at 157±3157\pm3 K. The OI 63 μ\mum line is detected on-source but no significant emission from atomic ions was found. The HIFI observations display shocked, high-velocity gas with outflow speeds up to 90 km s1^{-1} along the line of sight. From Spitzer spectroscopy, we identify ice absorption bands due to H2_2O at 5.8 μ\mum and CO2_2 at 15 μ\mum. The spectral energy distribution is consistent with a massive, luminous (2×104L\sim2\times10^4L_{\odot}) central source surrounded by a dense, warm circumstellar disk and envelope of total mass 500\sim500-700M700M_{\odot}, with large bipolar outflow cavities. The combination of distinctive far-IR spectral features suggest that IRAS 19312+1950 should be classified as an accreting high-mass YSO rather than an evolved star. In light of this reclassification, IRAS 19312+1950 becomes only the 5th high-mass protostar known to exhibit SiO maser activity, and demonstrates that 18 cm OH maser line ratios may not be reliable observational discriminators between evolved stars and YSOs.Comment: 16 pages. Accepted for publication in Ap

    JWST observations of stellar occultations by solar system bodies and rings

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    In this paper we investigate the opportunities provided by the James Webb Space Telescope (JWST) for significant scientific advances in the study of solar system bodies and rings using stellar occultations. The strengths and weaknesses of the stellar occultation technique are evaluated in light of JWST's unique capabilities. We identify several possible JWST occultation events by minor bodies and rings, and evaluate their potential scientific value. These predictions depend critically on accurate a priori knowledge of the orbit of JWST near the Sun-Earth Lagrange-point 2 (L2). We also explore the possibility of serendipitous stellar occultations by very small minor bodies as a by-product of other JWST observing programs. Finally, to optimize the potential scientific return of stellar occultation observations, we identify several characteristics of JWST's orbit and instrumentation that should be taken into account during JWST's development.Comment: This paper is one of a series for a special issue on Solar System observations with JWST in PASP. Accepted 2-Oct-2015. Preprint 30 pages, 5 tables, 8 figure
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