487 research outputs found

    Enseñar literatura a través del cuento: propuesta práctica para un aula de educación secundaria obligatoria

    Get PDF
    A lo largo de los años, la literatura ha sufrido una evolución paulatina de acuerdo a los diferentes momentos históricos, de modo que en la Educación también es posible observar la consecuencia de los cambios. Esto se percibe no solo en las lecturas escogidas por los docentes sino también en la manera de enseñar literatura. El cuento es uno de los géneros que se ha utilizado desde hace años como lectura en Educación Primaria debido a su actual carácter infantil. No obstante, se trata de un género narrativo a través del cual es posible enseñar diversos aspectos de la literatura en niveles más avanzados, como bien puede ser la Educación Secundaria. Esto es posible porque resulta un material didáctico realmente interesantes debido a su valor histórico y literario.Throughout the years, literature has undergone a gradual evolution according to different historical moments, so that it is possible to observe changes consequence in Education too. This can be perceived not only in school readings chosen by teachers but also in the way literature is taught. The story is a genre that have been used for years as a reading in Primary Education due to its current childish classification. However, it is a narrative genre whereby it is possible to teach different literature elements at more advanced levels such as Secondary Education. This results from the fact that it is a really interesting didactical material due to its historical and literary value

    Sistema de gestión energético óptimo para edificios inteligentes con sistemas de generación renovable integrados

    Get PDF
    Como solución para los nuevos edificios que desean adquirir la etiqueta de “edificios inteligentes” proponemos un software de gestión energética optima. Se trata de un sistema centralizado capaz de gestionar elementos de generación (por ejemplo, unidades de generación renovables integradas en el edificio), un sistema de almacenamiento y los distintos tipos de demanda que puede generar dicho edificio. Con el objetivo de un control energético total, el sistema consta de tres niveles distintos de gestión y a su vez, con tres modos de funcionamiento diferentes. Para demostrar el funcionamiento de esta herramienta se incluyen los resultados sobre un escenario emulado que consta de una pequeña generación solar, de tres niveles distintos de demanda propia y la demanda de un vehículo eléctrico que a su vez podrá servir de almacenaje energético mientras este permanezca aparcado.Peer ReviewedPostprint (author’s final draft

    Seasonal occurrence of different Grasshoppers species (Orthoptera: Acridoidea) in Uruguay

    Get PDF
    This paper aims at knowing the seasonal occurrence of grasshoppers (Orthoptera: Acridoidea) in Uruguay. The populations of these native herbivores are generally in equilibrium, although population increases were recorded under certain conditions, causing significant economic loss. The population was monitored during five seasons on sites located in the departments of Florida and Durazno. The insects were categorized into young nymphs (I, II and III), older nymphs (IV and V), and adults. At each sampling time, data from the different sites were grouped to calculate the percentage of each category. Twenty-six species were collected, eight of which were abundant. Borellia bruneri (Rehn, 1906), B. pallida (Bruner, 1900), Dichroplus pratensis Bruner, 1900 and D. elongatus Giglio-Tos, 1894 proved to be univoltine. More than one generation of Baeacris pseudopunctulatus (Ronderos, 1964), Orphulella punctata (De Geer, 1773), Scotussa lemniscata (Stål, 1861) and D. conspersus Bruner, 1900, was recorded per year in some seasons. The first births of B. bruneri, B. pallida, D. pratensis, D. conspersus, S. lemniscata and B. pseudopunctulatus occurred in October, whereas for D. elongatus and O. punctata they happened in November. Considering the eight species, young and older nymphs predominated until early December and from late December to early January, respectively. Adulthood was predominant since the end of January. These results are the basis for establishing a monitoring plan. In order to determine the need for control and to avoid irreparable loss, samples must be intensified from early November to the beginning of December, when the young nymphs are no longer predominant

    A qualitative study about changes that parents experience through a pilot parenting support program to improve the quality of contact visits in non-kinship foster care

    Get PDF
    Despite the important impact that contact with birth parents during non-kinship foster care can have on a child’s well-being, there are few psychoeducational programs aimed at improving the quality of visits. The purpose of this study was to analyze the perceptions of changes in birth parents who have completed the first program of this kind to be developed in Spain, here in its pilot application. The aim of the program Visits: a context for family development is to improve parents’ emotional, communication, and parenting competences, and it comprises a total of seven sessions: six individual sessions that take place in the hour prior to consecutive scheduled visits with the child, and one group session involving all participating birth parents. A total of five families began the program, and three mothers completed all seven sessions. We conducted semi-structured interviews with mothers before and after the intervention so as to explore their perceptions regarding changes in their parenting competences and the quality of visits with their child. These data were complemented by participant-observer notes taken by one of the researchers during program sessions. Through content and semantic network analysis of interviews, we were able to identify changes in relation to five aspects of contact visits following participation in the parenting program. The results suggest that the program has the potential to enhance the parenting competences of birth mothers, to improve parentchild interaction during contact visits, and to encourage collaboration between the birth and foster families. These preliminary findings support the utility of the program for improving the quality of contact visits between birth parents and their children in non-kinship foster care.This study is part of an R + D Project of Excellence financed by the Spanish government (EDU201677094-P) [Proyecto I + D de Fomento de la Investigaci ón Científica y T écnica de Excelencia]. Funding for open access charge: Universidad de M ́alaga / CBUA. Funding for open access charge: Universidad de Málaga / CBU

    Prognostic and Clinicopathological Significance of CCND1/Cyclin D1 Upregulation in Melanomas: A Systematic Review and Comprehensive Meta-Analysis

    Get PDF
    We would like to thank the research group CTS-392 (Plan Andaluz de Investigación, Junta de Andalucía, Spain).Simple Summary The incidence of cutaneous melanoma is increasing worldwide, currently responsible for 287,723 new cases and 60,712 deaths per year (GLOBOCAN, IARC, WHO). It should be also highlighted that some less frequent subtypes of melanomas-i.e., acral, uveal, and mucous melanoma-are responsible for significant morbidity associated with metastasis, responding typically worse to newer therapies. Therefore, new biomarkers are needed to improve the prognosis in individual patients. In this sense, the present study showed that CCND1/cyclin D1 upregulation is a common molecular oncogenic alteration in melanomas that probably favors the growth and expansion on cutaneous primary melanomas. Furthermore, immunohistochemical cyclin D1 overexpression strongly predicted a higher Breslow thickness, currently considered the most relevant prognostic factor in individual patients with melanomas. Finally, special attention should be paid to the CCND1/cyclin D1 complex in mucosal melanomas, whose upregulation was strikingly altered. Our objective was to evaluate the prognostic and clinicopathological significance of cyclin D1 (CD1) overexpression/CCND1 amplification in melanomas. We searched studies published before September 2019 (PubMed, Embase, Web of Science, Scopus). We evaluated the quality of the studies included (QUIPS tool). The impact of CD1 overexpression/CCND1 amplification on overall survival and relevant clinicopathological characteristic were meta-analyzed. We performed heterogeneity, sensitivity, small-study effects, and subgroup analyses. Forty-one studies and 3451 patients met inclusion criteria. Qualitative evaluation demonstrated that not all studies were performed with the same rigor, finding the greatest risk of bias in the study confounding domain. Quantitative evaluation showed that immunohistochemical CD1 overexpression had a statistical association with Breslow thickness (p = 0.007; OR = 2.09,95% CI = 1.23-3.57), significantly higher frequency of CCND1/cyclin D1 abnormalities has been observed in the primary tumor compared to distant metastases (p = 0.004), revealed also by immunohistochemical overexpression of the protein (p < 0.001; OR = 0.53,95% CI = 0.40-0.71), while the CCND1 gene amplification does not show association (p = 0.43); while gene amplification, on the contrary, appeared more frequently in distant metastases (p = 0.04; OR = 1.70,95% CI = 1.01-2.85) and not in the primary tumor. In conclusion, CCND1/cyclin D1 upregulation is a common molecular oncogenic alteration in melanomas that probably favors the growth and expansion of the primary tumor. This upregulation is mainly consequence to the overexpression of the cyclin D1 protein, and not to gene amplification

    3‐(Pyridin‐2‐yl)imidazo[1,5‐a]pyridine (Pyridylindolizine) as Ligand in Complexes of Transition and Main‐Group Metals

    Get PDF
    Producción CientíficaThe coordination of the easily prepared 3‐(pyridin‐2‐yl)imidazo[1,5‐a]pyridine (pyridylindolizine, Py‐indz) ligand to several metal moieties was studied, and its electronic properties, similar to those of the classical ligands 2,2′‐bipyridine (bipy) and 1,10‐phenanthroline (phen), are reported. The new complexes were prepared and fully characterized by X‐ray crystallography and other typical spectroscopic methods if possible. Paramagnetic complexes [Ni(S2X)2(Py‐indz)] X = P(OEt)2 (1), COEt (2); [Ni(acac)2(Py‐indz)] (3, acac = acetylacetonate); [Ni(Py‐indz)3](PF6)2 (4); [Mn2Cl4(Py‐indz)2] (6); and [MnCl2(Py‐indz)2] (7) have the magnetic moment expected for a metallic cation with two or five unpaired electrons. Diamagnetic complexes show NMR spectra with similar patterns with small differences depending on the complex. [M{S2P(OEt)2}2 (Py‐indz)] M = Zn (8), Cd (9) have pentacoordinate and hexacoordinate structures, respectively. Octahedral tin complexes [SnL4(Py‐indz)] L4 = I4 (10), Cl3Ph (11), and Cl2nBu2 (12) have different behaviors in solution; whereas complex 10 is practically insoluble, complex 11 displays the expected pattern in its NMR spectrum, and complex 12 shows dynamic behavior. The Py‐indz ligand is also able to stabilize copper(I) and forms [Cu(PPh3)2(Py‐indz)]BF4 (13). The synthesis of the carbonyl complexes [MBr(CO)3(Py‐indz)] M = Mn (14), Re (15) and [Mo(CO)4(Py‐indz)] (16) was followed by IR spectroscopy in solution. [RuCl·p‐cym(Py‐indz)]PF6 (17, p‐cym = p‐cymene) has the familiar half‐sandwich “three‐legged piano‐stool” geometry.Ministerio de Economía, Industria y Competitividad (Project CTQ2013- 41067-P

    Antiviral activity of ribosome-inactivating proteins

    Get PDF
    Producción CientíficaRibosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2.2.22) that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs have been investigated for more than four decades. However, interest in these proteins is rising due to the emergence of infectious diseases caused by new viruses and the difficulty in treating viral infections. On the other hand, there is a growing need to control crop diseases without resorting to the use of phytosanitary products which are very harmful to the environment and in this respect, RIPs have been shown as a promising tool that can be used to obtain transgenic plants resistant to viruses. The way in which RIPs exert their antiviral effect continues to be the subject of intense research and several mechanisms of action have been proposed. The purpose of this review is to examine the research studies that deal with this matter, placing special emphasis on the most recent findings.Junta de Castilla y León - (Grant VA033G19

    Features of non-kinship foster care children with birth family contact in Andalusia

    Get PDF
    The aim of the presentation is to describe the personal features of non-kinship foster care children who have visits with their birth family in Málaga, Granada and Jaén (provinces of Andalusia, Spain). This study was funded by the research project Application of a psychoeducational intervention program to improve visits between foster children and their biological families (Reference EDU2016 77094-P). SPSS v.21.0 was used to carry out the descriptive and frequency analysis of socio-demographic information collected by the Child File Summary Form designed for this study. There are 212 non-kinship foster care children who have visits with their birth family. Their mean age is 8.09 years old (SD= 4.73). The more frequent types of foster care are both long-term and short-term placement (30.7%, respectively), followed by specialized long-term foster care (20.3%), urgency placement (10.8%) and specialized short-term foster care (7.5%). The period of time they have been into the Child Protection System is on average 4.08 years (SD= 3.88) and into the current placement is on average 2.53 (SD= 2.95). Thus, 44.8% of foster children were in residential care and 30.2% were in previous foster care. The latter could have been with the current foster care family. Also, 41.0% of foster children were placed at least with one sibling. It is important to know the features of foster children in order to apply the main principle of “the best interests of the child” to the whole decision-making process about the child’s protection and welfare. In our project, these decisions concern foster care placement and birth family contact to maintain and strengthen family affective bonds and child’s identity formation. Our findings contribute to develop: (a) initiatives to improve children’s well-being; (b) support and social resources required by families; and (c) socio-educative tools for the social workers.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Oral health in the elderly patient and its impact on general well-being: a nonsystematic review

    Get PDF
    Data on the oral health of the elderly depict a worrying situation, with an elevated prevalence of caries and moderate periodontal disease, frequent edentulism, and numerous cases of dry mouth and oral cancer. There is wide evidence that periodontitis is a risk factor for certain systemic diseases, and impaired oral health has been associated with mastication and nutritional problems, especially among the elderly, with highly negative effects on their quality of life. In this nonsystematic review, the authors discuss the importance of evaluating the oral health of the geriatric population in a comprehensive manner, beyond simple clinical assessments

    Features of birth families with foster children in Andalusia

    Get PDF
    The aim of the presentation is to describe the personal features of biological families whose children are in non-kinship foster care and with whom they have face-to-face contact in Málaga, Granada and Jaén (provinces of Andalusia, Spain). This study was funded by the research project Application of a psychoeducational intervention program to improve visits between foster children and their biological families (Reference EDU2016 77094-P). SPSS v.21.0 was used to carry out the descriptive and frequency analysis of socio-demographic information collected by the Child File Summary Form designed for this study. The results show the difficulties experienced by birth families to deal with the responsibility of parenthood. There is a high percentage of unemployment (54.5% mothers, 46.4% fathers), and a low level of education (61.7% uneducated mothers, 68.8% uneducated fathers). Furthermore, it is necessary to consider their diverse personal problems which undermine their competences to bring up and educate their children: substance abuse, mental health issues, mental disability and prison. Finally, the lack of relation between Social Services and birth families is highlighted. Knowing the circumstances of families at psychosocial risk permits to develop social policies that match with their specific necessities, by providing them the support and resources required, in line with Recommendation Rec(2006)19 of the Committee of Ministers to member states. Moreover, children and families’ rights have to be respected, such as their right to have contact to maintain and strengthen their affective bonds as part of their identity. These findings will contribute to design: (a) family intervention programs which allow parents to acquire the necessary parental skills; (b) support and educational tools for the social workers; and (c) projects to contribute to children’s well-being.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
    corecore