Simulación continua y discreta de un sistema de producción con inventario en proceso constante.

Los sistemas pull de control del flujo de los materiales en una línea de fabricación/montaje han demostrado su utilidad por la sencillez de su operativa y pocos requerimientos del sistema de información de la empresa así como por los resultados o

Sistemas de control push-pull. Un estudio comparativo.

Un aspecto fundamental a nivel operacional en los sistemas de producción es la obtención de la cantidad deseada de unidades a producir con la mínima cantidad de inventario en proceso. Para conseguirlo podemos optar por distintos sistemas de control de

Intrinsic noise and deviations from criticality in Boolean gene-regulatory networks

Gene regulatory networks can be successfully modeled as Boolean networks. A much discussed hypothesis says that such model networks reproduce empirical findings the best if they are tuned to operate at criticality, i.e. at the borderline between their ordered and disordered phases. Critical networks have been argued to lead to a number of functional advantages such as maximal dynamical range, maximal sensitivity to environmental changes, as well as to an excellent tradeoff between stability and flexibility. Here, we study the effect of noise within the context of Boolean networks trained to learn complex tasks under supervision. We verify that quasi-critical networks are the ones learning in the fastest possible way –even for asynchronous updating rules– and that the larger the task complexity the smaller the distance to criticality. On the other hand, when additional sources of intrinsic noise in the network states and/or in its wiring pattern are introduced, the optimally performing networks become clearly subcritical. These results suggest that in order to compensate for inherent stochasticity, regulatory and other type of biological networks might become subcritical rather than being critical, all the most if the task to be performed has limited complexity.Spanish-MINECO grant FIS2013-43201-P (FEDER funds) for financial suppor

Citizen science and its role in entomological research: study in Teatinos Campus (University of Málaga).

Climate crisis implies large-scale accelerated changes which research groups can’t tackle on their own. That’s why citizen science has become a tool with the potential to generate useful data that helps to reduce uncertainty about these dynamics. Citizen science is the scientific research that includes the collaboration of the non-specialized public, along with scientists and professionals. This research compares data obtained through citizen science with other experimental ones to verify their quality to be used in entomological biogeographic studies. Experimental data was obtained through seasonal sampling in different areas of the Teatinos Campus from University of Málaga, identifying the entomofauna at the family taxonomic rank. Citizen science data was obtained through the participation of the university community using the iNaturalist platform. Citizen science is limited by the size of the organisms and the quality of the photographs. The statistical test showed that no significant differences were found between the abundance data obtained experimentally and those that have the contribution of citizen science. However, Citizen Science provided interesting data in the presence/absence study that was not obtained with the experimental one. This can be very useful in detecting the presence of invasive species. The HortSost II project is financed by the II Plan Propio Smart-Campus of the University of Malaga.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Especificación del proceso de desarrollo de un sistema para la realización de tutorías virtuales como herramienta de ayuda en la consolidación de los criterios de Bolonia

The main objective of this work is to serve as help in the learning process of the student community in agreement with the new teaching philosophy established in the Spanish Universities for the adjustment of the different University studies to the programs baaed on credits and they centred in the necessary student effort for the attainment of the objectives of a program based on ECTS credits (European Credits Trnasfer System). The system described in this paper has as purpose the help in the student-teacher remote comminication by means of the simulation of the real dialogue developed along the academic course. This system commucicates in real time, from distant locations, a professor to one or several students registered in the subjects teaching by this professor. In this way, the system allows the student-teacher interaction with the purpose of simulating the real dialogue. Also, the system incorporates a tutorial manager, a calendar for the requesting, notification and to management of the tutorial, and a report tool for the tutorial register, dialogue pursuit and reports printing giving to the professor (and students) a high quality educational support.El objetivo principal de este trabajo es servir de ayuda en el proceso de aprendizaje de la comunidad estudiantil de acuerdo a la nueva filosofía de enseñanza que se está estableciendo en las Universidades Españolas para el ajuste de las curriculas de las diferentes titulaciones al programa de educación basado en créditos y centrado en la carga de trabajo del estudiante necesaria para la consecución de los objetivos de un programa de créditos ECTS (European Credits Transfer System). El sistema descrito en este trabajo tiene como propósito la ayuda en la comunicación a distancia profesor-alumno mediante la simulación de las tutorías presenciales que se desarrollan a lo largo del curso académico. Este sistema deberá poner en contacto desde ubicaciones distantes a un profesor y a uno o varios alumnos matriculados en las asignaturas impartidas por dicho profesor, en tiempo real y permitir la interacción entre ellos, con el fin de simular el proceso de diálogo de una tutoría presencial. Además, el sistema incorpora un gestor de tutorías, una agenda que se encarga de la petición, recordatorio y gestión de las mismas, y un gestor de informes que lleva a cabo el registro, seguimiento e impresión de informes aportando al profesor ( y alumnos) un material docente de alta calidad

Hyperspectral Imaging to Evaluate the Effect of IrrigationWater Salinity in Lettuce

Salinity is one of the most important stress factors in crop production, particularly in arid regions. This research focuses on the effect of salinity on the growth of lettuce plants; three solutions with different levels of salinity were considered and compared (S1 = 50, S2 = 100 and S3 = 150 mM NaCl) with a control solution (Ct = 0 mM NaCl). The osmotic potential and water content of the leaves were measured, and hyperspectral images of the surfaces of 40 leaves (10 leaves per treatment) were taken after two weeks of growth. The mean spectra of the leaves (n = 32,000) were pre-processed by means of a Savitzky–Golay algorithm and standard normal variate normalization. Principal component analysis was then performed on a calibration set of 28 mean spectra, yielding an initial model for salinity effect detection. A second model was subsequently proposed based on an index computing an approximation to the second derivative at the red edge region. Both models were applied to all the hyperspectral images to obtain the corresponding artificial images, distinguishing between the 28 that were used to extract the calibration mean spectra and the rest that constituted an external validation. Those virtual images were studied using analysis of variance in order to compare their ability for detecting salinity effects on the leaves. Both models showed significant differences between each salinity level, and the hyperspectral images allowed observations of the distribution of the salinity effects on the leaf surfaces, which were more intense in the areas distant from the veins. However, the index-based model is simpler and easier to apply because it is based solely on the reflectance at three different wavelengths, thus allowing for the implementation of less expensive multispectral devices.The funding of this work was supported by the MICINN through projects Multihort (AGL2008-05666-C02-01) and QualityLeaf (AGL2013-48529-R). LPF-TAGRALIA is part of the CEI Moncloa Campus. We acknowledge support by the CSIC Open Access Publication Initiative through its Unit of Information Resources for Research (URICI)

SISTEMA DE GESTIÓN DE TUTORÍAS VIRTUALES COMO SOPORTE DE LOS NUEVOS MODELOS EDUCATIVOS

RESUMENEn este trabajo se presenta una solución de apoyo al desarrollo de la docencia haciendo uso de las nuevas tecnologías informáticas. Este sistema permite el desarrollo de tutorías profesor-alumno de forma no presencial (virtual) incorporando un conjunto de herramientas que permiten un amplio abanico de interacciones en el desarrollo de las mismas. La integración de un Chat, una pizarra, y un deposito de almacenamiento en los cuales pueden interactuar de forma autónoma y colaborativa el profesor y uno o varios alumnos hace que el sistema desarrollado favorezca el desarrollo de las tutorías dentro del marco docente, soslayando los problemas de tiempo y calendario por el cual este recurso docente es escasamente utilizado por el alumnado.Además, el sistema incorpora un gestor de tutorías, una agenda, que se encarga de la petición, recordatorio y gestión de las mismas. Esta utilidad junto con un gestor de informes que lleva a cabo el seguimiento y registro de las tutorías para, opcionalmente, su registro impreso, aporta al profesor (y alumnos) un material docente de alta calidad. El uso de Java, XML, RMI en un entorno cliente-servidor permite la adaptabilidad del sistema desarrollado a diferentes plataformas y entornos docentes, lo que permitirá la evaluación, depuración y crecimiento del sistema.PALABRAS CLAVESTecnología educativa, Software educativo, Tutoría Virtual, Cliente-Servidor, Java, UML, XML y RM

Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study

[Background and aims] There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence.[Methods and results] A total 6527 out of the 7447 participants in the PREDIMED trial met our inclusion criteria. A validated frequency food questionnaire was used to measure alcohol consumption. Participants were classified as non-drinkers, Mediterranean alcohol drinking pattern (MADP) (10–30 g/d in men and 5–15 g/day in women, preferably red wine consumption with low spirits consumption), low-moderate drinking (<30 g/day men y and < 15 g/day women), and heavy drinking. We performed multivariable Cox regression models to estimate hazard ratios (HR) with 95% confidence intervals (95% CI) of incident AF according to alcohol drinking patterns. After a mean follow up of 4.4 years, 241 new incident AF cases were confirmed. Alcohol consumption was not associated to AF incidence among low-moderate drinkers (HR: 0.96; 95%CI: 0.67–1.37), adherents to MADP (HR: 1.15 95%CI: 0.75–1.75), or heavy drinkers (HR: 0.92; 95%CI: 0.53–1.58), compared with non-drinkers.[Conclusions] In a high cardiovascular risk adult population, a Mediterranean alcohol consumption pattern (low to moderate red wine consumption) was not associated with an increased incidence of AF.[Clinical trials] URL: http://www.controlled-trials.com. Unique identifier: ISRCTN35739639.PREDIMED trial was supported by the official funding agency for biomedical research of the Spanish government (Instituto de Salud Carlos III) RTIC G03/140 (Coordinator: Dr Estruch) and RTIC RD 06/0045 (Coordinator: Dr Martínez-González). We also acknowledge grants from the National Institutes of Health, United States (1R01HL118264-01); Fondo de Investigación Sanitaria– Fondo Europeo de Desarrollo Regional (PI04/0233, PI05/0976, PI07/0240, PI10/01407, PI10/02658, PI11/00049, PI11/02505 and AGL2010-22319-C03-03); Consejería de Salud de la Junta de Andalucía (PI0105/2007), and by the Generalitat Valenciana, Spain (ACOMP/2013/165 and ACOMP/2013/159)