STR-840: INVESTIGATION OF LIVE LOAD MOMENT AND SHEAR FOR THE DESIGN OF BRIDGE DECK SLAB CANTILEVERS WITH UNSTIFFENED EDGE OR BUILT WITH TL-5 BARRIER WALL

This study builds on the methods of analyses with respect to cantilever slabs in the Canadian Highway Bridge Design Code (CHBDC), and recommends new simplified equations for the intensity of the transverse moment and shear force at the base of the cantilever overhang due to applied vertical truck loading. A parametric study was conducted using finite-element modelling on bridge deck cantilevers with variable lengths and slab thicknesses. Different end stiffening arrangements were considered, including the presence of PL-3 barriers walls (recently renamed to TL-5) as well as the concrete curb supporting intermittent steel posts carrying the bridge railing. The barrier length changed from 3 to 12 m, while the cantilever length ranged from 1.0 to 3.75 m. The results of this study complement the empirical expressions developed by others to determine the minimum required factored moment and tensile force resistance at the deck-barrier junction, induced by horizontal railing loads. Further to presenting design charts and empirical equations based on a series of cantilever-barrier configurations, this study gives way to the development of a suitable procedure for designing the bridge deck slab

The Qatar 2022 World Cup warm-up: Football goal-scoring evolution in the last 14 FIFA World Cups (1966–2018)

The aim of this study was to elucidate pattern of attacking actions leading up to goal scoring during the 14 FIFA World Cups from 1966 to 2018. The study analysed 1881 goals scored during a total of 732 matches. We employed observational methodology design. Before goal analysis began, it was developed the observing protocol in which data related to selected variables, by system of notation, was entered after reviewing each individual goal scoring action. The analysis of all video material was carried out independently by four experienced examiners (three of them are Ph.D in sports science and one is Ph.D. candidate in sports science with at least 7 years of coaching and experience as analyst in football). The inter-and intra-observer reliability presented good level of agreement. The kappa values ranged from 0.82 (goal scoring through open play) to 1.00 (action leading up to goal), showing a very high agreement for all performance variables. Interclass correlation was very high (ICC = 0.966, 95% upper and lower confidence intervals were between 0.933 and 1.00). A statistically significant trend (p < 0.05) from 1966 to 2018 was identified towards a higher relative frequency of goals scored from set play and collective actions from open play. The Chi-square did not reveal significant differences in the frequency of goal scoring patterns and goal-scoring zones. The results also revealed that the majority of goals were scored between the 76th and 90th minutes of a match (22.7%), from open play (70.5%), inside the penalty area (54.7%), one touch finishing (62.5%), and collective attacks in open play (55.8%). These findings may provide a possible strategic direction for improving goal-scoring performance in football, as well as practical implementation in World Cup tournament preparation

Protection of suppliers of agricultural and food products from unfair trading practice

The paper analyses unfair trading practices that arise as a result of imbalance in bargaining power between suppliers and buyers of agricultural and food products. Considering that unfair practices also exist in the relations established between consumers and traders, that special rules have been adopted in this regard, the peculiarities and differences that exist between these rules were first pointed out, i.e., in terms of the approach to regulating these practices. Furthermore, the classification of unfair trade practices as absolutely and relatively prohibited was performed, and, finally, the rules on the way in which suppliers are protected from unfair practices were set out. Basically, the method of protection (administrative protection, at the initiative of the competent authorities or at the request of relevant organizations and associations) justifies the adoption of special rules that establish an effective system of protection of suppliers from unfair trading practices.Publishe

Structural requirements for ligands of the delta-opioid receptor

The delta-opioid receptor is sensitive to ligand geometry. In order to assist the synthesis of new delta-selective opioid ligands, the structure elements of delta-selective opioid ligands necessary for their effective binding were investigated. The automated docking procedure with a flexible ligand was used to simulate the binding of 17 delta-selective ligands to the delta-receptor. It was found that voluminous N-alkyl groups reduce the binding potency of naltrindole derivatives by preventing the ligands from adopting the preferred conformation in the receptor. This was confirmed by enantiospecific binding of chiral compounds where only one enantiomer adopts the naltrindole-like preferred conformation in the binding pocket. Voluminous groups replacing the hydroxyl group in the 3-hydroxybenzyl fragment of naltrindole analogs reduce the binding potency due to unfavorable steric interactions with the receptor. The two diastereoisomers of the potent delta-opioid ligand SNC80 confirmed the preferred binding conformation and the major receptor-ligand interactions

Forms of Politeness Within the Speech Act of Apologies Compared to the Parameter Gender in the English Language

The question of politeness in language has been one of the most popular in linguistic studies since the second half of the twentieth century, and as such, has intrigued us to make a presentation of forms of politeness in the speech act of apologies within the English language system. Interesting and complex at the same time, primarily due to the interweaving of grammar, psychology and sociolinguistics, this problem proved to be a huge challenge, asking for both theoretical and discussions of the results obtained in practice. This paper presents the results of a case study conducted on the corpus obtained from a popular reality show in order to show whether the women, and to what extent, tend to use more tentative language forms within the speech act of apologies. DOI: 10.5901/mjss.2014.v5n13p19

The economic and tourism valorization and legal protection of the villas of Vrnjačka Banja as the guardians of the cultural heritage

Conclusions of the Round Table organized by the Faculty of Hotel Management and Tourism in Vrnjačka Banja, within the Project "The Villas of Vrnjačka Banja as the Guardians of Cultural Heritage - ReVillas", funded by Serbian Academy of Sciences and Arts (SASA) Research Center in Kragujevac and the University of KragujevacPublishe

Retention force of polyetheretherketone and cobalt-chrome-molybdenum removable dental prosthesis clasps after artificial aging

Objectives: To examine the retention force of removable dental prosthesis (RDP) clasps made from polyetheretherketone (PEEK) and cobalt-chrome-molybdenum (CoCrMo, control group) after storage in water and artificial aging. Materials and methods: For each material, 15 Bonwill clasps with retentive buccal and reciprocal lingual arms situated between the second pre- and first molar were manufactured by milling (Dentokeep [PEEKmilled1], NT digital implant technology; breCAM BioHPP Blank [PEEKmilled2], bredent), pressing (BioHPP Granulat for 2 press [PEEKpressed], bredent), or casting (remanium GM 800+ [CoCrMo], Dentaurum); N = 60, n = 15/subgroup. A total of 50 retention force measurements were performed for each specimen per aging level (initial; after storage [30 days, 37 °C] and 10,000 thermal cycles; after storage [60 days, 37 °C] and 20,000 thermal cycles) in a pull-off test. Data were statistically analyzed using one-way ANOVA, post hoc Scheffé and mixed models (p < 0.05). Results: Initial, PEEKpressed (80.2 ± 35.2) and PEEKmilled1 (98.9 ± 40.3) presented the lowest results, while PEEKmilled2 (170.2 ± 51.8) showed the highest values. After artificial aging, the highest retention force was observed for the control group (131.4 ± 56.8). The influence of artificial aging was significantly higher for PEEK-based materials. While PEEKmilled2 and PEEKpressed showed an initial decline in retention force, all other groups presented no impact or an increase in retention force over a repetitive insertion and removal of the clasps. Conclusions: Within the tested PEEK materials, PEEKmilled2 presented superior results than PEEKpressed. Although CoCrMo showed higher values after artificial aging, all materials exhibited sufficient retention to recommend usage under clinical conditions. Clinical relevance: As RDPs are still employed for a wide range of indications, esthetic alternatives to conventional CoCrMo clasps are sought. Keywords: Clasp; Cobalt-chrome-molybdenum; PEEK; Removable dental prosthesis; Retention force

MMIC HEMT Power Amplifier for 140 to 170 GHz

A three-stage monolithic microwave integrated circuit (MMIC) power amplifier that features high-electron-mobility transistors (HEMTs) as gain elements is reviewed. This amplifier is designed to operate in the frequency range of 140 to 170 GHz, which contains spectral lines of several atmospheric molecular species plus subharmonics of other such spectral lines. Hence, this amplifier could serve as a prototype of amplifiers to be incorporated into heterodyne radiometers used in atmospheric science. The original intended purpose served by this amplifier is to boost the signal generated by a previously developed 164-GHz MMIC HEMT doubler and drive a 164-to-328-GHz doubler to provide a few milliwatts of power at 328 GHz

A biomanufacturing facility based on continuous processing and single use technology

Bayers vision of the Biofacility of the Future is developed within the Mobidik project. A pilot plant with a complete production line of monoclonal antibodies from fermentation to final drug substance has been established. All parts in contact with the product are made in single use technology and the process is run as an integrated, fully continuous process. The process control system and the PAT concept are developed to achieve a high level of automation limiting the need for manual handling to a minimum. Issues related to GMP compliance are being addressed at an early stage. A detailed GMP risk analysis and a concept for product release are being developed. The pilot plant is used to provide a proof of concept for the process technology and to lay the foundation for building a production plant with a capacity of 150 kg/a. In particular, the pilot plant is used to demonstrate process robustness and GMP readiness. The concept for the production plant is based on the four design criteria; 100% single use equipment, continuous processing, closed processing and “ballroom” production. Compared to traditional facilities this concept is significantly less complex which results in a number of benefits. The engineering, construction, commissioning, qualification and validation of the facility are much faster. Flexibility is achieved through the decoupling of the equipment from the building. The facility is smaller, has reduced investment and production cost as well as reduced energy and water consumption. It should therefore be possible to build the production facility in less than two years for less than 20 million €