On the interpretation of responses from hydrogel based distributed microbend fibre optic sensors

This contribution discuses the physicochemical aspects associated with the response of hydrogel based distributed fibre optic microbend sensors to different humidity conditions. We explain that the swelling of the hydrogel which leads to the observed change in the OTDR signal should be attributed to a change in the water potential of the hydrogel being at an equilibrium with the water potential of its immediate physicochemical environment. Since the water potential in the hydrogel matrix is the result of several equilibration processes from multiple species that are interacting in the immediate environment surrounding the sensor, the observed fibre deformation should be attributed to all of the components of the chemical potential. The work draws attention to the necessity to fully characterize the hydrogel system used in each sensing application. The analysis is of relevance to all types of fibre optic biosensors that utilize hydrogels in the measurement process

On the interpretation of responses from hydrogel based distributed microbend fibre optic sensors

This contribution discuses the physicochemical aspects associated with the response of hydrogel based distributed fibre optic microbend sensors to different humidity conditions. We explain that the swelling of the hydrogel which leads to the observed change in the OTDR signal should be attributed to a change in the water potential of the hydrogel being at an equilibrium with the water potential of its immediate physicochemical environment. Since the water potential in the hydrogel matrix is the result of several equilibration processes from multiple species that are interacting in the immediate environment surrounding the sensor, the observed fibre deformation should be attributed to all of the components of the chemical potential. The work draws attention to the necessity to fully characterize the hydrogel system used in each sensing application. The analysis is of relevance to all types of fibre optic biosensors that utilize hydrogels in the measurement process

Identifying defects in aerospace composite sandwich panels using high-definition distributed optical fibre sensors

Automated methods for detecting defects within composite materials are highly desirable in the drive to increase throughput, optimise repair program effectiveness and reduce component replacement. Tap-testing has traditionally been used for detecting defects but does not provide quantitative measurements, requiring secondary techniques such as ultrasound to certify components. This paper reports on an evaluation of the use of a distributed temperature measurement system—high-definition fibre optic sensing (HD-FOS)—to identify and characterise crushed core and disbond defects in carbon fibre reinforced polymer (CFRP)-skin, aluminium-core, sandwich panels. The objective is to identify these defects in a sandwich panel by measuring the heat transfer through the panel thickness. A heater mat is used to rapidly increase the temperature of the panel with the HD-FOS sensor positioned on the top surface, measuring temperature. HD-FOS measurements are made using the Luna optical distributed sensor interrogator (ODISI) 9100 system comprising a sensor fabricated using standard single mode fibre (SMF)-20 of external diameter 250 µm, including the cladding. Results show that areas in which defects are present modulate thermal conductivity, resulting in a lower surface temperature. The resultant data are analysed to identify the length, width and type of defect. The non-invasive technique is amenable to application in challenging operational settings, offering high-resolution visualisation and defect classification

Defect detection in aerospace sandwich composite panels using conductive thermography and contact sensors

Sandwich panels consisting of two Carbon Fibre Reinforced Polymer (CFRP) outer skins and an aluminium honeycomb core are a common structure of surfaces on commercial aircraft due to the beneficial strength–weight ratio. Mechanical defects such as a crushed honeycomb core, dis-bonds and delaminations in the outer skins and in the core occur routinely under normal use and are repaired during aerospace Maintenance, Repair and Overhaul (MRO) processes. Current practices rely heavily on manual inspection where it is possible minor defects are not identified prior to primary repair and are only addressed after initial repairs intensify the defects due to thermal expansion during high temperature curing. This paper reports on the development and characterisation of a technique based on conductive thermography implemented using an array of single point temperature sensors mounted on one surface of the panel and the concomitant induced thermal profile generated by a thermal stimulus on the opposing surface to identify such defects. Defects are classified by analysing the differential conduction of thermal energy profiles across the surface of the panel. Results indicate that crushed core and impact damage are detectable using a stepped temperature profile of 80 ∘C The method is amenable to integration within the existing drying cycle stage and reduces the costs of executing the overall process in terms of time-to-repair and manual effort

Specifying content and mechanisms of change in interventions to change professionals’ practice : an illustration from the Good Goals study in occupational therapy

PMID: 23078918 [PubMed - indexed for MEDLINE] PMCID: PMC3502268 Free PMC Article The study was funded by the Chief Scientist Office of the Scottish Government Health Directorates (ref: CZF/1/38). The views expressed in this paper are those of the authors. The funder was not involved in the conduct of the study or preparation of the manuscript.Peer reviewedPublisher PD

Patient-, organization-, and system-level barriers and facilitators to preventive oral health care:A convergent mixed-methods study in primary dental care

Background: Dental caries is the most common chronic disease of adult and childhood, a largely preventable yet widespread, costly public health problem. This study identified patient-, organization-, and system-level factors influencing routine delivery of recommended care for prevention and management of caries in primary dental care. Methods: A convergent mixed-methods design assessed six guidance-recommended behaviours to prevent and manage caries (recording risk, risk-based recall intervals, applying fluoride varnish, placing preventive fissure sealants, demonstrating oral health maintenance, taking dental x-rays). A diagnostic questionnaire assessing current practice, beliefs, and practice characteristics was sent to a random sample of 651 dentists in National Health Service (NHS) Scotland. Eight in-depth case studies comprising observation of routine dental visits and dental team member interviews were conducted. Patient feedback was collected from adult patients with recent checkups at case study practices. Key informant interviews were conducted with decision makers in policy, funding, education, and regulation. The Theoretical Domains Framework within the Behaviour Change Wheel was used to identify and describe patient-, organization-, and system-level barriers and facilitators to care. Findings were merged into a matrix describing theoretical domains salient to each behaviour. The matrix and Behaviour Change Wheel were used to prioritize behaviours for change and plan relevant intervention strategies. Results: Theoretical domains associated with best practice were identified from the questionnaire (N-196), case studies (N = 8 practices, 29 interviews), and patient feedback (N = 19). Using the study matrix, key stakeholders identified priority behaviours (use of preventive fissure sealants among 6–12-year-olds) and strategies (audit and feedback, patient informational campaign) to improve guidance implementation. Proposed strategies were assessed as appropriate for immediate implementation and suitable for development with remaining behaviours. Conclusions: Specific, theoretically based, testable interventions to improve caries prevention and management were coproduced by patient-, practice-, and policy-level stakeholders. Findings emphasize duality of behavioural determinants as barriers and facilitators, patient influence on preventive care delivery, and benefits of integrating multi-level interests when planning interventions in a dynamic, resource-constrained environment. Interventions identified in this study are actively being used to support ongoing implementation initiatives including guidance, professional development, and oral health promotion

A novel methodology for macroscale, thermal characterization of carbon fiber-reinforced polymer for integrated aircraft electrical power systems

Carbon fiber-reinforced polymer (CFRP) is increasingly used for aero-structure applications due to their high strength-to-weight ratio. The integration of the on-board electrical power system (EPS) with CFRP is challenging due to the requirement to thermally and electrically isolate these systems to meet existing safety standards. By capturing the thermal characteristics of CFRP at a macro (component) scale for CFRP components, it is possible to understand, and design for, the increased integration of the EPS into CFRP aero-components. A significant challenge is to develop a macroscale characterization of CFRP, which is not only of an appropriate fidelity for compatibility with systems-level models of an EPS but also can be used to represent different geometries of CFRP components. This paper presents a novel methodology for capturing a transient, macroscale thermal characterization of CFRP with regard to component layup and geometry (thickness). The methodology uses experimentally derived thermal responses of specific resin and ply orientation CFRP samples to create a generalized relationship for the prediction of thermal transfer in other sample thicknesses of the same material type. This methodology can be used to characterize thermal gradients across CFRP components in aircraft EPS integration applications, ultimately informing the optimized integration of the EPS with CFRP

Football fans in training: the development and optimization of an intervention delivered through professional sports clubs to help men lose weight, become more active and adopt healthier eating habits

<p>Background: The prevalence of obesity in men is rising, but they are less likely than women to engage in existing weight management programmes. The potential of professional sports club settings to engage men in health promotion activities is being increasingly recognised. This paper describes the development and optimization of the Football Fans in Training (FFIT) programme, which aims to help overweight men (many of them football supporters) lose weight through becoming more active and adopting healthier eating habits.</p> <p>Methods: The MRC Framework for the design and evaluation of complex interventions was used to guide programme development in two phases. In Phase 1, a multidisciplinary working group developed the pilot programme (p-FFIT) and used a scoping review to summarize previous research and identify the target population. Phase 2 involved a process evaluation of p-FFIT in 11 Scottish Premier League (SPL) clubs. Participant and coach feedback, focus group discussions and interviews explored the utility/acceptability of programme components and suggestions for changes. Programme session observations identified examples of good practice and problems/issues with delivery. Together, these findings informed redevelopment of the optimized programme (FFIT), whose components were mapped onto specific behaviour change techniques using an evidence-based taxonomy.</p> <p>Results: p-FFIT comprised 12, weekly, gender-sensitised, group-based weight management classroom and ‘pitch-side’ physical activity sessions. These in-stadia sessions were complemented by an incremental, pedometer-based walking programme. p-FFIT was targeted at men aged 35-65 years with body mass index ≥ 27 kg/m2. Phase 2 demonstrated that participants in p-FFIT were enthusiastic about both the classroom and physical activity components, and valued the camaraderie and peer-support offered by the programme. Coaches appreciated the simplicity of the key healthy eating and physical activity messages. Suggestions for improvements that were incorporated into the optimized FFIT programme included: more varied in-stadia physical activity with football-related components; post-programme weight management support (emails and a reunion session); and additional training for coaches in SMART goal setting and the pedometer-based walking programme.</p> <p>Conclusions: The Football Fans in Training programme is highly acceptable to participants and SPL coaches, and is appropriate for evaluation in a randomised controlled trial.</p&gt

Evaluating the clinical and cost effectiveness of a behaviour change intervention for lowering cardiovascular disease risk for people with severe mental illnesses in primary care (PRIMROSE study):study protocol for a cluster randomised controlled trial

BACKGROUND: People with severe mental illnesses die up to 20 years earlier than the general population, with cardiovascular disease being the leading cause of death. National guidelines recommend that the physical care of people with severe mental illnesses should be the responsibility of primary care; however, little is known about effective interventions to lower cardiovascular disease risk in this population and setting. Following extensive peer review, funding was secured from the United Kingdom National Institute for Health Research (NIHR) to deliver the proposed study. The aim of the trial is to test the effectiveness of a behavioural intervention to lower cardiovascular disease risk in people with severe mental illnesses in United Kingdom General Practices. METHODS/DESIGN: The study is a cluster randomised controlled trial in 70 GP practices for people with severe mental illnesses, aged 30 to 75 years old, with elevated cardiovascular disease risk factors. The trial will compare the effectiveness of a behavioural intervention designed to lower cardiovascular disease risk and delivered by a practice nurse or healthcare assistant, with standard care offered in General Practice. A total of 350 people will be recruited and followed up at 6 and 12 months. The primary outcome is total cholesterol level at the 12-month follow-up and secondary outcomes include blood pressure, body mass index, waist circumference, smoking status, quality of life, adherence to treatments and services and behavioural measures for diet, physical activity and alcohol use. An economic evaluation will be carried out to determine the cost effectiveness of the intervention compared with standard care. DISCUSSION: The results of this pragmatic trial will provide evidence on the clinical and cost effectiveness of the intervention on lowering total cholesterol and addressing multiple cardiovascular disease risk factors in people with severe mental illnesses in GP Practices. TRIAL REGISTRATION: Current Controlled Trials ISRCTN13762819 . Date of Registration: 25 February 2013. Date and Version Number: 27 August 2014 Version 5

Translating research into practice in Leeds and Bradford (TRiPLaB): a protocol for a programme of research

Background The National Institute for Health Research (NIHR) has funded nine Collaborations for Leadership in Applied Health Research and Care (CLAHRCs). Each CLAHRC is a partnership between higher education institutions (HEIs) and the NHS in nine UK regional health economies. The CLAHRC for Leeds, York, and Bradford comprises two 'research themes' and three 'implementation themes.' One of these implementation themes is Translating Research into Practice in Leeds and Bradford (TRiPLaB). TRiPLaB aims to develop, implement, and evaluate methods for inducing and sustaining the uptake of research knowledge into practice in order to improve the quality of health services for the people of Leeds and Bradford. Methods TRiPLaB is built around a three-stage, sequential, approach using separate, longitudinal case studies conducted with collaborating NHS organisations, TRiPLaB will select robust innovations to implement, conduct a theory-informed exploration of the local context using a variety of data collection and analytic methods, and synthesise the information collected to identify the key factors influencing the uptake and adoption of targeted innovations. This synthesis will inform the development of tailored, multifaceted, interventions designed to increase the translation of research findings into practice. Mixed research methods, including time series analysis, quasi-experimental comparison, and qualitative process evaluation, will be used to evaluate the impact of the implementation strategies deployed. Conclusion TRiPLaB is a theory-informed, systematic, mixed methods approach to developing and evaluating tailored implementation strategies aimed at increasing the translation of research-based findings into practice in one UK health economy. Through active collaboration with its local NHS, TRiPLaB aims to improve the quality of health services for the people of Leeds and Bradford and to contribute to research knowledge regarding the interaction between context and adoption behaviour in health services