190 research outputs found

    Towards a holographic realization of the quarkyonic phase

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    Large-N_c QCD matter at intermediate baryon density and low temperatures has been conjectured to be in the so-called quarkyonic phase, i.e., to have a quark Fermi surface and on top of it a confined spectrum of excitations. It has been suggested that the presence of the quark Fermi surface leads to a homogeneous phase with restored chiral symmetry, which is unstable towards creating condensates breaking both the chiral and translational symmetry. Motivated by these exotic features, we investigate properties of cold baryonic matter in the single flavor Sakai-Sugimoto model searching for a holographic realization of the quarkyonic phase. We use a simplified mean-field description and focus on the regime of parametrically large baryon densities, of the order of the square of the 't Hooft coupling, as they turn out to lead to new physical effects similar to the ones occurring in the quarkyonic phase. One effect, the appearance of a particular marginally stable mode breaking translational invariance and linked with the presence of the Chern-Simons term in the flavor brane Lagrangian, is known to occur in the deconfined phase of the Sakai-Sugimoto model, but turns out to be absent here. The other, completely new phenomenon that we, preliminarily, study using strong simplifying assumptions are density-enhanced interactions of the flavor brane gauge field with holographically represented baryons. These seem to significantly affect the spectrum of vector and axial mesons and might lead to approximate chiral symmetry restoration in the lowest part of the spectrum, where the mesons start to qualitatively behave like collective excitations of the dense baryonic medium. We discuss the relevance of these effects for holographic searches of the quarkyonic phase and conclude with a discussion of various subtleties involved in constructing a mean-field holographic description of a dense baryonic medium.Comment: 31 pages, 16 figures; v2: inset plot in Fig. 10 removed, coloring in Fig. 13 fixed, typos fixed, matches published versio

    Statistics of thermalization in Bjorken Flow

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    The apparent early thermalization of quark-gluon plasma produced at RHIC and LHC has motivated a number of studies of strongly coupled N=4{\mathcal N}=4 supersymmetric Yang-Mills theory using the AdS/CFT correspondence. Here we present the results of numerical simulations of Bjorken flow aimed at establishing typical features of the dynamics. This is done by evolving a large number of far from equilibrium initial states well into the hydrodynamic regime. The results strongly suggest that early thermalization is generic in this theory, taking place at proper times around 0.60.6 in units of inverse local temperature. We also find that the scale which determines the rate of hydrodynamic cooling is linearly correlated with the entropy of initial states defined by the area of the apparent horizon in the dual geometry. Our results also suggest that entropy production during the hydrodynamic stage of evolution is not negligible despite the low value of η/s\eta/s.Comment: Various small improvements, including additional references. Version to appear in JHE

    Volunteer Computing Simulation Using Repast And Mason

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    Volunteer environments usually consist of a large number of computing nodes,with highly dynamic characteristics, therefore reliable models for a planning ofthe whole computing are highly desired. An easy to implement approach to mo-delling and simulation of such environments may employ agent-based universalsimulation frameworks, such as RePast or MASON. In the course of the paperthe above-mentioned simulation frameworks are adapted to support simulationof volunteer computing. After giving implementation details, selected resultsconcerning computing time and speedup are given and are compared with theones obtained from an actual volunteer environment

    Meta-analysis of postoperative myocardial injury as a predictor of mortality after living donor liver transplantation

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    Background: The purpose of this study was to perform a systematic review and meta-analysis to investigate postoperative myocardial injury, as expressed by the postoperative concentration of high-sensitivity cardiac troponin I (hs-cTnI) as a predictor of mortality among living donor liver transplantation (LDLT) patients. Methods: PubMed, Scopus, Embase and the Cochrane Library were searched through to September 1st 2022. The primary endpoint included in-hospital mortality. Secondary endpoints were 1-year mortality and re-transplantation occurrence. Estimates are expressed as risk ratios (RRs) and 95% confidence intervals (95% CIs). Heterogeneity was assessed with the I2 test. Results: During the search, 2 studies were found that fit the criteria and had a total of 527 patients. Pooled analysis showed that in-hospital mortality in patients with myocardial injury was 9.9%, compared to 5.0% for patients without myocardial injury (RR = 3.01; 95% CI: 0.97–9.36; p = 0.06). Mortality among 1-year follow-up was 5.0% vs. 2.4%, respectively (RR = 1.90; 95% CI: 0.41–8.81; p = 0.41). Conclusions: In recipients with normal preoperative cTnI, myocardial injury LDLT may be associated with adverse clinical outcomes during a hospital stay, but the results were inconsistent at 1-year follow-up. Although routine follow-up of postoperative hs-cTnI, even in patients with normal preoperative levels, might still help predict the clinical outcome of LDLT. In future large and more representative studies are needed to establish the potential role of cTns in perioperative cardiac risk stratification

    Перебіг анемії вагітних у хворих на туберкульоз легень

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    В статье представлены данные течения анемии беременных и нарушения фетоплацентарного комплекса у 86 женщин, больных туберкулезом легких. Выявлено, что анемия на фоне туберкулезного процесса приводит к существенным функциональным и морфологическим нарушениям в плаценте. показано диагностическое значение оценки плацентарной дисфункции для профилактики и лечения анемии у данного контингента женщин.The article presents the data of course of pregnancy anemia and failures of fetoplacental complex in 86 women with pulmonary tuberculosis. It is found that anemia under tuberculous process leads to significant functional and morphological disturbances in placenta. Diagnostic significance of assessment of placental dysfunction for the prevention and treatment of anemia in this contingent of women is shown

    Systematic review and meta-analysis of the co-occurrence of atrial fibrillation and liver transplantation: a lethal combination

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    INTRODUCTION: This systematic review and meta-analysis is aimed to evaluate the role of new-onset atrial fibrillation (NOAF) in patients after liver transplantation (LT) and determine the effect of NOAF on the incidence of mortality and graft rejection. MATERIAL AND METHODS: Published studies until the end of April 15, 2023, were systematically searched in PubMed, Google Scholar, Scopus, Embase, Web of Science, and the Cochrane databases. Odds ratios (ORs) with 95% confidence intervals (CI) for mortality and graft rejection were extracted. RESULTS: Five studies with a total of 4788 unique post-LT patients were included in the meta-analysis. Pooled analysis showed that mortality in patients with and without NOAF varied and amounted to 24.1% vs. 12.5%, respectively (OR = 2.51; 95%CI: 1.92 to 3.27; p < 0.001). Moreover, pooled analysis showed that graft rejection in the NOAF cohort was 26.3%, and was higher vs. patients without NOAF (13.1%; OR = 2.98; 95%CI: 2.14 to 4.15; p < 0.001) CONCLUSIONS: Post-LT NOAF is associated with increased mortality and a higher risk of graft rejection. It is likely that the development of a standard procedure for early identification of NOAF, as well as to develop recommendations for specific treatment targeted at avoiding the impacts of the illness, could provide a mortality reduction and provide an increased rate of successful LT
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