66 research outputs found

    Uji Daya Hambat Jamur Endofit Akar Bakau Achantus Terhadap Bakteri Staphylococcus Aureus Dan Escherichiae Coli

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    : Fungi and bacteria are microbes that are classified in the general stage of Endofit. Fungi is the most isolated form of Endofit. To this point studies articulating endofit are still at a scarce stage, without a doubt the corresponding relationship between plants and organisms. Endosimbions are considered in a state between grass that grows endemic in The United States of America (truf grass) and endofit fungi, Neotyphodium SP. The purpose of these researches are to see and understand the inhibition of bacteria growth from endofit fungi that can be obtained from the roots of Mangrove Acanthus against bacteria Staphylococcus Aureus and Escherichia coli. These studies have been researched since November 2013 to January 2014 at the Biomedical Research Laboratory Faculty of Medicine University of Sam Ratulangi. The research results that were conjured from the Mangrove root type Achantus have an inhibitory effect on the test bacteria research, which are Staphylococcus Aureus and Escherichia Coli

    MOESM1 of Well-to-wake analysis of ethanol-to-jet and sugar-to-jet pathways

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    Additional file 1. Additional file 1 includes a summary of key LUC-related emissions results from previous studies (Figure A1), the distribution function definition of 27 key parameters for the ETJ and STJ pathways (Table A1), and the sensitivity analysis results of key parameters for the ETJ and STJ pathways (Figures A2 to A4)

    Anaesthetic interventions for prevention of awareness during surgery

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    Background: General anaesthesia is usually associated with unconsciousness. 'Awareness' is when patients have postoperative recall of events or experiences during surgery. 'Wakefulness' is when patients become conscious during surgery, but have no postoperative recollection of the period of consciousness. Objectives: To evaluate the efficacy of two types of anaesthetic interventions in reducing clinically significant awareness: - anaesthetic drug regimens; and - intraoperative anaesthetic depth monitors. Search methods: We searched the Cochrane Central Register of Controlled Trials (CENTRAL, ISSUE 4 2016); PubMed from 1950 to April 2016; MEDLINE from 1950 to April 2016; and Embase from 1980 to April 2016. We contacted experts to identify additional studies. We performed a handsearch of the citations in the review. We did not search trial registries. Selection criteria: We included randomized controlled trials (RCTs) of either anaesthetic regimens or anaesthetic depth monitors. We excluded volunteer studies, studies of patients prior to skin incision, intensive care unit studies, and studies that only randomized different word presentations for memory tests (not anaesthetic interventions). Anaesthetic drug regimens included studies of induction or maintenance, or both. Anaesthetic depth monitors included the Bispectral Index monitor, M-Entropy, Narcotrend monitor, cerebral function monitor, cerebral state monitor, patient state index, and lower oesophageal contractility monitor. The use of anaesthetic depth monitors allows the titration of anaesthetic drugs to maintain unconsciousness. Data collection and analysis: At least two authors independently scanned abstracts, extracted data from the studies, and evaluated studies for risk of bias. We made attempts to contact all authors for additional clarification. We performed meta-analysis statistics in packages of the R language. Main results: We included 160 studies with 54,109 enrolled participants; 53,713 participants started the studies and 50,034 completed the studies or data analysis (or both). We could not use 115 RCTs in meta-analytic comparisons because they had zero awareness events. We did not merge 27 of the remaining 45 studies because they had excessive clinical and methodological heterogeneity. We pooled the remaining 18 eligible RCTs in meta-analysis. There are 10 studies awaiting classification which we will process when we update the review. The meta-analyses included 18 trials with 36,034 participants. In the analysis of anaesthetic depth monitoring (either Bispectral Index or M-entropy) versus standard clinical and electronic monitoring, there were nine trials with 34,744 participants. The overall event rate was 0.5%. The effect favoured neither anaesthetic depth monitoring nor standard clinical and electronic monitoring, with little precision in the odds ratio (OR) estimate (OR 0.98, 95% confidence interval (CI) 0.59 to 1.62). In a five-study subset of Bispectral Index monitoring versus standard clinical and electronic monitoring, with 34,181 participants, 503 participants gave awareness reports to a blinded, expert panel who adjudicated or judged the outcome for each patient after reviewing the questionnaires: no awareness, possible awareness, or definite awareness. Experts judged 351 patient awareness reports to have no awareness, 87 to have possible awareness, and 65 to have definite awareness. The effect size favoured neither Bispectral Index monitoring nor standard clinical and electronic monitoring, with little precision in the OR estimate for the combination of definite and possible awareness (OR 0.96, 95% CI 0.35 to 2.65). The effect size favoured Bispectral Index monitoring for definite awareness, but with little precision in the OR estimate (OR 0.60, 95% CI 0.13 to 2.75). We performed three smaller meta-analyses of anaesthetic drugs. There were nine studies with 1290 participants. Wakefulness was reduced by ketamine and etomidate compared to thiopental. Wakefulness was more frequent than awareness. Benzodiazepines reduces awareness compared to thiopental, ketamine, and placebo. Also, higher doses of inhaled anaesthetics versus lower doses reduced the risk of awareness. We graded the quality of the evidence as low or very low in the 'Summary of findings' tables for the five comparisons. Most of the secondary outcomes in this review were not reported in the included RCTs. Authors' conclusions: Anaesthetic depth monitors may have similar effects to standard clinical and electrical monitoring on the risk of awareness during surgery. In older studies comparing anaesthetics in a smaller portion of the patient sample, wakefulness occurred more frequently than awareness. Use of etomidate and ketamine lowered the risk of wakefulness compared to thiopental. Benzodiazepines compared to thiopental and ketamine, or higher doses of inhaled anaesthetics versus lower doses, reduced the risk of awareness

    Energy Efficiency and Greenhouse Gas Emission Intensity of Petroleum Products at U.S. Refineries

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    This paper describes the development of (1) a formula correlating the variation in overall refinery energy efficiency with crude quality, refinery complexity, and product slate; and (2) a methodology for calculating energy and greenhouse gas (GHG) emission intensities and processing fuel shares of major U.S. refinery products. Overall refinery energy efficiency is the ratio of the energy present in all product streams divided by the energy in all input streams. Using linear programming (LP) modeling of the various refinery processing units, we analyzed 43 refineries that process 70% of total crude input to U.S. refineries and cover the largest four Petroleum Administration for Defense District (PADD) regions (I, II, III, V). Based on the allocation of process energy among products at the process unit level, the weighted-average product-specific energy efficiencies (and ranges) are estimated to be 88.6% (86.2%–91.2%) for gasoline, 90.9% (84.8%–94.5%) for diesel, 95.3% (93.0%–97.5%) for jet fuel, 94.5% (91.6%–96.2%) for residual fuel oil (RFO), and 90.8% (88.0%–94.3%) for liquefied petroleum gas (LPG). The corresponding weighted-average, production GHG emission intensities (and ranges) (in grams of carbon dioxide-equivalent (CO<sub>2e</sub>) per megajoule (MJ)) are estimated to be 7.8 (6.2–9.8) for gasoline, 4.9 (2.7–9.9) for diesel, 2.3 (0.9–4.4) for jet fuel, 3.4 (1.5–6.9) for RFO, and 6.6 (4.3–9.2) for LPG. The findings of this study are key components of the life-cycle assessment of GHG emissions associated with various petroleum fuels; such assessment is the centerpiece of legislation developed and promulgated by government agencies in the United States and abroad to reduce GHG emissions and abate global warming

    U.S. Refinery Efficiency: Impacts Analysis and Implications for Fuel Carbon Policy Implementation

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    In the next two decades, the U.S. refining industry will face significant changes resulting from a rapidly evolving domestic petroleum energy landscape. The rapid influx of domestically sourced tight light oil and relative demand shifts for gasoline and diesel will impose challenges on the ability of the U.S. refining industry to satisfy both demand and quality requirements. This study uses results from Linear Programming (LP) modeling data to examine the potential impacts of these changes on refinery, process unit, and product-specific efficiencies, focusing on current baseline efficiency values across 43 existing large U.S. refineries that are operating today. These results suggest that refinery and product-specific efficiency values are sensitive to crude quality, seasonal and regional factors, and refinery configuration and complexity, which are determined by final fuel specification requirements. Additional processing of domestically sourced tight light oil could marginally increase refinery efficiency, but these benefits could be offset by crude rebalancing. The dynamic relationship between efficiency and key parameters such as crude API gravity, sulfur content, heavy products, residual upgrading, and complexity are key to understanding possible future changes in refinery efficiency. Relative to gasoline, the efficiency of diesel production is highly variable, and is influenced by the number and severity of units required to produce diesel. To respond to future demand requirements, refiners will need to reduce the gasoline/diesel (G/D) production ratio, which will likely result in greater volumes of diesel being produced through less efficient pathways resulting in reduced efficiency, particularly on the marginal barrel of diesel. This decline in diesel efficiency could be offset by blending of Gas to Liquids (GTL) diesel, which could allow refiners to uplift intermediate fuel streams into more efficient diesel production pathways, thereby allowing for the efficient production of incremental barrels of diesel without added capital investment for the refiner. Given the current wide range of refinery carbon intensity values of baseline transportation fuels in LCA models, this study has shown that the determination of refinery, unit, and product efficiency values requires careful consideration in the context of specific transportation fuel GHG policy objectives

    Life-Cycle Greenhouse Gas Emissions of Shale Gas, Natural Gas, Coal, and Petroleum

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    The technologies and practices that have enabled the recent boom in shale gas production have also brought attention to the environmental impacts of its use. It has been debated whether the fugitive methane emissions during natural gas production and transmission outweigh the lower carbon dioxide emissions during combustion when compared to coal and petroleum. Using the current state of knowledge of methane emissions from shale gas, conventional natural gas, coal, and petroleum, we estimated up-to-date life-cycle greenhouse gas emissions. In addition, we developed distribution functions for key parameters in each pathway to examine uncertainty and identify data gaps such as methane emissions from shale gas well completions and conventional natural gas liquid unloadings that need to be further addressed. Our base case results show that shale gas life-cycle emissions are 6% lower than conventional natural gas, 23% lower than gasoline, and 33% lower than coal. However, the range in values for shale and conventional gas overlap, so there is a statistical uncertainty whether shale gas emissions are indeed lower than conventional gas. Moreover, this life-cycle analysis, among other work in this area, provides insight on critical stages that the natural gas industry and government agencies can work together on to reduce the greenhouse gas footprint of natural gas

    Thiopental studies

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    A literature review of recently published papers using thiopental as part of the anesthetic technique

    Classification.Wang.Messina.Ward.grade

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    The classification system that tracks patients level of consciousness during anesthesia and surgery. Grades 0 to 5 were assigned to each of the 160 included RCTs
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