911 research outputs found
Ready or Not? Protecting the Public's Health in the Age of Bioterrorism, 2004
Examines ten key indicators to evaluate state preparedness to respond to bioterrorist attacks and other public health emergencies. Evaluates the federal government's role and performance, and offers recommendations for improving readiness
F as in Fat: How Obesity Policies Are Failing in America, 2005
Examines national and state obesity rates and government policies. Challenges the research community to focus on major research questions to inform policy decisions, and policymakers to pursue actions to combat the obesity crisis
F as in Fat: How Obesity Policies Are Failing in America, 2004
Examines national and state obesity rates and government policies. Focuses on setting a baseline of current policies and programs, and offers a comprehensive look at their range and quality
Testing the Hubble Law with the IRAS 1.2 Jy Redshift Survey
We test and reject the claim of Segal et al. (1993) that the correlation of
redshifts and flux densities in a complete sample of IRAS galaxies favors a
quadratic redshift-distance relation over the linear Hubble law. This is done,
in effect, by treating the entire galaxy luminosity function as derived from
the 60 micron 1.2 Jy IRAS redshift survey of Fisher et al. (1995) as a distance
indicator; equivalently, we compare the flux density distribution of galaxies
as a function of redshift with predictions under different redshift-distance
cosmologies, under the assumption of a universal luminosity function. This
method does not assume a uniform distribution of galaxies in space. We find
that this test has rather weak discriminatory power, as argued by Petrosian
(1993), and the differences between models are not as stark as one might expect
a priori. Even so, we find that the Hubble law is indeed more strongly
supported by the analysis than is the quadratic redshift-distance relation. We
identify a bias in the the Segal et al. determination of the luminosity
function, which could lead one to mistakenly favor the quadratic
redshift-distance law. We also present several complementary analyses of the
density field of the sample; the galaxy density field is found to be close to
homogeneous on large scales if the Hubble law is assumed, while this is not the
case with the quadratic redshift-distance relation.Comment: 27 pages Latex (w/figures), ApJ, in press. Uses AAS macros,
postscript also available at
http://www.astro.princeton.edu/~library/preprints/pop682.ps.g
Protected gates for topological quantum field theories
We study restrictions on locality-preserving unitary logical gates for
topological quantum codes in two spatial dimensions. A locality-preserving
operation is one which maps local operators to local operators --- for example,
a constant-depth quantum circuit of geometrically local gates, or evolution for
a constant time governed by a geometrically-local bounded-strength Hamiltonian.
Locality-preserving logical gates of topological codes are intrinsically fault
tolerant because spatially localized errors remain localized, and hence
sufficiently dilute errors remain correctable. By invoking general properties
of two-dimensional topological field theories, we find that the
locality-preserving logical gates are severely limited for codes which admit
non-abelian anyons; in particular, there are no locality-preserving logical
gates on the torus or the sphere with M punctures if the braiding of anyons is
computationally universal. Furthermore, for Ising anyons on the M-punctured
sphere, locality-preserving gates must be elements of the logical Pauli group.
We derive these results by relating logical gates of a topological code to
automorphisms of the Verlinde algebra of the corresponding anyon model, and by
requiring the logical gates to be compatible with basis changes in the logical
Hilbert space arising from local F-moves and the mapping class group.Comment: 50 pages, many figures, v3: updated to match published versio
Genomic Education – Bench to Bedside: A Novel Approach to Teaching Genetic Diagnosis
Problem: Teaching genetic diagnosis is required in all medical schools and physician assistant programs. However, with thousands of relevant findings and thousands more rare diseases, lectures and narrative resources are inadequate for the task. Whatever information that is taught is easily forgotten and does not carry over into the clinic. Many rare disease patients suffer through “diagnostic odysseys” (3 to 30 years to correct diagnosis). Approach: We used a commercially available diagnostic decision support system (DDSS) that encompasses all Mendelian disorders with known genes, together with other conditions in their differential diagnosis, and a case-based educational approach to teach diagnostic skills in a way that could then be replicated in the clinic. After a lecture, which included a demonstration using the DDSS with a sample case, 74 students were assigned to replicate the sample case at home and then complete 7 other anonymized cases, all with known rare diagnoses. After each case, students saved the “patient summary” that included the findings entered and differential diagnosis list and submitted it as homework. Students also completed a questionnaire about their experience, including satisfaction. Outcomes: Students were effective at diagnosing rare diseases in 483 of the 514 testing instances, a 94% success rate, with success defined as the correct diagnosis being listed in the differential diagnosis. Eighty-five percent of students rated this interactive learning session “highly,” encouraged us to repeat the assignment next year, and 89% reported that they wanted to use the DDSS during their clinical rotations in the coming year. Next Steps: We plan to refine the cases, add more material on findings, and ensure that all the synonyms students might use are in the software tool. We plan to repeat the program next year and recommend its use more widely in medical education
Ready or Not? Protecting the Public's Health in the Age of Bioterrorism, 2005
Examines ten key indicators to evaluate state preparedness to respond to bioterrorist attacks and other public health emergencies. Evaluates the federal government's role and performance, and offers recommendations for improving readiness
Type I D-branes in an H-flux and twisted KO-theory
Witten has argued that charges of Type I D-branes in the presence of an
H-flux, take values in twisted KO-theory. We begin with the study of real
bundle gerbes and their holonomy. We then introduce the notion of real bundle
gerbe KO-theory which we establish is a geometric realization of twisted
KO-theory. We examine the relation with twisted K-theory, the Chern character
and provide some examples. We conclude with some open problems.Comment: 23 pages, Latex2e, 2 new references adde
Locating Battery Charging Stations to Facilitate Almost Shortest Paths
We study a facility location problem motivated by requirements pertaining to the distribution of charging stations for electric vehicles: Place a minimum number of battery charging stations at a subset of nodes of a network, so that battery-powered electric vehicles will be able to move between destinations using "t-spanning" routes, of lengths within a factor t > 1 of the length of a shortest path, while having sufficient charging stations along the way. We give constant-factor approximation algorithms for minimizing the number of charging stations, subject to the t-spanning constraint. We study two versions of the problem, one in which the stations are required to support a single ride (to a single destination), and one in which the stations are to support multiple rides through a sequence of destinations, where the destinations are revealed one at a time
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