40 research outputs found

    Qualitätsmanagement Lehrveranstaltungen : Empfehlungen für Konzipierung, Etablierung, Durchführung und Verwendung von Evaluationen

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    Um institutionell akkreditiert zu werden, müssen Hochschulen in der Schweiz die Qualitätsstandards für die institutionelle Akkreditierung der Richtlinien des Hochschulrates für die Akkreditierung im Hochschulbereich (Akkreditierungsrichtlinien HFKG, 2015) erfüllen. Mit der institutionellen Akkreditierung sind insbesondere das Bezeichnungsrecht „Universität“, „Fachhochschule“ oder „Pädagogische Hochschule“ und die Gewährung von Bundesbeiträgen verbunden. Die Qualitätsstandards für die institutionelle Akkreditierung sind auf einem relativ hohen Abstraktionsniveau formuliert, um einen Rahmen für das Qualitätsmanagement verschiedener Hochschulen und Hochschuleinheiten sowie Hochschultätigkeiten mit ihren charakteristischen Merkmalen und Bedingungen bieten zu können. Zweck dieses Dokuments ist es, die Qualitätsstandards für die institutionelle Akkreditierung auf das Qualitätsmanagement von Lehrveranstaltungen auszuführen. Zudem werden die Qualitätsstandards um die Evaluationsstandards der Schweizerischen Evaluationsgesellschaft (SEVAL, 2016) ergänzt. Die Evaluationsstandards bieten eine Grundlage und Hilfestellung für die Planung und Durchführung von professionellen Evaluationen

    The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

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    Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age  6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score  652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701

    Piroxicam-Induced Renal Failure and Hyperkalemia

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    Phase image characterization of localized and generalized left ventricular contraction abnormalities

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    To evaluate their phase image characteristics, 61 patients with varying left ventricular contraction abnormalities were studied. In 16 normal patients, the left ventricular phase image revealed a homogeneous pattern, a narrow bell-shaped histogram and an orderly spatial progression of phase angle (φ¯). In 16 patients with segmental abnormalities, the left ventricular phase image showed a region of uniformly delayed phase angle corresponding to the site of segmental abnormality, a discrete secondary histogram peak and a discontinuous, but orderly, spatial progression of phase angle. The mean phase angle (φ¯)(23.6 ± 15.7°) and its standard deviation (17.6 ± 7.2°) differed from the normal group (7.6 ± 11.1°, p < 0.002 and 8.9 ± 2.8°, p < 0.001). The percent of end-diastolic volume involved in the segmental abnormality, calculated using phase data in 13 of these and in 11 additional patients with a left ventricular aneurysm on ventriculography, correlated well with the percent akinetic segment on scintigraphic (r = 0.78) and angiographic (r = 0.84) study.In 18 patients with generalized abnormalities, the left ventricular phase image revealed multiple regions of inhomogeneous phase angle, a grossly irregular histogram and a disorderly spatial progression of phase angle. The mean phase angle (56.4 ± 23.9°) and standard deviation (27.3 ± 7.1°) differed from values in the normal group and from patients with segmental contraction abnormalities (both p < 0.001). The mean phase angle and its standard deviation in scattered regions with abnormally prolonged phase angle differed significantly from abnormal regions in patients with segmental abnormalities (both p < 0.001).These patterns of left ventricular phase angle demonstrate characteristics that may help differentiate between ventricles with segmental and generalized contraction abnormalities. Their relation to underlying pathophysiology and potential clinical implications should be considered

    Qualitätsmanagement Lehrveranstaltungen : Empfehlungen für Konzipierung, Etablierung, Durchführung und Verwendung von Evaluationen

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    Um institutionell akkreditiert zu werden, müssen Hochschulen in der Schweiz die Qualitätsstandards für die institutionelle Akkreditierung der Richtlinien des Hochschulrates für die Akkreditierung im Hochschulbereich (Akkreditierungsrichtlinien HFKG, 2015) erfüllen. Mit der institutionellen Akkreditierung sind insbesondere das Bezeichnungsrecht „Universität“, „Fachhochschule“ oder „Pädagogische Hochschule“ und die Gewährung von Bundesbeiträgen verbunden. Die Qualitätsstandards für die institutionelle Akkreditierung sind auf einem relativ hohen Abstraktionsniveau formuliert, um einen Rahmen für das Qualitätsmanagement verschiedener Hochschulen und Hochschuleinheiten sowie Hochschultätigkeiten mit ihren charakteristischen Merkmalen und Bedingungen bieten zu können. Zweck dieses Dokuments ist es, die Qualitätsstandards für die institutionelle Akkreditierung auf das Qualitätsmanagement von Lehrveranstaltungen auszuführen. Zudem werden die Qualitätsstandards um die Evaluationsstandards der Schweizerischen Evaluationsgesellschaft (SEVAL, 2016) ergänzt. Die Evaluationsstandards bieten eine Grundlage und Hilfestellung für die Planung und Durchführung von professionellen Evaluationen

    Phase image evaluation of patients with ventricular pre-excitation syndromes

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    To localize bypass pathways, left and right ventricular regions were analyzed at rest by phase image analysis in 18 patients with ventricular pre-excitation syndromes. These were compared with image findings in 18 normal subjects. In each of 17 patients with pre-excitation, the site localized on electrophysiologic study correlated closely with the region of earliest ventricular phase angle. This site could be objectively separated from that in normal subjects in each of eight patients with an active left-sided pathway and in both patients with a right-sided pathway. Those with a septal pathway revealed earliest septal phase angle, but could not be separated from normal subjects. In the eight patients with an active left bypass tract, the onset, upstroke and peak of the left ventricular phase histogram preceded those of the right ventricular histogram. Those with a left-sided pathway demonstrated a mean left ventricular phase angle, a difference between mean left and mean right ventricular phase angle and a difference between earliest left and right ventricular phase angles which was significantly less than that in normal subjects (p < 0.05). These variables presented characteristic converse changes in those with a right-sided pathway.Sequential phase changes in 10 studies suggested “fusion” of normal septal with lateral bypass fronts. Electrocardiographic and electrophysiologic localization of the bypass pathway agreed in only 8 of 14 patients with a recognized delta wave.The phase image represents a new, noninvasive method of evaluating ventricular pre-excitation. The method may provide useful information complementary to that of electrocardiographic and electrophysiologic analysis

    Qualitätsmanagement Lehrveranstaltungen: Empfehlungen für Konzipierung, Etablierung, Durchführung und Verwendung von Evaluationen.

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    Um institutionell akkreditiert zu werden, müssen Hochschulen in der Schweiz die Qualitätsstan-dards für die institutionelle Akkreditierung der Richtlinien des Hochschulrates für die Akkreditierung im Hochschulbereich (Akkreditierungsrichtlinien HFKG, 2015) erfüllen. Mit der institutionellen Akkreditierung sind insbesondere das Bezeichnungsrecht „Universität“, „Fachhochschule“ oder „Pädagogische Hochschule“ und die Gewährung von Bundesbeiträgen verbunden. Die Qualitätsstandards für die institutionelle Akkreditierung sind auf einem relativ hohen Abstraktionsniveau formuliert, um einen Rahmen für das Qualitätsmanagement verschiedener Hochschulen und Hochschuleinheiten sowie Hochschultätigkeiten mit ihren charakteristischen Merkmalen und Bedingungen bieten zu können. Zweck dieses Dokuments ist es, die Qualitätsstandards für die institutionelle Akkreditierung auf das Qualitätsmanagement von Lehrveranstaltungen auszuführen. Zudem werden die Qualitätsstandards um die Evaluationsstandards der Schweizerischen Evaluationsgesell-schaft (SEVAL, 2016) ergänzt. Die Evaluationsstandards bieten eine Grundlage und Hilfestellung für die Planung und Durchführung von professionellen Evaluationen.+ ID der Publikation: hslu_57909 + Art des Beitrages: Leitfaden + Sprache: Deutsch + Letzte Aktualisierung: 2019-02-04 10:24:5

    Assessment of pericardial constraint: The relation between right ventricular filling pressure and pericardial pressure measured after pericardiocentesis

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    Experimental studies have shown that right ventricular filling pressure (that is, intracavitary diastolic pressure) approximates pericardial surface pressure but, in many patients after removal of pericardial effusion, right ventricular filling pressure has been found to markedly exceed pericardial pressure recorded by an open catheter. The aim of this study was to determine whether this apparent contradiction was related to the technique of pericardial pressure measurement. Nine patients with chronic pericardial effusion were studied and, although these pressures diverged to varying degrees in individual patients, the previous observation was confirmed in that, although initially similar, right ventricular filling pressure and pericardial pressure (measured by means of an open catheter) tended to diverge during removal of the effusate; when the evacuation was as complete as possible pericardial pressure was 2.1 ± 1.0 (mean ± SE), while right ventricular filling pressure was 8.7 ± 1.7 mm Hg (p < 0.01).In six open chest, anesthetized, volume-loaded dogs with pericardial effusion (50 ml), right ventricular filling pressure and pericardial pressures measured with both open catheter and flat balloon were all equal. With decreasing volume of pericardial fluid, right ventricular filling pressure and pericardial pressure (by catheter) diverged as had been observed in patients. However, pericardial pressure (balloon) continued to be equal to right ventricular filling pressure. (With 0 ml in the pericardium, right ventricular filling pressure = 12.9 ± 0.9 mm Hg, pericardial pressure [catheter] = 1.4 ± 1.9 mm Hg and pericardial pressure [balloon] = 12.4 ± 1.5 mm Hg.) Thus, these observations support the use of right ventricular filling pressure as an estimate of pericardial constraint in patients
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