Collective dynamics and pair-distribution function of active Brownian ellipsoids

While the collective dynamics of spherical active Brownian particles is relatively well understood by now, the much more complex dynamics of nonspherical active particles still raises interesting open questions. Previous work has shown that the dynamics of rod-like or ellipsoidal active particles can differ significantly from that of spherical ones. Here, we obtain the full state diagram of active Brownian ellipsoids depending on the P\'eclet number and packing density via computer simulations. The system is found to exhibit a rich state behavior that includes cluster formation, local polar order, polar flocks, and disordered states. Moreover, we obtain numerical results and an analytical representation for the pair-distribution function of active ellipsoids. This function provides useful quantitative insights into the collective behavior of active particles with lower symmetry and has potential applications in the development of predictive theoretical models.Comment: 30 pages, 8 figures, 14 table

Detection of Amblyomma mixtum (Acari: Ixodidae) in Germany on a Human Traveler Returning from Cuba

The importation of exotic ticks to Germany on infested humans is rarely reported. Here we describe the detection of an Amblyomma mixtum nymph harboring Rickettsia amblyommatis by a tourist returning from a holiday trip to Cuba. Tick infestation may be neglected by tourists. Therefore, careful anamnesis and diagnosis should be carried out when tourists return from tropical and subtropical countries suffering from nonspecific symptoms, such as fever and malaise.Fil: Chitimia Dobler, Lidia. Bundeswehr Institute Of Microbiology; Alemania. Universidad de Hohenheim; AlemaniaFil: Schaper, Sabine. Bundeswehr Institute Of Microbiology; AlemaniaFil: Mansfeld, Peter. Museum of Natural History, Kassel; AlemaniaFil: Gonschorrek, Joachim. No especifíca;Fil: Bröker, Michael. No especifíca;Fil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Santa Fe. Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentin

Hepatocellular adenoma: When and how to treat? Update of current evidence

Hepatocellular adenoma (HCA) is a rare, benign liver tumor. Discovery of this tumor is usually as an incidental finding, correlated with the use of oral contraceptives, or pregnancy. Treatment options have focused on conservative management for the straightforward, smaller lesions (5 cm) that pose a greater risk of hemorrhage or malignant progression. In recent years, a new molecular subclassification of HCA has been proposed, associated with characteristic morphological features and loss or increased expression of immunohistochemical markers. This subclassification could possibly provide considerable benefits in terms of patient stratification, and the selection of treatment options. In this review we discuss the decision-making processes and associated risk analyses that should be made based on lesion size, and subtype. The usefulness of this subclassification system in terms of the procedures instigated as part of the diagnostic work-up of a suspected HCA will be outlined, and suitable treatment schemes proposed

Analysis of Bonding between Conjugated Organic Molecules and Noble Metal Surfaces Using Orbital Overlap Populations

The electronic structure of metal−organic interfaces is of paramount importance for the properties of organic electronic and single-molecule devices. Here, we use so-called orbital overlap populations derived from slab-type band-structure calculations to analyze the covalent contribution to the bonding between an adsorbate layer and a metal. Using two prototypical molecules, the strong acceptor 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane (F4TCNQ) on Ag(111) and the strong donor 1H,1′H-[4,4′]bipyridinylidene (HV0) on Au(111), we present overlap populations as particularly versatile tools for describing the metal−organic interaction. Going beyond traditional approaches, in which overlap populations are represented in an atomic orbital basis, we also explore the use of a molecular orbital basis to gain significant additional insight. On the basis of the derived quantities, it is possible to identify the parts of the molecules responsible for the bonding and to analyze which of the molecular orbitals and metal bands most strongly contribute to the interaction and where on the energy scale they interact in bonding or antibonding fashion

Semiclassical spectra of gauge fields

We study the asymptotic behavior of the eigenvalues of the Schrodinger operator with a vector potential on a compact manifold, as Planck's constant tends to zero. We obtain estimates in terms of periodic trajectories of Wong's flow which are uniform in the "charge" parameter.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/30254/1/0000649.pd

Representing absence of evidence: why algorithms and representations matter in models of language and cognition

Theories of language and cognition develop iteratively from ideas, experiments and models. The abstract nature of “cognitive processes” means that computational models play a critical role in this, yet bridging the gaps between models, data, and interpretations is challenging. While the how and why computations are performed is often the primary research focus, the conclusions drawn from models can be compromised by the representations chosen for them. To illustrate this point, we revisit a set of empirical studies of language acquisition that appear to support different models of learning from implicit negative evidence. We examine the degree to which these conclusions were influenced by the representations chosen and show how a plausible single mechanism account of the data can be formulated for representations that faithfully capture the task design. The need for input representations to be incorporated into model conceptualisations, evaluations, and comparisons is discussed

Defined monoclonal antibodies to Escherichia coli β-galactosidase as a tool for characterisation of recombinant expression products

AbstractMouse monoclonal antibodies were prepared against β-galactosidase (EC 3.2.1.23) of Escherichia coli. The binding sites of these monoclonal antibodies within the β-galactosidase molecule were estimated by immunoblot analyses to various defined peptide regions of β-galactosidase, encoded by expression plasmids. Monoclonal antibodies, were characterised, which either bind to the amino-terminal or to the carboxy-terminal region or to an internal section of β-galactosidase. These defined monoclonal antibodies were shown to be a useful tool for characterisation of β-galactosidase fusion proteins expressed in Escherichia coli.Galactosidase, β-; Monoclonal antibody; Recombinant expression product; Epitope mapping; (E. coli

Expression of human antithrombin III in Saccharomyces cerevisiae and Schizosaccharomyces pombe

Bröker M, Ragg H, Karges HE. Expression of human antithrombin III in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Biochim. Biophys. Acta. 1987;908:203-213

abp.ellipsoidal2d.pairdistribution

<p>Python module that provides a function for the full pair-distribution function for a homogeneous suspension of ellipsoidal active Brownian particles interacting by a Gay-Berne potential in two spatial dimensions.</p>R.W. is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – 283183152 (WI 4170/3)