743 research outputs found

    Discovering the Perceptions of Pre-Service/Novice Elementary Educators Toward Health Education and Health Instruction in the Elementary Classroom

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    Objectives: The impact of unhealthy choices on Americans is no longer an adult\u27s only issue. Health disparities previously affecting adults are appearing at ever-increasing rates in children. A strategy to address this examines the likelihood that elementary teachers act as healthy role models while providing quality health instruction. Therefore, the purpose of this study was to assess the effect of the preservice elementary teacher training experience on the potential delivery of elementary classroom health instruction by clarifying the impact of programmatic training influences on the attitudes and behavioral intent of preservice elementary educators to teach health.;Methods: A sample of 157 candidates were selected for this study consisting of preservice (in their final semester) and novice elementary educators (within 3 years from graduation) from an accredited teacher training program in WV. Participants responded to an anonymous, electronic survey containing demographic and attitudinal questions focused on health education experiences during and after their undergraduate, teacher training experience. Frequencies and analyses of variance were used to examine responses and compare survey items.;Results: 93 participants responded to the 38-item questionnaire. 23 items assessed the three levels of behavioral intent: attitude (A), subjective norms (SN), and perceived behavioral control (PBC). Findings indicated that attitude was most affected by health education teacher training (p≤ .003), whether or not respondents recalled specific training (three or more curricular components (p≤ .042), one or two (p≤ .0074), or none at all (p≤ .004)). Correlations were found between measures of personal health and Attitude (health status: p≤ .034; exercise frequency: p≤ .044) and Subjective Norms (health status: p≤ .025; exercise frequency: p≤ -.005). As recall of training on specific curricular components increased, the discipline of Health increased in importance when compared to math, science, technology and reading/language arts (no recall = 4.17, recall of one or two =3.85, recall of three or more = 3.48).;Conclusions: Required training profoundly affected attitudes toward health education. There was a significant relationship between attitude and measures of personal health. Powerful others (SN) played an impressive role in influencing perceptions of value regarding the discipline of Health Education. No particular group of course components influenced behavioral intent and attitude as much as the completion of a training program requirement on specific/organized curricula in health education. Training improved Health Education\u27s academic ranking

    Understanding your water test report (1995)

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    "New 7/93, Reprinted 4/95/5M.""Water Quality.""Focus area : drinking water.""Published by University Extension. University of Missouri-Columbia.""Reviewed and adapted for Missouri by Wanda Eubank, Jerry Carpenter, Bev Maltsberger, University of Missouri-Columbia, and Nix Anderson, Missouri Department of Health, from Understanding Your Water Test Report by Michael H. Bradshaw, Health and Safety Extension Specialist and G. Morgan Powell, Natural Resource Engineer, Kansas State University.

    Chandra Observations of the Interacting NGC 4410 Galaxy Group

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    We present high resolution X-ray imaging data from the ACIS-S instrument on the Chandra telescope of the nearby interacting galaxy group NGC 4410. Four galaxies in the inner portion of this group are clearly detected by Chandra, including the peculiar low luminosity radio galaxy NGC 4410A. In addition to a nuclear point source, NGC 4410A contains diffuse X-ray emission, including an X-ray ridge extending out to about 12" (6 kpc) to the northwest of the nucleus. This ridge is coincident with an arc of optical emission-line gas, which has previously been shown to have optical line ratios consistent with shock ionization. This structure may be due to an expanding superbubble of hot gas caused by supernovae and stellar winds or by the active nucleus. The Chandra observations also show four or five possible compact ultra-luminous X-ray (ULX) sources (L(x) >= 10^39 erg/s) associated with NGC 4410A. At least one of these candidate ULXs appears to have a radio counterpart, suggesting that it may be due to an X-ray binary with a stellar-mass black hole, rather than an intermediate mass black hole. In addition, a faint diffuse intragroup X-ray component has been detected between the galaxies (L(x) ~ 10^41 erg/s). This supports the hypothesis that the NGC 4410 group is in the process of evolving via mergers from a spiral-dominated group (which typically have no X-ray-emitting intragroup gas) to an elliptical-dominated group (which often have a substantial intragroup medium).Comment: 27 pages, 14 figures; Accepted by Astronomical Journal; color images at http://www.etsu.edu/physics/bsmith/research/n4410.htm

    HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney

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    HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney. Studies assessing mechanisms of proximal tubular cell (PTC) physiology and pathophysiology increasingly utilize cell culture systems to avoid the complexity of whole organ/whole animal experiments. However, no well-differentiated PTC line derived from adult human kidney currently exists. Therefore, the goal of this research was to establish such a line by transduction with human papilloma virus (HPV 16) E6/E7 genes. A primary PTC culture from normal adult human renal cortex was exposed to a recombinant retrovirus containing the HPV 16 E6/E7 genes, resulting in a cell line designated HK-2 (human kidney-2) which has grown continuously in serum free media for more than one year. HK-2 cell growth is epidermal growth factor dependent and the cells retain a phenotype indicative of well-differentiated PTCs (positive for alkaline phosphatase, gamma glutamyltranspeptidase, leucine aminopeptidase, acid phosphatase, cytokeratin, α3β1 integrin, fibronectin; negative for factor VHI-related antigen, 6.19 antigen and CALLA endopeptidase). Furthermore, HK-2 cells retain functional characteristics of proximal tubular epithelium (Na+ dependent/phlorizin sensitive sugar transport; adenylate cyclase responsiveness to parathyroid, but not to antidiuretic, hormone). The E6/E7 genes are present in the HK-2 genome, as determined by PCR. To assess its potential usefulness as a tool for studying injury and repair, HK-2 cells were exposed to a toxic concentration of H2O2 ± iron chelation (deferoxamine) or hydroxyl radical scavenger (Na benzoate) therapy. Only the former blocked H2O2 cytotoxicity, reproducing results previously obtained with freshly isolated rat proximal tubular segments. In conclusion, an immortalized adult human PTC line has been established by transduction with HPV 16 E6/E7 genes. It appears to be well-differentiated on the basis of its histochemical, immune cytochemical, and functional characteristics, and it can reproduce experimental results obtained with freshly isolated PTCs. Thus, this new PTC line could have substantial research application

    Sodium oxybate therapy provides multidimensional improvement in fibromyalgia: results of an international phase 3 trial

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    Background: Fibromyalgia is characterised by chronic musculoskeletal pain and multiple symptoms including fatigue, multidimensional function impairment, sleep disturbance and tenderness. Along with pain and fatigue, non-restorative sleep is a core symptom of fibromyalgia. Sodium oxybate (SXB) is thought to reduce non-restorative sleep abnormalities. This study evaluated effects of SXB on fibromyalgia-related pain and other symptoms. Methods: 573 patients with fibromyalgia according to 1990 American College of Rheumatology criteria were enrolled at 108 centres in eight countries. Subjects were randomly assigned to placebo, SXB 4.5 g/night or SXB 6 g/night. The primary efficacy endpoint was the proportion of subjects with ≥30% reduction in pain visual analogue scale from baseline to treatment end. Other efficacy assessments included function, sleep quality, effect of sleep on function, fatigue, tenderness, health-related quality of life and subject's impression of change in overall wellbeing. Results: Significant improvements in pain, sleep and other symptoms associated with fibromyalgia were seen in SXB treated subjects compared with placebo. The proportion of subjects with ≥30% pain reduction was 42.0% for SXB4.5 g/night (p=0.002) and 51.4% for SXB6 g/night (p<0.001) versus 26.8% for placebo. Quality of sleep (Jenkins sleep scale) improved by 20% for SXB4.5 g/night (p≤0.001) and 25% for SXB6 g/night (p≤0.001) versus 0.5% for placebo. Adverse events with an incidence ≥5% and twice placebo were nausea, dizziness, vomiting, insomnia, anxiety, somnolence, fatigue, muscle spasms and peripheral oedema. Conclusion: These results, combined with findings from previous phase 2 and 3 studies, provide supportive evidence that SXB therapy affordsimportant benefits across multiple symptoms in subjects with fibromyalgia

    The Role Modelling and Farming Systems Research Can Play in Redesigning Grazing Systems for Improved Productivity and Environmental Sustainability

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    Achieving production and natural resource outcomes from farming systems is critical with growing demand for livestock products, increasing pressure on land and water resources and the desire of farmers to improve profit and standard of living. In many countries this brings to the fore a number of policy dilemmas and conflicts in terms of pastoral household livelihood, regional economic growth and development, as well as natural resource management. By using two case studies; (1) Temperate Grasslands in Southern Australia (EverGraze project); and (2) Western Grasslands in North West China (ACIAR project), this paper considers how farming systems can be redesigned for production and environmental outcomes using modelling and farming systems research. Farming systems, as well as the regions and economies in which they operate, are complex and under constant change. The use of models combined with good science, relevant data and regional validation is essential to examine alternative systems that are better suited to changed operating conditions. Bio-economic modelling helps to understand trade-offs between production and enterprise performance and environmental sustainability over time and, most importantly, where multiple benefits from farming systems are possible. We contend that it is possible to redesign farming systems with both enterprise and environmental sustainability in mind. However the approach used to design and test alternative farming systems is important in an era of declining research resources and increasing complexity

    Antenatal steroid exposure and heart rate variability in adolescents born with very low birth weight

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    Reduced heart rate variability (HRV) suggests autonomic imbalance in the control of heart rate and is associated with unfavorable cardiometabolic outcomes. We examined whether antenatal corticosteroid (ANCS) exposure had long-term programming effects on heart rate variability (HRV) in adolescents born with very low birth weight (VLBW)

    Low-Resolution Imaging Spectrometer for the Keck Telescope

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    The Low Resolution Imaging Spectrometer is designed for use at the Cassegrain focus of the Keck 10-m telescope. It provides the capability of acquiring low resolution (R equals 1000 to 5000) digital spectra, as well as 6 X 8 arc-minute moderately high spatial resolution (4.65 pixels/arc-second) direct images. Spectroscopy can be carried out with single slits which are 3 arc-minutes long. In addition punched multi-slits can also be employed which allow for the acquisition of at least forty spectra simultaneously. Since the instrument is designed to be as efficient as possible, it is a double spectrograph, with a dichroic splitting the blue and red light into separate optical paths after the collimator. Only the red side has been constructed thus far. With a 2048 by 2048 thinned Tektronix CCD as the detector the total efficiency of the red side at the peak of the grating blaze is predicted to be nearly 40%. Results of the commissioning observing runs will be described

    A dynamic database of microarray-characterized cell lines with various cytogenetic and genomic backgrounds

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    The Human Genetic Cell Repository sponsored by the National Institute of General Medical Sciences (NIGMS) contains more than 11,000 cell lines and DNA samples collected from numerous individuals. All of these cell lines and DNA samples are categorized into several collections representing a variety of disease states, chromosomal abnormalities, heritable diseases, distinct human populations, and apparently healthy individuals. Many of these cell lines have previously been studied with detailed conventional cytogenetic analyses, including G-banded karyotyping and fluorescence in situ hybridization. This work was conducted by investigators at submitting institutions and scientists at Coriell Institute for Medical Research, where the NIGMS Repository is hosted. Recently, approximately 900 cell lines, mostly chosen from the Chromosomal Aberrations and Heritable Diseases collections, have been further characterized in detail at the Coriell Institute using the Affymetrix Genome-Wide Human SNP Array 6.0 to detect copy number variations and copy number neutral loss of heterozygosity. A database containing detailed cytogenetic and genomic information for these cell lines has been constructed and is freely available through several sources, such as the NIGMS Repository website and the University of California at Santa Cruz Genome Browser. As additional cell lines are analyzed and subsequently added into it, the database will be maintained dynamically
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