A proof-of-concept 5G mobile gateway with eBPF

In this poster we propose the first proof-of-concept open-source implementation of a 5G Mobile Gateway based on eBPF/XDP and present benchmarks that compare its performance with alternative technologies. We show how it outperforms other in-kernel solutions (e.g., OvS) and is comparable with DPDK-based platforms

Providing Telco-oriented Network Services with eBPF: The Case for a 5G Mobile Gateway

Although several technologies exist for high-speed data plane processing, such as DPDK, the above technologies require a rigid partitioning of the resources of the system, such as dedicated CPU cores and network interfaces. Unfortunately, this is not always possible when running at the edge of the network, in which a few servers are available in each cluster and a mixture of data and control plane services must coexist on the same hardware. In this respect, eBPF can become a better alternative thanks to its integration in the vanilla Linux kernel, which enables contemporary support for data and control plane services, hence enabling a more efficient usage of the (scarce) computing resources. This paper proposes the first proof-of-concept open-source implementation of a 5G Mobile Gateway based on eBPF/XDP, highlighting the possible challenges (e.g., to create traffic policers, as buffering is not available in eBPF) and the resulting architecture. The result is characterized in terms of performance and scalability and compared with alternative technologies, showing that it outperforms other in-kernel solutions (e.g., Open vSwitch) and is comparable with DPDK-based platforms

Comorbid depressive disorders in ADHD. the role of ADHD severity, subtypes and familial psychiatric disorders

ObjectiveaaTo evaluate the presence of Major Depressive Disorder (MDD) and Dysthymic Disorder (DD) in a sample of Italian children with Attention Deficit Hyperactivity Disorder (ADHD) and to explore specific features of comorbid depressive disorders in ADHD. MethodsaaThree hundred and sixty-six consecutive, drug-naïve Caucasian Italian outpatients with ADHD were recruited and comorbid disorders were evaluated using DSM-IV-TR criteria. To evaluate ADHD severity, parents of all children filled out the ADHD Rating Scale. Thirty-seven children with comorbid MDD or DD were compared with 118 children with comorbid conduct disorder and 122 without comorbidity for age, sex, IQ level, family psychiatric history, and ADHD subtypes and severity. Resultsaa42 of the ADHD children displayed comorbid depressive disorders: 16 exhibited MDD, 21 DD, and 5 both MDD and DD. The frequency of hyperactive-impulsive subtypes was significantly lower in ADHD children with depressive disorders, than in those without any comorbidity. ADHD children with depressive disorders showed a higher number of familial psychiatric disorders and higher score in the Inattentive scale of the ADHD Rating Scale, than children without any comorbidity. No differences were found for age, sex and IQ level between the three groups. Conclusions: Consistent with previous studies in other countries, depressive disorders affect a significant proportion of ADHD children in Italy. Patient assessment and subsequent treatment should take into consideration the possible presence of this comorbidity, which could specifically increase the severity of ADHD attention problems

Performance Comparison of Technological Solutions for Spark Applications in AWS

Cloud computing is providing a pay-as-you-go in-frastructure for the deployment of complex applications, with auto-scaling support and the ability to manage and process huge amount of data. However, due to the underlying complexity of the cloud infrastructure, it is not trivial to evaluate the setup providing the best performance of such scenario. To this aim the present paper proposes a thorough performance evaluation of a real application in a Cloud platform, measuring the impact of several design choices and technological solution. The experimental results, based on a real application and on realistic data can provide a significant insight that can integrate the traditional approach of cloud performance evaluation based on synthetic benchmarks

Lagrangian Variational Framework for Boundary Value Problems

A boundary value problem is commonly associated with constraints imposed on a system at its boundary. We advance here an alternative point of view treating the system as interacting "boundary" and "interior" subsystems. This view is implemented through a Lagrangian framework that allows to account for (i) a variety of forces including dissipative acting at the boundary; (ii) a multitude of features of interactions between the boundary and the interior fields when the boundary fields may differ from the boundary limit of the interior fields; (iii) detailed pictures of the energy distribution and its flow; (iv) linear and nonlinear effects. We provide a number of elucidating examples of the structured boundary and its interactions with the system interior. We also show that the proposed approach covers the well known boundary value problems.Comment: 41 pages, 3 figure

Constitutional trisomy 8 as first mutation in multistep carcinogenesis: clinical, cytogenetic, and molecular data on three cases.

Three patients, with constitutional trisomy 8 mosaicism (CT8M), who developed a malignancy are reported. The diagnoses were refractory anaemia, acute lymphoblastic leukaemia, and idiopathic myelofibrosis. In the child with acute leukaemia, the CT8M was diagnosed at birth due to severe dysmorphisms and malformations; the other two patients showed a milder phenotype, and the CT8M was diagnosed only after the finding of trisomy 8 in neoplastic cells. The review of eight similar, previously reported cases and the clinical, cytogenetic, and molecular studies performed in our patients led us to make the following observations: (1) CT8M predisposes to neoplasms, preferentially to myelo- or lymphoproliferative diseases; (2) a gene dosage effect for glutathione reductase in red blood cells was seen in two of our patients; (3) the wide phenotypic variation of CT8M was confirmed: trisomy 8 in neoplastic cells of phenotypically near-normal cases may be misinterpreted as acquired; and (4) molecular studies suggested a postzygotic origin of the trisomy in our three cases, with the supernumerary chromosome being of paternal origin in one case and of maternal origin in the other two. We postulate that the trisomy 8 in neoplasms may often occur by mitotic nondisjunction in an early embryonic multipotent cell and that what is usually interpreted as an acquired trisomy 8 may in fact be CT8M. The constitutional trisomy 8 would act as a pathogenetically important first mutation in multistep carcinogenesis. Whenever trisomy 8 is found in malignancies, the patient should be reevaluated clinically to exclude CT8M, and CT8M patients should be monitored for the possible development of malignancies