Panel Transcript Only

This file contains the video recording of the virtual panel and discussion. The official flyer for the event is also available here and contains the panel presenter\u27s biographies

FSR19 and FSR25 confirmed as two new faint and metal-rich globular clusters in the galactic bulge

We combined the near-IR photometry from the VISTA Variables in the Vía Láctea extended Survey (VVVX) with Gaia EDR3 catalog to study some properties of FSR19 and FSR25. These are confirmed to be low luminosity metal-rich bulge globular clusters (Obasi et al. 2020). The proper motions (PM) remain unchanged and the Color magnitude diagrams (CMD) are consistent with what we previously reported and the red giant branches are narrower than the field

A REDUCED TABLEOF THE ZECH´S LOGARITHM

In this work we will solve the problem of expression of the sum of two given elements of a finite field, as power of the primitive element of the field. We obtain a reduced table of the Zech's logarithm from our proposal that relate the Zech'slogarithm with the partition of the exponents of the powers of elements over finite field ð‘®ð‘­(ð’‘ð’) in p-cyclotomic cosets modulo (ð’‘ð’−ðŸ). This reduces, in a significant way, the quantity of information to store and it facilitates its use in several cryptographic algorithms, specifically in asimetric cryptography. It is illustrated the computationof the Zech'slogarithm of any element thatdoesn't appear in the obtained reduced table

The Detector Control Systems for the CMS Resistive Plate Chamber

The Resistive Plate Chamber system is composed by 912 double-gap chambers equipped with about $10^4$ front-end boards. The correct and safe operation of the RPC system requires a sophisticated and complex online Detector Control System, able to monitor and control 2$\cdot10^4$ hardware devices distributed on an area of about 5000 m$^2$. The RPC DCS acquires, monitors and stores about $10^5$ parameters coming from the detector, the electronics, the power system, the gas, and cooling systems. The DCS system and the first results, obtained during the 2007 and 2008 CMS cosmic runs, will be described in this paper

ANTIFUNGAL ACTIVITY OF CHLOROFORM AND ACETONE EXTRACTS OF SOLANUM DOLICHOSEPALUM AGAINST FUSARIUM OXYSPORUM

Objective: Evaluate the effectiveness of acetone (A) and chloroform (C) extracts of the plant Solanum dolichosepalum to control two isolated strains (S1 and S2), each from different specimen passiflora of the fungus Fusarium oxysporum.Methods: The extracts of S. dolichosepalum were obtained by Soxhlet-solid-liquid extraction and their antifungal activity and minimum inhibitory concentrations against F. oxysporum determined by the diffusion method in potato-dextrose agar using fluconazole (60 μg/ml) as a positive control.Results: Both acetone and chloroform extracts of S. dolichosepalum presented antifungal effect on the two evaluated strains of F. oxysporum, exhibiting percentages of inhibition ranging between 33% and 95%, depending on extract concentration. It was found that extract C was more effective against S1 with a minimum inhibitory concentration (MIC) equal to 0.1558 g/ml, while extract A showed a greater inhibitory effect on S2 with a MIC = 0.1939 g/ml.Conclusion: Extracts in chloroform and acetone of the plant S. dolichosepalum were shown to be effective media to control strains of the fungus F. oxysporum. The effectiveness of these extracts to control fungi is comparable to the antifungal activity measured in the extracts of other related species

Blocking IL-17: A Promising Strategy in the Treatment of Systemic Rheumatic Diseases

Systemic rheumatic diseases are a heterogeneous group of autoimmune disorders that affect the connective tissue, characterized by the involvement of multiple organs, leading to disability, organ failure and premature mortality. Despite the advances in recent years, the therapeutic options for these diseases are still limited and some patients do not respond to the current treatments. Interleukin-17 (IL-17) is a cytokine essential in the defense against extracellular bacteria and fungi. Disruption of IL-17 homeostasis has been associated with the development and progression of rheumatic diseases, and the approval of different biological therapies targeting IL-17 for the treatment of psoriatic arthritis (PsA) and ankylosing spondylitis (AS) has highlighted the key role of this cytokine. IL-17 has been also implicated in the pathogenesis of systemic rheumatic diseases, including systemic lupus erythematosus (SLE), Sjogren's syndrome (SS) and systemic sclerosis (SSc). The aim of this review is to summarize and discuss the most recent findings about the pathogenic role of IL-17 in systemic rheumatic and its potential use as a therapeutic option

Differential gene expression in the cortical sulcus compared to the gyral crest within the early stages of chronic traumatic encephalopathy

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative tauopathy found in individuals with a history of repetitive head impacts (RHI). Previous work has demonstrated that neuroinflammation is involved in CTE pathogenesis, however, the specific inflammatory mechanisms are still unclear. Here, using RNA-sequencing and gene set enrichment analysis (GSEA), we investigated the genetic changes found in tissue taken from the region CTE pathology is first found, the cortical sulcus, and compared it to neighboring gryal crest tissue to identify what pathways were directly related to initial hyperphosphorylated tau (p-tau) deposition. 21 cases were chosen for analysis: 6 cases had no exposure to RHI or presence of neurodegenerative disease (Control), 5 cases had exposure to RHI but no presence of neurodegenerative disease (RHI), and 10 cases had exposure to RHI and low stage CTE (CTE). Two sets of genes were identified: genes that changed in both the sulcus and crest and genes that changed specifically in the sulcus relative to the crest. When examining genes that changed in both the sulcus and crest, GSEA demonstrated an increase in immune related processes and a decrease in neuronal processes in RHI and CTE groups. Sulcal specific alterations were observed to be driven by three mechanisms: anatomy, RHI, or p-tau. First, we observed consistent sulcal specific alterations in immune, extracellular matrix, vascular, neuronal, and endocytosis/exocytosis categories across all groups, suggesting the sulcus has a unique molecular signature compared to the neighboring crest independent of pathology. Second, individuals with a history of RHI demonstrated impairment in metabolic and mitochondrial related processes. Finally, in individuals with CTE, we observed impairment of immune and phagocytic related processes. Overall, this work provides the first observation of biological processes specifically altered in the sulcus that could be directly implicated in CTE pathogenesis and provide novel targets for biomarkers and therapies

Employment Expectations and Gross Flows by Type of Work Contract

There is growing interest in understanding firms’ temporary and permanent employment practices and how institutional changes shape them. Using data on Spanish establishments, we examine: (a) how employers adjust temporary and permanent job and worker flows to prior employment expectations, and (b) how the 1994 and 1997 labour reforms promoting permanent employment affected establishments’ employment practices. Generally, establishments’ prior employment expectations are realized through changes in all job and worker flows. However, establishments uniquely rely on temporary hires as a buffer to confront diminishing long-run employment expectations. None of the reforms significantly affected establishments’ net temporary or permanent employment flows.http://deepblue.lib.umich.edu/bitstream/2027.42/40032/3/wp646.pd

Laser performance of pyrromethene 567 dye in solid polymeric matrices with different cross-linking degrees

We report on the laser action of pyrromethene 567 ͑PM567͒ incorporated into copolymers of methyl methacrylate ͑MMA͒ with different methacrylic and acrylic cross-linking monomers: ethyleneglycol dimethacrylate, trimethylolpropane trimethacrylate, tetraethyleneglycol diacrylate, pentaerythritol triacrylate, and pentaerythritol tetraacrylate ͑PETRA͒. The vol/vol proportion of the different co-monomers in each copolymer formulation was systematically varied, and the effect of each composition on the lasing properties of PM567 was evaluated. The laser samples were transversely pumped at 534 nm with 5.5 mJ/pulse from a frequency doubled Q-switched Nd:KGW laser. Lasing efficiencies of up 26% and good stability with a drop of the initial laser output of 30% after 100 000 pump pulses at 5 Hz in P͑MMA:PETRA 95:5͒ were demonstrated