Effects of land use on water quality: Summit Creek, Smithfield, Utah

The effects of various land uses on water quality in Summit Creek were evaluated during the period beginning March 13, 1971, and ending October 27, 1971. Potential sources of pollution investigated where: (1) septic tank use, (2) feedlot runoff, (3) urban runoff, (4) rural runoff. Samples were collected from five sampling stations on 16 separate days during the sampling period. Analyses were performed to determine the following constituents: ammonia, nitrite, nitrate, total phosphorus, orthophosphate, coliform bacteria, chloride, suspended solids, volatile suspended solids, total carbon, organic carbon, temperature, and pH. Agricultural activates, including livestock feedlot operations, were identified as the major source of pollutant inputs to Summit Creek. No significant pollutant inputs could be attributed to septic tank use, urban runoff, or rural runoff

Reconfigurable antenna pattern verification

A method of verifying programmable antenna configurations is disclosed. The method comprises selecting a desired antenna configuration from a plurality of antenna configuration patterns, with the selected antenna configuration forming at least one reconfigurable antenna from reconfigurable antenna array elements. The method validates the formation of the selected antenna configuration to determine antenna performance of the at least one reconfigurable antenna

Antenna reconfiguration verification and validation

A method of testing the electrical functionality of an optically controlled switch in a reconfigurable antenna is provided. The method includes configuring one or more conductive paths between one or more feed points and one or more test point with switches in the reconfigurable antenna. Applying one or more test signals to the one or more feed points. Monitoring the one or more test points in response to the one or more test signals and determining the functionality of the switch based upon the monitoring of the one or more test points

Transient study using LoTSS -- framework development and preliminary results

We present a search for transient radio sources on time-scales of seconds to hours at 144 MHz using the LOFAR Two-metre Sky Survey (LoTSS). This search is conducted by examining short time-scale images derived from the LoTSS data. To allow imaging of LoTSS on short time-scales, a novel imaging and filtering strategy is introduced. This includes sky model source subtraction, no cleaning or primary beam correction, a simple source finder, fast filtering schemes and source catalogue matching. This new strategy is first tested by injecting simulated transients, with a range of flux densities and durations, into the data. We find the limiting sensitivity to be 113 and 6 mJy for 8 second and 1 hour transients respectively. The new imaging and filtering strategies are applied to 58 fields of the LoTSS survey, corresponding to LoTSS-DR1 (2% of the survey). One transient source is identified in the 8 second and 2 minute snapshot images. The source shows one minute duration flare in the 8 hour observation. Our method puts the most sensitive constraints on/estimates of the transient surface density at low frequencies at time-scales of seconds to hours; $<4.0\cdot 10^{-4} \; \text{deg}^{-2}$ at 1 hour at a sensitivity of 6.3 mJy; $5.7\cdot 10^{-7} \; \text{deg}^{-2}$ at 2 minutes at a sensitivity of 30 mJy; and $3.6\cdot 10^{-8} \; \text{deg}^{-2}$ at 8 seconds at a sensitivity of 113 mJy. In the future, we plan to apply the strategies presented in this paper to all LoTSS data.Comment: submitted to MNRA

Leiomyosarcoma of the inferior vena cava: a case report and review of the literature

A 68-year-old white female presented with two years of progressively worsening dyspnea. Echocardiography revealed a large right atrial mass and partial obstruction of the inferior vena cava. Further imaging revealed a cystic dense mass in the inferior vena cava and right atrium. Immunohistochemical stains were consistent with leiomyosarcoma. Intraoperatively, the tumor was noted to originate from the posterior aspect of the inferior vena cava. The patient underwent successful resection of the mass. Adjuvant radiation therapy was completed. The patient's dyspnea gradually improved and she continues to remain disease free five years post-resection

The Lantern Vol. 31, No. 1, December 1963

• Today\u27s Memory • The Realization • Life Fire • Come Sleep • The Ends Meet • Dawn of Darkness • Closed and Done: With Apologies to No One • A Search • Concern • Obvious Oblivion • Love\u27s Ashes • Silence • To My Dentist • Snow • Wisdom • Look Up • Nepenthe • With Apologies to Charles Schulz • Autumn and You • What is Optimism? • Agnostic? • Potpourri of Beinghttps://digitalcommons.ursinus.edu/lantern/1085/thumbnail.jp

Paradoxical enhancement of fear extinction memory and synaptic plasticity by inhibition of the histone acetyltransferase p300

It is well established that the coordinated regulation of activity-dependent gene expression by the histone acetyltransferase (HAT) family of transcriptional coactivators is crucial for the formation of contextual fear and spatial memory, and for hippocampal synaptic plasticity. However, no studies have examined the role of this epigenetic mechanism within the infralimbic prefrontal cortex (ILPFC), an area of the brain that is essential for the formation and consolidation of fear extinction memory. Here we report that a postextinction training infusion of a combined p300/CBP inhibitor (Lys-CoA-Tat), directly into the ILPFC, enhances fear extinction memory in mice. Our results also demonstrate that the HAT p300 is highly expressed within pyramidal neurons of the ILPFC and that the small-molecule p300-specific inhibitor (C646) infused into the ILPFC immediately after weak extinction training enhances the consolidation of fear extinction memory. C646 infused 6 h after extinction had no effect on fear extinction memory, nor did an immediate postextinction training infusion into the prelimbic prefrontal cortex. Consistent with the behavioral findings, inhibition of p300 activity within the ILPFC facilitated long-term potentiation (LTP) under stimulation conditions that do not evoke long-lasting LTP. These data suggest that one function of p300 activity within the ILPFC is to constrain synaptic plasticity, and that a reduction in the function of this HAT is required for the formation of fear extinction memory

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

Asthma resistance to glucocorticoid treatment is a major health problem with unclear etiology. Glucocorticoids inhibit adrenal androgen production. However, androgens have potential benefits in asthma. HSD3B1 encodes for 3β-hydroxysteroid dehydrogenase-1 (3β-HSD1), which catalyzes peripheral conversion from adrenal dehydroepiandrosterone (DHEA) to potent androgens and has a germline missense-encoding polymorphism. The adrenal restrictive HSD3B1(1245A) allele limits conversion, whereas the adrenal permissive HSD3B1(1245C) allele increases DHEA metabolism to potent androgens. In the Severe Asthma Research Program (SARP) III cohort, we determined the association between DHEA-sulfate and percentage predicted forced expiratory volume in 1 s (FEV1PP). HSD3B1(1245) genotypes were assessed, and association between adrenal restrictive and adrenal permissive alleles and FEV1PP in patients with (GC) and without (noGC) daily oral glucocorticoid treatment was determined (n = 318). Validation was performed in a second cohort (SARP I&II; n = 184). DHEA-sulfate is associated with FEV1PP and is suppressed with GC treatment. GC patients homozygous for the adrenal restrictive genotype have lower FEV1PP compared with noGC patients (54.3% vs. 75.1%; P < 0.001). In patients with the homozygous adrenal permissive genotype, there was no FEV1PP difference in GC vs. noGC patients (73.4% vs. 78.9%; P = 0.39). Results were independently confirmed: FEV1PP for homozygous adrenal restrictive genotype in GC vs. noGC is 49.8 vs. 63.4 (P < 0.001), and for homozygous adrenal permissive genotype, it is 66.7 vs. 67.7 (P = 0.92). The adrenal restrictive HSD3B1(1245) genotype is associated with GC resistance. This effect appears to be driven by GC suppression of 3β-HSD1 substrate. Our results suggest opportunities for prediction of GC resistance and pharmacologic intervention