Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and ε-aminocaproic acid - a meta-analysis of randomised and observational trials of over 30.000 patients

Background: To compare the effect of aprotinin with the effect of lysine analogues (tranexamic acid and ε-aminocaproic acid) on early mortality in three subgroups of patients: low, intermediate and high risk of cardiac surgery. Methods and Findings: We performed a meta-analysis of randomised controlled trials and observational with the following data sources: Medline, Cochrane Library, and reference lists of identified articles. The primary outcome measure was early (in-hospital/30-day) mortality. The secondary outcome measures were any transfusion of packed red blood cells within 24 hours after surgery, any re-operation for bleeding or massive bleeding, and acute renal dysfunction or failure within the selected cited publications, respectively. Out of 328 search results, 31 studies (15 trials and 16 observational studies) included 33,501 patients. Early mortality was significantly increased after aprotinin vs. lysine analogues with a pooled risk ratio (95% CI) of 1.58 (1.13–2.21), p<0.001 in the low (n = 14,297) and in the intermediate risk subgroup (1.42 (1.09–1.84), p<0.001; n = 14,427), respectively. Contrarily, in the subgroup of high risk patients (n = 4,777), the risk for mortality did not differ significantly between aprotinin and lysine analogues (1.03 (0.67–1.58), p = 0.90). Conclusion: Aprotinin may be associated with an increased risk of mortality in low and intermediate risk cardiac surgery, but presumably may has no effect on early mortality in a subgroup of high risk cardiac surgery compared to lysine analogues. Thus, decisions to re-license aprotinin in lower risk patients should critically be debated. In contrast, aprotinin might probably be beneficial in high risk cardiac surgery as it reduces risk of transfusion and bleeding complications

The Cephennium fauna of Turkey and the Middle East (Coleoptera: Staphylinidae: Scydmaeninae)

Lediglich zwei Arten der Gattung Cephennium Müller &amp; Kunze, 1822 waren bislang aus der Türkei und dem Nahen Osten (Libanon, Israel, Jordanien, Irak, Iran) bekannt. Die Bearbeitung von Material, das auf zahlreichen Forschungsreisen in die Türkei und nach Jordanien in den vergangenen vier Jahrzehnten gesammelt wurde, ergab, dass die Cephennium-Fauna insbesondere der Türkei bemerkenswert divers ist. Insgesamt 25 benannte Arten werden unterschieden, abgebildet und vier Artengruppen zugeordnet. Zoogeographische, morphologische und weitere Argumente legen nahe, dass C. bodemeyeri Reitter, 1903, bisher Unterart von C. perispinctum Kolenati, 1846, als distinkte Art zu betrachten ist. Dreiundzwanzig Arten werden erstmals beschrieben: Cephennium fractum spec. nov. (Türkei: Bursa, Balıkesir, Kocaeli, Çanakkale), C. infractum spec. nov. (Türkei: Bursa) und C. immutatum spec. nov. (Türkei: Izmir, Muğla, Adıyaman) aus der C. perispinctum-Gruppe; C. ericinum spec. nov. (Türkei: Ordu), C. varispinosum spec. nov. (Türkei: Ordu), C. victrix spec. nov. (Türkei: Sinop), C. spinigerum spec. nov. (Türkei: Bartin) und C. digitale spec. nov. (Türkei: Zonguldak) aus der C. ericinum-Gruppe; C. reductum spec. nov. (Türkei: Konya, Antalya, Mersin, Kastamonu) aus der C. jonicum-Gruppe; C. corruptum spec. nov. (Türkei: Mersin, Adana), C. marasicum spec. nov. (Türkei: Kahramanmaraş), C. dolucanum spec. nov. (Türkei: Kahramanmaraş), C. fimbriatum spec. nov. (Türkei: Adana), C. besucheti spec. nov. (Türkei: Kahramanmaraş), C. affimbriatum spec. nov. (Türkei: Kahramanmaraş), C. kartalicum spec. nov. (Türkei: Gaziantep), Cephennium nemruticum spec. nov. (Türkei: Adıyaman), C. unguicum spec. nov. (Türkei: Aydın), C. deplectens spec. nov. (Türkei: Izmir, Manisa), C. sicaferum spec. nov. (Türkei: Aydın), C. geminum spec. nov. (Türkei: Antalya), C. duplum spec. nov. (Türkei: Muğla), und C. jordanicum spec. nov. (Nordwest-Jordanien) aus der C. corruptum-Gruppe. Einige weitere, ausschließlich durch Weibchen vertretene und wahrscheinlich zur C. corruptum-Gruppe gehörende Arten bleiben unbenannt. Für die beschriebenen Cephennium-Arten der Türkei und des Nahen Ostens wird eine Bestimmungstabelle erstellt. Die Verbreitungsgebiete der aus der Türkei nachgewiesenen Arten werden anhand von Karten illustriert. In einem Anhang wird C. liguliferum spec. nov. (Südost-Bulgarien), eine mit C. bodemeyeri and C. perispinctum nah verwandte Art, beschrieben und abgebildet. Taxonomische Handlungen Cephennium fractum spec. nov. – urn:lsid:zoobank.org:act:26CE8301-2927-4893-B93E-9F2BEF4F7F07Cephennium infractum spec. nov. – urn:lsid:zoobank.org:act:E222C4A2-D6AC-48FF-AC4C-B274EF405209Cephennium immutatum spec. nov. – urn:lsid:zoobank.org:act:F24C0315-7B6F-427E-B9AB-65AB304F7718Cephennium ericinum spec. nov. – urn:lsid:zoobank.org:act:F56474A9-C330-4019-BD58-B566E66CF58ECephennium varispinosum spec. nov. – urn:lsid:zoobank.org:act:04C4304D-F84A-400B-8710-15407DE9BCCDCephennium victrix spec. nov. – urn:lsid:zoobank.org:act:2BC2443C-70A2-4B5B-874A-FAF0F4DCFB62Cephennium spinigerum spec. nov. – urn:lsid:zoobank.org:act:7321FC90-18ED-4F50-8CFA-58F338EA62BBCephennium digitale spec. nov. – urn:lsid:zoobank.org:act:06ED0DE9-D72E-410C-9A7A-B7330175D3D9Cephennium reductum spec. nov. – urn:lsid:zoobank.org:act:CB292C96-5EC1-4947-AE0F-3D3F3094C77ACephennium corruptum spec. nov. – urn:lsid:zoobank.org:act:BC5C6DE3-2696-4949-B84F-E7336C5DC774Cephennium marasicum spec. nov. – urn:lsid:zoobank.org:act:02420408-99DB-49FA-8A5B-409528E5613ACephennium dolucanum spec. nov. – urn:lsid:zoobank.org:act:F0BFE9A7-0AE9-40D2-BC5E-49DE875B2A65Cephennium fimbriatum spec. nov. – urn:lsid:zoobank.org:act:831C051F-751A-4D9C-A9DA-7E2BCAA4D82ECephennium besucheti spec. nov. – urn:lsid:zoobank.org:act:831C051F-751A-4D9C-A9DA-7E2BCAA4D82ECephennium affimbriatum spec. nov. – urn:lsid:zoobank.org:act:02ED0B80-53CF-4ED8-8648-F45DC12696B5Cephennium kartalicum spec. nov. – urn:lsid:zoobank.org:act:27B66398-BD3C-4C54-9DF8-0918EEEB6C65Cephennium nemruticum spec. nov. – urn:lsid:zoobank.org:act:643B8783-90BC-4DE2-9DA7-45EFCF67778CCephennium unguicum spec. nov. – urn:lsid:zoobank.org:act:92FD91A3-6A6F-4EBB-BBBF-2CA222D6FD14Cephennium deplectens spec. nov. – urn:lsid:zoobank.org:act:E16431E9-E6B9-411F-B164-3FA1B7A4D2E2Cephennium sicaferum spec. nov. – urn:lsid:zoobank.org:act:7F1029CB-AD9C-42A6-BBAC-5BDC653EBFECCephennium geminum spec. nov. – urn:lsid:zoobank.org:act:36759AD0-8CA5-44E3-A0A0-D50329D09B0CCephennium duplum spec. nov. – urn:lsid:zoobank.org:act:B2B65A3E-757E-44EB-9F6F-C46D7523A3EBCephennium jordanicum spec. nov. – urn:lsid:zoobank.org:act:900BF391-A399-4559-A132-F1E8F1CFB3E7Cephennium liguliferum spec. nov. – urn:lsid:zoobank.org:act:BE39D1DA-3677-435F-A8EB-D34BE361F9F5 &nbsp;Only two species of Cephennium Muller &amp; Kunze, 1822 were previously known from Turkey and the Middle East including Lebanon, Israel, Jordan, Iraq, and Iran. An examination of material collected during numerous field trips toTurkey and Jordan in the past four decades revealed that the Cephennium fauna of Turkey is remarkably diverse. In total, 25 named species are recognized, diagnosed, illustrated, and assigned to four species groups. Based on zoogeographic, morphological, and additional evidence, C. bodemeyeri Reitter, 1903, previously a subspecies of C. perispinctum Kolenati, 1846, is elevated to species rank. Twenty-three species are described for the first time: Cephennium fractum spec. nov. (Turkey: Bursa, Balıkesir, Kocaeli, Canakkale), C. infractum spec. nov. (Turkey: Bursa), and C. immutatum spec. nov. (Turkey: Izmir, Muğla, Adıyaman) of the C. perispinctum group; C. ericinum spec. nov. (Turkey: Ordu), C. varispinosum spec. nov. (Turkey: Ordu), C. victrix spec. nov. (Turkey: Sinop), C. spinigerum spec. nov. (Turkey: Bartin), and C. digitale spec. nov. (Turkey: Zonguldak) of the C. ericinum group; C. reductum spec. nov. (Turkey: Konya, Antalya, Mersin, Kastamonu) of the C. jonicum group; C. corruptum spec. nov. (Turkey: Mersin, Adana), C. marasicum spec. nov. (Turkey: Kahramanmaraş), C. dolucanum spec. nov. (Turkey: Kahramanmaraş), C. fimbriatum spec. nov. (Turkey: Adana), C. besucheti spec. nov. (Turkey: Kahramanmaraş), C. affimbriatum spec. nov. (Turkey: Kahramanmaraş), C. kartalicum spec. nov. (Turkey: Gaziantep), Cephennium nemruticum spec. nov. (Turkey: Adıyaman), C. unguicum spec. nov. (Turkey: Aydın), C. deplectens spec. nov. (Turkey: Izmir, Manisa), C. sicaferum spec. nov. (Turkey: Aydın), C. geminum spec. nov. (Turkey: Antalya), C. duplum spec. nov. (Turkey: Muğla), and C. jordanicum spec. nov. (Northwest Jordan) of the C. corruptum group. Several additional species, all of them represented exclusively by females and most likely belonging to the C. corruptum group, remain undescribed. A key to the named species of Turkey and the Middle East is provided. The distributions of the species recorded from Turkey are mapped. In an appendix, C. liguliferum spec. nov. (Southeast Bulgaria), a close relative of C. bodemeyeri and C. perispinctum, is described and illustrated. Taxonomic acts Cephennium fractum spec. nov. – urn:lsid:zoobank.org:act:26CE8301-2927-4893-B93E-9F2BEF4F7F07Cephennium infractum spec. nov. – urn:lsid:zoobank.org:act:E222C4A2-D6AC-48FF-AC4C-B274EF405209Cephennium immutatum spec. nov. – urn:lsid:zoobank.org:act:F24C0315-7B6F-427E-B9AB-65AB304F7718Cephennium ericinum spec. nov. – urn:lsid:zoobank.org:act:F56474A9-C330-4019-BD58-B566E66CF58ECephennium varispinosum spec. nov. – urn:lsid:zoobank.org:act:04C4304D-F84A-400B-8710-15407DE9BCCDCephennium victrix spec. nov. – urn:lsid:zoobank.org:act:2BC2443C-70A2-4B5B-874A-FAF0F4DCFB62Cephennium spinigerum spec. nov. – urn:lsid:zoobank.org:act:7321FC90-18ED-4F50-8CFA-58F338EA62BBCephennium digitale spec. nov. – urn:lsid:zoobank.org:act:06ED0DE9-D72E-410C-9A7A-B7330175D3D9Cephennium reductum spec. nov. – urn:lsid:zoobank.org:act:CB292C96-5EC1-4947-AE0F-3D3F3094C77ACephennium corruptum spec. nov. – urn:lsid:zoobank.org:act:BC5C6DE3-2696-4949-B84F-E7336C5DC774Cephennium marasicum spec. nov. – urn:lsid:zoobank.org:act:02420408-99DB-49FA-8A5B-409528E5613ACephennium dolucanum spec. nov. – urn:lsid:zoobank.org:act:F0BFE9A7-0AE9-40D2-BC5E-49DE875B2A65Cephennium fimbriatum spec. nov. – urn:lsid:zoobank.org:act:831C051F-751A-4D9C-A9DA-7E2BCAA4D82ECephennium besucheti spec. nov. – urn:lsid:zoobank.org:act:831C051F-751A-4D9C-A9DA-7E2BCAA4D82ECephennium affimbriatum spec. nov. – urn:lsid:zoobank.org:act:02ED0B80-53CF-4ED8-8648-F45DC12696B5Cephennium kartalicum spec. nov. – urn:lsid:zoobank.org:act:27B66398-BD3C-4C54-9DF8-0918EEEB6C65Cephennium nemruticum spec. nov. – urn:lsid:zoobank.org:act:643B8783-90BC-4DE2-9DA7-45EFCF67778CCephennium unguicum spec. nov. – urn:lsid:zoobank.org:act:92FD91A3-6A6F-4EBB-BBBF-2CA222D6FD14Cephennium deplectens spec. nov. – urn:lsid:zoobank.org:act:E16431E9-E6B9-411F-B164-3FA1B7A4D2E2Cephennium sicaferum spec. nov. – urn:lsid:zoobank.org:act:7F1029CB-AD9C-42A6-BBAC-5BDC653EBFECCephennium geminum spec. nov. – urn:lsid:zoobank.org:act:36759AD0-8CA5-44E3-A0A0-D50329D09B0CCephennium duplum spec. nov. – urn:lsid:zoobank.org:act:B2B65A3E-757E-44EB-9F6F-C46D7523A3EBCephennium jordanicum spec. nov. – urn:lsid:zoobank.org:act:900BF391-A399-4559-A132-F1E8F1CFB3E7Cephennium liguliferum spec. nov. – urn:lsid:zoobank.org:act:BE39D1DA-3677-435F-A8EB-D34BE361F9F

Monograph of the Staphylinidae of Crete (Greece). Part II. Descriptions of new species (Insecta: Coleoptera)

Eine Gattung, Cretotyphlus Assing gen. nov., und 48 Arten der Staphylinidae von der griechischen Insel Kreta, davon 47 Insel- oder Lokalendemiten, werden beschrieben und abgebildet: Amischa cretica Assing spec. nov., Atheta (Anopleta) digitalis Assing spec. nov., Hydrosmecta insularum Assing spec. nov. (Kreta, Ikaria, Lesbos, Samothraki), Geostiba (Sipalotricha) inexsecta Assing spec. nov. (Gebiet ost-südöstlich von Rethimno), Cousya candica Assing spec. nov. (Ostkreta: Dikti), Oxypoda (Bessopora) bimontium Assing spec. nov. (Dikti, Psiloritis), O. (Mycetodrepa) retunsa Assing spec. nov. und Typhlocyptus creticus Assing spec. nov. aus der Unterfamilie Aleocharinae; Geomitopsis cretica Assing spec. nov. (Ostkreta) (Osoriinae); Allotyphlus (Moreotyphlus) foedatus Assing spec. nov. (Westkreta), Kenotyphlus virgatus Assing spec. nov. (Westkreta), Cretotyphlus hamatus Assing spec. nov. (Ostkreta: Dikti), C. chanianus Assing spec. nov. (Gebiet südwestlich von Chania) und C. idanus Assing spec. nov. (Zentralkreta: Psiloritis) aus der Unterfamilie Leptotyphlinae; Pseudobium creticum Assing spec. nov. (Paederinae); Gabrius candicus Assing spec. nov. (Staphylininae); Cephennium arcuatum Assing spec. nov. (Ostkreta), C. thripticum Assing spec. nov. (Ostkreta: Thripti), C. selinonum Assing spec. nov. (Sudwestkreta), C. meybohmi Assing spec. nov. (Westkreta), C. idanum Assing spec. nov. (Zentralkreta: Psiloritis), C. sinuosum Assing spec. nov. (Ostkreta), C. fortespinosum Assing spec. nov. (Ostkreta), C. hamulatum Assing spec. nov. (Ostkreta: Dikti), C. curvatum Assing spec. nov. (Ostkreta), C. selenanum Assing spec. nov. (Ostkreta: Selena Oros), C. latius Assing spec. nov. (Zentralkreta: Psiloritis), C. chanianum Assing spec. nov. (Westkreta), Euconnus (Tetramelus) zakrius Meybohm spec. nov. (Ostkreta), Stenichnus (Stenichnus) brachati Meybohm spec. nov., S. (S.) orientalis Meybohm spec. nov. (Ostkreta), S. (S.) aegialioides Meybohm spec. nov., Leptomastax cretica Meybohm spec. nov. und L. thriptica Meybohm spec. nov. (Ostkreta: Thripti) aus der Unterfamilie Scydmaeninae; Afropselaphus doernfeldae Brachat spec. nov. (Westkreta: Lefka Ori), A. assingi Brachat spec. nov. (Westkreta: Lefka Ori), A. diktianus Brachat spec. nov. (Ostkreta: Dikti), A. thripticus Brachat spec. nov. (Ostkreta: Thripti), Amauronyx chanianus Brachat spec. nov. (Westkreta), A. occidens Brachat spec. nov. (Westkreta), A. askifouicus Brachat spec. nov. (Westkreta), Bryaxis meybohmianus Brachat spec. nov. (Westkreta), Bythinus creticus Brachat spec. nov. (Zentralkreta: Psiloritis), Euplectus assingi Brachat spec. nov. (Kreta), Faronus meybohmi Brachat spec. nov. (Westkreta: Lefka Ori), F. lefkamontium Brachat spec. nov. (Westkreta: Lefka Ori), F. albimontium Brachat spec. nov. (Westkreta: Lefka Ori) und Tychus chanianus Brachat spec. nov. (Westkreta) aus der Unterfamilie Pselaphinae; Sepedophilus creticus Schülke spec. nov. (Tachyporinae). Für die von Kreta nachgewiesenen Arten der Gattungen Cephennium Müller &amp; Kunze, 1822 und Stenichnus Thomson, 1859 werden Bestimmungstabellen erstellt. Für Amauronyx paganettii Blattny &amp; Blattny, 1916 wird ein Lektotypus designiert. &nbsp; Nomenklatorische Handlungen Cretotyphlus Assing gen. nov. – urn:lsid:zoobank.org:act:FD86523B-3B04-43D4-BD1B-40BC18EAD15FAmischa cretica Assing spec. nov. – urn:lsid:zoobank.org:act:1DBCBA49-3E09-4665-97CC-4641BB816F4EAtheta digitalis Assing spec. nov. – urn:lsid:zoobank.org:act:E1F1F8FC-708F-4C1B-AF02-5A83EC6E5A0DHydrosmecta insularum Assing spec. nov. – urn:lsid:zoobank.org:act:A5DC3A8F-AC05-46F0-B3D0-A97CF126AB8FGeostiba inexsecta Assing spec. nov. – urn:lsid:zoobank.org:act:35864FAC-C639-4F3A-B0CA-AAB83AEBFD36Cousya candica Assing spec. nov. – urn:lsid:zoobank.org:act:44B00621-3DA4-462B-9491-AD4B45476F2EOxypoda bimontium Assing spec. nov. – urn:lsid:zoobank.org:act:C38F6606-DE88-4E86-B1E8-AB0921804654Oxypoda retunsa Assing spec. nov. – urn:lsid:zoobank.org:act:D801AADC-CC6A-4E15-8988-BE8CCEA48013Typhlocyptus creticus Assing spec. nov. – urn:lsid:zoobank.org:act:2F3A6D48-5EA3-417D-9DB3-F8E0139432F6Geomitopsis cretica Assing spec. nov. – urn:lsid:zoobank.org:act:1D3E575E-A726-422D-BA91-AF9B98BCA2BDAllotyphlus foedatus Assing spec. nov. – urn:lsid:zoobank.org:act:42A89E7C-F33A-43C8-A301-296D27AD2BBFKenotyphlus virgatus Assing spec. nov. – urn:lsid:zoobank.org:act:1967E04F-CD26-4976-928F-B9A195790332Cretotyphlus hamatus Assing spec. nov. – urn:lsid:zoobank.org:act:EBE1B406-3145-411C-883D-A9499AEF52BACretotyphlus chanianus Assing spec. nov. – urn:lsid:zoobank.org:act:1D048CF4-D0DE-4839-869F-4D96B269F25CCretotyphlus idanus Assing spec. nov. – urn:lsid:zoobank.org:act:993DEFB4-903E-4367-96DD-6F4D8F0DE42FPseudobium creticum Assing spec. nov. – urn:lsid:zoobank.org:act:98EA1ABE-EA17-4F90-A7BF-6069D9FDF481Gabrius candicus Assing spec. nov. – urn:lsid:zoobank.org:act:4FAC0FC1-20F7-4DC4-BAA9-FBC4DDF3175DCephennium arcuatum Assing spec. nov. – urn:lsid:zoobank.org:act:7A3212BC-0311-49F7-A2AB-C529B6CD42A9Cephennium thripticum Assing spec. nov. – urn:lsid:zoobank.org:act:6681B4E6-3602-47F6-82BF-C1C9FD0E6A45Cephennium selinonum Assing spec. nov. – urn:lsid:zoobank.org:act:5C1D00CC-C8A3-4043-92A9-773137CD17CBCephennium meybohmi Assing spec. nov. – urn:lsid:zoobank.org:act:BDCAA375-E045-47F7-AC38-6812249B9A7CCephennium idanum Assing spec. nov. – urn:lsid:zoobank.org:act:C7F685DD-32CC-4AF7-AA4E-4B3096D86B13Cephennium sinuosum Assing spec. nov. – urn:lsid:zoobank.org:act:C89E57D1-33EB-4693-BF85-27EAC289A064Cephennium fortespinosum Assing spec. nov. – urn:lsid:zoobank.org:act:C84F5038-F12C-48CC-9ED7-8DBE6BAE1D5CCephennium hamulatum Assing spec. nov. – urn:lsid:zoobank.org:act:FA4D9AB5-DAA3-4DE7-8064-5B98210F93D0Cephennium curvatum Assing spec. nov. – urn:lsid:zoobank.org:act:73B78F2A-4907-4334-B475-A59C7CD81063Cephennium selenanum Assing spec. nov. – urn:lsid:zoobank.org:act:E5B87D2D-9402-43F9-82E3-1DEF6D709DF1Cephennium latius Assing spec. nov. – urn:lsid:zoobank.org:act:8B3A0458-1D50-4551-BED6-D307750DD522Cephennium chanianum Assing spec. nov. – urn:lsid:zoobank.org:act:0C990A58-8107-4B07-87D5-FE0541CD444Euconnus zakrius Meybohm spec. nov. – urn:lsid:zoobank.org:act:506C3D6D-FD24-4484-813D-F00E761EFECBStenichnus brachati Meybohm spec. nov. – urn:lsid:zoobank.org:act:0D694A13-AB82-4398-AC2A-2E4D39B515FBStenichnus orientalis Meybohm spec. nov. – urn:lsid:zoobank.org:act:06558FCA-3A62-4019-BFB7-EF06448C1956Stenichnus aegialioides Meybohm spec. nov. – urn:lsid:zoobank.org:act:712D1FB1-7AB4-4C27-8CB2-05E07E8435FELeptomastax cretica Meybohm spec. nov. – urn:lsid:zoobank.org:act:444B05D8-E8CB-4F7F-A9A5-1695EB36C08ALeptomastax thriptica Meybohm spec. nov. – urn:lsid:zoobank.org:act:5EA83082-7F64-4122-852C-AECB11BF6D01Afropselaphus doernfeldae Brachat spec. nov. – urn:lsid:zoobank.org:act:96DFC249-A208-44CE-BC83-4BB829F6966BAfropselaphus assingi Brachat spec. nov. – urn:lsid:zoobank.org:act:A29A770B-1104-4BB0-BA7E-ADA1CB04D204Afropselaphus diktianus Brachat spec. nov. – urn:lsid:zoobank.org:act:AF308CB8-7539-4626-8E2CDD2A7E9B5052Afropselaphus thripticus Brachat spec. nov. – urn:lsid:zoobank.org:act:E38E8556-0E8F-4C12-BD99-3759694D8E82 Amauronyx chanianus Brachat spec. nov. – urn:lsid:zoobank.org:act:833A774F-4626-4CC8-8BE0-7B857E33EC43Amauronyx occidens Brachat spec. nov. – urn:lsid:zoobank.org:act:0545A123-B114-4014-A05D-2C5EF565D5D9Amauronyx askifouicus Brachat spec. nov. – urn:lsid:zoobank.org:act:7CE4D2AD-8F1E-408A-9112-5301AC6CC6AEBryaxis meybohmianus Brachat spec. nov. – urn:lsid:zoobank.org:act:FE6B56D3-E7A1-4F55-9587-ABC42768A1ACBythinus creticus Brachat spec. nov. – urn:lsid:zoobank.org:act:5A5439A5-BB04-41D0-897E-3769BA046964Euplectus assingi Brachat spec. nov. – urn:lsid:zoobank.org:act:B653CFCD-0DF4-4AC8-8BDC-64FCD2FB9599Faronus meybohmi Brachat spec. nov. – urn:lsid:zoobank.org:act:B80022A7-78AC-45E9-94A6-B3A31657DCF7Faronus lefkamontium Brachat spec. nov. – urn:lsid:zoobank.org:act:B5C36287-54F6-4CF0-B2BF-E3D8E4AF1029Faronus albimontium Brachat spec. nov. – urn:lsid:zoobank.org:act:9E7893E5-D3A1-4387-B179-AA51AB793FEDTychus chanianus Brachat spec. nov. – urn:lsid:zoobank.org:act:85D07E45-AEE2-4D13-9C26-18B353D1AD15Sepedophilus creticus Schülke spec. nov. – urn:lsid:zoobank.org:act:F2B971D6-B222-4823-A1BB-DF4B816F0775One genus, Cretotyphlus Assing gen. nov., and 48 species of Staphylinidae from the Greek island Crete, 47 of them island endemics or even locally endemic, are described and illustrated: Amischa cretica Assing spec. nov., Atheta (Anopleta) digitalis Assing spec. nov., Hydrosmecta insularum Assing spec. nov. (Crete, Ikaria, Lesbos, Samothraki), Geostiba (Sipalotricha) inexsecta Assing spec. nov. (region to the east-southeast of Rethimno), Cousya candica Assing spec. nov. (East Crete: Dikti), Oxypoda (Bessopora) bimontium Assing spec. nov. (Dikti, Psiloritis), O. (Mycetodrepa) retunsa Assing spec. nov., and Typhlocyptus creticus Assing spec. nov. of the Aleocharinae; Geomitopsis cretica Assing spec. nov. (East Crete) of the Osoriinae; Allotyphlus (Moreotyphlus) foedatus Assing spec. nov. (West Crete), Kenotyphlus virgatus Assing spec. nov. (West Crete), Cretotyphlus hamatus Assing spec. nov. (East Crete: Dikti), C. chanianus Assing spec. nov. (region to the southwest of Chania), and C. idanus Assing spec. nov. (Central Crete: Psiloritis) of the Leptotyphlinae; Pseudobium creticum Assing spec. nov. of the Paederinae; Gabrius candicus Assing spec. nov. Of the Staphylininae; Cephennium arcuatum Assing spec. nov. (East Crete), C. thripticum Assing spec. nov. (East Crete: Thripti), C. selinonum Assing spec. nov. (Southwest Crete), C. meybohmi Assing spec. nov. (West Crete), C. idanum Assing spec. nov. (Central Crete: Psiloritis), C. sinuosum Assing spec. nov. (East Crete), C. fortespinosum Assing spec. nov. (East Crete), C. hamulatum Assing spec. nov. (East Crete: Dikti), C. curvatum Assing spec. nov. (East Crete), C. selenanum Assing spec. nov. (East Crete: Selena Oros), C. latius Assing spec. nov. (Central Crete: Psiloritis), C. chanianum Assing spec. nov. (West Crete), Euconnus (Tetramelus) zakrius Meybohm spec. nov. (East Crete), Stenichnus (Stenichnus) brachati Meybohm spec. nov., S. (S.) orientalis Meybohm spec. nov. (East Crete), S. (S.) aegialioides Meybohm spec. nov., Leptomastax cretica Meybohm spec. nov., and L. thriptica Meybohm spec. nov. (East Crete: Thripti) of the Scydmaeninae; Afropselaphus doernfeldae Brachat spec. nov. (West Crete: Lefka Ori), A. assingi Brachat spec. nov. (West Crete: Lefka Ori), A. diktianus Brachat spec. nov. (East Crete: Dikti), A. thripticus Brachat spec. nov. (East Crete: Thripti), Amauronyx chanianus Brachat spec. nov. (West Crete), A. occidens Brachat spec. nov. (West Crete), A. askifouicus Brachat spec. nov. (West Crete), Bryaxis meybohmianus Brachat spec. nov. (West Crete), Bythinus creticus Brachat spec. nov. (Central Crete: Psiloritis), Euplectus assingi Brachat spec. nov. (Crete), Faronus meybohmi Brachat spec. nov. (West Crete: Lefka Ori), F. lefkamontium Brachat spec. nov. (West Crete: Lefka Ori), F. albimontium Brachat spec. nov. (West Crete: Lefka Ori), and Tychus chanianus Brachat spec. nov. (West Crete) of the Pselaphinae; Sepedophilus creticus Schülke spec. nov. of the Tachyporinae. Keys to the species of Cephennium Müller &amp; Kunze, 1822 and Stenichnus Thomson, 1859 of Crete are provided. A lectotype is designated for Amauronyx paganettii Blattný &amp; Blattný, 1916. &nbsp; Taxonomic acts Cretotyphlus Assing gen. nov. – urn:lsid:zoobank.org:act:FD86523B-3B04-43D4-BD1B-40BC18EAD15FAmischa cretica Assing spec. nov. – urn:lsid:zoobank.org:act:1DBCBA49-3E09-4665-97CC-4641BB816F4EAtheta digitalis Assing spec. nov. – urn:lsid:zoobank.org:act:E1F1F8FC-708F-4C1B-AF02-5A83EC6E5A0DHydrosmecta insularum Assing spec. nov. – urn:lsid:zoobank.org:act:A5DC3A8F-AC05-46F0-B3D0-A97CF126AB8FGeostiba inexsecta Assing spec. nov. – urn:lsid:zoobank.org:act:35864FAC-C639-4F3A-B0CA-AAB83AEBFD36Cousya candica Assing spec. nov. – urn:lsid:zoobank.org:act:44B00621-3DA4-462B-9491-AD4B45476F2EOxypoda bimontium Assing spec. nov. – urn:lsid:zoobank.org:act:C38F6606-DE88-4E86-B1E8-AB0921804654Oxypoda retunsa Assing spec. nov. – urn:lsid:zoobank.org:act:D801AADC-CC6A-4E15-8988-BE8CCEA48013Typhlocyptus creticus Assing spec. nov. – urn:lsid:zoobank.org:act:2F3A6D48-5EA3-417D-9DB3-F8E0139432F6Geomitopsis cretica Assing spec. nov. – urn:lsid:zoobank.org:act:1D3E575E-A726-422D-BA91-AF9B98BCA2BDAllotyphlus foedatus Assing spec. nov. – urn:lsid:zoobank.org:act:42A89E7C-F33A-43C8-A301-296D27AD2BBFKenotyphlus virgatus Assing spec. nov. – urn:lsid:zoobank.org:act:1967E04F-CD26-4976-928F-B9A195790332Cretotyphlus hamatus Assing spec. nov. – urn:lsid:zoobank.org:act:EBE1B406-3145-411C-883D-A9499AEF52BACretotyphlus chanianus Assing spec. nov. – urn:lsid:zoobank.org:act:1D048CF4-D0DE-4839-869F-4D96B269F25CCretotyphlus idanus Assing spec. nov. – urn:lsid:zoobank.org:act:993DEFB4-903E-4367-96DD-6F4D8F0DE42FPseudobium creticum Assing spec. nov. – urn:lsid:zoobank.org:act:98EA1ABE-EA17-4F90-A7BF-6069D9FDF481Gabrius candicus Assing spec. nov. – urn:lsid:zoobank.org:act:4FAC0FC1-20F7-4DC4-BAA9-FBC4DDF3175DCephennium arcuatum Assing spec. nov. – urn:lsid:zoobank.org:act:7A3212BC-0311-49F7-A2AB-C529B6CD42A9Cephennium thripticum Assing spec. nov. – urn:lsid:zoobank.org:act:6681B4E6-3602-47F6-82BF-C1C9FD0E6A45Cephennium selinonum Assing spec. nov. – urn:lsid:zoobank.org:act:5C1D00CC-C8A3-4043-92A9-773137CD17CBCephennium meybohmi Assing spec. nov. – urn:lsid:zoobank.org:act:BDCAA375-E045-47F7-AC38-6812249B9A7CCephennium idanum Assing spec. nov. – urn:lsid:zoobank.org:act:C7F685DD-32CC-4AF7-AA4E-4B3096D86B13Cephennium sinuosum Assing spec. nov. – urn:lsid:zoobank.org:act:C89E57D1-33EB-4693-BF85-27EAC289A064Cephennium fortespinosum Assing spec. nov. – urn:lsid:zoobank.org:act:C84F5038-F12C-48CC-9ED7-8DBE6BAE1D5CCephennium hamulatum Assing spec. nov. – urn:lsid:zoobank.org:act:FA4D9AB5-DAA3-4DE7-8064-5B98210F93D0Cephennium curvatum Assing spec. nov. – urn:lsid:zoobank.org:act:73B78F2A-4907-4334-B475-A59C7CD81063Cephennium selenanum Assing spec. nov. – urn:lsid:zoobank.org:act:E5B87D2D-9402-43F9-82E3-1DEF6D709DF1Cephennium latius Assing spec. nov. – urn:lsid:zoobank.org:act:8B3A0458-1D50-4551-BED6-D307750DD522Cephennium chanianum Assing spec. nov. – urn:lsid:zoobank.org:act:0C990A58-8107-4B07-87D5-FE0541CD444Euconnus zakrius Meybohm spec. nov. – urn:lsid:zoobank.org:act:506C3D6D-FD24-4484-813D-F00E761EFECBStenichnus brachati Meybohm spec. nov. – urn:lsid:zoobank.org:act:0D694A13-AB82-4398-AC2A-2E4D39B515FBStenichnus orientalis Meybohm spec. nov. – urn:lsid:zoobank.org:act:06558FCA-3A62-4019-BFB7-EF06448C1956Stenichnus aegialioides Meybohm spec. nov. – urn:lsid:zoobank.org:act:712D1FB1-7AB4-4C27-8CB2-05E07E8435FELeptomastax cretica Meybohm spec. nov. – urn:lsid:zoobank.org:act:444B05D8-E8CB-4F7F-A9A5-1695EB36C08ALeptomastax thriptica Meybohm spec. nov. – urn:lsid:zoobank.org:act:5EA83082-7F64-4122-852C-AECB11BF6D01Afropselaphus doernfeldae Brachat spec. nov. – urn:lsid:zoobank.org:act:96DFC249-A208-44CE-BC83-4BB829F6966BAfropselaphus assingi Brachat spec. nov. – urn:lsid:zoobank.org:act:A29A770B-1104-4BB0-BA7E-ADA1CB04D204Afropselaphus diktianus Brachat spec. nov. – urn:lsid:zoobank.org:act:AF308CB8-7539-4626-8E2CDD2A7E9B5052Afropselaphus thripticus Brachat spec. nov. – urn:lsid:zoobank.org:act:E38E8556-0E8F-4C12-BD99-3759694D8E82 Amauronyx chanianus Brachat spec. nov. – urn:lsid:zoobank.org:act:833A774F-4626-4CC8-8BE0-7B857E33EC43Amauronyx occidens Brachat spec. nov. – urn:lsid:zoobank.org:act:0545A123-B114-4014-A05D-2C5EF565D5D9Amauronyx askifouicus Brachat spec. nov. – urn:lsid:zoobank.org:act:7CE4D2AD-8F1E-408A-9112-5301AC6CC6AEBryaxis meybohmianus Brachat spec. nov. – urn:lsid:zoobank.org:act:FE6B56D3-E7A1-4F55-9587-ABC42768A1ACBythinus creticus Brachat spec. nov. – urn:lsid:zoobank.org:act:5A5439A5-BB04-41D0-897E-3769BA046964Euplectus assingi Brachat spec. nov. – urn:lsid:zoobank.org:act:B653CFCD-0DF4-4AC8-8BDC-64FCD2FB9599Faronus meybohmi Brachat spec. nov. – urn:lsid:zoobank.org:act:B80022A7-78AC-45E9-94A6-B3A31657DCF7Faronus lefkamontium Brachat spec. nov. – urn:lsid:zoobank.org:act:B5C36287-54F6-4CF0-B2BF-E3D8E4AF1029Faronus albimontium Brachat spec. nov. – urn:lsid:zoobank.org:act:9E7893E5-D3A1-4387-B179-AA51AB793FEDTychus chanianus Brachat spec. nov. – urn:lsid:zoobank.org:act:85D07E45-AEE2-4D13-9C26-18B353D1AD15Sepedophilus creticus Schülke spec. nov. – urn:lsid:zoobank.org:act:F2B971D6-B222-4823-A1BB-DF4B816F077

A comparison of third-generation semi-invasive arterial waveform analysis with thermodilution in patients undergoing coronary surgery

Uncalibrated semi-invasive continous monitoring of cardiac index (CI) has recently gained increasing interest. The aim of the present study was to compare the accuracy of CI determination based on arterial waveform analysis with transpulmonary thermodilution. Fifty patients scheduled for elective coronary surgery were studied after induction of anaesthesia and before and after cardiopulmonary bypass (CPB), respectively. Each patient was monitored with a central venous line, the PiCCO system, and the FloTrac/Vigileo-system. Measurements included CI derived by transpulmonary thermodilution and uncalibrated semi-invasive pulse contour analysis. Percentage changes of CI were calculated. There was a moderate, but significant correlation between pulse contour CI and thermodilution CI both before (r(2) = 0.72, P < 0.0001) and after (r(2) = 0.62, P < 0.0001) CPB, with a percentage error of 31% and 25%, respectively. Changes in pulse contour CI showed a significant correlation with changes in thermodilution CI both before (r(2) = 0.52, P < 0.0001) and after (r(2) = 0.67, P < 0.0001) CPB. Our findings demonstrated that uncalibrated semi-invasive monitoring system was able to reliably measure CI compared with transpulmonary thermodilution in patients undergoing elective coronary surgery. Furthermore, the semi-invasive monitoring device was able to track haemodynamic changes and trends

On the Staphylinidae of the Greek island Corfu (Insecta: Coleoptera)

Im Rahmen einer Exkursion auf der jonischen Insel Korfu (Griechenland) im spaten Fruhjahr 2017 wurden insgesamt nahezu 10.000 Staphyliniden aufgefunden. Das Material gehort zu mehr als 233 Arten. Weitere bisher unveroffentlichte Nachweise von 66 identifizierten Arten werden fur die Insel gemeldet. Zwei Arten werden beschrieben und abgebildet: Borboropora corcyrana Assing spec. nov. (Aleocharinae) und Ocypus corcyranus Assing spec. nov. (Staphylininae). Insgesamt 118 benannte Arten werden erstmals fur Korfu nachgewiesen; bei 21 dieser Arten handelt es sich gleichzeitig um Erstnachweise fur Griechenland. Ein Name wird revalidiert und sechs Namen werden synonymisiert: Euplectus jonicus Meggiolaro, 1966 (revalidiert) = E. jonicus corcyreus Meggiolaro, 1966, syn. nov.; Mycetoporus punctipennis Scriba, 1868 = M. insulanus Luze, 1901, syn. nov.; Anotylus tetracarinatus (Block, 1799) = A. corcyranus (Coiffait, 1968), syn. nov.; Bledius corniger Rosenhauer, 1856 = B. bubalus Gistel, 1857, syn. nov.; Paederus littoralis Gravenhorst, 1802 = P. pelikani Reitter, 1884, syn. nov.; Leptacinus batychrus (Gyllenhal, 1827) = Phacophallus corcyranus Bordoni, 2017, syn. nov. Einschlieslich als verlasslich eingestufter Literaturnachweise sind derzeit 446 benannte Arten (und mehr als zehn nicht benannte oder nicht identifierte Arten) von Korfu bekannt. Damit ist die Fauna dieser Insel erheblich artenreicher als die aller anderen Inseln des ostlichen Mittelmeerraums, einschlieslich der deutlich groseren Insel Zypern. Ein Katalog der Staphyliniden von Korfu wird erstellt. Die meisten der derzeit 18 ausschlieslich von Korfu nachgewiesenen Arten und Unterarten sind vermutlich nicht auf der Insel endemisch. Nomenklatorische Handlungen Borboropora corcyrana spec. nov. – urn:lsid:zoobank.org:act:8D35093D-8EBF-4E9C-9876-AB758F4FC973 Ocypus corcyranus spec. nov. – urn:lsid:zoobank.org:act:812099FA-F72A-41E5-B96B-258F8F48639AA study of nearly 10,000 specimens of Staphylinidae collected in the Ionian island Corfu, Greece, in late spring 2017 yielded more than 233 species. Additional, previously unpublished records of 66 named species are reported from the island. Two species are described and illustrated: Borboropora corcyrana Assing spec. nov. of the Aleocharinae and Ocypus corcyranus Assing spec. nov. of the Staphylininae. As many as 118 named species are reported from Corfu for the first time, 21 of these species represent first records from Greece. One name is revalidated and six names are synonymized: Euplectus jonicus Meggiolaro, 1966 (revalidated) = E. jonicus corcyreus Meggiolaro, 1966, syn. nov.; Mycetoporus punctipennis Scriba, 1868 = M. insulanus Luze, 1901, syn. nov.; Anotylus tetracarinatus (Block, 1799) = A. corcyranus (Coiffait, 1968), syn. nov.; Bledius corniger Rosenhauer, 1856 = B. bubalus Gistel, 1857, syn. nov.; Paederus littoralis Gravenhorst, 1802 = P. pelikani Reitter, 1884, syn. nov.; Leptacinus batychrus (Gyllenhal, 1827) = Phacophallus corcyranus Bordoni, 2017, syn. nov. Including reliable previous literature records and the new records reported in the present paper, 446 named species (plus additional unnamed species) are currently known from Corfu. Thus, the known fauna of this island is significantly more diverse than those of other East Mediterranean islands, including the much larger Cyprus. A checklist of the Staphylinidae fauna of Corfu is provided. Although at present 18 species and subspecies have been recorded exclusively from Corfu, most of them are unlikely to represent island endemics; three of these species are of doubtful taxonomic status. Nomenclatural Acts Borboropora corcyrana spec. nov. – urn:lsid:zoobank.org:act:8D35093D-8EBF-4E9C-9876-AB758F4FC973 Ocypus corcyranus spec. nov. – urn:lsid:zoobank.org:act:812099FA-F72A-41E5-B96B-258F8F48639

Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling

Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear. This study sought to examine whether hypothermia and the combination of hypothermia and pharmacological postconditioning are cardioprotective in a model of cardiopulmonary resuscitation following acute myocardial ischemia. Methodology/Principal Findings: Thirty pigs (28–34 kg) were subjected to cardiac arrest following left anterior descending coronary artery ischemia. After 7 minutes of ventricular fibrillation and 2 minutes of basic life support, advanced cardiac life support was started according to the current AHA guidelines. After successful return of spontaneous circulation (n = 21), coronary perfusion was reestablished after 60 minutes of occlusion, and animals were randomized to either normothermia at 38°C, hypothermia at 33°C or hypothermia at 33°C combined with sevoflurane (each group n = 7) for 24 hours. The effects on cardiac damage especially on inflammation, apoptosis, and remodeling were studied using cellular and molecular approaches. Five animals were sham operated. Animals treated with hypothermia had lower troponin T levels (p<0.01), reduced infarct size (34±7 versus 57±12%; p<0.05) and improved left ventricular function compared to normothermia (p<0.05). Hypothermia was associated with a reduction in: (i) immune cell infiltration, (ii) apoptosis, (iii) IL-1beta and IL-6 mRNA up-regulation, and (iv) IL-1beta protein expression (p<0.05). Moreover, decreased matrix metalloproteinase-9 activity was detected in the ischemic myocardium after treatment with mild hypothermia. Sevoflurane conferred additional protective effects although statistic significance was not reached. Conclusions/Significance: Hypothermia reduced myocardial damage and dysfunction after cardiopulmonary resuscitation possible via a reduced rate of apoptosis and pro-inflammatory cytokine expression

Canning meats

8 pages; includes photographs and drawing. This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu

Renoprotection by remote ischemic conditioning during elective coronary revascularization: A systematic review and meta-analysis of randomized controlled trials

BACKGROUND: Remote ischemic conditioning (RIC) has been recognized an emerging non-invasive approach for preventing acute kidney injury (AKI) in patients undergoing either elective coronary artery bypass graft (CABG) surgery or percutaneous coronary intervention (PCI). On the other hand, accumulating evidence has indicated the involving role of pre-CABG contrast usage for coronary angiography in post-surgery AKI risk. Along with the shortening time delay of CABG after coronary angiography, and the prevalent hybrid coronary revascularization (HCR), the AKI prevention by RIC has faced challenges following coronary revascuralization. METHODS: Randomized controlled trials (RCTs) were searched from Pubmed, EMBase, and Cochrane library (until May 2016). The primary outcome was postoperative AKI. The second outcomes were included the requirement for renal replacement therapy (RRT), and in-hospital or 30-day mortality. RESULTS: Twenty eligible RCTs (CABG, 3357 patients; PCI, 1501 patients) were selected. RIC significantly halved the incidence of AKI following PCI when compared with controls [n=1501; odds ratio (OR)=0.51; 95% CI, 0.32 to 0.82; P=0.006; I(2)=29.6%]. However, RIC did not affect the incidence of AKI following CABG (n=1850; OR=0.94; 95% CI, 0.73 to 1.19; P=0.586; I(2)=12.4%). The requirement for RRT and in-hospital mortality was not affected by RIC in CABG (n=2049, OR=1.04, P=0.87; n=1920, OR=0.89, P=0.7; respectively). CONCLUSIONS: Our meta-analysis suggests that RIC for preventing AKI following CABG has faced with challenges in terms of AKI, the requirement for RRT, and mortality. However, RIC shows a renoprotective benefit for PCI. Hence, our findings may infer the preserved renal effects of RIC in CABG with preconditioning before the coronary angiography, or in HCR