144 research outputs found
Scattering phases in quantum dots: an analysis based on lattice models
The properties of scattering phases in quantum dots are analyzed with the
help of lattice models. We first derive the expressions relating the different
scattering phases and the dot Green functions. We analyze in detail the Friedel
sum rule and discuss the deviation of the phase of the transmission amplitude
from the Friedel phase at the zeroes of the transmission. The occurrence of
such zeroes is related to the parity of the isolated dot levels. A statistical
analysis of the isolated dot wave-functions reveals the absence of significant
correlations in the parity for large disorder and the appearance, for weak
disorder, of certain dot states which are strongly coupled to the leads. It is
shown that large differences in the coupling to the leads give rise to an
anomalous charging of the dot levels. A mechanism for the phase lapse observed
experimentally based on this property is discussed and illustrated with model
calculations.Comment: 18 pages, 9 figures. to appear in Physical Review
Chaotic scattering with direct processes: A generalization of Poisson's kernel for non-unitary scattering matrices
The problem of chaotic scattering in presence of direct processes or prompt
responses is mapped via a transformation to the case of scattering in absence
of such processes for non-unitary scattering matrices, \tilde S. In the absence
of prompt responses, \tilde S is uniformly distributed according to its
invariant measure in the space of \tilde S matrices with zero average, < \tilde
S > =0. In the presence of direct processes, the distribution of \tilde S is
non-uniform and it is characterized by the average (\neq 0). In
contrast to the case of unitary matrices S, where the invariant measures of S
for chaotic scattering with and without direct processes are related through
the well known Poisson kernel, here we show that for non-unitary scattering
matrices the invariant measures are related by the Poisson kernel squared. Our
results are relevant to situations where flux conservation is not satisfied.
For example, transport experiments in chaotic systems, where gains or losses
are present, like microwave chaotic cavities or graphs, and acoustic or elastic
resonators.Comment: Added two appendices and references. Corrected typo
Vibrational spectrum of topologically disordered systems
The topological nature of the disorder of glasses and supercooled liquids
strongly affects their high-frequency dynamics. In order to understand its main
features, we analytically studied a simple topologically disordered model,
where the particles oscillate around randomly distributed centers, interacting
through a generic pair potential. We present results of a resummation of the
perturbative expansion in the inverse particle density for the dynamic
structure factor and density of states. This gives accurate results for the
range of densities found in real systems.Comment: Completely rewritten version, accepted in Physical Review Letter
Bosonizing one-dimensional cold atomic gases
We present results for the long-distance asymptotics of correlation functions
of mesoscopic one-dimensional systems with periodic and open (Dirichlet)
boundary conditions, as well as at finite temperature in the thermodynamic
limit. The results are obtained using Haldane's harmonic-fluid approach (also
known as ``bosonization''), and are valid for both bosons and fermions, in
weakly and strongly interacting regimes. The harmonic-fluid approach and the
method to compute the correlation functions using conformal transformations are
explained in great detail. As an application relevant to one-dimensional
systems of cold atomic gases, we consider the model of bosons interacting with
a zero-range potential. The Luttinger-liquid parameters are obtained from the
exact solution by solving the Bethe-ansatz equations in finite-size systems.
The range of applicability of the approach is discussed, and the prefactor of
the one-body density matrix of bosons is fixed by finding an appropriate
parametrization of the weak-coupling result. The formula thus obtained is shown
to be accurate, when compared with recent diffusion Montecarlo calculations,
within less than 10%. The experimental implications of these results for Bragg
scattering experiments at low and high momenta are also discussed.Comment: 39 pages + 14 EPS figures; typos corrected, references update
Mortality among patients with tuberculosis requiring intensive care: a retrospective cohort study
<p>Abstract</p> <p>Background</p> <p>To describe the characteristics of patients with tuberculosis (TB) requiring intensive care and to identify the factors that predicts in-hospital mortality in a city of a developing country with intermediate-to-high TB endemicity.</p> <p>Methods</p> <p>We conducted a retrospective, cohort study, between November 2005 and November 2007. The patients with TB requiring intensive care were included. Predictors of mortality were assessed. The primary outcome was the in-hospital mortality.</p> <p>Results</p> <p>During the study period, 67 patients with TB required intensive care. Of them, 62 (92.5%) had acute respiratory failure and required mechanical ventilation. Forty-four (65.7%) patients died. Coinfection with human immunodeficiency virus was present in 46 (68.7%) patients. Early intensive care unit admission and ventilator-associated pneumonia were independently associated with the in-hospital mortality.</p> <p>Conclusions</p> <p>In this study we found a high mortality rate in TB patients requiring intensive care, especially in those with an early ICU admission.</p
Acute kidney injury in children
Acute kidney injury (AKI) (previously called acute renal failure) is characterized by a reversible increase in the blood concentration of creatinine and nitrogenous waste products and by the inability of the kidney to regulate fluid and electrolyte homeostasis appropriately. The incidence of AKI in children appears to be increasing, and the etiology of AKI over the past decades has shifted from primary renal disease to multifactorial causes, particularly in hospitalized children. Genetic factors may predispose some children to AKI. Renal injury can be divided into pre-renal failure, intrinsic renal disease including vascular insults, and obstructive uropathies. The pathophysiology of hypoxia/ischemia-induced AKI is not well understood, but significant progress in elucidating the cellular, biochemical and molecular events has been made over the past several years. The history, physical examination, and laboratory studies, including urinalysis and radiographic studies, can establish the likely cause(s) of AKI. Many interventions such as ‘renal-dose dopamine’ and diuretic therapy have been shown not to alter the course of AKI. The prognosis of AKI is highly dependent on the underlying etiology of the AKI. Children who have suffered AKI from any cause are at risk for late development of kidney disease several years after the initial insult. Therapeutic interventions in AKI have been largely disappointing, likely due to the complex nature of the pathophysiology of AKI, the fact that the serum creatinine concentration is an insensitive measure of kidney function, and because of co-morbid factors in treated patients. Improved understanding of the pathophysiology of AKI, early biomarkers of AKI, and better classification of AKI are needed for the development of successful therapeutic strategies for the treatment of AKI
A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer
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