Pazarlamanın Şirketlerin İş Performansı Üzerindeki Etkisi: Bir Literatür Taraması

The technology-based global competition environment that pushes businesses to constructive transformation in order to ensure customer satisfaction has further increased the importance of marketing capabilities in business strategies. The purpose of the literature review is to summarize the previous studies about marketing-financial performance nexus. Studies that were published between 1969 and 2019 could be reached from the EBSCO database were included in the literature review. A significant number of studies conducted in different countries have shown that marketing spending is an investment that creates value for the company and has a positive impact on firm profitability, firm value or firm sales. This study contributes to the literature by summarizing the research findings on the effects of marketing investments on business performance.TR - Dizi

Hilbert basis of the Lipman semigroup

In this work, we give a new method to compute the Hilbert basis of the semigroup of certain positive divisors supported on the exceptional divisor of a normal surface singularity. Our approach is purely combinatorial which permits to avoid the long calculation of the invariants of the ring as it is presented in the work of Altinok and Tosun.Comment: In Theorem~4, the Cartesian product $S = S_1 \times S_2$ is replaced with a fiber product $S = S_1 \times_{\mathcal{E}} S_2$, thanks are due to Zach Teitler for his careful readin

Çocuklarda influenza A ve B enfeksiyonlarının klinik ve laboratuvar özelliklerinin karşılaştırılması

Aim: In this study, we aimed to compare the clinical and laboratory findings of Influenza A and Influenza B infections in children. Methods: The study included 1826 pediatric patients (aged <16 years) who were di¬agnosed with Influenza A (n=1400) and B (n=426) infections between 1 October 2019 and 30 April 2020. The patients were also divided into age groups: the age groups of 0–2 years, 3–9 years, and 10–16 years. The characteristic clinical and laboratory findings were compared. Results: Influenza A infection was significantly more common in patients aged <2 years and was significantly less common in patients aged 3–9 years. Body temperature was significantly higher in all age groups with Influenza A infection than in children with Influenza B infection. While leukocy¬tosis and lymphopenia were significantly more common in the Influenza A group, leukopenia and neutropenia were significantly more common in the Influenza B group. While acute otitis media was more common in Influenza A infection, myositis was more common in Influenza B infection. No significant difference was found between the Influenza A and B groups in terms of hospitalization rates. Of all patients, 98.3% were treated with oseltamivir. Conclusion: Our findings indicate that Influenza A and B infections are, in general, very similar in terms of symptoms. However, Influenza A infection is more common in very young children. It progresses with higher fever and is more frequently associated with pharyngeal hy¬peremia and acute otitis media, while leukopenia, neutropenia, conjunctivitis, nasal discharge, and myositis were found to be more common in Influenza B infection.Amaç: Bu çalışmada, çocuklarda İnfluenza A ve İnfluenza B enfeksiyonlarının klinik ve laboratuvar bulgularını karşılaştırmak amaçlanmıştır. Yöntem: Çalışma 1 Ekim 2019 ile 30 Nisan 2020 tarihleri arasında İnfluenza A (n=1400) ve B (n=426) enfeksiyonu tanısı almış 16 yaş altı 1826 çocuk hasta içerdi. Hastalar aynı zamanda yaş gruplarına ayrıldı: 0–2 (yıl) yaş grubu, 3–9 yaş grubu, ve 10–16 yaş grubu. Karakteristik klinik bulgu¬lar ve laboratuvar bulguları karşılaştırıldı. Bulgular: İnfluenza A enfeksiyonu <2 yaşındaki hastalarda anlamlı biçimde daha yaygın, 3–9 ya¬şındaki hastalarda anlamlı biçimde daha enderdi. Vücut sıcaklığı İnfluenza A enfeksiyonlu tüm yaş gruplarında İnfluenza B enfeksiyonlu çocuklara göre anlamlı biçimde daha yüksekti. İnfluenza A grubunda lökositoz ve lenfopeni anlamlı biçimde daha yaygınken, İnfluenza B grubunda lökopeni ve nötropeni anlamlı biçimde daha yaygındı. Akut orta kulak iltihabı İnfluenza A enfeksiyonunda daha yaygınken, miyozit İnfluenza B enfeksiyonunda daha yaygındı. Hastaneye yatış oranı açısından ise İnfluenza A ve B grupları arasında anlamlı fark bulunmadı. Tüm hastaların %98,3’ü oseltamivir ile tedavi edildi. Sonuç: Bulgularımız İnfluenza A ve B enfeksiyonlarının semptomlar açısından genel olarak çok benzer olduğuna işaret etmektedir. Bununla birlikte, İnfluenza A enfeksiyonu çok küçük çocuklarda daha yaygındır. Daha yüksek ateşle ilerler ve farengeal hiperemi ve akut orta kulak ilti¬habı daha sık görülür. Lökopeni, nötropeni, konjonktivit, burun akıntısı ve miyozitin ise İnfluenza B enfeksiyonunda daha yaygın olduğu tespit edilmiştir

Interview with Marjorie Harkins Buchanan Kiewit

In this interview with Julia Stringfellow, Marjorie Harkins Buchanan Kiewit, LU class of 1943, discusses her time as a student as well as her time on the Board of Trustees.https://lux.lawrence.edu/oralhistories/1036/thumbnail.jp

Parrhesia: A “discursive relationship ethics” in foucault’s philosophy

Parrhesia, Michel Foucault’nun yaşamının son birkaç yılında yaptığı çalışmalarda sıkça karşılaştığımız bir sözcüktür. Euripides’in tragedyalarından başlayarak tüm Antikçağ boyunca bu sözcüğün anlam bakımından karşıladığı tematik farklılıklarını irdeleyen Foucault’nun parrhesia çalışmaları, Bilme İradesi eseri ile Hazların Kullanımı ve Kendilik Kaygısı eserlerinin arasında bir geçiş soruşturması olarak karşımıza çıkmaktadır. Parrhesia, Antikçağ ahlakında öznenin kendisiyle ve başkalarıyla kurduğu etik ilişkinin en temel “kendilik pratikleri”nden biridir. Çalışmamızda, Foucault’nun “sözel ilişki etiği” olarak tanımladığı bu pratiğin genel hatlarını serimledikten sonra, öznenin kendisiyle kurduğu “kendilik ilişkisi” ile irtibatını, askesis ile ilişkisini ve bu sözel etik pratiğin Foucault’nun son döneminde yaptığı Antikçağ soruşturmasındaki yerini tartışıyoruz.Parrhesia is a Word, which we often encounter in Michel Foucault’s work in the last few years of his life. Foucault’s work on parrhesia is focused on examining the thematic differences of its meaning throughout the Antiquity starting with the tragedies of Euripides; and this body of work appears as a transition investigation between his Will of Knowing and his Usage of Pleasure and Anxiety of Self. Parrhesia is one of the most basic "self-practices" of the ethical relationship that the self establishes with itself and with others in antiquity ethics. In this study, we aim first to describe the main features of this practice, which Foucault defines as “discursive relationship ethics”, and then to discuss its relation with “self relation” which the self establishes with itself and the place of this ethics practice in Foucault’s Antiquity investigation in his last period of work

Can hematological parameters be used for differential diagnosis in rotavirus infection at any age of children? A 6-year outcomes from a tertiary referral center

Aim: Routine blood parameters are widely used to detect of infectious diseases. Our study aimed to investigate the hematological parameters changes in rotavirus (RV) acute gastroenteritis and to evaluate the value of these parameters in children. Methods: In our study, the hematological data of patients diagnosed with RV-positive acute gastroenteritis (RPAGE) and RV-negative acute gastroenteritis (RNAGE) were analyzed between 2015-2020. In addition to the data automatically measured by complete blood count, lymphocyte/monocyte ratio (LMR), neutrophil/lymphocyte ratio (NLR), mean platelet volume/platelet ratio (MPVPR) were calculated. All cases were evaluated in three different age groups (5-year-old). Results: The present study included 2,144 patients (340 children with RPAGE, 1,804 children with RNAGE). Red blood cell count, hemoglobin, and hematocrit were higher in cases over 1 year of age with RPAGE. The MPVPR was lower in all age groups with RPAGE. The cut-off values of MPVPR for predicting Rotavirus infection (RI) were 0.023 (5-year-old group). The LMR was lower and NLR was higher in cases over 1 year of age with RPAGE. The cut-off value of LMR for predicting RI were 1.99 (1-to 5-year-old group) and 0.96 (>5-year-old group). The cut-off value of NLR for predicting RI were 1.41 (1-to 5-year-old group), and 3.79 (>5-year-old group). Conclusion: The low MPVPR can be used as a hematological biomarker for the identification of RPAGE cases in all age groups. Low LMR and high NLR can indicate RPAGE cases in over 1 year of age

Development of a fast and low-cost qPCR assay for diagnosis of acute gas pharyngitis

Background: Group A streptococci (GAS) are the most common bacterial cause of acute pharyngitis and account for 15-30 % of cases of acute pharyngitis in children and 5-10 % of cases in adults. In this study, a real-time quantitative PCR (qPCR) based GAS detection assay in pharyngeal swab specimens was developed. Methods: The qPCR assay was compared with the gold standard bacterial culture and a rapid antigen detection test (RADT) to evaluate its clinical performance in 687 patients. The analytical sensitivity of the assay was 240 cfu/swab. Forty-five different potential cross-reacting organisms did not react with the test. Four different laboratories for the reproducibility studies were in 100 % (60/60) agreement for the contrived GAS positive and negative swab samples. Results: The relative sensitivities of the RADT and the qPCR test were 55.9 and 100 %; and the relative specificities were 100 and 96.3 %, respectively. Duration of the total assay for 24 samples including pre-analytical processing and analysis changed between 42 and 55 min depending on the type of qPCR instrument used. A simple DNA extraction method and a low qPCR volume made the developed assay an economical alternative for the GAS detection. Conclusion: We showed that the developed qPCR test is rapid, cheap, sensitive and specific and therefore can be used to replace both antigen detection and culture for diagnosis of acute GAS pharyngitis

Serum Uric Acid, Alanine Aminotransferase, Hemoglobin and Red Blood Cell Count Levels in Pseudoexfoliation Syndrome

. Purpose. The pathogenesis of pseudoexfoliation (PEX), the most common cause of secondary glaucoma, has not been clearly identified, but there is increasing evidence that points out the role of oxidative stress. The aim of this study is to evaluate some of the most commonly used blood parameters, hemoglobin (Hb), red blood cell count (RBC), alanine aminotransferase (ALT), and uric acid (UA) levels, in subjects with PEX. Materials and Methods. This study is performed in a state hospital between November 2011 and December 2012. Retrospective chart review of subjects who underwent cataract surgery was performed. Thirty-one healthy subjects with PEX and 34 healthy subjects without PEX were evaluated. Hb, RBC, ALT, and UA levels were recorded. Student&apos;s t-test was used to compare the two groups. Results. The mean age was 73.6 ± 14.1 years in PEX group and 70.1 ± 12.7 in control group ( = 0.293). Hb, RBC, ALT, and UA levels did not show a statistically significant difference among PEX and control groups ( &gt; 0.05 for all). Conclusion. Serum levels of Hb, RBC, ALT, and UA levels were similar in subjects with and without PEX. Further studies are needed to clarify the precise role of Hb, RBC, ALT, and UA in the pathogenesis of PEX